Luca Chiapperino
Datos Biográficos
| ID | 291002 |
|---|---|
| NOMBRE | Luca Chiapperino |
| NOMBRES | Luca |
| APELLIDO | Chiapperino |
| FIRMA | CHIAPPERINO L |
| AFILIACIONES | University of Lausanne |
| ORCID | 0000-0002-7071-7555 |
| VERIFICADO | Sí |
| TOTAL DE OBRAS | 15 |
| TOTAL DE CITAS | 24 |
| TOTAL COMO AUTOR | 15 |
| TOTAL COMO EDITOR | 0 |
| PRIMER AÑO DE PUBLICACIÓN | 2014 |
| AÑO MÁS RECIENTE DE PUBLICACIÓN | 2025 |
| ÍNDICE H | 3 |
Troubling the canon
STS is now a global endeavour, with journals, scholars, and associations in a wide range of regions, languages, and transnational networks of knowledge. Building on recent debates about decolonizing research, we contribute to debates about epistemic injustice and asymmetries in the discipline by analysing a large sample of articles in 17 STS journals, published between 1976 and 2023. Our goal is to understand the multiplicity of factors that shap…
Enacting biosocial complexity
This article analyses attempts to enact complexity in postgenomic experimentations using the case of epigenetic research on biomarkers of psychosocial stress. Enacting complexity in this research means dissecting multiple so-called biosocial processes of health differentiation in the face of stressful experiences. To characterize enactments of biosocial complexity, the article develops the concepts of complexity work and complexification . The fo…
A precision immuno-oncology turn? Hybridizing cancer genomics and immunotherapy through neoantigens-based adoptive cell therapies
This article explores the development of T cell-based therapies in Switzerland. These therapies, which elicit the immunological potential of each patient to respond to tumor development, constitute a major promise for so-called ‘precision oncology’. We document how immunological concepts, technologies, and practices are articulated given the centrality of genomics in ‘precision oncology’. We consider ‘precision immunotherapies’ to probe whether a…
Critiques from within. A modest proposal for reclaiming critique for responsible innovation
The anything-but-neutral relations between science, technology and society, at the core of science and technology studies, have led to the development of different repertoires of critique. None of them fitted the configurations in the biomedical practices we came to study. There, biomedical experts presented us with an analysis of the power relations perpetuated through the mainstream practices in their fields and had built socio-material alterna…
Between the genotype and the phenotype lies the microbiome
Emphatic claims of a "microbiome revolution" aside, the study of the gut microbiota and its role in organismal development and evolution is a central feature of so-called postgenomics; namely, a conceptual and/or practical turn in contemporary life sciences, which departs from genetic determinism and reductionism to explore holism, emergentism and complexity in biological knowledge-production. This paper analyses the making of postgenomic knowled…
Translating Planetary Health Principles Into Sustainable Primary Care Services
Global anthropogenic environmental degradations such as climate change are increasingly recognized as critical public health issues, on which human beings should urgently act in order to preserve sustainable conditions of living on Earth. “Planetary Health” is a breakthrough concept and emerging research field based on the recognition of the interdependent relationships between living organisms—both human and non-human—and their ecosystems. In th…
Environmental enrichment
On the traces of the biosocial
This paper builds upon historico-epistemological analyses of plasticity across the nineteenth and twentieth centuries to distinguish among uses of this notion in contemporary epigenetics. By digging into this diachronic phase of plasticity thinking, we highlight a series of historically situated understandings and pragmatic dimensions of this notion. Specifically, our analysis describes four distinct phases in plasticity thinking across the ninet…
Luck and the responsibilities to protect one’s epigenome
This paper builds upon the debate on ‘moral luck’ – i.e. the import that factors beyond one's control have on the cogency of normative claims such as responsibilities – to criticise claims towards backward- and forward-looking responsibilities to protect one's epigenome for the sake of personal or future generations' health. Luck, I argue, is part and parcel with the actions required to protect our epigenomes, and points to the need of dismissing…
Epistemic dwelling
This paper details how the architectural features of a new cancer research center (henceforth “NCRC”) contribute to the alignment of different institutional settings, epistemic approaches and communities of practices around precision immuno-oncology. First, we show how the building’s designed emplacement produces an organizational change directed at accelerating the traffic of discoveries and the collaborations across basic research and clinical …
Gendered imaginaries
Our paper explores the value-laden and epistemic resources that scientists working in epigenetics and developmental programming of health and disease (DOHaD) mobilise to produce scientific representations of pregnancy and parenthood, which in turn imagine norms, values, and responsibilities for the protection of future generations. In order to do so, we first describe the place of questions regarding the relative weight of paternal and maternal i…
