Patricia A Ganz
Datos Biográficos
| ID | 3424310 |
|---|---|
| NOMBRE | Patricia A Ganz |
| NOMBRES | Patricia A |
| APELLIDO | Ganz |
| FIRMA | GANZ P A |
| AFILIACIONES | University of California, Los Angeles |
| ORCID | 0000-0002-1841-4143 |
| VERIFICADO | Sí |
| TOTAL DE OBRAS | 30 |
| TOTAL DE CITAS | 9 |
| TOTAL COMO AUTOR | 30 |
| TOTAL COMO EDITOR | 0 |
| PRIMER AÑO DE PUBLICACIÓN | 1992 |
| AÑO MÁS RECIENTE DE PUBLICACIÓN | 2024 |
| ÍNDICE H | 2 |
Mediators of a Mindfulness-Based Intervention for Younger Breast Cancer Survivors
OBJECTIVE: Depression is associated with poor outcomes in breast cancer patients, with higher prevalence among younger women. Although mindfulness-based interventions (MBIs) have demonstrated therapeutic effects, the mechanisms of intervention effects are poorly understood. We investigated whether rumination, self-kindness, intrusive thoughts about cancer, cancer-related worry, or a sense of meaning and peace mediated the intervention effects of …
Overall side effect assessment of oxaliplatin toxicity in rectal cancer patients in NRG oncology/NSABP R04
GOV: NCT00058474
Simulation study comparing analytical methods for single-item longitudinal patient-reported outcomes data
Although the CLMM showed the best performance among analytical methods, it relies on assumptions difficult to verify and that might not be fulfilled in the real world, therefore our recommendation is the use of PIM models with baseline symptom as a covariate
Executive Functioning and Depressive Symptoms After Cancer
OBJECTIVE: Cognitive difficulties are a common complaint among patients with breast cancer and may adversely affect psychological well-being. In particular, problems with executive functioning (EF) may interfere with coping, which is known to influence depressive symptoms. The current study was designed to examine correlations between EF, coping, and depressive symptoms in breast cancer survivors and to longitudinally test the hypothesis that cop…
Cortisol Awakening Response as a Prospective Risk Factor for Depressive Symptoms in Women After Treatment for Breast Cancer
OBJECTIVE: The aim of the study was to investigate hypothalamic-pituitary-adrenal axis (HPA axis) functioning as a neurobiological risk factor for depressive symptoms in an ongoing longitudinal, observational study of women undergoing treatment and recovery from breast cancer. Many women with breast cancer experience depressive symptoms that interfere with their treatment, recovery, and quality of life. Psychosocial risk factors for depression am…
Positive Affect and Inflammatory Activity in Breast Cancer Survivors
OBJECTIVE: Given the importance of positive affect and inflammation for well-being in cancer survivors, the current study examined the relationship between high- and low-arousal positive affect and inflammation in 186 women who completed treatment of early-stage breast cancer. METHODS: Measures of high- and low-arousal positive affect were completed within 3 months after treatment completion (baseline). Plasma markers of inflammation, including s…
Life after diagnosis and treatment of cancer in adulthood
The number of individuals living with a history of cancer is estimated at 13.7 million in the United States and is expected to rise with the aging of the population. With expanding attention to the psychosocial and physical consequences of surviving illness, psychological science and evidence-based practice are making important contributions to addressing the pressing needs of cancer survivors. Research is demonstrating that adults diagnosed with…
Childhood Adversity and Inflammation in Breast Cancer Survivors
OBJECTIVE: Elevated inflammation predicts behavioral symptoms, disease progression, and mortality in patients with breast cancer and breast cancer survivors, although predictors of inflammation remain largely unknown. Adverse experiences in childhood have been associated with higher rates of psychological and physical illness, and elevated inflammatory activity in studies of healthy adults. However, little research has examined the association be…
Physicians’ Beliefs About Breast Cancer Surveillance Testing are Consistent With Test Overuse
BACKGROUND: Overuse of surveillance testing for breast cancer survivors is an important problem but its extent and determinants are incompletely understood. The objectives of this study were to determine the extent to which physicians' breast cancer surveillance testing beliefs are consistent with test overuse, and to identify factors associated with these beliefs. METHODS: During 2009-2010, a cross-sectional survey of US medical oncologists and …
