Lucia Knight

Datos Biográficos

ID3583476
NOMBRELucia Knight
NOMBRESLucia
APELLIDOKnight
FIRMAKNIGHT L
AFILIACIONESUniversity of Cape Town
ORCID0000-0001-9938-6887
VERIFICADOSí
TOTAL DE OBRAS43
TOTAL DE CITAS12
TOTAL COMO AUTOR43
TOTAL COMO EDITOR0
PRIMER AÑO DE PUBLICACIÓN2014
AÑO MÁS RECIENTE DE PUBLICACIÓN2026
ÍNDICE H2

  • Determinants and Strategies for Implementation of an Adapted Data to Care Vertical HIV Prevention Intervention in a South African Context

    Open AccessYolanda Gomba, Lucia Knight et al.ARTICLEAIDS and Behavior2026

    Despite progress in preventing new HIV infections in children, retention in vertical transmission prevention (VTP) remains a challenge in low-resource settings. The REMInD intervention used an adapted Data to Care (D2C) approach with tracing to support mother-infant pairs in completing VTP care. This qualitative study aimed to explore the potential implementation determinants and strategies to enhance the successful implementation of the REMInD i…

  • The Impact of a Household Intervention on ART Adherence and Household HIV Competency for People Living with HIV

    Open AccessLinda S Campbell, Caroline Masquillier et al.ARTICLEAIDS and Behavior2026

  • Beyond the Diagnosis

    Open AccessNeo Sematlane, Lucia Knight et al.ARTICLEAIDS and Behavior2026

    This study utilizes the illness identity framework to investigate the incorporation of HIV into a sense of self and how varying degrees of integration influence key patient-reported outcomes. Using baseline data from the SINAKO Cluster Randomised Controlled Trial, we analysed responses from 316 adults living with HIV (PLHIV) attending 12 healthcare facilities in the Cape metropole, South Africa. Respondents completed assessments on four illness i…

  • Household-level factors and ART adherence among people living with HIV in Cape Town, South Africa

    Lorraine Tanyaradzwa Dube, Caroline Masquillier et al.ARTICLEAIDS Care2026

    South Africa has the largest ART programme in the world. ART is provided within the context of the universal test and treat strategy. Sustained high levels of ART adherence are required to ensure viral suppression and prevent ART-drug resistance. However, poor ART adherence remains a challenge in South Africa. While much research has focused on individual - and community-level factors influencing adherence, household-level factors remain under-re…

  • Interest in long-acting injectable antiretroviral therapy (ART) among adults living with HIV newly starting or restarting ART in Cape Town, South Africa

    Open AccessTamsin K Phillips, Mpumelelo Zondo et al.ARTICLEAIDS Care2026

    Long-acting injectable antiretroviral therapy (LAI ART) has proven effective in maintaining viral suppression among people living with HIV but recommendations to switch to LAI ART are limited to individuals stable and virologically suppressed on oral ART. Understanding LAI perceptions among diverse populations living with HIV is essential. In a cross-sectional survey at two peri-urban clinics in Cape Town, adults starting or restarting treatment …

  • Reasons for HIV testing and testing experiences among men testing for HIV in Cape Town, South Africa

    Open AccessTsidiso Tolla, Edwin Wouters et al.ARTICLEAIDS Care2026

    6) (5-7 participants per group). Participants were purposively selected. Thematic analysis, guided by the conceptual framework of access to healthcare, was applied. Testing was influenced by (a) healthcare workers initiating HIV testing, which men generally accepted, (b) the availability of male-friendly and men's clinics, which were limited, but approachable and preferred over general facilities, and (c) men's engagement in sexual behaviours tha…

  • Exploration of Pregnant and Breastfeeding Women’s Acceptability of Rapid Point-of-Care Urine Testing Within Antenatal and Postnatal Care, and Its Perceived Impact on PrEP Adherence When Paired with Pr…

    Open AccessLara Court, Rufaro Mvududu et al.ARTICLEAIDS and Behavior2026

  • The not talking is actually what kills you’– young South African women’s communication barriers about sexual health

    Open AccessFelicity Hartley, Jill Trappler et al.ARTICLECulture Health & Sexuality2026

    Conversations about sex and sexual health are often stigmatised and shaped by socio-cultural influences. For young women, lack of adequate communication can influence access to information, knowledge and behaviour and therefore increase vulnerability to negative outcomes such as sexually transmitted infections (STIs) and unintended pregnancy. This qualitative study investigated the barriers young women face when seeking dialogue about sex, their …

