Marie Zins
Datos Biográficos
| ID | 2162242 |
|---|---|
| NOMBRE | Marie Zins |
| NOMBRES | Marie |
| APELLIDO | Zins |
| FIRMA | ZINS M |
| AFILIACIONES | Inserm |
| ORCID | 0000-0002-4540-4282 |
| VERIFICADO | Sí |
| TOTAL DE OBRAS | 51 |
| TOTAL DE CITAS | 106 |
| TOTAL COMO AUTOR | 51 |
| TOTAL COMO EDITOR | 0 |
| PRIMER AÑO DE PUBLICACIÓN | 2003 |
| AÑO MÁS RECIENTE DE PUBLICACIÓN | 2026 |
| ÍNDICE H | 4 |
Intergenerational Social Mobility and Smoking Trajectories in Middle-Aged Adults – The French Constances Cohort Study (2012–2020)
INTRODUCTION: Tobacco smoking remains a public health challenge, particularly among low-income populations. Beyond individuals' own socioeconomic position, their family background and the type of social trajectory they experienced, could also be related to smoking behaviors as tobacco use starts generally in adolescence. In the present study, we tested the association between intergenerational social mobility and individuals' smoking trajectories…
Co-Trajectories of Substance Use and Work Status
OBJECTIVE: We aimed to identify substance use and work status co-trajectories and to describe the sociodemographic and clinical characteristics of each profile. METHODS: From the French CONSTANCES cohort, 19,285 adults enrolled between 2012 and 2015, were included in the analyses. Clusters of co-trajectories of substance use (alcohol, tobacco and cannabis) and work status at baseline and 5-years period of follow-up were identified using finite mi…
Non-linear relationships between lifetime unemployment exposure, major health outcomes and all-cause mortality
The non-linear relationships of lifetime unemployment exposure with cardiovascular disease and all-cause mortality rates may be related to the health benefits of having the occasional opportunity to leave jobs with bad working conditions over the life course
Worldwide trends in underweight and obesity from 1990 to 2022
BACKGROUND: Underweight and obesity are associated with adverse health outcomes throughout the life course. We estimated the individual and combined prevalence of underweight or thinness and obesity, and their changes, from 1990 to 2022 for adults and school-aged children and adolescents in 200 countries and territories. METHODS: ). For school-aged children and adolescents, we report thinness (BMI 2 SD above the median). FINDINGS: From 1990 to 20…
Use of Mobile Phones and Radiofrequency-Emitting Devices in the Cosmos-France Cohort
In this cross-sectional presentation of contemporary mobile phone usage in France, age and sex were important determinants of use patterns
Changes in household use of disinfectant and cleaning products during the first lockdown period in France
The frequency and duration of weekly use of HDCPs has significantly increased since the pandemic. As the use of HDCPs is associated with health issues, further studies are now needed to evaluate the potential health impacts of these changes
Lifetime exposure to unemployment and prior working conditions are associated with retiree's health
Cannabis Use Increases the Risk of Sickness Absence
Aims To examine the longitudinal associations between cannabis use and risks of short ( 28 days) sickness absences at one-year follow-up. Methods 87,273 participants aged 18-65 years from the French CONSTANCES cohort reported their frequency of cannabis use at inclusion between 2012 and 2018. Sickness absences occurring during one year of follow-up were collected from national medico-administrative registries. Multivariable generalized linear reg…
Teachers’ Health
Teachers' health is a key factor of any successful education system, but available data are conflicting. To evaluate to what extent teachers' health could be at risk, we used pre-pandemic data from the CONSTANCES population-based French cohort (inclusion phase: 2012-2019) and compared teachers (n = 12,839) included in the cohort with a random subsample selected among all other employees (n = 32,837) on four self-reported health indicators: percei…
Atypical working hours are associated with tobacco, cannabis and alcohol use
The potential role of atypical working hours on substance use should be considered by public health policy makers and clinicians in information and prevention strategies
Changing eating practices after midlife
Understanding not only differences in consumption but differences in how consumption changes presents a theoretical and empirical challenge. In this article, we draw on theories of practice, a life-course perspective and approaches in terms of tastes or dispositions to examine how food consumption changed after midlife in a large cohort of French adults aged from 50 to 75 years. We have been able to present a bird’s eye view of these practices, t…
Association between positive psychological traits and changes in dietary behaviour related to first Covid-19 lockdown
Adverse employment histories and allostatic load
BACKGROUND: Most studies on the health impact of occupational stress use single-point measures of stress at work. This study analyses the associations of properties of entire employment trajectories over an extended time period with a composite score of allostatic load (AL). METHODS: Data come from the French CONSTANCES cohort, with information on adverse employment histories between ages 25 and 45 and a composite score of AL (based on 10 biomark…
Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019
