Sean B Rourke
Datos Biográficos
| ID | 142302 |
|---|---|
| NOMBRE | Sean B Rourke |
| NOMBRES | Sean B |
| APELLIDO | Rourke |
| FIRMA | ROURKE S B |
| AFILIACIONES | St. Michael's Hospital |
| ORCID | 0000-0001-6162-7358 |
| VERIFICADO | Sí |
| TOTAL DE OBRAS | 79 |
| TOTAL DE CITAS | 32 |
| TOTAL COMO AUTOR | 79 |
| TOTAL COMO EDITOR | 0 |
| PRIMER AÑO DE PUBLICACIÓN | 2004 |
| AÑO MÁS RECIENTE DE PUBLICACIÓN | 2026 |
| ÍNDICE H | 3 |
Supporting youth living with HIV transitioning to adult HIV care
A critical challenge for youth living with HIV is transitioning from pediatric to adult care, a period often marked by disrupted continuity and risks of stigma and isolation. Few Canadian programs address this gap. The HIV Youth Peer Engagement (HYPE) program, developed by the AIDS Committee of Durham Region seeks to address this issue using a peer-led model emphasizing education, mentorship, and community building. This article presents findings…
Awareness, acceptance, and impact of undetectable equals untransmittable (U = U) among people living with HIV across Canada
Undetectable equals Untransmittable (U = U) is a pivotal tool for HIV prevention, stigma reduction, and improving quality of life for people living with HIV. This study examined awareness, acceptance, and impact of U = U among people living with HIV across Canada, and explored differences across sociodemographic characteristics. From 2018-2024, 1,083 participants were recruited in-person and online using snowball sampling. Peer researchers conduc…
A prospective multi-site study to evaluate the performance and usability of an oral fluid-based HIV self-test in Canada
Overall, 951 participants were recruited and consented with 911 available for all analyses. With respect to sociodemographics: 84% of participants were between 18-45 years of age, 73% had at least a college education, 48% were Cis-male, 45% were employed; and 26% identified as White, 23% as African, Caribbean or Black, 5% as Indigenous [First Nations, Métis or Inuit], 33% as Asian, and 6% as LatinX. Primary efficacy analysis on the 911 who comple…
Diagnosis of Learning Disabilities but not Academic Difficulties Alone is Associated with Neurocognitive Impairment in People Living with HIV
Diagnosing HIV-associated neurocognitive disorder (HAND) is a complex process aimed at determining the role of HIV versus other causes of neurocognitive impairment. In treated people with living long-term HIV infection, this process is further complicated by the presence of multiple medical and psychiatric comorbidities and varied educational history. Evidence-based research is therefore needed to refine the 2007 HAND diagnostic criteria on how t…
Racial disparities in HIV pre-exposure prophylaxis (PrEP) awareness and uptake among white, Black, and Indigenous men in Canada
Community-based and public health interventions are immediately needed to increase PrEP awareness, access, and uptake for Black and Indigenous communities in Canada
Intersecting gender, ethnicity, and sexual orientation identities and HIV stigma
Stigma remains a significant burden for people living with HIV and while studies have examined the impacts of gender, ethnicity, and sexual orientation on stigma separately, little is known about how these factors may intersect and potentially exacerbate levels of stigma. This study examines how these intersecting social positions may relate to levels of internalised, enacted and anticipated HIV stigma. Participants were recruited in Ontario, Alb…
Mindfulness and cognitive training interventions that address intersecting cognitive and aging needs of older adults
Mindfulness and cognitive training interventions are promising models to address impacts (e.g., anxiety and stress) of cognitive impairment among older adults. Combining strategies may yield better outcomes than models offered in isolation. However, there are numerous uncertainties about these interventions, potential for combination, and implementation. Social workers are well placed to offer these interventions. Findings From an initial search …
The impact of determinants of health on the relationship between stigma and health in people living with HIV
Determinants of health are important drivers of health states, yet there is little work examining their role in the relationship between HIV stigma and health. This study uses moderation analysis to examine how determinants of health affect the relationship between enacted, internalized, and anticipated stigma and mental health. Quantitative data was collected on 337 participants in Ontario, Canada at baseline (t1) between August 2018 and Septemb…
The Role of Dimensions of Social Support in the Relationship Between Stigma and Mental Health
The cost of anticipating stigma
Levels of HIV stigma remain high, however there is a limited understanding around how different types of stigma interact to impact health. This study uses data from two time points to examine how enacted and internalized stigma lead to worse health through anticipated stigma as a mediator. We recruited 341 participants in Ontario, Canada to complete the HIV Stigma Index survey at baseline (t1) from September 2018 to August 2019 and follow up (t2)…