The eight-item modified Medical Outcomes Study Social Support Survey
A procedure for obtaining Impact of Cancer version 2 scores using version 1 responses
Men's adjustment after their partners' complete treatment for localized breast cancer
Impact of Physician–Patient Discussions on Patient Satisfaction
BACKGROUND: When 2 treatment choices (ie, mastectomy vs. breast conserving therapy) show no difference in a primary clinical outcome (ie, survival), patient satisfaction becomes an important marker of the quality of care received. OBJECTIVES: To assess the impact of physician-patient discussion of primary surgical treatment outcomes on patients' satisfaction with medical care (MC) among women with incident breast cancer (BC). METHOD: We used self…
Altered Cortisol Response to Psychologic Stress in Breast Cancer Survivors With Persistent Fatigue
OBJECTIVE: Fatigue is one of the most common and distressing symptoms experienced by cancer patients and survivors. However, the etiology of cancer-related fatigue has not been determined. In previous studies, we have shown alterations in morning serum cortisol levels and diurnal cortisol rhythms in fatigued breast cancer survivors compared with nonfatigued control subjects. The purpose of the current study was to evaluate cortisol responses to a…
Influence of exercise activity on quality of life in long-term breast cancer survivors
Quality of Life in Diverse Groups of Midlife Women
The Relationship Among Physicians’ Specialty, Perceptions of the Risks and Benefits of Adjuvant Tamoxifen Therapy, and Its Recommendation in Older Patients With Breast Cancer
OBJECTIVES: The objectives of this study were to determine whether tamoxifen recommendation differs by physician specialty, to determine whether perception affects tamoxifen recommendation, and to investigate the association between the physician's specialty and the perception of risks and benefits of tamoxifen. METHODS: We enrolled a cohort of geographically diverse women aged 65 and older with stage I through IIIa breast cancer in a prospective…
Fatigue and Proinflammatory Cytokine Activity in Breast Cancer Survivors
OBJECTIVE: Fatigue is a common problem among cancer patients and survivors, yet the mechanisms underlying the occurrence and persistence of this symptom are not known. Activation of the immune system may evoke feelings of fatigue, which are mediated by proinflammatory cytokines. We examined whether fatigued breast cancer survivors would show elevations in proinflammatory cytokines and markers of cytokine activity compared with nonfatigued survivo…
Quality of life in advanced non-small-cell lung cancer
Developing a Reliable, Valid, and Feasible Plan for Quality-of-Care Measurement for Cancer
Background. Recent changes in the US health care delivery system have raised expectations that the medical marketplace will compete on quality and cost of care. This effort will require a systematic evaluation of the measurement of quality of care as it applies to cancer and other critical conditions. Objectives. To articulate the components of the design of quality-of-care measurement systems that must be considered and optimally manipulated to …
What Outcomes Matter to Patients
BACKGROUND: During the last quarter of the 20th century, it became feasible to measure and take into account the patient's subjective preferences for health states and various outcomes. This has become increasingly relevant in the treatment of cancer, where patients are confronted with a life-threatening illness and may have varied treatment choices and outcomes. OBJECTIVES: To provide a framework for examining the outcomes that matter to patient…
Psychologic Distress and Natural Menopause
Objectives. This study examined the association between psychologic distress and natural menopause in a community sample of African American, White, Chinese, Hispanic, and Japanese women participating in a national women's health study. Methods. A cohort of 16 065 women aged 40 to 55 years provided information on menstrual regularity in the previous year, psychosocial factors, health, and somatic–psychologic symptoms. Psychologic distress was def…
The Ucla Prostate Cancer Index
OBJECTIVES: The need for accurate measures of health-related quality of life (HRQOL) in men treated for prostate cancer is of paramount importance because patients may survive for many years after their diagnosis. Hence, interest has increased in choosing treatments that optimize both the quality and quantity of life in patients with this disease. This study sought to develop and evaluate a self-administered, multiitem, disease-specific instrumen…