BACKGROUND: Hypertension can be detected at the primary health-care level and low-cost treatments can effectively control hypertension. We aimed to measure the prevalence of hypertension and progress in its detection, treatment, and control from 1990 to 2019 for 200 countries and territories. METHODS: We used data from 1990 to 2019 on people aged 30-79 years from population-representative studies with measurement of blood pressure and data on blo…
Antibody status and cumulative incidence of Sars-CoV-2 infection among adults in three regions of France following the first lockdown and associated risk factors
BACKGROUND: We aimed to estimate the seropositivity to anti-SARS-CoV-2 antibodies in May-June 2020 after the first lockdown period in adults living in three regions in France and to identify the associated risk factors. METHODS: Between 4 May 2020 and 23 June 2020, 16 000 participants in a survey on COVID-19 from an existing consortium of three general adult population cohorts living in the Ile-de-France (IDF) or Grand Est (GE) (two regions with …
Occupational Exposures to Organic Solvents and Asthma Symptoms in the Constances Cohort
Solvents are used in many workplaces and may be airway irritants but few studies have examined their association with asthma. We studied this question in CONSTANCES (cohort of 'CONSulTANts des Centres d'Examens de Santé'), a large French cohort. Current asthma and asthma symptom scores were defined by participant-reported respiratory symptoms, asthma medication or attacks, and the sum of 5 symptoms, in the past 12 months, respectively. Lifetime e…
Correlates of premature pap test screening, under 25 years old
Young women using contraceptives that require a doctor's prescription are exposed to premature screening more often than those not using contraception and those with nonmedicalized contraceptives
When lockdown policies amplify social inequalities in Covid-19 infections
Lockdown was associated with social inequalities in the decline in COVID-19 infections, calling for the adoption of preventive policies to account for living and working conditions. Such adoptions are critical to reduce social inequalities related to COVID-19, as working-class individuals also have the highest COVID-19 related mortality, due to higher prevalence of comorbidities
The Constances Cohort Biobank
“General-purpose cohorts” in epidemiology and public health are designed to cover a broad scope of determinants and outcomes, in order to answer several research questions, including those not defined at study inception. In this context, the general objective of the CONSTANCES project is to set up a large population-based cohort that will contribute to the development of epidemiological research by hosting ancillary projects on a wide range of sc…
Special Report
Funded by the European Commission Horizon2020 programme, the Lifepath research consortium aimed to understand the impacts of socioeconomic inequalities on the biology of healthy ageing. The main research questions included the impact of inequalities on health, the role of behavioural and other risk factors, the underlying biological mechanisms, the efficacy of selected policies, and the general implications of our findings for theories and polici…
Bien vieillir, bien manger
Les politiques publiques de prévention du vieillissement incitent à bien manger pour « bien vieillir » mais ces recommandations sont en concurrence avec d’autres registres normatifs. Le rapport aux normes nutritionnelles étant socialement différencié, cet article étudie l’évolution de l’alimentation au fil de l’avancée en âge pour les hommes et les femmes dans la cohorte prospective française Gazel. Ils sont suivis de 45 à 75 ans soit aux âges vi…
Diet and physical activity in the association between depression and metabolic syndrome
Intragenerational Social Mobility and Depressive Symptoms. Results From the French Constances Cohort Study
Our findings underline the importance of integrating data into analysis on starting and ending points of social mobility processes within entire histories of labor market participation
Prevalence of prescribed benzodiazepine long-term use in the French general population according to sociodemographic and clinical factors
BLTU is widespread in the French general population, however this issue may particularly concern vulnerable subgroups. These findings may help in raising attention on this public health burden as well as targeting specific at-risk subgroups in preventive intervention
Poverty does not modify the association between perceived diet healthiness and adherence to nutritional guidelines in the Constances cohort (France)
What does self rated health measure? Results from the British Whitehall II and French Gazel cohort studies
Objectives: To investigate the determinants of self rated health (SRH) in men and women in the British Whitehall II study and the French Gazel cohort study. Methods: The cross sectional analyses reported in this paper use data from wave 1 of the Whitehall II study (1985–88) and wave 2 of the Gazel study (1990). Determinants were either self reported or obtained through medical screening and employer’s records. The Whitehall II study is based on 2…
Lifelong socioeconomic trajectory and premature mortality (35–65 years) in France
Background: Studies conducted in the UK and Scandinavia show an inverse association between lifetime socioeconomic position and adult mortality. However, there are virtually no data from other countries and few investigations have examined non-cardiovascular mortality in men and women. Methods: Lifelong socioeconomic trajectories (father’s occupation, own occupation in young adulthood and in mid-life) and premature (⩽65 years) mortality (all-caus…