Using concept mapping to explore the challenges associated with affording and accessing medications among people living with HIV in Ontario, Canada
Antiretroviral medications are expensive, and people living with HIV often experience challenges accessing and paying for medication due to various obstacles. We used concept mapping to explore the challenges people living with HIV in Ontario, Canada, face when accessing medication. In brainstorming, 68 participants generated 447 statements in response to the focus prompt “Some people living with HIV have trouble getting and paying for prescripti…
An exploration of the fertility desires and intentions of men living with HIV in Ontario, Canada
Planning families is an important issue within the HIV community. The primary objective of this study was to explore the fertility desires and intentions of men living with HIV (MLWH). A cross-sectional survey containing 77 questions in 10 domains was developed, validated and administered to MLWH. The sample was stratified by sexual orientation, ethnicity, and city of residence. Logistic regression analyses were conducted to determine sociodemogr…
Assessing HIV provider knowledge, screening practices, and training needs for HIV-associated neurocognitive disorders. A short report
Management of HIV-associated neurocognitive disorders (HAND) is becoming increasingly important with HIV-positive people living normal life spans. We aimed to establish the level of HAND awareness among doctor and nurse occupational health practitioners, screening used to detect impairment, factors limiting screening for HAND, and training needs. One-hundred-and-five members of the nursing and physician professional societies for occupational hea…
Reporting on patients living with HIV “disengaging from care”. Who is actually “lost to follow-up”
Retention in care remains an important concern for health care providers. However, accurately identifying who is or is not retained in care can be problematic. Not all patients believed to be engaged in care are actually in care, and not all patients believed to be disengaged are truly disengaged. Identifying the status of individuals within populations is important for clinical, administrative and surveillance concerns. As part of the Linkage an…
Four-Year Trajectories of Health-Related Quality of Life in People Living with HIV
Despite significant advances in antiretroviral therapy, unmet basic needs can negatively impact health-related quality of life (HRQoL) in people living with HIV, especially as they age. We aimed to examine the effect of unmet basic needs across age groups on changes in HRQoL over a 4-year period in persons with HIV. Physical and mental HRQoL scores from the Positive Spaces, Healthy Spaces cohort interviewed in 2006 (n = 538), 2007 (n = 506), and …
An observed, prospective field study to evaluate the performance and acceptance of a blood-based HIV self-test in Canada
The addition of a regulatory-approved self-test into the Canadian HIV testing landscape could significantly increase HIV testing rates. Having a blood-based HIV self-test approved in Canada can offer an accurate, acceptable, and simple alternative to facility-based HIV testing, particularly when impacted by Coronavirus pandemic restrictions
Impact of experienced HIV stigma on health is mediated by internalized stigma and depression
We developed a mediation model to explain how HIV-related stigma negatively impacts health. We found that that enacted stigma, or experiences of prejudice or discrimination, can lead to internalized stigma, or internalization of negative thoughts regarding one's HIV status and/or increased depressive symptoms which then may lead to worse overall health. Highlighting the importance of internalized stigma and depression has the potential to shape t…
Supervised consumption service use and recent non-fatal overdose among people who inject drugs in Toronto, Canada
The Ontario Integrated Supervised Injection Services Cohort Study of People Who Inject Drugs in Toronto, Canada (OiSIS-Toronto)
The Ontario Integrated Supervised Injection Services cohort in Toronto, Canada (OiSIS-Toronto) is an open prospective cohort of people who inject drugs (PWID). OiSIS-Toronto was established to evaluate the impacts of supervised consumption services (SCS) integrated within three community health agencies on health status and service use. The cohort includes PWID who do and do not use SCS, recruited via self-referral, snowball sampling, and communi…
Universities without Walls
(1) Background: Although HIV has not diminished in importance in Canada, the field of HIV research remains small, and the graduate students who decide to pursue careers within it feel isolated and uncertain about their professional skills and opportunities. Universities Without Walls (UWW) was created in 2009 to help redress these shortcomings. This paper presents a case study of UWW, a non-credit training program for emerging HIV researchers in …
Housing Stability and Neurocognitive Functioning in Homeless Adults With Mental Illness
