Ene Metspalu

Datos Biográficos

ID3459944
NOMBREEne Metspalu
NOMBRESEne
APELLIDOMetspalu
FIRMAMETSPALU E
AFILIACIONESEstonian Biocentre
ORCID0000-0001-6247-7291
VERIFICADOSí
TOTAL DE OBRAS16
TOTAL DE CITAS27
TOTAL COMO AUTOR16
TOTAL COMO EDITOR0
PRIMER AÑO DE PUBLICACIÓN2003
AÑO MÁS RECIENTE DE PUBLICACIÓN2016
ÍNDICE H1

  • The Simons Genome Diversity Project

    Open AccessSwapan Mallick, Heng Li et al.ARTICLENature2016

    Here we report the Simons Genome Diversity Project data set: high quality genomes from 300 individuals from 142 diverse populations. These genomes include at least 5.8 million base pairs that are not present in the human reference genome. Our analysis reveals key features of the landscape of human genome variation, including that the rate of accumulation of mutations has accelerated by about 5% in non-Africans compared to Africans since divergenc…

  • Genomic evidence for the Pleistocene and recent population history of Native Americans

    Open AccessMaanasa Raghavan, Matthias Steinrücken et al.ARTICLEScience2015

    Genetic history of Native Americans Several theories have been put forth as to the origin and timing of when Native American ancestors entered the Americas. To clarify this controversy, Raghavan et al. examined the genomic variation among ancient and modern individuals from Asia and the Americas. There is no evidence for multiple waves of entry or recurrent gene flow with Asians in northern populations. The earliest migrations occurred no earlier…

  • Ancient human genomes suggest three ancestral populations for present-day Europeans

    Open AccessIosif Lazaridis, Nick Patterson et al.ARTICLENature2014

  • Upper Palaeolithic Siberian genome reveals dual ancestry of Native Americans

    Open AccessMaanasa Raghavan, Peter Skoglund et al.ARTICLENature2014

  • Ancient DNA Reveals Matrilineal Continuity in Present-Day Poland over the Last Two Millennia

    Open AccessAnna Juras, Miroslawa Dabert et al.ARTICLEPLoS ONE2014

    While numerous ancient human DNA datasets from across Europe have been published till date, modern-day Poland in particular, remains uninvestigated. Besides application in the reconstruction of continent-wide human history, data from this region would also contribute towards our understanding of the history of the Slavs, whose origin is hypothesized to be in East or Central Europe. Here, we present the first population-scale ancient human DNA stu…

  • No Evidence from Genome-wide Data of a Khazar Origin for the Ashkenazi Jews

    Doron M Behar, Mait Metspalu et al.ARTICLEHuman Biology2013

    The origin and history of the Ashkenazi Jewish population have long been of great interest, and advances in high-throughput genetic analysis have recently provided a new approach for investigating these topics. We and others have argued on the basis of genome-wide data that the Ashkenazi Jewish population derives its ancestry from a combination of sources tracing to both Europe and the Middle East. It has been claimed, however, through a reanalys…

  • No Evidence from Genome-wide Data of a Khazar Origin fo the Ashkenazi Jews

    Doron M Behar, Doron M Behar Doron M Behar et al.ARTICLEHuman Biology2013

    The origin and history of the Ashkenazi Jewish population have long been of great interest, and advances in high-throughput genetic analysis have recently provided a new approach for investigating these topics. We and others have argued on the basis of genome-wide data that the Ashkenazi Jewish population derives its ancestry from a combination of sources tracing to both Europe and the Middle East. It has been claimed, however, through a reanalys…

  • Genetic affinities of Ukrainians from the maternal perspective

    Open AccessAndrey Pshenichnov, Oleg Balanovsky et al.ARTICLEAmerican Journal of Physical…2013Referencias: 12

    The area of what is now the Ukraine has been the arena of large‐scale demographic processes that may have left their traces in the contemporary gene pool of Ukrainians. In this study, we present new mitochondrial DNA data for 607 Ukrainians (hypervariable segment I sequences and coding region polymorphisms). To study the maternal affinities of Ukrainians at the level of separate mitochondrial haplotypes, we apply an original technique, the haplot…

  • Evolution of the Pygmy Phenotype

    Andrea Bamberg Migliano, Andrea Bamberg Migliano Andrea Bamberg Migliano et al.ARTICLEHuman Biology2013Citada por: 27Referencias: 88

    Human pygmy populations inhabit different regions of the world, from Africa to Melanesia. In Asia, short-statured populations are often referred to as "negritos." Their short stature has been interpreted as a consequence of thermoregulatory, nutritional, and/or locomotory adaptations to life in tropical forests. A more recent hypothesis proposes that their stature is the outcome of a life history trade-off in high-mortality environments, where ea…

  • Influence of evolutionary forces and demographic processes on the genetic structure of three Croatian populations

    Open AccessJelena Šarac, Tena Šarić et al.ARTICLEAnnals of Human Biology2012

    The results can be explained by the effect evolutionary forces have on genetic structure, which is in line with the specific demographic histories of the islands. An additional research value of these two island isolates is the appearance of certain Mendelian disorders, highlighting their importance in epidemiological studies

  • An Aboriginal Australian Genome Reveals Separate Human Dispersals into Asia

    Open AccessMorten Rasmussen, Xiaosen Guo et al.ARTICLEScience2011

    Whole-genome data indicate that early modern humans expanded into Australia 62,000 to 75,000 years ago.

  • Ancient human genome sequence of an extinct Palaeo-Eskimo

    Open AccessMorten Rasmussen, Yingrui Li et al.ARTICLENature2010

    We report here the genome sequence of an ancient human. Obtained from ∼4,000-year-old permafrost-preserved hair, the genome represents a male individual from the first known culture to settle in Greenland. Sequenced to an average depth of 20×, we recover 79% of the diploid genome, an amount close to the practical limit of current sequencing technologies. We identify 353,151 high-confidence single-nucleotide polymorphisms (SNPs), of which 6.8% hav…

  • An mtDNA perspective of French genetic variation

    Open AccessChrystelle Richard, Erwan Pennarun et al.ARTICLEAnnals of Human Biology2007

    The mtDNA haplogroup composition of the French does not differ significantly from the surrounding European genetic landscape. At a finer grain, microgeographical differentiation can be revealed, as shown for the French Basque country and for Brittany

  • The unresolved location of Ötzi's mtDNA within haplogroup K

    Open AccessPhillip Endicott, Juan J Sanchez et al.ARTICLEAmerican Journal of Physical…2007Referencias: 6

    Aging Medicine is an open access journal for international collaboration in multiple research disciplines across the aging sciences. The American Journal of Biological Anthropology is a physical anthropology publication, accepting evolutionary articles in bioarcheology, human & primate biology, & more

  • Most of the extant mtDNA boundaries in South and Southwest Asia were likely shaped during the initial settlement of Eurasia by anatomically modern humans

    Open AccessMait Metspalu, Toomas Kivisild et al.ARTICLEBMC Genetics2004

  • The Genetic Heritage of the Earliest Settlers Persists Both in Indian Tribal and Caste Populations

    Open AccessToomas Kivisild, Siiri Rootsi et al.ARTICLEThe American Journal of Human…2003