Informal Caregiving and Self-Reported Mental and Physical Health
Objectives. We investigated whether, and under what conditions, informal caregiving is associated with improved self-reported physical and mental health, most notably in terms of cognitive functioning. Methods. We performed a cross-sectional analysis of 2008 data from the Gazel Cohort Study, which involved 10 687 men and women aged 54 to 70 years. Multivariate linear and logistic regression models were used to estimate the associations between se…
Job Strain and Health-Related Lifestyle
Objectives. We examined the associations of job strain, an indicator of work-related stress, with overall unhealthy and healthy lifestyles. Methods. We conducted a meta-analysis of individual-level data from 11 European studies (cross-sectional data: n = 118 701; longitudinal data: n = 43 971). We analyzed job strain as a set of binary (job strain vs no job strain) and categorical (high job strain, active job, passive job, and low job strain) var…
Do different measures of early life socioeconomic circumstances predict adult mortality? Evidence from the British Whitehall II and French Gazel studies
BACKGROUND: Father's occupational position, education and height have all been used to examine the effects of adverse early life socioeconomic circumstances on health, but it remains unknown whether they predict mortality equally well. METHODS: We used pooled data on 18,393 men and 7060 women from the Whitehall II and GAZEL cohorts to examine associations between early life socioeconomic circumstances and all-cause and cause-specific mortality. R…
Changing eating practices after midlife
Understanding not only differences in consumption but differences in how consumption changes presents a theoretical and empirical challenge. In this article, we draw on theories of practice, a life-course perspective and approaches in terms of tastes or dispositions to examine how food consumption changed after midlife in a large cohort of French adults aged from 50 to 75 years. We have been able to present a bird’s eye view of these practices, t…
Long-term effects of compulsory schooling on physical, mental and cognitive ageing
BACKGROUND: Longer schooling is associated with better physical, mental and cognitive functioning, but there is controversy as to whether these associations are causal. We examine the long-term health impact of a policy that increased compulsory schooling by 2 years in France for cohorts born on or after January 1953, offering a natural experiment. METHODS: Data came from Constances, a randomly selected cohort of the French population assessed fo…
Longer schooling but not better off? A quasi-experimental study of the effect of compulsory schooling on biomarkers in France
Less schooling is associated with increased biological risks for chronic disease, but whether increasing years of schooling through policy interventions reduces these risks remains unclear. We examine the effect of a major education reform introduced in 1959 that raised the minimum school leaving age from 14 to 16 years in France, offering a unique natural experiment. We assess the causal impact of increased schooling duration on 16 biomarkers of…
Work environment mediates a large part of social inequalities in the incidence of several common cardiovascular risk factors
Adverse employment histories and allostatic load
BACKGROUND: Most studies on the health impact of occupational stress use single-point measures of stress at work. This study analyses the associations of properties of entire employment trajectories over an extended time period with a composite score of allostatic load (AL). METHODS: Data come from the French CONSTANCES cohort, with information on adverse employment histories between ages 25 and 45 and a composite score of AL (based on 10 biomark…
Poverty does not modify the association between perceived diet healthiness and adherence to nutritional guidelines in the Constances cohort (France)
Long working hours, anthropometry, lung function, blood pressure and blood-based biomarkers
BACKGROUND: Although long working hours have been shown to be associated with the onset of cardiometabolic diseases, the clinical risk factor profile associated with long working hours remains unclear. We compared the clinical risk profile between people who worked long hours and those who reported being never exposed to long hours. METHODS: A cross-sectional study in 22 health screening centres in France was based on a random population-based sa…
Work-Related Stressors and Increased Risk of Benzodiazepine Long-Term Use
Objectives. To examine whether stressful job exposure to the public could be associated with having long-term benzodiazepine use. Methods. From the participants included between 2012 and 2016 in the French population-based CONSTANCES cohort, 13 934 men and 19 261 women declared a daily job exposure to the public and rated the frequency of stressful exposure. We examined benzodiazepine long-term use by using drug reimbursement administrative regis…
Diagnosis-specific sick leave as a long-term predictor of disability pension