The European politics of animal experimentation
This paper identifies a common political struggle behind debates on the validity and permissibility of animal experimentation, through an analysis of two recent European case studies: the Italian implementation of the European Directive 2010/63/EC regulating the use of animals in science, and the recent European Citizens' Initiative (ECI) 'Stop Vivisection'. Drawing from a historical parallel with Victorian antivivisectionism, we highlight import…
The epigenomic self in personalized medicine
The Epigenomic Self in Personalized Medicine
This paper focuses on two areas of innovation currently articulating the agenda of personalized medicine (PM): the discourse of empowerment in health-care reforms and the rise of molecular epigenomics. We align these two developments as discursive and technical resources, focusing on their nascent interplay in shaping alternative sociotechnical imaginaries of PM. Our work aims at inaugurating an intellectual programme on the distinct futures of p…
Rethinking Medical Humanities
Gendered imaginaries
Our paper explores the value-laden and epistemic resources that scientists working in epigenetics and developmental programming of health and disease (DOHaD) mobilise to produce scientific representations of pregnancy and parenthood, which in turn imagine norms, values, and responsibilities for the protection of future generations. In order to do so, we first describe the place of questions regarding the relative weight of paternal and maternal i…
A precision immuno-oncology turn? Hybridizing cancer genomics and immunotherapy through neoantigens-based adoptive cell therapies
This article explores the development of T cell-based therapies in Switzerland. These therapies, which elicit the immunological potential of each patient to respond to tumor development, constitute a major promise for so-called ‘precision oncology’. We document how immunological concepts, technologies, and practices are articulated given the centrality of genomics in ‘precision oncology’. We consider ‘precision immunotherapies’ to probe whether a…
On the traces of the biosocial
This paper builds upon historico-epistemological analyses of plasticity across the nineteenth and twentieth centuries to distinguish among uses of this notion in contemporary epigenetics. By digging into this diachronic phase of plasticity thinking, we highlight a series of historically situated understandings and pragmatic dimensions of this notion. Specifically, our analysis describes four distinct phases in plasticity thinking across the ninet…
The Epigenomic Self in Personalized Medicine
This paper focuses on two areas of innovation currently articulating the agenda of personalized medicine (PM): the discourse of empowerment in health-care reforms and the rise of molecular epigenomics. We align these two developments as discursive and technical resources, focusing on their nascent interplay in shaping alternative sociotechnical imaginaries of PM. Our work aims at inaugurating an intellectual programme on the distinct futures of p…
Enacting biosocial complexity
This article analyses attempts to enact complexity in postgenomic experimentations using the case of epigenetic research on biomarkers of psychosocial stress. Enacting complexity in this research means dissecting multiple so-called biosocial processes of health differentiation in the face of stressful experiences. To characterize enactments of biosocial complexity, the article develops the concepts of complexity work and complexification . The fo…
The European politics of animal experimentation
This paper identifies a common political struggle behind debates on the validity and permissibility of animal experimentation, through an analysis of two recent European case studies: the Italian implementation of the European Directive 2010/63/EC regulating the use of animals in science, and the recent European Citizens' Initiative (ECI) 'Stop Vivisection'. Drawing from a historical parallel with Victorian antivivisectionism, we highlight import…
Rethinking Medical Humanities
The epigenomic self in personalized medicine
The Epigenomic Self in Personalized Medicine
This paper focuses on two areas of innovation currently articulating the agenda of personalized medicine (PM): the discourse of empowerment in health-care reforms and the rise of molecular epigenomics. We align these two developments as discursive and technical resources, focusing on their nascent interplay in shaping alternative sociotechnical imaginaries of PM. Our work aims at inaugurating an intellectual programme on the distinct futures of p…
The European politics of animal experimentation
This paper identifies a common political struggle behind debates on the validity and permissibility of animal experimentation, through an analysis of two recent European case studies: the Italian implementation of the European Directive 2010/63/EC regulating the use of animals in science, and the recent European Citizens' Initiative (ECI) 'Stop Vivisection'. Drawing from a historical parallel with Victorian antivivisectionism, we highlight import…