Objective: This study examined the association of housing stability with neurocognitive outcomes of a well-characterized sample of homeless adults with mental illness over 18 months and sought to identify demographic and clinical variables associated with changes in neurocognitive functioning. Method: A total of 902 participants in the At Home/Chez Soi study completed neuropsychological measures 6 and 24 months after study enrollment to assess ne…
Potential use of supervised injection services among people who inject drugs in a remote and mid-size Canadian setting
Our findings suggest that SIS could play a role in addressing the harms of injection drug use in remote and mid-sized settings particularly for those who inject in public, as well as women and those who inject alone, who report higher expected frequency of SIS use. Design preferences of local PWID, in addition to differences according to gender should be taken into consideration to maximize the uptake of SIS, alongside existing health and social …
Challenges with access to healthcare from the perspective of patients living with HIV
Accessing healthcare can be difficult but the barriers multiply for people living with HIV (PLHIV). To improve access and the health of PLHIV, we must consider their perspectives and use them to inform standard practice. A better understanding of the current literature related to healthcare access from the perspective of PLHIV, can help to identify evidence gaps and highlight research priorities and opportunities. To identify relevant peer-review…
Prevalence and predictors of food insecurity among people living with HIV affiliated with Aids service organizations in Ontario, Canada
Up to half of people living with HIV in resource-rich settings experience moderate to severe food insecurity. Food insecurity, in turn, has been linked to adverse health outcomes including poor antiretroviral adherence, poor HIV viral suppression, frailty, and mortality. We estimated the prevalence of food insecurity among 649 adults living with HIV and recruited from community-based AIDS service organizations in Ontario, Canada. Food security wa…
High retention in HIV care at a tertiary care centre in Toronto, Canada
Poor retention in HIV care is associated with poor clinical outcomes and mortality. Previous studies of predictors of poor retention have been conducted with a wide variety of populations, using different measures of retention, and occasionally have conflicting results. We studied demographic and psychosocial factors associated with inter-visit interval length in a setting of universal health care and modern cART. Patients attending ≥2 appointmen…
Between skepticism and empowerment
People living with HIV/AIDS (PHAs) in Canada are a highly researched population, yet their inclusion in the research process is minimal. Community‐based research (CBR) has become a recognized tool for addressing issues of power and exclusion within researcher/community relationships by inviting the community's equitable involvement as research partners. Within the context of HIV/AIDS research, this includes a commitment to the Greater Involvement…
HIV Positive People’s Perspectives on Canadian Criminal Law and Non-Disclosure
The largest survey to date of people living with HIV regarding attitudes toward criminalization of HIV non-disclosure, this study investigates: sources of legal information available to HIV-positive people; perceptions of how criminal prosecutions and media coverage affect understanding of rights and responsibilities of self and others; and where HIV-positive people themselves stand on the role the criminal justice system should play. While mains…
Not Just “A Roof over Your Head”
The literature has identified housing as a fundamental unmet need for people living with HIV; yet there has been little qualitative evidence exploring housing and HIV, particularly from a Canadian context. This paper focuses on our qualitative analyses of the housing experiences of 48 HIV-positive people living in Ontario. Findings from our interviews illustrate healthy housing as a dynamic interconnection between health, housing and other social…
Inequalities in Determinants of Health Among Aboriginal and Caucasian Persons Living With HIV/Aids in Ontario
I'm Just Forgetting and I Don't Know Why
HIV-associated neurocognitive disorder (HAND) is common, but the lived experience of HAND is not well-understood. In this descriptive qualitative study, we explored how adults with HAND view, manage, and obtain support for cognitive difficulties. We interviewed 25 participants (20% female; median age = 51 years) who were diagnosed with HAND using neuropsychological assessment and a clinical interview. Semistructured interviews, co-developed with …
Employment status is associated with both physical and mental health quality of life in people living with HIV
To evaluate the relationship between employment status and health-related quality of life (HRQOL) in HIV/AIDS. A total of 361 participants provided baseline data in the context of an ongoing cohort study examining the natural history of neurobehavioral functioning and its effects on HRQOL. We administered tests and collected laboratory data to determine demographic status, HIV disease markers, psychosocial symptom burden, neurocognitive function …
