Valériane Leroy
Datos Biográficos
| ID | 281253 |
|---|---|
| NOMBRE | Valériane Leroy |
| NOMBRES | Valériane |
| APELLIDO | Leroy |
| FIRMA | LEROY V |
| AFILIACIONES | Inserm |
| ORCID | 0000-0003-3542-8616 |
| VERIFICADO | Sí |
| TOTAL DE OBRAS | 30 |
| TOTAL DE CITAS | 16 |
| TOTAL COMO AUTOR | 30 |
| TOTAL COMO EDITOR | 0 |
| PRIMER AÑO DE PUBLICACIÓN | 1996 |
| AÑO MÁS RECIENTE DE PUBLICACIÓN | 2026 |
| ÍNDICE H | 2 |
Added value of routine pulse oximetry use within Integrated Management of Childhood Illness guidelines in primary care in West Africa
BACKGROUND: <90%), a predictor of mortality in children under five. The AIRE (Améliorer l'Identification des Détresses Respiratoires chez l'Enfant; in English, Improving Identification of Respiratory Distress in Children) operational research project introduced routine use of pulse oximetry (PO) within IMCI consultations in Burkina Faso, Guinea, Mali and Niger. We estimated the added value of incorporating PO within IMCI (IMCI+PO) for improving t…
Living in Fear
Dedicated studies to understand and explore HIV-related stigma among PWH in Senegal are essential for the development and implementation of effective stigma reduction strategies. The goals of this study were to understand the current challenges confronted by newly diagnosed PWH in Senegal and to explore the manifestations of HIV-related stigma using a mixed methods approach. We conducted a convergent mixed methods study among participants ≥ 18 ye…
Under the Influence
Alcohol and substance use in youth living with HIV (YLHIV) can influence health and treatment outcomes. We assessed substance use and associations with antiretroviral therapy (ART) adherence among YLHIV. The Adolescent and Young Adult Network of IeDEA enrolled YLHIV (15–24 years old) receiving ART (2021–2024) from 6 global regions. We assessed biopsychosocial experiences with validated tools; adherence with self-reported missed medication doses a…
Assessing the effects of the Covid-19 pandemic on new ART initiation and viral load access among children and adolescents living with HIV in West Africa
Background: Before the COVID-19 pandemic, the pediatric continuum of HIV care lagged behind that of adults. The present study aimed to describe the effects of the COVID-19 pandemic on access to HIV care among children and adolescents (0-19 years) living with HIV (CALHIV) in five West African countries. Methods: Within this observational multicenter study, we conducted an interrupted time series analysis by including all antiretroviral therapy (AR…
Prevalence and factors associated with severe illness in West African children under 5 years of age detected with routine pulse oximetry in primary care
BACKGROUND: The Integrated Management of Childhood Illness (IMCI) guidelines are symptom-based algorithms used to identify critically ill children under five in primary health centres (PHC) in resource-limited countries. Hypoxaemia, a life-threatening event, is clinically underdiagnosed. The Amélioration de l'Identification des détresses Respiratoires de l'Enfant/Improving Identification of Respiratory Distress in Children (AIRE) project implemen…
Missed opportunities for hospital referral of young children with severe pneumonia identified at primary care using pulse oximetry
Background In line with the Integrated Management of Childhood Illness (IMCI) guidelines, healthcare workers (HCWs) should refer all severe pneumonia among children under 5 seen in primary care in resource-limited settings. We investigated the frequency and correlates of missed opportunities for hospital referral (MOHR) of clinical severe pneumonia. Our study was embedded within the Améliorer l'Identification des détresses Respiratoires chez l'En…
Disparities in dolutegravir utilisation in children, adolescents and young adults (0–24 years) living with HIV. An analysis of the IeDEA Pediatric West African cohort
INTRODUCTION: We describe the 24-month incidence of Dolutegravir (DTG)-containing antiretroviral treatment (ART) initiation since its introduction in 2019 in West Africa. METHODS: We included all patients aged 0-24 years on ART from nine clinics in Côte d'Ivoire (n=4), Ghana, Nigeria, Mali, Benin, and Burkina Faso. Baseline varied by clinic and was defined as date of first DTG prescription; patients were followed up until database closure/death/l…
Care management and determinants of day 14 mortality in severely ill children aged under 5 years subsequent to hypoxaemia diagnosed using routine pulse oximetry in primary care
BACKGROUND: The Amélioration de l'Identification des détresses Respiratoires de l'Enfant (AIRE) project introduced the routine use of pulse oximetry (PO) into Integrated Management of Childhood Illness (IMCI) consultations within primary health centres (PHCs) in Burkina Faso, Guinea, Mali and Niger. We analysed how severe cases were managed and 14-day mortality by hypoxaemia severity. METHODS: <90%) were eligible for referral and enrolled in a 14…
