Cornelia M Van Duijn

Datos Biográficos

ID	1754419
NOMBRE	Cornelia M Van Duijn
NOMBRES	Cornelia M
APELLIDO	Van Duijn
FIRMA	VAN DUIJN C M
AFILIACIONES	Erasmus MC
ORCID	0000-0002-2374-9204
VERIFICADO	Sí
TOTAL DE OBRAS	14
TOTAL DE CITAS	35
OBRAS COMO AUTOR	14
OBRAS COMO EDITOR	0
PRIMER AÑO DE PUBLICACIÓN	2004
AÑO MÁS RECIENTE DE PUBLICACIÓN	2025
ÍNDICE H	2

U.S. public perceptions on whether risk of dementia and stroke can be modified through maintaining or changing lifestyle
Open AccessJasper R Senff, Mark Jun Shah-Ostrowski et al.ARTICLEBMC Public Health2025
This cross-sectional cohort, mimicking the general U.S. population, demonstrated that over 80% of individuals ever knew someone with dementia or stroke and that this was positively associated with the perceptions that dementia and stroke risk could be modified through lifestyle changes. The widespread exposure of the U.S. public to dementia and stroke first-hand can be leveraged into more effective preventive strategies
The genetic landscape of neuro-related proteins in human plasma
Open AccessLuca Repetto, Jiantao Chen et al.ARTICLENature Human Behaviour2024Referencias: 70
Does ethnicity influence dementia, stroke and mortality risk? Evidence from the UK Biobank
Open AccessBruno Bonnechère, Jun Liu et al.ARTICLEFrontiers in Public Health2023
Introduction: The number of people with dementia and stroke is increasing worldwide. There is increasing evidence that there are clinically relevant genetic differences across ethnicities. This study aims to quantify risk factors of dementia, stroke, and mortality in Asian and black participants compared to whites. Methods: = 2,358, 0.84%) participants. Cumulative incidence risk was calculated based on all incident cases occurring during the foll…
Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals
Open AccessAysu Okbay, Yeda Wu et al.ARTICLENature Genetics2022
We conduct a genome-wide association study (GWAS) of educational attainment (EA) in a sample of ~3 million individuals and identify 3,952 approximately uncorrelated genome-wide-significant single-nucleotide polymorphisms (SNPs). A genome-wide polygenic predictor, or polygenic index (PGI), explains 12–16% of EA variance and contributes to risk prediction for ten diseases. Direct effects (i.e., controlling for parental PGIs) explain roughly half th…
Identification of 371 genetic variants for age at first sex and birth linked to externalising behaviour
Open AccessMelinda C Mills, Felix C Tropf et al.ARTICLENature Human Behaviour2021Citada por: 10Referencias: 81
Genome-wide association study identifies 48 common genetic variants associated with handedness
Open AccessGabriel Cuellar-Partida, Joyce Y Tung et al.ARTICLENature Human Behaviour2020Citada por: 2Referencias: 68
Handedness has been extensively studied because of its relationship with language and the over-representation of left-handers in some neurodevelopmental disorders. Using data from the UK Biobank, 23andMe and the International Handedness Consortium, we conducted a genome-wide association meta-analysis of handedness (N = 1,766,671). We found 41 loci associated (P < 5 × 10−8) with left-handedness and 7 associated with ambidexterity. Tissue-enrichmen…
Bivariate Genome-Wide Association Study of Depressive Symptoms With Type 2 Diabetes and Quantitative Glycemic Traits
Kadri Haljas, Azmeraw T Amare et al.ARTICLEPsychosomatic Medicine2018
OBJECTIVE: Shared genetic background may explain phenotypic associations between depression and Type 2 diabetes (T2D). We aimed to study, on a genome-wide level, if genetic correlation and pleiotropic loci exist between depressive symptoms and T2D or glycemic traits. METHODS: We estimated single-nucleotide polymorphism (SNP)-based heritability and analyzed genetic correlation between depressive symptoms and T2D and glycemic traits with the linkag…
Genetic evidence of assortative mating in humans
