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Berthold Langguth

Datos Biográficos

ID1565946
NOMBREBerthold Langguth
NOMBRESBerthold
APELLIDOLangguth
FIRMALANGGUTH B
AFILIACIONESUniversity of Regensburg
ORCID0000-0002-7066-510X
VERIFICADOSí
TOTAL DE OBRAS22
TOTAL DE CITAS0
OBRAS COMO AUTOR22
OBRAS COMO EDITOR0
PRIMER AÑO DE PUBLICACIÓN2012
AÑO MÁS RECIENTE DE PUBLICACIÓN2026
ÍNDICE H0
  • Feasibility of home-based accelerated intermittent theta-burst stimulation (aiTBS) for depression

    Open Access•Katharina Kerkel, Andreas Reißmann et al.•ARTICLE•Frontiers in Psychiatry•2026

    Our pilot data demonstrate the feasibility of home-based TMS using a conventional clinical device, while highlighting substantial technical and logistical limitations. These limitations underscore the urgent need for the development of lightweight, portable and patient-friendly TMS devices to facilitate the delivery of neurostimulation therapies beyond clinical settings. Further studies with larger samples are warranted, using randomized controll…

  • HSN—helping in mental distress

    Open Access•Marina Scheele, Sandra Appel et al.•ARTICLE•Frontiers in Public Health•2025

    Psychological first aid programs aim to train lay people to help others who are experiencing a mental health crisis or developing mental health problems. The current article introduces the new German psychological first aid training program HSN. The acronym HSN stands for “Helfen in Seelischer Not” (helping in mental distress) but also for the action chain “hear, speak, network.” The HSN program differs from other well-examined mental health firs…

  • Deep brain stimulation for obsessive compulsive disorder leads to symptom changes of comorbid irritable bowel syndrome

    Open Access•Mohamed A Abdelnaim, Tobias Hebel et al.•ARTICLE•Frontiers in Psychiatry•2025

    In this study, we found alleviation of IBS symptoms after DBS of the BNST, along with improvement in OCD symptoms. Future research using larger sample sizes should address whether the reductions are tied to the improvement of OCD symptoms or if DBS exerts positive effects on IBS independently of OCD symptoms

  • Reading between the lines

    Open Access•Irina Jarvers, Monika Sommer et al.•ARTICLE•Frontiers in Psychiatry•2025

    While the SST may not be robust enough to accurately identify autistic individuals on its own, it does offer clinicians valuable insights into how individuals interpret others' actions and whether they grasp the broader context of a story versus focusing solely on details

  • Burden of disease scenarios for 204 countries and territories, 2022–2050

    Open Access•Stein Emil Vollset, Hazim S Ababneh et al.•ARTICLE•The Lancet•2024

    BACKGROUND: Future trends in disease burden and drivers of health are of great interest to policy makers and the public at large. This information can be used for policy and long-term health investment, planning, and prioritisation. We have expanded and improved upon previous forecasts produced as part of the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) and provide a reference forecast (the most likely future), and alternativ…

  • Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990–2021

    Open Access•Michael Brauer, Gregory A Roth et al.•ARTICLE•The Lancet•2024

    BACKGROUND: Understanding the health consequences associated with exposure to risk factors is necessary to inform public health policy and practice. To systematically quantify the contributions of risk factor exposures to specific health outcomes, the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2021 aims to provide comprehensive estimates of exposure levels, relative health risks, and attributable burden of disease for 88 ri…

  • Global fertility in 204 countries and territories, 1950–2021, with forecasts to 2100

    Open Access•Natalia V Bhattacharjee, Austin E Schumacher et al.•ARTICLE•The Lancet•2024

    BACKGROUND: Accurate assessments of current and future fertility-including overall trends and changing population age structures across countries and regions-are essential to help plan for the profound social, economic, environmental, and geopolitical challenges that these changes will bring. Estimates and projections of fertility are necessary to inform policies involving resource and health-care needs, labour supply, education, gender equality,…