Understanding health innovation adoption
INTRODUCTION: Hypoxaemia is an important contributor to child mortality, particularly in low-resource settings where diagnostic tools are scarce. The Améliorer l'Identification des détresses Respiratoires chez l'Enfant project introduced pulse oximeters (POs) into 202 primary healthcare centres (PHCs) in Burkina Faso, Guinea, Mali and Niger, integrating them into the Integrated Management of Childhood Illness guidelines. This initiative aimed to …
Acceptability of the routine use of pulse oximetry by healthcare workers and caregivers within primary healthcare in West Africa
INTRODUCTION: To better identify severe hypoxaemia as a major risk factor for specific illnesses in children aged under 5 years, the Améliorer l'Identification des détresses Respiratoires chez l'Enfant (AIRE) project implemented routine use of pulse oximetry within implementation of Integrated Management of Childhood Illness (IMCI) guidelines at primary health centres (PHCs) in Burkina Faso, Guinea, Mali and Niger. We aimed to measure and underst…
Household costs of care in children under five attending primary care in Burkina Faso, Guinea, Mali and Niger
INTRODUCTION: Out-of-pocket payments limit access to care in Africa. The Amélioration de l'Identification des détresses Respiratoires de l'Enfant/Improving Identification of Respiratory Distress in Children (AIRE) project evaluated the implementation of pulse oximetry within Integrated Management of Childhood Illness (IMCI) guidelines at primary health centres (PHCs) in Burkina Faso and Niger (with total exemption policies) and in Mali and Guinea…
Challenges and needs before implementing routine pulse oximetry within primary care for sick children in West Africa
BACKGROUND: The Integrated Management of Childhood Illness (IMCI) guidelines are implemented within primary health centres (PHCs) in resource-limited settings. These symptom-based algorithms under-diagnose severe hypoxemia, which contributes to the under-five'mortality in sub-Saharan Africa. To improve the diagnosis and management of severe hypoxaemia, the Améliorer l'Identification des détresses Respiratoires chez l'Enfant (AIRE) project impleme…
Perceptions and management of diabetes and obesity among people living with HIV in Côte d’Ivoire
These results highlight the complexity surrounding the perceptions and management of T2DM and obesity among PLHIV in Abidjan, Côte d'Ivoire. In order to implement innovative and efficient intervention strategies to prevent and treat these metabolic conditions, cultural beliefs as well as socio-economic barriers must be addressed
Care pathways for critically ill children aged 0–5 years arriving at district hospitals in Burkina Faso, Guinea, Mali, and Niger (2022)
The recommended pathway is largely adhered to, yet parallel pathways require attention, notably in Guinea and Mali. A better understanding of healthcare-seeking behaviours can help remove barriers to care, improving the likelihood that a sick child will receive optimal care
Incidence of unintended pregnancies and pregnancy experience among adolescents living with perinatally-acquired HIV in West Africa
Registered with the Pan African Clinical Trials Registry on 13 February 2024 (reference no. PACTR202402863175053)
Évaluation quantitative de l’effet sur le passage aux urgences et les hospitalisations d’un dispositif départemental innovant de prise en charge des situations de crise durant l’adolescence en Haute-G…
Adolescent nutrition and physical activity in low-income suburbs of Abidjan, Côte d’lvoire
Objective: To explore adolescents’ perceptions, knowledge and behaviours regarding nutrition and physical activity in low-income districts of Abidjan, Côte d’Ivoire, taking into consideration their caregivers’ perspectives. Design: Two investigators conducted six focus group discussions. Setting: The study was carried out in two low-income suburbs, Yopougon and Port-Bouët, in Abidjan, Côte d’Ivoire. Participants: Adolescents and their caregivers …
How do we improve adolescent diet and physical activity in India and sub-Saharan Africa? Findings from the Transforming Adolescent Lives through Nutrition (Talent) consortium
Objective: Adolescent diet, physical activity and nutritional status are generally known to be sub-optimal. This is an introduction to a special issue of papers devoted to exploring factors affecting diet and physical activity in adolescents, including food insecure and vulnerable groups. Setting Eight settings including urban, peri-urban and rural across sites from five different low- and middle-income countries. Design: Focus groups with adoles…