  • Exploring factors affecting the decision-making process among adolescents and youth in KwaZulu-Natal in accessing and utilising sexual reproductive health services

    Open AccessZimasa Tshawe, Nonzwakazi Natasha Gcelu et al.ARTICLECulture Health & Sexuality2026

    Despite improved access to sexual and reproductive health services, uptake among adolescents and young people remains low. Supporting their decision-making and addressing barriers to service use is critical to improving HIV prevention, reducing sexually transmitted infections, improving treatment outcomes, and preventing early pregnancies. This analysis explored factors influencing participants sexual and reproductive health service use decisions…

  • Public good, mindful bodies and human rights

    Open AccessAlberto Caoci, Lucia Knight et al.ARTICLEJournal of Social Distress and…2025

    This paper explores unhoused people’s health-related experiences and perceptions of the implementation of the City of Cape Town’s COVID-19 policy involving the movement of people to the “Strandfontein Camp”, undertaken during the South African lockdown from March to April 2020. This policy was intended to serve as a public health measure to protect people from the spread of the virus. It ultimately resulted in the forced relocation of about 1600 …

  • Interventions to reduce HIV-related stigma among older people living with HIV in sub-Saharan Africa

    Open AccessHannah M Wolpe, Lucia Knight et al.ARTICLEAIDS Care2025

    HIV-related stigma remains a major barrier to testing, treatment, and quality of life, especially for the growing population of older people living with HIV (OPLWH, aged 50+). Such stigma intersects with age-related and other stigmas, compounding health vulnerabilities. Research on this issue remains limited, particularly in sub-Saharan Africa (SSA). This review thus sought to explore stigma-reduction interventions for OPLWH in SSA to inform futu…

  • Interpersonal factors associated with depression symptom severity among PrEP-naïve pregnant women in South Africa

    Anvita Bhardwaj, Madison R Fertig et al.ARTICLEAIDS Care2025

    Depression during pregnancy is linked to reduced use and adherence to pre-exposure prophylaxis (PrEP), increasing HIV risk. However, few studies explore how interpersonal factors shape depressive symptoms in pregnant women. We surveyed 110 pregnant women in Cape Town, South Africa, assessing depression and three interpersonal constructs: reproductive autonomy, dyadic trust, and relationship power. Participants had a mean age of 25.7 years and a m…

  • Psychosocial factors associated with the willingness to initiate and continue PrEP during pregnancy among PrEP-naïve persons in South Africa

    Hyo Jin Shin, Lauren Gulbicki et al.ARTICLEAIDS Care2025

    In South Africa (SA), women are disproportionately affected by HIV, with increased risk during the peripartum period. Despite the availability, efficacy, and safety of oral PrEP to prevent HIV, uptake and adherence rates remain low. This study assessed the association of intrapersonal, partner-related, and community-referenced psychosocial factors with willingness to use PrEP among pregnant persons in SA. PrEP-naïve pregnant persons receiving ant…

  • “As an older person my thoughts do not focus on one thing”

    Open AccessKatie Bradley, Jennifer A Pellowski et al.ARTICLEAIDS Care2025

    In South Africa, HIV prevalence among people over 50 exceeds 18.5%, yet research and interventions for older people living with HIV (OPLWH) remain limited. Evidence links HIV stigma to poor health outcomes, but little is known about OPLWH's experiences in resource-limited settings. This study explores how OPLWH understand and experience intersecting stigmas, and how these shape engagement in care. Using a qualitative exploratory design, we conduc…

  • I’ll Continue If I Have a Positive Mind”

    Open AccessAmelia M Stanton, Madison R Fertig et al.ARTICLEInternational Journal of…2025

    Pregnant and postpartum people (PPPs) face heightened risk for HIV acquisition, yet depression and trauma-related symptoms can undermine adherence to pre-exposure prophylaxis (PrEP). To inform the development of a brief mental health-focused adherence intervention, we explored the impacts of depression and posttraumatic stress disorder (PTSD) symptoms on PrEP use among PPPs in Cape Town, South Africa. Twenty-eight PPPs with elevated symptoms of d…

  • Routine Electronic Mother-Infant Data (ReminD)

    Open AccessTamsin K Phillips, Yolanda Gomba et al.ARTICLEAIDS and Behavior2025

    Data to Care (D2C) strategies- using routine data to identify and re-engage people living with HIV who are not in care- have shown promise in high-income settings but remain underexplored in lower-resource and vertical HIV transmission prevention (VTP) contexts. In this prospective, single-arm, proof-of-concept study, we used facility-linked public sector electronic medical records (Provincial Health Data Centre [PHDC] data) to identify, validate…