  • Global burden of 288 causes of death and life expectancy decomposition in 204 countries and territories and 811 subnational locations, 1990–2021

    Open Access•Mohsen Naghavi, Kanyin Liane Ong et al.•ARTICLE•The Lancet•2024

    BACKGROUND: Regular, detailed reporting on population health by underlying cause of death is fundamental for public health decision making. Cause-specific estimates of mortality and the subsequent effects on life expectancy worldwide are valuable metrics to gauge progress in reducing mortality rates. These estimates are particularly important following large-scale mortality spikes, such as the COVID-19 pandemic. When systematically analysed, mort…

  • Global age-sex-specific mortality, life expectancy, and population estimates in 204 countries and territories and 811 subnational locations, 1950–2021, and the impact of the Covid-19 pandemic

    Open Access•Austin E Schumacher, Hmwe Hmwe Kyu et al.•ARTICLE•The Lancet•2024

    BACKGROUND: Estimates of demographic metrics are crucial to assess levels and trends of population health outcomes. The profound impact of the COVID-19 pandemic on populations worldwide has underscored the need for timely estimates to understand this unprecedented event within the context of long-term population health trends. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2021 provides new demographic estimates for 204 cou…

  • Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (Dalys), and healthy life expectancy (Hale) for 371 diseases and injuries in 204 countries and territor…

    Open Access•Alize J Ferrari, Damian Francesco Santomauro et al.•ARTICLE•The Lancet•2024

    BACKGROUND: Detailed, comprehensive, and timely reporting on population health by underlying causes of disability and premature death is crucial to understanding and responding to complex patterns of disease and injury burden over time and across age groups, sexes, and locations. The availability of disease burden estimates can promote evidence-based interventions that enable public health researchers, policy makers, and other professionals to im…

  • Global, regional, and national burden of disorders affecting the nervous system, 1990–2021

    Open Access•Jaimie D Steinmetz, Katrin Seeher et al.•ARTICLE•The Lancet Neurology•2024

    BACKGROUND: Disorders affecting the nervous system are diverse and include neurodevelopmental disorders, late-life neurodegeneration, and newly emergent conditions, such as cognitive impairment following COVID-19. Previous publications from the Global Burden of Disease, Injuries, and Risk Factor Study estimated the burden of 15 neurological conditions in 2015 and 2016, but these analyses did not include neurodevelopmental disorders, as defined by…

  • Treating depression at home with transcranial direct current stimulation

    Open Access•Katharina Dragon, Mohamed A Abdelnaim et al.•ARTICLE•Frontiers in Psychiatry•2024

    Regular video consultations or other safety concepts are recommended regardless of the number of video sessions actually conducted. Home-based tDCS seems to be safe and handy in our feasibility study, warranting further investigation

  • Single sessions of transcranial direct current stimulation and transcranial random noise stimulation exert no effect on sleepiness in patients with narcolepsy and idiopathic hypersomnia

    Open Access•Michaela Hohenester, Berthold Langguth et al.•ARTICLE•Frontiers in Psychiatry•2023

    We could not demonstrate any clinically relevant effects of single sessions of tDCS or tRNS on objective or subjective measures of sleepiness in patients with hypersomnia. However, we cannot exclude that repeated sessions of tES may affect vigilance or sleepiness in hypersomniac patients

  • Deep brain stimulation for treatment resistant obsessive compulsive disorder; an observational study with ten patients under real-life conditions

    Open Access•Mohamed A Abdelnaim, Verena Lang-Hambauer et al.•ARTICLE•Frontiers in Psychiatry•2023

    Our results suggest that BNST-DBS can be effective for treatment-resistant OCD patients, as indicated by a reduction in symptoms and an overall improvement in functioning. Despite the need for additional research to define the patients' selection criteria, the most appropriate anatomical target, and the most effective stimulation parameters, improved patient access for this therapy should be established

  • Cognitive Behavioral Group Therapy for Chronic Tinnitus in a German Tertiary Clinical Real-World Setting

