Holger J Schünemann
Datos Biográficos
| ID | 1743778 |
|---|---|
| NOMBRE | Holger J Schünemann |
| NOMBRES | Holger J |
| APELLIDO | Schünemann |
| FIRMA | SCHÜNEMANN H J |
| AFILIACIONES | McMaster University |
| ORCID | 0000-0003-3211-8479 |
| VERIFICADO | Sí |
| TOTAL DE OBRAS | 22 |
| TOTAL DE CITAS | 12 |
| TOTAL COMO AUTOR | 22 |
| TOTAL COMO EDITOR | 0 |
| PRIMER AÑO DE PUBLICACIÓN | 2004 |
| AÑO MÁS RECIENTE DE PUBLICACIÓN | 2025 |
| ÍNDICE H | 2 |
Shifting the centre of gravity in the global evidence ecosystem for health
BOX Global challenges in recent years, including humanitarian, climate-related and public health crises, have highlighted critical weaknesses in the application of evidence in decision-making, both locally and globally
Non-Steroidal Anti-Inflammatory Drugs for the Prevention of Colorectal Cancer
User-experience testing of an evidence-to-decision framework for selecting essential medicines
Essential medicine lists (EMLs) are important medicine prioritization tools used by the World Health Organization (WHO) EML and over 130 countries. The criteria used by WHO’s Expert Committee on the Selection and Use of Essential Medicines has parallels to the GRADE Evidence-to-Decision (EtD) frameworks. In this study, we explored the EtD frameworks and a visual abstract as adjunctive tools to strengthen the integrate evidence and improve the tra…
Comparing the usability of the World Health Organization’s conventional tuberculosis guidelines to the eTB recommendations map
Best practices for the dissemination of global health guidelines has not undergone rigorous research. We used a new approach to digitizing World Health Organization (WHO) global tuberculosis guideline recommendations (eTB RecMap) and compared its usability to the conventional method of accessing TB recommendations using the WHO website. We conducted a two-arm superiority randomised controlled trial using a survey among global stakeholders who wer…
Covid-19 Vaccines Safety Tracking (CoVaST)
CoVaST is the first independent study aiming to monitor the side effects of COVID-19 vaccines following booster doses, and the long-term safety and effectiveness of said vaccines
AI’s gonna have an impact on everything in society, so it has to have an impact on public health”
Experts are cautiously optimistic about AI's impacts on public health practice, particularly for improving disease surveillance. However, they perceived substantial barriers, such as a lack of available expertise, and risks, including inadequate regulation. Therefore, investment and research into AI for public health practice would likely be beneficial. However, increased access to high-quality data, research and education regarding the limitatio…
Physical distancing, face masks, and eye protection to prevent person-to-person transmission of Sars-CoV-2 and Covid-19
Safe management of bodies of deceased persons with suspected or confirmed Covid-19
Methods used in adaptation of health–related guidelines
BACKGROUND: Adaptation refers to the systematic approach for considering the endorsement or modification of recommendations produced in one setting for application in another as an alternative to de novo development. OBJECTIVE: To describe and assess the methods used for adapting health-related guidelines published in peer-reviewed journals, and to assess the quality of the resulting adapted guidelines. METHODS: We searched Medline and Embase up …
Considering health equity when moving from evidence-based guideline recommendations to implementation
Health Policy & Planning doi: 10.1093/heapol/czx126 The funding statement for this article has been updated to contain the following acknowledgement: Srinivasa Vittal Katikireddi acknowledges funding from a NRS Senior Clinical Fellowship (SCAF/15/02), the UK Medical Research Council (MC_UU_12017/13 & MC_UU_12017/15) and the Scottish Government Chief Scientist Office (SPHSU13 & SPHSU15).