  • Experiences of alcohol use during pregnancy

    Open AccessAmanda P Miller, Lara Court et al.ARTICLESSM - Qualitative Research in…2024

    In South Africa, alcohol use during pregnancy is prevalent and associated with increased HIV risk. Developing locally sensitive and contextually appropriate evidence-based interventions to address alcohol use among pregnant and breastfeeding women in South Africa requires comprehensive understanding of the context of perinatal alcohol use and how relationships and lived environments may serve as barriers or supports for alcohol reduction. We cond…

  • Experiences of transfer of care among postpartum women living with HIV attending primary healthcare services in South Africa

    Open AccessJasantha Odayar, Landon Myers et al.ARTICLEGlobal Public Health2024

    Transfers between health facilities for postpartum women living with HIV are associated with disengagement from care. In South Africa, women must transfer from integrated antenatal/HIV care to general HIV services post-delivery. Thereafter, women transfer frequently e.g. due to geographic mobility. To explore barriers to transfer, we conducted in-depth interviews >2 years post-delivery in 28 participants in a trial comparing postpartum HIV care a…

  • I Have to Stand Up on My Own and Do the Best I Can for My Kids”a

    Open AccessMamaswatsi Kopeka, M Barton Laws et al.ARTICLEAIDS and Behavior2024

    In recent years, significant progress has been made in treatment access for women living with HIV (WLHIV). For example, option B+, which requires that all pregnant persons who test positive for HIV start on antiretroviral treatment, has been instrumental in reducing the risk of vertical transmission. For birthing individuals who have a low HIV viral load, there is a minimized risk of vertical transmission during breastfeeding. However, an alarmin…

  • Attitudes, Beliefs, and Predictors of Gestational Weight Gain and Postpartum Weight Retention in South Africa

    Open AccessChelsie Cintron, Hlengiwe P Madlala et al.ARTICLEAIDS and Behavior2024

  • Including the Household

    Open AccessLinda Campbell, Linda S Campbell et al.ARTICLEAIDS and Behavior2024

    Antiretroviral therapy (ART) adherence is crucial for health outcomes of people living with HIV (PLHIV), influenced by a complex interplay of individual, community, and household factors. This article focuses on the influence of household factors, as well as individual and community factors, on ART adherence among PLHIV in Cape Town who have recently initiated ART. Baseline data for a cluster-randomized controlled trial were collected from 316 PL…

  • Perceptions of the Covid-19 pandemic

    Open AccessTakana M Silubonde, Lucia Knight et al.ARTICLEBMC Public Health2023

    With the existing mistrust of government, there is need for government to leverage existing trusted sources in communities to aid in the implementation of preventative measures. These findings support the development of context specific solutions to address challenges faced at different socioeconomic levels

  • Exploring Self-reported Adherence Measures to Screen for Elevated HIV Viral Load in Adolescents

    Open AccessSiyanai Zhou, Elona Toska et al.ARTICLEAIDS and Behavior2023

    The timely identification of ART non-adherence among adolescents living with HIV presents a significant challenge, particularly in resource-limited settings where virologic monitoring is suboptimal. Using South African adolescent cohort data (N = 933, mean age 13.6 ± 2.89 years, 55.1% female, follow-up = 2014-2018), we examined the association between elevated viral load (VL ≥ 1000 copies/mL) and seven self-reported adherence measures on missed d…

  • A difficult conversation’

    Lucia Knight, Hilton Humphries et al.ARTICLECulture Health & Sexuality2023

    Adolescence and young adulthood are important periods of transition and therefore for action and intervention to ensure future sexual and reproductive health (SRH). Caregiver-adolescent communication about sex and sexuality is a protective factor for SRH, but there are often barriers to this. Adults' perspectives are limited within the literature but important as they should lead this process. This paper uses exploratory qualitative data from in-…

  • Social Support for Improved ART Adherence and Retention in Care among Older People Living with HIV in Urban South Africa

    Open AccessLucia Knight, Enid SchatzARTICLEInternational Journal of…2022

    The number of older people living with HIV (OPLWH) (aged 50-plus) in South Africa is increasing as people age with HIV or are newly infected. OPLWH are potentially vulnerable because of the intersection of age-related and HIV stigmas, co-morbidities, and lack of social support. Evidence from younger populations suggests that social support can improve ART adherence and retention in care. Further, HIV status disclosure plays a role in mediating so…