    Open Access•Martin Schecklmann, Franziska C Weber et al.•ARTICLE•International Journal of…•2023

    Cognitive behavioral therapy (CBT) was shown to be effective in reducing tinnitus-related distress in numerous controlled trials. Real-world data from tinnitus treatment centers are an important addition to controlled trials for demonstrating the ecological validity of the results from the randomized controlled trials. Thus, we provided the real-world data of 52 patients participating in CBT group therapies during the time period from 2010 to 201…

  • Low Sleep Satisfaction Is Related to High Disease Burden in Tinnitus

    Open Access•Franziska C Weber, Winfried Schlee et al.•ARTICLE•International Journal of…•2022

    Previous studies have shown a high prevalence of sleep disturbances in tinnitus patients. However, no study has yet evaluated subjective sleep satisfaction. The present study aimed to investigate associations of self-reported sleep satisfaction with sociodemographic factors, tinnitus-related distress, depression, and self-reported quality of life. This is a retrospective analysis of 2344 outpatients with tinnitus presenting at a tertiary German t…

  • Staying Connected

    Open Access•Astrid Lehner, Klaus Nuißl et al.•ARTICLE•Frontiers in Public Health•2020

    Health systems worldwide are challenged by the coronavirus pandemic and all medical specialties have struggle to meet the conflicting requirements for virus containment on the one hand and treatment of other medical conditions on the other. This holds true also for psychiatry. Per se , psychiatric patients are highly vulnerable to suffer from social isolation and loneliness. As a result of the Covid-19 pandemic and lockdown measures, unfortunatel…

  • Anti-Suicidal Efficacy of Repetitive Transcranial Magnetic Stimulation in Depressive Patients

    Open Access•Mohamed A Abdelnaim, Berthold Langguth et al.•ARTICLE•Frontiers in Psychiatry•2020

    Background: Suicide is a major public health problem. About 90% of suicide victims have one or more major psychiatric disorder, with a reported 20-fold increased risk for suicide in patients with affective disorders in comparison with healthy subjects. Repetitive transcranial magnetic stimulation (rTMS) has been established as an effective alternative or adjunctive treatment option for patients with depressive disorders, but little is known about…

  • Sars-CoV-2 Risk Management in Clinical Psychiatry

    Open Access•Peter M Kreuzer, Thomas C Baghai et al.•ARTICLE•Frontiers in Psychiatry•2020

    The pandemic spread of the corona virus SARS-CoV-2 has even-handedly shattered national and international health systems and economies almost in an instant. As numbers of infections and COVID-19-related deaths rise from day to day, fears and uncertainties on how to deal with this unknown threat are extremely present both for individuals and societies as a whole. In this manuscript, we aim to exemplarily describe the bullet points concerning (a) t…

  • Paired Associative Stimulation of the Temporal Cortex

    Open Access•Sarah Engel, Robert Markewitz et al.•ARTICLE•Frontiers in Psychiatry•2017

    Frequency-specific effects for the 20 Hz aSSR confirm the feasibility of auditory PAS and highlight the secondary auditory cortex as its target site, introducing new possible treatment protocols for patients suffering from tinnitus. The amplitude decrease can be explained by principles of spike timing-dependent plasticity and the superposition model of aSSR

  • Risk attitudes and birth order

    Open Access•Philipp Krause, Johannes Heindl et al.•ARTICLE•Journal of Health Psychology•2014•Referencias: 26

    Risk attitudes play important roles in health behavior and everyday decision making. It is unclear, however, whether these attitudes can be predicted from birth order. We investigated 200 mostly male volunteers from two distinct settings. After correcting for multiple comparisons, for the number of siblings and for confounding by gender, ordinal position predicted perception of health-related risks among participants in extreme sports ( p < .01).…

  • Transcutaneous Vagus Nerve Stimulation

    Open Access•Peter M Kreuzer, Michael Landgrebe et al.•ARTICLE•Frontiers in Psychiatry•2012

    To our knowledge this is one of the first studies investigating feasibility and safety of tVNS in a clinical sample. In those subjects with no known pre-existing cardiac pathology, preliminary data do not indicate arrhythmic effects of tVNS

Sin obras prominentes en esta página.