Gendered imaginaries
Our paper explores the value-laden and epistemic resources that scientists working in epigenetics and developmental programming of health and disease (DOHaD) mobilise to produce scientific representations of pregnancy and parenthood, which in turn imagine norms, values, and responsibilities for the protection of future generations. In order to do so, we first describe the place of questions regarding the relative weight of paternal and maternal i…
Luck and the responsibilities to protect one’s epigenome
This paper builds upon the debate on ‘moral luck’ – i.e. the import that factors beyond one's control have on the cogency of normative claims such as responsibilities – to criticise claims towards backward- and forward-looking responsibilities to protect one's epigenome for the sake of personal or future generations' health. Luck, I argue, is part and parcel with the actions required to protect our epigenomes, and points to the need of dismissing…
Epistemic dwelling
This paper details how the architectural features of a new cancer research center (henceforth “NCRC”) contribute to the alignment of different institutional settings, epistemic approaches and communities of practices around precision immuno-oncology. First, we show how the building’s designed emplacement produces an organizational change directed at accelerating the traffic of discoveries and the collaborations across basic research and clinical …
Environmental enrichment
On the traces of the biosocial
This paper builds upon historico-epistemological analyses of plasticity across the nineteenth and twentieth centuries to distinguish among uses of this notion in contemporary epigenetics. By digging into this diachronic phase of plasticity thinking, we highlight a series of historically situated understandings and pragmatic dimensions of this notion. Specifically, our analysis describes four distinct phases in plasticity thinking across the ninet…
Translating Planetary Health Principles Into Sustainable Primary Care Services
Global anthropogenic environmental degradations such as climate change are increasingly recognized as critical public health issues, on which human beings should urgently act in order to preserve sustainable conditions of living on Earth. “Planetary Health” is a breakthrough concept and emerging research field based on the recognition of the interdependent relationships between living organisms—both human and non-human—and their ecosystems. In th…
Critiques from within. A modest proposal for reclaiming critique for responsible innovation
The anything-but-neutral relations between science, technology and society, at the core of science and technology studies, have led to the development of different repertoires of critique. None of them fitted the configurations in the biomedical practices we came to study. There, biomedical experts presented us with an analysis of the power relations perpetuated through the mainstream practices in their fields and had built socio-material alterna…
Between the genotype and the phenotype lies the microbiome
Emphatic claims of a "microbiome revolution" aside, the study of the gut microbiota and its role in organismal development and evolution is a central feature of so-called postgenomics; namely, a conceptual and/or practical turn in contemporary life sciences, which departs from genetic determinism and reductionism to explore holism, emergentism and complexity in biological knowledge-production. This paper analyses the making of postgenomic knowled…
Enacting biosocial complexity
This article analyses attempts to enact complexity in postgenomic experimentations using the case of epigenetic research on biomarkers of psychosocial stress. Enacting complexity in this research means dissecting multiple so-called biosocial processes of health differentiation in the face of stressful experiences. To characterize enactments of biosocial complexity, the article develops the concepts of complexity work and complexification . The fo…
A precision immuno-oncology turn? Hybridizing cancer genomics and immunotherapy through neoantigens-based adoptive cell therapies
This article explores the development of T cell-based therapies in Switzerland. These therapies, which elicit the immunological potential of each patient to respond to tumor development, constitute a major promise for so-called ‘precision oncology’. We document how immunological concepts, technologies, and practices are articulated given the centrality of genomics in ‘precision oncology’. We consider ‘precision immunotherapies’ to probe whether a…
Troubling the canon
STS is now a global endeavour, with journals, scholars, and associations in a wide range of regions, languages, and transnational networks of knowledge. Building on recent debates about decolonizing research, we contribute to debates about epistemic injustice and asymmetries in the discipline by analysing a large sample of articles in 17 STS journals, published between 1976 and 2023. Our goal is to understand the multiplicity of factors that shap…
Sociology (12 obras) · Epistemology (10 obras) · Race, Genetics, and Society (8 obras) · Political science (7 obras) · Biology (6 obras) · Psychology (6 obras) · Engineering (5 obras) · Engineering ethics (5 obras) · Law (5 obras) · Philosophy (5 obras)