Translation and validation of a quality of life instrument for hispanic American cancer patients
Symbiotic relationships of quality of life, health services research and other health research
Psychologic Distress and Natural Menopause
Objectives. This study examined the association between psychologic distress and natural menopause in a community sample of African American, White, Chinese, Hispanic, and Japanese women participating in a national women's health study. Methods. A cohort of 16 065 women aged 40 to 55 years provided information on menstrual regularity in the previous year, psychosocial factors, health, and somatic–psychologic symptoms. Psychologic distress was def…
Life after diagnosis and treatment of cancer in adulthood
The number of individuals living with a history of cancer is estimated at 13.7 million in the United States and is expected to rise with the aging of the population. With expanding attention to the psychosocial and physical consequences of surviving illness, psychological science and evidence-based practice are making important contributions to addressing the pressing needs of cancer survivors. Research is demonstrating that adults diagnosed with…
Report from a National Cancer Institute (USA) workshop on quality of life assessment in cancer clinical trials
Assessing the needs and quality of life of patients with HIV infection
The Cares
Predicting Psychosocial Risk in Patients With Breast Cancer
Breast cancer is the most common neoplasm in North American women. The psychosocial impact of breast cancer has been extensively studied, and a number of investigators have attempted to characterize women who are at high risk for increased psychosocial morbidity. Although a detailed interview performed by a professional is the clinical standard for psychosocial assessment, such interviews are usually time-consuming and expensive, and thus are rar…
Symbiotic relationships of quality of life, health services research and other health research
Quality of life in adult survivors of lung, colon and prostate cancer
Translation and validation of a quality of life instrument for hispanic American cancer patients
The Ucla Prostate Cancer Index
OBJECTIVES: The need for accurate measures of health-related quality of life (HRQOL) in men treated for prostate cancer is of paramount importance because patients may survive for many years after their diagnosis. Hence, interest has increased in choosing treatments that optimize both the quality and quantity of life in patients with this disease. This study sought to develop and evaluate a self-administered, multiitem, disease-specific instrumen…
Psychologic Distress and Natural Menopause
Objectives. This study examined the association between psychologic distress and natural menopause in a community sample of African American, White, Chinese, Hispanic, and Japanese women participating in a national women's health study. Methods. A cohort of 16 065 women aged 40 to 55 years provided information on menstrual regularity in the previous year, psychosocial factors, health, and somatic–psychologic symptoms. Psychologic distress was def…
Fatigue and Proinflammatory Cytokine Activity in Breast Cancer Survivors
OBJECTIVE: Fatigue is a common problem among cancer patients and survivors, yet the mechanisms underlying the occurrence and persistence of this symptom are not known. Activation of the immune system may evoke feelings of fatigue, which are mediated by proinflammatory cytokines. We examined whether fatigued breast cancer survivors would show elevations in proinflammatory cytokines and markers of cytokine activity compared with nonfatigued survivo…
Quality of life in advanced non-small-cell lung cancer
Developing a Reliable, Valid, and Feasible Plan for Quality-of-Care Measurement for Cancer
Background. Recent changes in the US health care delivery system have raised expectations that the medical marketplace will compete on quality and cost of care. This effort will require a systematic evaluation of the measurement of quality of care as it applies to cancer and other critical conditions. Objectives. To articulate the components of the design of quality-of-care measurement systems that must be considered and optimally manipulated to …
What Outcomes Matter to Patients
BACKGROUND: During the last quarter of the 20th century, it became feasible to measure and take into account the patient's subjective preferences for health states and various outcomes. This has become increasingly relevant in the treatment of cancer, where patients are confronted with a life-threatening illness and may have varied treatment choices and outcomes. OBJECTIVES: To provide a framework for examining the outcomes that matter to patient…