  • Transcutaneous Vagus Nerve Stimulation

    Open Access•Peter M Kreuzer, Michael Landgrebe et al.•ARTICLE•Frontiers in Psychiatry•2012

    To our knowledge this is one of the first studies investigating feasibility and safety of tVNS in a clinical sample. In those subjects with no known pre-existing cardiac pathology, preliminary data do not indicate arrhythmic effects of tVNS

  • Risk attitudes and birth order

    Open Access•Philipp Krause, Johannes Heindl et al.•ARTICLE•Journal of Health Psychology•2014•Referencias: 26

    Risk attitudes play important roles in health behavior and everyday decision making. It is unclear, however, whether these attitudes can be predicted from birth order. We investigated 200 mostly male volunteers from two distinct settings. After correcting for multiple comparisons, for the number of siblings and for confounding by gender, ordinal position predicted perception of health-related risks among participants in extreme sports ( p < .01).…

  • Paired Associative Stimulation of the Temporal Cortex

    Open Access•Sarah Engel, Robert Markewitz et al.•ARTICLE•Frontiers in Psychiatry•2017

    Frequency-specific effects for the 20 Hz aSSR confirm the feasibility of auditory PAS and highlight the secondary auditory cortex as its target site, introducing new possible treatment protocols for patients suffering from tinnitus. The amplitude decrease can be explained by principles of spike timing-dependent plasticity and the superposition model of aSSR

  • Staying Connected

    Open Access•Astrid Lehner, Klaus Nuißl et al.•ARTICLE•Frontiers in Public Health•2020

    Health systems worldwide are challenged by the coronavirus pandemic and all medical specialties have struggle to meet the conflicting requirements for virus containment on the one hand and treatment of other medical conditions on the other. This holds true also for psychiatry. Per se , psychiatric patients are highly vulnerable to suffer from social isolation and loneliness. As a result of the Covid-19 pandemic and lockdown measures, unfortunatel…

  • Anti-Suicidal Efficacy of Repetitive Transcranial Magnetic Stimulation in Depressive Patients

    Open Access•Mohamed A Abdelnaim, Berthold Langguth et al.•ARTICLE•Frontiers in Psychiatry•2020

    Background: Suicide is a major public health problem. About 90% of suicide victims have one or more major psychiatric disorder, with a reported 20-fold increased risk for suicide in patients with affective disorders in comparison with healthy subjects. Repetitive transcranial magnetic stimulation (rTMS) has been established as an effective alternative or adjunctive treatment option for patients with depressive disorders, but little is known about…

  • Sars-CoV-2 Risk Management in Clinical Psychiatry

    Open Access•Peter M Kreuzer, Thomas C Baghai et al.•ARTICLE•Frontiers in Psychiatry•2020

    The pandemic spread of the corona virus SARS-CoV-2 has even-handedly shattered national and international health systems and economies almost in an instant. As numbers of infections and COVID-19-related deaths rise from day to day, fears and uncertainties on how to deal with this unknown threat are extremely present both for individuals and societies as a whole. In this manuscript, we aim to exemplarily describe the bullet points concerning (a) t…

  • Low Sleep Satisfaction Is Related to High Disease Burden in Tinnitus

    Open Access•Franziska C Weber, Winfried Schlee et al.•ARTICLE•International Journal of…•2022

    Previous studies have shown a high prevalence of sleep disturbances in tinnitus patients. However, no study has yet evaluated subjective sleep satisfaction. The present study aimed to investigate associations of self-reported sleep satisfaction with sociodemographic factors, tinnitus-related distress, depression, and self-reported quality of life. This is a retrospective analysis of 2344 outpatients with tinnitus presenting at a tertiary German t…

  • Single sessions of transcranial direct current stimulation and transcranial random noise stimulation exert no effect on sleepiness in patients with narcolepsy and idiopathic hypersomnia