Open AccessM R Robinson, Aaron Kleinman et al.ARTICLENature Human Behaviour2017Citada por: 23Referencias: 49
Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses
Open AccessLifelines Cohort Study, Aysu Okbay et al.ARTICLENature Genetics2016
Genome-wide association study identifies 74 loci associated with educational attainment
Open AccessAysu Okbay, Jonathan P Beauchamp et al.ARTICLENature2016
Genetic studies of body mass index yield new insights for obesity biology
Open AccessThe Lifelines Cohort Study, Adam E Locke et al.ARTICLENature2015
GWAS of 126,559 Individuals Identifies Genetic Variants Associated with Educational Attainment
Open AccessCornelius A Rietveld, Sarah E Medland et al.ARTICLEScience2013
Genetic College Many genomic elements in humans are associated with behavior, including educational attainment. In a genome-wide association study including more than 100,000 samples, Rietveld et al. (p. 1467 , published online 30 May; see the Perspective by Flint and Munafò ) looked for genes related to educational attainment in Caucasians. Small genetic effects at three loci appeared to impact educational attainment.
Human transmissible spongiform encephalopathies in eleven countries
Open AccessJesús de Pedro-Cuesta, Jesús de Pedro‐Cuesta et al.ARTICLEBMC Public Health2006
Considerable international variation in aetiological subtypes of human transmissible spongiform encephalopathies was evident over the observation period. With the exception of variant Creutzfeldt-Jakob disease and iatrogenic Creutzfeldt-Jakob disease in France and the United Kingdom, these differences persisted across time
Mild cognitive impairment – beyond controversies, towards a consensus
Open AccessBengt Winblad, Katie Palmer et al.ARTICLEJournal of Internal Medicine2004
The First Key Symposium was held in Stockholm, Sweden, 2–5 September 2003. The aim of the symposium was to integrate clinical and epidemiological perspectives on the topic of Mild Cognitive Impairment (MCI). A multidisciplinary, international group of experts discussed the current status and future directions of MCI, with regard to clinical presentation, cognitive and functional assessment, and the role of neuroimaging, biomarkers and genetics. A…

Mild cognitive impairment – beyond controversies, towards a consensus
Open AccessBengt Winblad, Katie Palmer et al.ARTICLEJournal of Internal Medicine2004
The First Key Symposium was held in Stockholm, Sweden, 2–5 September 2003. The aim of the symposium was to integrate clinical and epidemiological perspectives on the topic of Mild Cognitive Impairment (MCI). A multidisciplinary, international group of experts discussed the current status and future directions of MCI, with regard to clinical presentation, cognitive and functional assessment, and the role of neuroimaging, biomarkers and genetics. A…
Human transmissible spongiform encephalopathies in eleven countries
Open AccessJesús de Pedro-Cuesta, Jesús de Pedro‐Cuesta et al.ARTICLEBMC Public Health2006
Considerable international variation in aetiological subtypes of human transmissible spongiform encephalopathies was evident over the observation period. With the exception of variant Creutzfeldt-Jakob disease and iatrogenic Creutzfeldt-Jakob disease in France and the United Kingdom, these differences persisted across time
GWAS of 126,559 Individuals Identifies Genetic Variants Associated with Educational Attainment
Open AccessCornelius A Rietveld, Sarah E Medland et al.ARTICLEScience2013
Genetic College Many genomic elements in humans are associated with behavior, including educational attainment. In a genome-wide association study including more than 100,000 samples, Rietveld et al. (p. 1467 , published online 30 May; see the Perspective by Flint and Munafò ) looked for genes related to educational attainment in Caucasians. Small genetic effects at three loci appeared to impact educational attainment.