Considering health equity when moving from evidence-based guideline recommendations to implementation
The availability of evidence-based guidelines does not ensure their implementation and use in clinical practice or policy making. Inequities in health have been defined as those inequalities within or between populations that are avoidable, unnecessary and also unjust and unfair. Evidence-based clinical practice and public health guidelines ('guidelines') can be used to target health inequities experienced by disadvantaged populations, although g…
Robins-I
Non-randomised studies of the effects of interventions are critical to many areas of healthcare evaluation, but their results may be biased. It is therefore important to understand and appraise their strengths and weaknesses. We developed ROBINS-I (“Risk Of Bias In Non-randomised Studies - of Interventions”), a new tool for evaluating risk of bias in estimates of the comparative effectiveness (harm or benefit) of interventions from studies that d…
Values and preferences for oral antithrombotic therapy in patients with atrial fibrillation
BACKGROUND: Exploration of values and preferences in the context of anticoagulation therapy for atrial fibrillation (AF) remains limited. To better characterize the distribution of patient and physician values and preferences relevant to decisions regarding anticoagulation in patients with AF, we conducted interviews with patients at risk of developing AF and physicians who manage patients with AF. METHODS: We interviewed 96 outpatients and 96 ph…
Consumer involvement in systematic reviews of comparative effectiveness research
Background The Institute of Medicine recently recommended that comparative effectiveness research (CER) should involve input from consumers. While systematic reviews are a major component of CER, little is known about consumer involvement. Objective To explore current approaches to involving consumers in US‐based and key international organizations and groups conducting or commissioning systematic reviews (‘organizations’). Design In‐depth, semi‐…
The Association of Depressive Symptoms and Pulmonary Function in Healthy Adults
OBJECTIVE: Chronic lung disease is exacerbated by comorbid psychiatric issues and treatment of depression may improve disease symptoms. We sought to add to the literature as to whether depression is associated with pulmonary function in healthy adults. METHODS: In 2551 healthy adults from New York State, we studied the association of depression via the Center for Epidemiologic Studies Depression scale (CES-D) scale score and forced expiratory vol…
GRADE guidelines
The GRADE approach and Bradford Hill's criteria for causation
This article describes how the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach to grading the quality of evidence and strength of recommendations considers the Bradford Hill criteria for causation and how GRADE may relate to questions in public health. A primary concern in public health is that evidence from non-randomised studies may provide a more adequate or best available measure of a public health strategy'…
Grade
Guidelines are inconsistent in how they rate the quality of evidence and the strength of recommendations. This article explores the advantages of the GRADE system, which is increasingly being adopted by organisations worldwide
Post-graduation migration intentions of students of Lebanese medical schools
An alarming percentage of students of Lebanese medical schools intend to migrate for post graduate training, mainly to the US. A minority intends to return directly to Lebanon after finishing training abroad
Why are you draining your brain? Factors underlying decisions of graduating Lebanese medical students to migrate
Do Clinical Marker States Improve Responsiveness and Construct Validity of the Standard Gamble and Feeling Thermometer
A Randomized Multicenter Trial to Evaluate Simple Utility Elicitation Techniques in Patients With Gastroesophageal Reflux Disease
BACKGROUND: Despite recommendations that patients rating their own health using utility and preference measures such as the feeling thermometer (FT) and standard gamble (SG) should also rate hypothetical marker states, little evidence supports marker state use. We evaluated whether the administration of marker states improves measurement properties of the FT and SG. METHODS: We randomized 217 patients with gastroesophageal reflux disease to compl…
Why are you draining your brain? Factors underlying decisions of graduating Lebanese medical students to migrate
The GRADE approach and Bradford Hill's criteria for causation
This article describes how the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach to grading the quality of evidence and strength of recommendations considers the Bradford Hill criteria for causation and how GRADE may relate to questions in public health. A primary concern in public health is that evidence from non-randomised studies may provide a more adequate or best available measure of a public health strategy'…
Considering health equity when moving from evidence-based guideline recommendations to implementation
The availability of evidence-based guidelines does not ensure their implementation and use in clinical practice or policy making. Inequities in health have been defined as those inequalities within or between populations that are avoidable, unnecessary and also unjust and unfair. Evidence-based clinical practice and public health guidelines ('guidelines') can be used to target health inequities experienced by disadvantaged populations, although g…
A Randomized Multicenter Trial to Evaluate Simple Utility Elicitation Techniques in Patients With Gastroesophageal Reflux Disease
BACKGROUND: Despite recommendations that patients rating their own health using utility and preference measures such as the feeling thermometer (FT) and standard gamble (SG) should also rate hypothetical marker states, little evidence supports marker state use. We evaluated whether the administration of marker states improves measurement properties of the FT and SG. METHODS: We randomized 217 patients with gastroesophageal reflux disease to compl…
Do Clinical Marker States Improve Responsiveness and Construct Validity of the Standard Gamble and Feeling Thermometer
Why are you draining your brain? Factors underlying decisions of graduating Lebanese medical students to migrate
Grade
Guidelines are inconsistent in how they rate the quality of evidence and the strength of recommendations. This article explores the advantages of the GRADE system, which is increasingly being adopted by organisations worldwide
Post-graduation migration intentions of students of Lebanese medical schools
An alarming percentage of students of Lebanese medical schools intend to migrate for post graduate training, mainly to the US. A minority intends to return directly to Lebanon after finishing training abroad