    Open Access•Michaela Hohenester, Berthold Langguth et al.•ARTICLE•Frontiers in Psychiatry•2023

    We could not demonstrate any clinically relevant effects of single sessions of tDCS or tRNS on objective or subjective measures of sleepiness in patients with hypersomnia. However, we cannot exclude that repeated sessions of tES may affect vigilance or sleepiness in hypersomniac patients

  • Deep brain stimulation for treatment resistant obsessive compulsive disorder; an observational study with ten patients under real-life conditions

    Open Access•Mohamed A Abdelnaim, Verena Lang-Hambauer et al.•ARTICLE•Frontiers in Psychiatry•2023

    Our results suggest that BNST-DBS can be effective for treatment-resistant OCD patients, as indicated by a reduction in symptoms and an overall improvement in functioning. Despite the need for additional research to define the patients' selection criteria, the most appropriate anatomical target, and the most effective stimulation parameters, improved patient access for this therapy should be established

  • Cognitive Behavioral Group Therapy for Chronic Tinnitus in a German Tertiary Clinical Real-World Setting

    Open Access•Martin Schecklmann, Franziska C Weber et al.•ARTICLE•International Journal of…•2023

    Cognitive behavioral therapy (CBT) was shown to be effective in reducing tinnitus-related distress in numerous controlled trials. Real-world data from tinnitus treatment centers are an important addition to controlled trials for demonstrating the ecological validity of the results from the randomized controlled trials. Thus, we provided the real-world data of 52 patients participating in CBT group therapies during the time period from 2010 to 201…

  • Burden of disease scenarios for 204 countries and territories, 2022–2050

    Open Access•Stein Emil Vollset, Hazim S Ababneh et al.•ARTICLE•The Lancet•2024

    BACKGROUND: Future trends in disease burden and drivers of health are of great interest to policy makers and the public at large. This information can be used for policy and long-term health investment, planning, and prioritisation. We have expanded and improved upon previous forecasts produced as part of the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) and provide a reference forecast (the most likely future), and alternativ…

  • Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990–2021

    Open Access•Michael Brauer, Gregory A Roth et al.•ARTICLE•The Lancet•2024

    BACKGROUND: Understanding the health consequences associated with exposure to risk factors is necessary to inform public health policy and practice. To systematically quantify the contributions of risk factor exposures to specific health outcomes, the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2021 aims to provide comprehensive estimates of exposure levels, relative health risks, and attributable burden of disease for 88 ri…

  • Global fertility in 204 countries and territories, 1950–2021, with forecasts to 2100

    Open Access•Natalia V Bhattacharjee, Austin E Schumacher et al.•ARTICLE•The Lancet•2024

    BACKGROUND: Accurate assessments of current and future fertility-including overall trends and changing population age structures across countries and regions-are essential to help plan for the profound social, economic, environmental, and geopolitical challenges that these changes will bring. Estimates and projections of fertility are necessary to inform policies involving resource and health-care needs, labour supply, education, gender equality,…

  • Global burden of 288 causes of death and life expectancy decomposition in 204 countries and territories and 811 subnational locations, 1990–2021

    Open Access•Mohsen Naghavi, Kanyin Liane Ong et al.•ARTICLE•The Lancet•2024

    BACKGROUND: Regular, detailed reporting on population health by underlying cause of death is fundamental for public health decision making. Cause-specific estimates of mortality and the subsequent effects on life expectancy worldwide are valuable metrics to gauge progress in reducing mortality rates. These estimates are particularly important following large-scale mortality spikes, such as the COVID-19 pandemic. When systematically analysed, mort…

  • Global age-sex-specific mortality, life expectancy, and population estimates in 204 countries and territories and 811 subnational locations, 1950–2021, and the impact of the Covid-19 pandemic