The Ontario Integrated Supervised Injection Services Cohort Study of People Who Inject Drugs in Toronto, Canada (OiSIS-Toronto)
The Ontario Integrated Supervised Injection Services cohort in Toronto, Canada (OiSIS-Toronto) is an open prospective cohort of people who inject drugs (PWID). OiSIS-Toronto was established to evaluate the impacts of supervised consumption services (SCS) integrated within three community health agencies on health status and service use. The cohort includes PWID who do and do not use SCS, recruited via self-referral, snowball sampling, and communi…
Somatic symptoms in a community sample of Ethiopian immigrants in Toronto, Canada
This study examines the occurrence and correlates of somatic symptoms in a random sample of 342 adult Ethiopian immigrants residing in Toronto, Canada. Somatic symptoms were derived from the somatization disorder module of the Diagnostic Interview Schedule. Nearly two-thirds (63.2%) of the study participants reported having had at least one of the symptoms and 12.9% reported having had five or more symptoms in the 12 months preceding their interv…
Factors Associated With the Psychological Impact of Severe Acute Respiratory Syndrome on Nurses and Other Hospital Workers in Toronto
OBJECTIVES: A survey was conducted to measure psychological stress in hospital workers and measure factors that may have mediated acute traumatic responses. METHODS: A self-report survey was completed by 1557 healthcare workers at three Toronto hospitals in May and June 2003. Psychological stress was measured with the Impact of Event Scale. Scales representing attitudes to the outbreak were derived by factor analysis of 76 items probing attitudes…
Long-Term Quality-of-Life Outcomes Among Adults Living with HIV in the Haart Era
Inside the Black Box
Fidelity measurement is an evolving field in mental health case management program evaluation. This article presents an exploratory study in which two separate fidelity measures, the Dartmouth Assertive Community Treatment Scale (DACTS) and the Key Component Profiles (KCP), were used to assess structure and process elements of three mental health case management programs. The programs were studied because they all provided services to seriously m…
The Use of the Multnomah Community Ability Scale as a Program Evaluation Tool
The Multnomah Community Ability Scale (MCAS) is a standardized measure of functioning of people with mental illness living in the community. This study assessed feasibility and utility of the MCAS for routine outcome monitoring of clients enrolled in intensive community support programs. Burden related to training and administration was assessed and scale properties were evaluated, using data collected from a multisite community mental health eva…
Long-term Psychological and Occupational Effects of Providing Hospital Healthcare during Sars Outbreak
Healthcare workers (HCWs) found the 2003 outbreak of severe acute respiratory syndrome (SARS) to be stressful, but the long-term impact is not known. From 13 to 26 months after the SARS outbreak, 769 HCWs at 9 Toronto hospitals that treated SARS patients and 4 Hamilton hospitals that did not treat SARS patients completed a survey of several adverse outcomes. Toronto HCWs reported significantly higher levels of burnout (p = 0.019), psychological d…
The greater involvement of people living with Aids principle
Drawing on the Greater Involvement of People with HIV/AIDS (GIPA) principle, the HIV/AIDS movement began to "democratize" research in Canada in the mid-1990s. To date, there is little evidence about the success of the community-based research (CBR) movement in relation to the implementation of GIPA. We draw on findings from a larger study examining barriers and facilitating factors in relation to HIV-related CBR in Ontario, Canada. An online surv…
Effect of Early versus Deferred Antiretroviral Therapy for HIV on Survival
BACKGROUND: The optimal time for the initiation of antiretroviral therapy for asymptomatic patients with human immunodeficiency virus (HIV) infection is uncertain. METHODS: We conducted two parallel analyses involving a total of 17,517 asymptomatic patients with HIV infection in the United States and Canada who received medical care during the period from 1996 through 2005. None of the patients had undergone previous antiretroviral therapy. In ea…
Community-based research in Aids-service organizations
BACKGROUND: Community-based research (CBR) approaches have become commonplace in many North American HIV communities. In many large urban centers, AIDS-service organizations (ASOs) have become active research hubs, advocating for research dollars in community settings. While ASOs have historically integrated local knowledge into their prevention, care and advocacy initiatives, many are now initiating or collaborating in research which addresses e…
Between skepticism and empowerment