GRADE guidelines
The GRADE approach and Bradford Hill's criteria for causation
This article describes how the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach to grading the quality of evidence and strength of recommendations considers the Bradford Hill criteria for causation and how GRADE may relate to questions in public health. A primary concern in public health is that evidence from non-randomised studies may provide a more adequate or best available measure of a public health strategy'…
Consumer involvement in systematic reviews of comparative effectiveness research
Background The Institute of Medicine recently recommended that comparative effectiveness research (CER) should involve input from consumers. While systematic reviews are a major component of CER, little is known about consumer involvement. Objective To explore current approaches to involving consumers in US‐based and key international organizations and groups conducting or commissioning systematic reviews (‘organizations’). Design In‐depth, semi‐…
The Association of Depressive Symptoms and Pulmonary Function in Healthy Adults
OBJECTIVE: Chronic lung disease is exacerbated by comorbid psychiatric issues and treatment of depression may improve disease symptoms. We sought to add to the literature as to whether depression is associated with pulmonary function in healthy adults. METHODS: In 2551 healthy adults from New York State, we studied the association of depression via the Center for Epidemiologic Studies Depression scale (CES-D) scale score and forced expiratory vol…
Values and preferences for oral antithrombotic therapy in patients with atrial fibrillation
BACKGROUND: Exploration of values and preferences in the context of anticoagulation therapy for atrial fibrillation (AF) remains limited. To better characterize the distribution of patient and physician values and preferences relevant to decisions regarding anticoagulation in patients with AF, we conducted interviews with patients at risk of developing AF and physicians who manage patients with AF. METHODS: We interviewed 96 outpatients and 96 ph…
Robins-I
Non-randomised studies of the effects of interventions are critical to many areas of healthcare evaluation, but their results may be biased. It is therefore important to understand and appraise their strengths and weaknesses. We developed ROBINS-I (“Risk Of Bias In Non-randomised Studies - of Interventions”), a new tool for evaluating risk of bias in estimates of the comparative effectiveness (harm or benefit) of interventions from studies that d…
Methods used in adaptation of health–related guidelines
BACKGROUND: Adaptation refers to the systematic approach for considering the endorsement or modification of recommendations produced in one setting for application in another as an alternative to de novo development. OBJECTIVE: To describe and assess the methods used for adapting health-related guidelines published in peer-reviewed journals, and to assess the quality of the resulting adapted guidelines. METHODS: We searched Medline and Embase up …
Considering health equity when moving from evidence-based guideline recommendations to implementation
Health Policy & Planning doi: 10.1093/heapol/czx126 The funding statement for this article has been updated to contain the following acknowledgement: Srinivasa Vittal Katikireddi acknowledges funding from a NRS Senior Clinical Fellowship (SCAF/15/02), the UK Medical Research Council (MC_UU_12017/13 & MC_UU_12017/15) and the Scottish Government Chief Scientist Office (SPHSU13 & SPHSU15).
Considering health equity when moving from evidence-based guideline recommendations to implementation
The availability of evidence-based guidelines does not ensure their implementation and use in clinical practice or policy making. Inequities in health have been defined as those inequalities within or between populations that are avoidable, unnecessary and also unjust and unfair. Evidence-based clinical practice and public health guidelines ('guidelines') can be used to target health inequities experienced by disadvantaged populations, although g…
Physical distancing, face masks, and eye protection to prevent person-to-person transmission of Sars-CoV-2 and Covid-19
Safe management of bodies of deceased persons with suspected or confirmed Covid-19
Covid-19 Vaccines Safety Tracking (CoVaST)
CoVaST is the first independent study aiming to monitor the side effects of COVID-19 vaccines following booster doses, and the long-term safety and effectiveness of said vaccines
AI’s gonna have an impact on everything in society, so it has to have an impact on public health”
Experts are cautiously optimistic about AI's impacts on public health practice, particularly for improving disease surveillance. However, they perceived substantial barriers, such as a lack of available expertise, and risks, including inadequate regulation. Therefore, investment and research into AI for public health practice would likely be beneficial. However, increased access to high-quality data, research and education regarding the limitatio…
Comparing the usability of the World Health Organization’s conventional tuberculosis guidelines to the eTB recommendations map
Best practices for the dissemination of global health guidelines has not undergone rigorous research. We used a new approach to digitizing World Health Organization (WHO) global tuberculosis guideline recommendations (eTB RecMap) and compared its usability to the conventional method of accessing TB recommendations using the WHO website. We conducted a two-arm superiority randomised controlled trial using a survey among global stakeholders who wer…
User-experience testing of an evidence-to-decision framework for selecting essential medicines
Essential medicine lists (EMLs) are important medicine prioritization tools used by the World Health Organization (WHO) EML and over 130 countries. The criteria used by WHO’s Expert Committee on the Selection and Use of Essential Medicines has parallels to the GRADE Evidence-to-Decision (EtD) frameworks. In this study, we explored the EtD frameworks and a visual abstract as adjunctive tools to strengthen the integrate evidence and improve the tra…
Shifting the centre of gravity in the global evidence ecosystem for health
BOX Global challenges in recent years, including humanitarian, climate-related and public health crises, have highlighted critical weaknesses in the application of evidence in decision-making, both locally and globally
Non-Steroidal Anti-Inflammatory Drugs for the Prevention of Colorectal Cancer
Medicine (16 obras) · Health Systems, Economic Evaluations, Quality of Life (12 obras) · Pathology (7 obras) · Political science (7 obras) · Public health (7 obras) · Health Policy Implementation Science (6 obras) · Internal Medicine (6 obras) · Psychology (6 obras) · Alternative medicine (5 obras) · Business (5 obras)