A scoping review of literature describing the nutritional status and diets of adolescents in Côte d’Ivoire
Objective: Adolescents living in resource-limited settings remain a neglected population regarding their nutritional health. We reviewed what studies on nutrition have been conducted for adolescents living in Côte d’Ivoire. Design: A scoping literature review, searching for any quantitative studies published from 1 January 2000 to 1 May 2019, referenced in PubMed and grey literature, related to adolescent nutritional status and diet, written in E…
Pregnancy incidence and associated factors among HIV-infected female adolescents in HIV care in urban Côte d'Ivoire, 2009–2013
OBJECTIVE: Adolescents living with HIV are sexually active and engaged in risky sexual behaviors. Knowledge on how and to what extent adolescents in HIV care are affected by pregnancy is needed so as to adopt better preventive services. We estimated 4-year pregnancy incidence and correlates among HIV-infected female adolescents in HIV care in urban Côte d'Ivoire. DESIGN: We conducted retrospective analysis of a pediatric prospective cohort of the…
Intimate partner sexual and physical violence among women in Togo, West Africa
BACKGROUND: A substantial proportion of newly diagnosed HIV infections in sub-Saharan Africa occur within serodiscordant cohabiting heterosexual couples. Intimate partner violence is a major concern for couple-oriented HIV preventive approaches. This study aimed at estimating the prevalence and associated factors of intimate partner physical and sexual violence among HIV-infected and -uninfected women in Togo. We also described the severity and c…
Acceptabilité du test VIH proposé aux nourrissons dans les services pédiatriques, en Côte d'Ivoire,Significations pour la couverture du diagnostic pédiatrique
PROBLEM: HIV testing in children had rarely been a central concern for researchers. When pediatric tracking retained the attention, it was more to inform on the diagnosis tools' performances rather than the fact the pediatric test can be accepted or refused. This article highlights the parents' reasons which explain why pediatric HIV test is accepted or refused. OBJECTIVE: To study among parents, the explanatory factors of the acceptability of pe…
Month Mortality and Loss-to-Program in Antiretroviral-Treated Children
Innovative and sustainable approaches are needed to better document causes of death and increase retention in HIV pediatric clinics in West Africa
From prenatal HIV testing of the mother to prevention of sexual HIV transmission within the couple
Couples, PMTCT programs and infant feeding decision-making in Ivory Coast
A Cohort Study of Factors Associated with Failure to Return for HIV Post- test Counselling in Pregnant Women
Zidovudine and reduction of vertical transmission of HIV in Africa. ANRS 049 Trial Group
treatments (including chemotherapy)6 and indicators of overall quality ofhealth care by hospital service area. There is growing inter- est in regional variation in factors affecting the survival of cancer patients, including urban-rural differences in access to "highquality hospitals
Beneficial Effects of Offering Prenatal HIV Counselling and Testing on Developing a HIV Preventive Attitude among Couples. Abidjan, 2002–2005
Sexual prevention of HIV within the couple after prenatal HIV-testing in West Africa
The resumption of sexual activity after delivery is a key moment in the management of the risk of sexual HIV transmission within the couple for women who have been prenatally tested for HIV. In this study, we have investigated consistent condom use during the resumption of sexual activity and its evolution over time among women tested for HIV infection during pregnancy. We tested for HIV during pregnancy 546 HIV-infected and 393 HIV-negative wome…
Month occurrence of severe events among early diagnosed HIV-infected children before antiretroviral therapy in Abidjan, Côte d'Ivoire
Early cotrimoxazole from 6 weeks of age in HIV-infected infants seemed to reduce probability of severe events but the study lacked statistical power to prove this. Even with systematic cotrimoxazole prophylaxis, infant morbidity and mortality remained high pointing towards a need for early pediatric HIV-diagnosis and antiretroviral treatment in Africa
From prenatal HIV testing of the mother to prevention of sexual HIV transmission within the couple
Couples, PMTCT programs and infant feeding decision-making in Ivory Coast
Month Mortality and Loss-to-Program in Antiretroviral-Treated Children
Innovative and sustainable approaches are needed to better document causes of death and increase retention in HIV pediatric clinics in West Africa