Genetic studies of body mass index yield new insights for obesity biology
Open AccessThe Lifelines Cohort Study, Adam E Locke et al.ARTICLENature2015
Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses
Open AccessLifelines Cohort Study, Aysu Okbay et al.ARTICLENature Genetics2016
Genome-wide association study identifies 74 loci associated with educational attainment
Open AccessAysu Okbay, Jonathan P Beauchamp et al.ARTICLENature2016
Genetic evidence of assortative mating in humans
Open AccessM R Robinson, Aaron Kleinman et al.ARTICLENature Human Behaviour2017Citada por: 23Referencias: 49
Bivariate Genome-Wide Association Study of Depressive Symptoms With Type 2 Diabetes and Quantitative Glycemic Traits
Kadri Haljas, Azmeraw T Amare et al.ARTICLEPsychosomatic Medicine2018
OBJECTIVE: Shared genetic background may explain phenotypic associations between depression and Type 2 diabetes (T2D). We aimed to study, on a genome-wide level, if genetic correlation and pleiotropic loci exist between depressive symptoms and T2D or glycemic traits. METHODS: We estimated single-nucleotide polymorphism (SNP)-based heritability and analyzed genetic correlation between depressive symptoms and T2D and glycemic traits with the linkag…
Genome-wide association study identifies 48 common genetic variants associated with handedness
Open AccessGabriel Cuellar-Partida, Joyce Y Tung et al.ARTICLENature Human Behaviour2020Citada por: 2Referencias: 68
Handedness has been extensively studied because of its relationship with language and the over-representation of left-handers in some neurodevelopmental disorders. Using data from the UK Biobank, 23andMe and the International Handedness Consortium, we conducted a genome-wide association meta-analysis of handedness (N = 1,766,671). We found 41 loci associated (P < 5 × 10−8) with left-handedness and 7 associated with ambidexterity. Tissue-enrichmen…
Identification of 371 genetic variants for age at first sex and birth linked to externalising behaviour
Open AccessMelinda C Mills, Felix C Tropf et al.ARTICLENature Human Behaviour2021Citada por: 10Referencias: 81
Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals
Open AccessAysu Okbay, Yeda Wu et al.ARTICLENature Genetics2022
We conduct a genome-wide association study (GWAS) of educational attainment (EA) in a sample of ~3 million individuals and identify 3,952 approximately uncorrelated genome-wide-significant single-nucleotide polymorphisms (SNPs). A genome-wide polygenic predictor, or polygenic index (PGI), explains 12–16% of EA variance and contributes to risk prediction for ten diseases. Direct effects (i.e., controlling for parental PGIs) explain roughly half th…
Does ethnicity influence dementia, stroke and mortality risk? Evidence from the UK Biobank
Open AccessBruno Bonnechère, Jun Liu et al.ARTICLEFrontiers in Public Health2023
Introduction: The number of people with dementia and stroke is increasing worldwide. There is increasing evidence that there are clinically relevant genetic differences across ethnicities. This study aims to quantify risk factors of dementia, stroke, and mortality in Asian and black participants compared to whites. Methods: = 2,358, 0.84%) participants. Cumulative incidence risk was calculated based on all incident cases occurring during the foll…
The genetic landscape of neuro-related proteins in human plasma
Open AccessLuca Repetto, Jiantao Chen et al.ARTICLENature Human Behaviour2024Referencias: 70
U.S. public perceptions on whether risk of dementia and stroke can be modified through maintaining or changing lifestyle
Open AccessJasper R Senff, Mark Jun Shah-Ostrowski et al.ARTICLEBMC Public Health2025
This cross-sectional cohort, mimicking the general U.S. population, demonstrated that over 80% of individuals ever knew someone with dementia or stroke and that this was positively associated with the perceptions that dementia and stroke risk could be modified through lifestyle changes. The widespread exposure of the U.S. public to dementia and stroke first-hand can be leveraged into more effective preventive strategies