People living with HIV/AIDS (PHAs) in Canada are a highly researched population, yet their inclusion in the research process is minimal. Community‐based research (CBR) has become a recognized tool for addressing issues of power and exclusion within researcher/community relationships by inviting the community's equitable involvement as research partners. Within the context of HIV/AIDS research, this includes a commitment to the Greater Involvement…
Impact of social support on cognitive symptom burden in HIV/Aids
As many as 50% of people living with HIV/AIDS report cognitive difficulties, which can be associated with objective neuropsychological impairments and depression. A number of studies have demonstrated an association between higher social support and lower rates of depression. Using a cross-sectional design, we examined the role social support may play in attenuating the effects of both neuropsychological status and depression on cognitive difficu…
Once Daily Dosing Improves Adherence to Antiretroviral Therapy
Somatic symptoms in a community sample of Ethiopian immigrants in Toronto, Canada
This study examines the occurrence and correlates of somatic symptoms in a random sample of 342 adult Ethiopian immigrants residing in Toronto, Canada. Somatic symptoms were derived from the somatization disorder module of the Diagnostic Interview Schedule. Nearly two-thirds (63.2%) of the study participants reported having had at least one of the symptoms and 12.9% reported having had five or more symptoms in the 12 months preceding their interv…
Depressive Symptoms, Stress and Resources Among Adult Immigrants Living with HIV
Mastery Moderates the Negative Effect of Stigma on Depressive Symptoms in People Living with HIV
Inequalities in Determinants of Health Among Aboriginal and Caucasian Persons Living With HIV/Aids in Ontario
Employment status is associated with both physical and mental health quality of life in people living with HIV
To evaluate the relationship between employment status and health-related quality of life (HRQOL) in HIV/AIDS. A total of 361 participants provided baseline data in the context of an ongoing cohort study examining the natural history of neurobehavioral functioning and its effects on HRQOL. We administered tests and collected laboratory data to determine demographic status, HIV disease markers, psychosocial symptom burden, neurocognitive function …
Comparisons of disparities and risks of HIV infection in black and other men who have sex with men in Canada, UK, and USA
Homeless and Housed Inpatients with Schizophrenia
Relationships Between Dimensions of Disability Experienced by Adults Living with HIV
Housing Characteristics and their Influence on Health-Related Quality of Life in Persons Living with HIV in Ontario, Canada
Although lack of housing is linked with adverse health outcomes, little is known about the impacts of the qualitative aspects of housing on health. This study examined the association between structural elements of housing, housing affordability, housing satisfaction and health-related quality of life over a 1-year period. Participants were 509 individuals living with HIV in Ontario, Canada. Regression analyses were conducted to examine relations…
Labor Force Participation and Health-Related Quality of Life in HIV-Positive Men Who Have Sex with Men
Impact of hepatitis B and C co-infection on health-related quality of life in HIV positive individuals
The MaBwana Black men's study
In Canada, there is a paucity of research aimed at understanding Black gay men and the antecedents to risk factors for HIV. This study is an attempt to move beyond risk factor analysis and explore the role of sexual and ethnic communities in the lives of these men. The study utilized a community-based research and critical race theory approach. Semi-structured interviews were conducted with eight key informants to augment our understanding of Bla…
Association of Returning to Work With Better Health in Working-Aged Adults
Objectives. We systematically reviewed the literature on the impact of returning to work on health among working-aged adults. Methods. We searched 6 electronic databases in 2005. We selected longitudinal studies that documented a transition from unemployment to employment and included a comparison group. Two reviewers independently appraised the retrieved literature for potential relevance and methodological quality. Results. Eighteen studies met…
Closing the Gap
BACKGROUND: Combination antiretroviral therapy (ART) has significantly increased survival among HIV-positive adults in the United States (U.S.) and Canada, but gains in life expectancy for this region have not been well characterized. We aim to estimate temporal changes in life expectancy among HIV-positive adults on ART from 2000-2007 in the U.S. and Canada. METHODS: Participants were from the North American AIDS Cohort Collaboration on Research…
Medicine (63 obras) · HIV/AIDS Research and Interventions (54 obras) · Psychology (44 obras) · Psychiatry (41 obras) · Gerontology (35 obras) · HIV, Drug Use, Sexual Risk (31 obras) · Family medicine (28 obras) · Public health (27 obras) · Demography (24 obras) · Mental health (22 obras)