Intimate partner sexual and physical violence among women in Togo, West Africa
BACKGROUND: A substantial proportion of newly diagnosed HIV infections in sub-Saharan Africa occur within serodiscordant cohabiting heterosexual couples. Intimate partner violence is a major concern for couple-oriented HIV preventive approaches. This study aimed at estimating the prevalence and associated factors of intimate partner physical and sexual violence among HIV-infected and -uninfected women in Togo. We also described the severity and c…
Acceptabilité du test VIH proposé aux nourrissons dans les services pédiatriques, en Côte d'Ivoire,Significations pour la couverture du diagnostic pédiatrique
PROBLEM: HIV testing in children had rarely been a central concern for researchers. When pediatric tracking retained the attention, it was more to inform on the diagnosis tools' performances rather than the fact the pediatric test can be accepted or refused. This article highlights the parents' reasons which explain why pediatric HIV test is accepted or refused. OBJECTIVE: To study among parents, the explanatory factors of the acceptability of pe…
Pregnancy incidence and associated factors among HIV-infected female adolescents in HIV care in urban Côte d'Ivoire, 2009–2013
OBJECTIVE: Adolescents living with HIV are sexually active and engaged in risky sexual behaviors. Knowledge on how and to what extent adolescents in HIV care are affected by pregnancy is needed so as to adopt better preventive services. We estimated 4-year pregnancy incidence and correlates among HIV-infected female adolescents in HIV care in urban Côte d'Ivoire. DESIGN: We conducted retrospective analysis of a pediatric prospective cohort of the…
Adolescent nutrition and physical activity in low-income suburbs of Abidjan, Côte d’lvoire
Objective: To explore adolescents’ perceptions, knowledge and behaviours regarding nutrition and physical activity in low-income districts of Abidjan, Côte d’Ivoire, taking into consideration their caregivers’ perspectives. Design: Two investigators conducted six focus group discussions. Setting: The study was carried out in two low-income suburbs, Yopougon and Port-Bouët, in Abidjan, Côte d’Ivoire. Participants: Adolescents and their caregivers …
How do we improve adolescent diet and physical activity in India and sub-Saharan Africa? Findings from the Transforming Adolescent Lives through Nutrition (Talent) consortium
Objective: Adolescent diet, physical activity and nutritional status are generally known to be sub-optimal. This is an introduction to a special issue of papers devoted to exploring factors affecting diet and physical activity in adolescents, including food insecure and vulnerable groups. Setting Eight settings including urban, peri-urban and rural across sites from five different low- and middle-income countries. Design: Focus groups with adoles…
A scoping review of literature describing the nutritional status and diets of adolescents in Côte d’Ivoire
Objective: Adolescents living in resource-limited settings remain a neglected population regarding their nutritional health. We reviewed what studies on nutrition have been conducted for adolescents living in Côte d’Ivoire. Design: A scoping literature review, searching for any quantitative studies published from 1 January 2000 to 1 May 2019, referenced in PubMed and grey literature, related to adolescent nutritional status and diet, written in E…
Évaluation quantitative de l’effet sur le passage aux urgences et les hospitalisations d’un dispositif départemental innovant de prise en charge des situations de crise durant l’adolescence en Haute-G…
Assessing the effects of the Covid-19 pandemic on new ART initiation and viral load access among children and adolescents living with HIV in West Africa
Background: Before the COVID-19 pandemic, the pediatric continuum of HIV care lagged behind that of adults. The present study aimed to describe the effects of the COVID-19 pandemic on access to HIV care among children and adolescents (0-19 years) living with HIV (CALHIV) in five West African countries. Methods: Within this observational multicenter study, we conducted an interrupted time series analysis by including all antiretroviral therapy (AR…
Prevalence and factors associated with severe illness in West African children under 5 years of age detected with routine pulse oximetry in primary care
BACKGROUND: The Integrated Management of Childhood Illness (IMCI) guidelines are symptom-based algorithms used to identify critically ill children under five in primary health centres (PHC) in resource-limited countries. Hypoxaemia, a life-threatening event, is clinically underdiagnosed. The Amélioration de l'Identification des détresses Respiratoires de l'Enfant/Improving Identification of Respiratory Distress in Children (AIRE) project implemen…