    Open Access•Austin E Schumacher, Hmwe Hmwe Kyu et al.•ARTICLE•The Lancet•2024

    BACKGROUND: Estimates of demographic metrics are crucial to assess levels and trends of population health outcomes. The profound impact of the COVID-19 pandemic on populations worldwide has underscored the need for timely estimates to understand this unprecedented event within the context of long-term population health trends. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2021 provides new demographic estimates for 204 cou…

  • Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (Dalys), and healthy life expectancy (Hale) for 371 diseases and injuries in 204 countries and territor…

    Open Access•Alize J Ferrari, Damian Francesco Santomauro et al.•ARTICLE•The Lancet•2024

    BACKGROUND: Detailed, comprehensive, and timely reporting on population health by underlying causes of disability and premature death is crucial to understanding and responding to complex patterns of disease and injury burden over time and across age groups, sexes, and locations. The availability of disease burden estimates can promote evidence-based interventions that enable public health researchers, policy makers, and other professionals to im…

  • Global, regional, and national burden of disorders affecting the nervous system, 1990–2021

    Open Access•Jaimie D Steinmetz, Katrin Seeher et al.•ARTICLE•The Lancet Neurology•2024

    BACKGROUND: Disorders affecting the nervous system are diverse and include neurodevelopmental disorders, late-life neurodegeneration, and newly emergent conditions, such as cognitive impairment following COVID-19. Previous publications from the Global Burden of Disease, Injuries, and Risk Factor Study estimated the burden of 15 neurological conditions in 2015 and 2016, but these analyses did not include neurodevelopmental disorders, as defined by…

  • Treating depression at home with transcranial direct current stimulation

    Open Access•Katharina Dragon, Mohamed A Abdelnaim et al.•ARTICLE•Frontiers in Psychiatry•2024

    Regular video consultations or other safety concepts are recommended regardless of the number of video sessions actually conducted. Home-based tDCS seems to be safe and handy in our feasibility study, warranting further investigation

  • HSN—helping in mental distress

    Open Access•Marina Scheele, Sandra Appel et al.•ARTICLE•Frontiers in Public Health•2025

    Psychological first aid programs aim to train lay people to help others who are experiencing a mental health crisis or developing mental health problems. The current article introduces the new German psychological first aid training program HSN. The acronym HSN stands for “Helfen in Seelischer Not” (helping in mental distress) but also for the action chain “hear, speak, network.” The HSN program differs from other well-examined mental health firs…

  • Deep brain stimulation for obsessive compulsive disorder leads to symptom changes of comorbid irritable bowel syndrome

    Open Access•Mohamed A Abdelnaim, Tobias Hebel et al.•ARTICLE•Frontiers in Psychiatry•2025

    In this study, we found alleviation of IBS symptoms after DBS of the BNST, along with improvement in OCD symptoms. Future research using larger sample sizes should address whether the reductions are tied to the improvement of OCD symptoms or if DBS exerts positive effects on IBS independently of OCD symptoms

  • Reading between the lines

    Open Access•Irina Jarvers, Monika Sommer et al.•ARTICLE•Frontiers in Psychiatry•2025

    While the SST may not be robust enough to accurately identify autistic individuals on its own, it does offer clinicians valuable insights into how individuals interpret others' actions and whether they grasp the broader context of a story versus focusing solely on details

  • Feasibility of home-based accelerated intermittent theta-burst stimulation (aiTBS) for depression

    Open Access•Katharina Kerkel, Andreas Reißmann et al.•ARTICLE•Frontiers in Psychiatry•2026

    Our pilot data demonstrate the feasibility of home-based TMS using a conventional clinical device, while highlighting substantial technical and logistical limitations. These limitations underscore the urgent need for the development of lightweight, portable and patient-friendly TMS devices to facilitate the delivery of neurostimulation therapies beyond clinical settings. Further studies with larger samples are warranted, using randomized controll…

Medicine (21 obras) · Psychology (13 obras) · Psychiatry (11 obras) · Disease (10 obras) · Environmental health (7 obras) · Population (7 obras) · Stimulation (7 obras) · Burden of disease (6 obras) · Clinical Psychology (6 obras) · Internal Medicine (6 obras)

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