BACKGROUND: Factors that increase the risk of labour market exclusion are poorly understood. In this study, we examined the extent to which all-cause and diagnosis-specific sick leave predict subsequent disability pension (DP). METHODS: Prospective cohort study of 20 434 persons employed by the French national gas and electric company (the GAZEL study). New sick-leave spells >7 days in 1990-1992 were obtained from company records. Follow-up for D…
Investigating the spatial variability in incidence of coronary heart disease in the Gazel Cohort
STUDY OBJECTIVE: The aim of the study was to improve understanding of the relationships between contextual socioeconomic characteristics and coronary heart disease (CHD) incidence in France. Several authors have suggested that CHD risk factors (diabetes, hypertension, cholesterol, overweight, tobacco consumption) may partly mediate associations between socioeconomic environmental variables and CHD. Studies have assessed the overall mediating role…
All-cause and diagnosis-specific sickness absence as a predictor of sustained suboptimal health
UNLABELLED: background: Previous studies show that sickness absence predicts health, but it is unclear whether this association is persistent over time and whether specific diseases underlie long-term associations. The aim of this study was to investigate overall and diagnosis-specific sickness absences as predictors of sustained suboptimal health. METHODS: Prospective occupational cohort study of 15 320 employees (73% men) aged 37-51. Sickness a…
Place du passage à la retraite parmi les déterminants socioprofessionnels de la consommation de boissons alcoolisées des volontaires de la Cohorte Gazel
Les objectifs de cette etude sont de decrire l'evolution de la consommation de boissons alcoolisees des participants hommes et femmes d'une cohorte definie par l'INSERM pendant la periode 1992-1998 en fonction de leur statut socio-professionnel, et d'etudier les eventuelles modifications de la consommation d'alcool observees dans la periode entourant le passage a la retraite. Ce travail essentiellement descriptif est destine a observer si cet eve…
Handedness and reproductive success in two large cohorts of French adults
Lifelong socioeconomic trajectory and premature mortality (35–65 years) in France
Background: Studies conducted in the UK and Scandinavia show an inverse association between lifetime socioeconomic position and adult mortality. However, there are virtually no data from other countries and few investigations have examined non-cardiovascular mortality in men and women. Methods: Lifelong socioeconomic trajectories (father’s occupation, own occupation in young adulthood and in mid-life) and premature (⩽65 years) mortality (all-caus…
What does self rated health measure? Results from the British Whitehall II and French Gazel cohort studies
Objectives: To investigate the determinants of self rated health (SRH) in men and women in the British Whitehall II study and the French Gazel cohort study. Methods: The cross sectional analyses reported in this paper use data from wave 1 of the Whitehall II study (1985–88) and wave 2 of the Gazel study (1990). Determinants were either self reported or obtained through medical screening and employer’s records. The Whitehall II study is based on 2…
Socio‐economic status and handedness in two large cohorts of French adults
Left‐and right‐handers have coexisted since the Palaeolithic age. Hand preference is heritable. Moreover, there is extensive evidence of an association between left‐handedness and several fitness costs. In this context, the persistence of the polymorphism is interesting. Here, we explore the associations between socio‐economic status and handedness, analysing data from two large cohorts of adult men and women. Such associations are relevant to an…
Self-rated health before and after retirement in France (Gazel)
Using Sickness Absence Records to Predict Future Depression in a Working Population
Objectives. We tested the hypothesis that sickness absence from work predicts workers' risk of later depression. Methods. Study participants (n = 7391) belonged to the French GAZEL cohort of employees of the national gas and electricity company. Sickness absence data (1996–1999) were obtained from company records. Participants' depression in 1996 and 1999 was assessed with the Center for Epidemiologic Studies–Depression (CES-D) scale. The analyse…
The Constances Cohort
The constitution of the full eligible sample is planned during the last trimester of 2010, and the cohort will be launched at the beginning of 2011
All-cause and diagnosis-specific sickness absence as a predictor of sustained suboptimal health
UNLABELLED: background: Previous studies show that sickness absence predicts health, but it is unclear whether this association is persistent over time and whether specific diseases underlie long-term associations. The aim of this study was to investigate overall and diagnosis-specific sickness absences as predictors of sustained suboptimal health. METHODS: Prospective occupational cohort study of 15 320 employees (73% men) aged 37-51. Sickness a…
Health Behaviours, Socioeconomic Status, and Mortality
BACKGROUND: Differences in morbidity and mortality between socioeconomic groups constitute one of the most consistent findings of epidemiologic research. However, research on social inequalities in health has yet to provide a comprehensive understanding of the mechanisms underlying this association. In recent analysis, we showed health behaviours, assessed longitudinally over the follow-up, to explain a major proportion of the association of soci…