Missed opportunities for hospital referral of young children with severe pneumonia identified at primary care using pulse oximetry
Background In line with the Integrated Management of Childhood Illness (IMCI) guidelines, healthcare workers (HCWs) should refer all severe pneumonia among children under 5 seen in primary care in resource-limited settings. We investigated the frequency and correlates of missed opportunities for hospital referral (MOHR) of clinical severe pneumonia. Our study was embedded within the Améliorer l'Identification des détresses Respiratoires chez l'En…
Disparities in dolutegravir utilisation in children, adolescents and young adults (0–24 years) living with HIV. An analysis of the IeDEA Pediatric West African cohort
INTRODUCTION: We describe the 24-month incidence of Dolutegravir (DTG)-containing antiretroviral treatment (ART) initiation since its introduction in 2019 in West Africa. METHODS: We included all patients aged 0-24 years on ART from nine clinics in Côte d'Ivoire (n=4), Ghana, Nigeria, Mali, Benin, and Burkina Faso. Baseline varied by clinic and was defined as date of first DTG prescription; patients were followed up until database closure/death/l…
Care management and determinants of day 14 mortality in severely ill children aged under 5 years subsequent to hypoxaemia diagnosed using routine pulse oximetry in primary care
BACKGROUND: The Amélioration de l'Identification des détresses Respiratoires de l'Enfant (AIRE) project introduced the routine use of pulse oximetry (PO) into Integrated Management of Childhood Illness (IMCI) consultations within primary health centres (PHCs) in Burkina Faso, Guinea, Mali and Niger. We analysed how severe cases were managed and 14-day mortality by hypoxaemia severity. METHODS: <90%) were eligible for referral and enrolled in a 14…
Understanding health innovation adoption
INTRODUCTION: Hypoxaemia is an important contributor to child mortality, particularly in low-resource settings where diagnostic tools are scarce. The Améliorer l'Identification des détresses Respiratoires chez l'Enfant project introduced pulse oximeters (POs) into 202 primary healthcare centres (PHCs) in Burkina Faso, Guinea, Mali and Niger, integrating them into the Integrated Management of Childhood Illness guidelines. This initiative aimed to …
Acceptability of the routine use of pulse oximetry by healthcare workers and caregivers within primary healthcare in West Africa
INTRODUCTION: To better identify severe hypoxaemia as a major risk factor for specific illnesses in children aged under 5 years, the Améliorer l'Identification des détresses Respiratoires chez l'Enfant (AIRE) project implemented routine use of pulse oximetry within implementation of Integrated Management of Childhood Illness (IMCI) guidelines at primary health centres (PHCs) in Burkina Faso, Guinea, Mali and Niger. We aimed to measure and underst…
Household costs of care in children under five attending primary care in Burkina Faso, Guinea, Mali and Niger
INTRODUCTION: Out-of-pocket payments limit access to care in Africa. The Amélioration de l'Identification des détresses Respiratoires de l'Enfant/Improving Identification of Respiratory Distress in Children (AIRE) project evaluated the implementation of pulse oximetry within Integrated Management of Childhood Illness (IMCI) guidelines at primary health centres (PHCs) in Burkina Faso and Niger (with total exemption policies) and in Mali and Guinea…
Challenges and needs before implementing routine pulse oximetry within primary care for sick children in West Africa
BACKGROUND: The Integrated Management of Childhood Illness (IMCI) guidelines are implemented within primary health centres (PHCs) in resource-limited settings. These symptom-based algorithms under-diagnose severe hypoxemia, which contributes to the under-five'mortality in sub-Saharan Africa. To improve the diagnosis and management of severe hypoxaemia, the Améliorer l'Identification des détresses Respiratoires chez l'Enfant (AIRE) project impleme…
Perceptions and management of diabetes and obesity among people living with HIV in Côte d’Ivoire
These results highlight the complexity surrounding the perceptions and management of T2DM and obesity among PLHIV in Abidjan, Côte d'Ivoire. In order to implement innovative and efficient intervention strategies to prevent and treat these metabolic conditions, cultural beliefs as well as socio-economic barriers must be addressed
Medicine (18 obras) · HIV/AIDS Research and Interventions (17 obras) · Environmental health (11 obras) · Public health (11 obras) · Family medicine (9 obras) · Adolescent Sexual and Reproductive Health (8 obras) · Cohort (8 obras) · Pediatrics (8 obras) · Primary care (8 obras) · Demography (7 obras)