Quality of Life in Diverse Groups of Midlife Women
The Relationship Among Physicians’ Specialty, Perceptions of the Risks and Benefits of Adjuvant Tamoxifen Therapy, and Its Recommendation in Older Patients With Breast Cancer
OBJECTIVES: The objectives of this study were to determine whether tamoxifen recommendation differs by physician specialty, to determine whether perception affects tamoxifen recommendation, and to investigate the association between the physician's specialty and the perception of risks and benefits of tamoxifen. METHODS: We enrolled a cohort of geographically diverse women aged 65 and older with stage I through IIIa breast cancer in a prospective…
Altered Cortisol Response to Psychologic Stress in Breast Cancer Survivors With Persistent Fatigue
OBJECTIVE: Fatigue is one of the most common and distressing symptoms experienced by cancer patients and survivors. However, the etiology of cancer-related fatigue has not been determined. In previous studies, we have shown alterations in morning serum cortisol levels and diurnal cortisol rhythms in fatigued breast cancer survivors compared with nonfatigued control subjects. The purpose of the current study was to evaluate cortisol responses to a…
Influence of exercise activity on quality of life in long-term breast cancer survivors
Impact of Physician–Patient Discussions on Patient Satisfaction
BACKGROUND: When 2 treatment choices (ie, mastectomy vs. breast conserving therapy) show no difference in a primary clinical outcome (ie, survival), patient satisfaction becomes an important marker of the quality of care received. OBJECTIVES: To assess the impact of physician-patient discussion of primary surgical treatment outcomes on patients' satisfaction with medical care (MC) among women with incident breast cancer (BC). METHOD: We used self…
The eight-item modified Medical Outcomes Study Social Support Survey
A procedure for obtaining Impact of Cancer version 2 scores using version 1 responses
Men's adjustment after their partners' complete treatment for localized breast cancer
Physicians’ Beliefs About Breast Cancer Surveillance Testing are Consistent With Test Overuse
BACKGROUND: Overuse of surveillance testing for breast cancer survivors is an important problem but its extent and determinants are incompletely understood. The objectives of this study were to determine the extent to which physicians' breast cancer surveillance testing beliefs are consistent with test overuse, and to identify factors associated with these beliefs. METHODS: During 2009-2010, a cross-sectional survey of US medical oncologists and …
Childhood Adversity and Inflammation in Breast Cancer Survivors
OBJECTIVE: Elevated inflammation predicts behavioral symptoms, disease progression, and mortality in patients with breast cancer and breast cancer survivors, although predictors of inflammation remain largely unknown. Adverse experiences in childhood have been associated with higher rates of psychological and physical illness, and elevated inflammatory activity in studies of healthy adults. However, little research has examined the association be…
Life after diagnosis and treatment of cancer in adulthood
The number of individuals living with a history of cancer is estimated at 13.7 million in the United States and is expected to rise with the aging of the population. With expanding attention to the psychosocial and physical consequences of surviving illness, psychological science and evidence-based practice are making important contributions to addressing the pressing needs of cancer survivors. Research is demonstrating that adults diagnosed with…
Positive Affect and Inflammatory Activity in Breast Cancer Survivors
OBJECTIVE: Given the importance of positive affect and inflammation for well-being in cancer survivors, the current study examined the relationship between high- and low-arousal positive affect and inflammation in 186 women who completed treatment of early-stage breast cancer. METHODS: Measures of high- and low-arousal positive affect were completed within 3 months after treatment completion (baseline). Plasma markers of inflammation, including s…
Medicine (28 obras) · Cancer survivorship and care (21 obras) · Cancer (20 obras) · Internal Medicine (19 obras) · Breast cancer (14 obras) · Internal Medicine (14 obras) · Psychology (13 obras) · Gerontology (10 obras) · Quality of life (healthcare (10 obras) · Nursing (9 obras)