Investigating the spatial variability in incidence of coronary heart disease in the Gazel Cohort
STUDY OBJECTIVE: The aim of the study was to improve understanding of the relationships between contextual socioeconomic characteristics and coronary heart disease (CHD) incidence in France. Several authors have suggested that CHD risk factors (diabetes, hypertension, cholesterol, overweight, tobacco consumption) may partly mediate associations between socioeconomic environmental variables and CHD. Studies have assessed the overall mediating role…
Do different measures of early life socioeconomic circumstances predict adult mortality? Evidence from the British Whitehall II and French Gazel studies
BACKGROUND: Father's occupational position, education and height have all been used to examine the effects of adverse early life socioeconomic circumstances on health, but it remains unknown whether they predict mortality equally well. METHODS: We used pooled data on 18,393 men and 7060 women from the Whitehall II and GAZEL cohorts to examine associations between early life socioeconomic circumstances and all-cause and cause-specific mortality. R…
Informal Caregiving and Self-Reported Mental and Physical Health
Objectives. We investigated whether, and under what conditions, informal caregiving is associated with improved self-reported physical and mental health, most notably in terms of cognitive functioning. Methods. We performed a cross-sectional analysis of 2008 data from the Gazel Cohort Study, which involved 10 687 men and women aged 54 to 70 years. Multivariate linear and logistic regression models were used to estimate the associations between se…
Job strain as a risk factor for coronary heart disease
Diagnosis-specific sick leave as a long-term predictor of disability pension
BACKGROUND: Factors that increase the risk of labour market exclusion are poorly understood. In this study, we examined the extent to which all-cause and diagnosis-specific sick leave predict subsequent disability pension (DP). METHODS: Prospective cohort study of 20 434 persons employed by the French national gas and electric company (the GAZEL study). New sick-leave spells >7 days in 1990-1992 were obtained from company records. Follow-up for D…
Personality and the Risk of Cancer
OBJECTIVE: Large-scale prospective studies do not support an association between neuroticism and extroversion with cancer incidence. However, research on other personality constructs is inconclusive. This longitudinal study examined the associations between four personality measures, Type 1, "suppressed emotional expression"; Type 5, "rational/antiemotional"; hostility; and Type A with cancer incidence. METHODS: Personality measures were availabl…
Job Strain and Health-Related Lifestyle
Objectives. We examined the associations of job strain, an indicator of work-related stress, with overall unhealthy and healthy lifestyles. Methods. We conducted a meta-analysis of individual-level data from 11 European studies (cross-sectional data: n = 118 701; longitudinal data: n = 43 971). We analyzed job strain as a set of binary (job strain vs no job strain) and categorical (high job strain, active job, passive job, and low job strain) var…
High quality standards for a large-scale prospective population-based observational cohort
Despite Constances volunteers being followed in multiple sites with heterogeneous materials, the investment of significant resources to set up and maintain a continuous quality management process has proved effective in preventing drifts and improving accuracy of collected data
Socioeconomic gradient in work disability in diabetes
BACKGROUND: The role of socioeconomic status in work disability among employees with diabetes is not well known. We examined the association between socioeconomic status and work disability among employees with and without diabetes taking into account comorbid conditions. METHODS: We used individual participant data from three occupational cohorts from Finland, France and the UK (employees with diabetes, n=2170, age-matched and sex-matched contro…
Socioeconomic status and the 25 × 25 risk factors as determinants of premature mortality
Work environment mediates a large part of social inequalities in the incidence of several common cardiovascular risk factors
Diet and physical activity in the association between depression and metabolic syndrome
Intragenerational Social Mobility and Depressive Symptoms. Results From the French Constances Cohort Study
Our findings underline the importance of integrating data into analysis on starting and ending points of social mobility processes within entire histories of labor market participation
Prevalence of prescribed benzodiazepine long-term use in the French general population according to sociodemographic and clinical factors
BLTU is widespread in the French general population, however this issue may particularly concern vulnerable subgroups. These findings may help in raising attention on this public health burden as well as targeting specific at-risk subgroups in preventive intervention
Poverty does not modify the association between perceived diet healthiness and adherence to nutritional guidelines in the Constances cohort (France)
Medicine (41 obras) · Cohort (30 obras) · Population (29 obras) · Cohort study (28 obras) · Environmental health (28 obras) · Demography (27 obras) · Internal Medicine (23 obras) · Gerontology (17 obras) · Workplace Health and Well-being (15 obras) · Employment and Welfare Studies (13 obras)