Denise Evans
Datos Biográficos
| ID | 3583714 |
|---|---|
| NOMBRE | Denise Evans |
| NOMBRES | Denise |
| APELLIDO | Evans |
| FIRMA | EVANS D |
| AFILIACIONES | University of the Witwatersrand |
| ORCID | 0000-0003-0698-1228 |
| VERIFICADO | Sí |
| TOTAL DE OBRAS | 25 |
| TOTAL DE CITAS | 1 |
| TOTAL COMO AUTOR | 25 |
| TOTAL COMO EDITOR | 0 |
| PRIMER AÑO DE PUBLICACIÓN | 2011 |
| AÑO MÁS RECIENTE DE PUBLICACIÓN | 2026 |
| ÍNDICE H | 1 |
Missed PrEP opportunities and vulnerability to HIV during rifampicin-resistant tuberculosis treatment in South Africa
Background: Adults receiving rifampicin-resistant TB (RR-TB) treatment have prolonged engagement with the health system, yet healthcare professionals frequently miss opportunities to promote HIV prevention-particularly pre-exposure prophylaxis (PrEP)-in high-burden settings. We examined HIV vulnerability, PrEP awareness and uptake, and HIV and sexually transmitted infection (STI) incidence among HIV-negative adults receiving RR-TB treatment. Meth…
‘It all depends on your faith’
Despite biomedical explanations for diseases being increasingly accepted in sub-Saharan Africa, traditional African explanatory models of illness remain widespread. This study sought to understand local explanatory models for illness and patient experiences with different traditional health practitioners (THPs) among a population of rural women in Limpopo, South Africa. This was a cross-sectional qualitative study in which eighty-two in-depth int…
Physiological Markers of Early Social Skills in Rural South Africa
Early social skills underlie the development of crucial regulatory and behavioral processes across childhood. EEG frontal alpha asymmetry and heart rate variability are two physiological markers that have been extensively studied in relation to social skills in high‐income country (HIC) samples. The prevalence of adversities in low‐ and middle‐income countries (LMICs) is linked to pervasive deficits in early social skills, yet little is known abo…
Food plants and their past circulation in Central-Western Argentinean Patagonia
One year on - the long-term impact of Covid-19 pandemic and government restrictions on the health-seeking behaviour, financial security and mental health of TB survivors
Clinical trial number: not applicable
Understanding treatment initiation pathways and associated costs among people with pulmonary tuberculosis in a peri-urban area of Mozambique
Most people with TB symptoms sought care within two weeks but TB treatment initiation was delayed to nearly two months after symptoms onset. This suggests that delays in TB treatment initiation may be attributable to health system factors rather than the care-seeking behaviour of people with TB in Maputo, Mozambique. Additionally, there was a substantial financial burden of care-seeking exacerbated by additional healthcare provider visits. Eviden…
Traditional beliefs and practices surrounding pregnancy loss in Limpopo Province, South Africa
South Africa has a diversity of traditional beliefs and practices within its existing sub-cultures which include complex belief patterns around women's sexual and reproductive health, including pregnancy loss (i.e. abortion or miscarriage). Causes of pregnancy loss among the different cultures can be attributed broadly to ancestors, bewitchment, and ritual pollution. However, of these factors, ritual pollution has not been adequately researched. …
Adopting sustainable innovations for remote access to TB and HIV care in South Africa
For the last decade, South Africa has made substantial progress to control the dual HIV and TB epidemics. However, disruptions in TB and HIV treatment during the COVID-19 pandemic threatened to reverse this. This study aimed to identify adaptations in HIV and TB service delivery models in response to COVID-19 and government restrictions. This information informed the development of an online survey, which was utilized as part of a consultation ex…
The lived experiences of tuberculosis survivors during the Covid-19 pandemic and government lockdown in South Africa
Implications and suggestions for future directions include fostering and maintaining a strong network of social support for TB survivors
TB morbidity estimates overlook the contribution of post-TB disability
Introduction Despite growing evidence of the long-term impact of tuberculosis (TB) on quality of life, Global Burden of Disease (GBD) estimates of TB-related disability-adjusted life years (DALYs) do not include post-TB morbidity, and evaluations of TB interventions typically assume treated patients return to pre-TB health. Using primary data, we estimate years of life lost due to disability (YLDs), years of life lost due to premature mortality (…
Survey of Adherence with Covid-19 Prevention Behaviors During the 2020 Thanksgiving and Winter Holidays Among Members of the Covid-19 Community Research Partnership
Prevention behaviors represent important public health tools to limit spread of SARS-CoV-2. Adherence with recommended public health prevention behaviors among 20000 + members of a COVID-19 syndromic surveillance cohort from the mid-Atlantic and southeastern United States was assessed via electronic survey following the 2020 Thanksgiving and winter holiday (WH) seasons. Respondents were predominantly non-Hispanic Whites (90%), female (60%), and ≥…
Reduction in initiations of drug-sensitive tuberculosis treatment in South Africa during the Covid-19 pandemic
In response to the global pandemic of COVID-19, South Africa implemented a strict lockdown in March 2020 before its first COVID-19 wave started, gradually lifted restrictions between May and September 2020, and then re-imposed restrictions in December 2020 in response to its second wave. There is concern that COVID-19-related morbidity and mortality, the deprioritization of TB activities, fear of transmission, and societal restrictions led to a r…
Assessment of facility-based tuberculosis data quality in an integrated HIV/TB database in three South African districts
Background Assessment of data quality is essential to successful monitoring & evaluation of tuberculosis (TB) services. South Africa uses the Three Interlinked Electronic Register (TIER.Net) to monitor TB diagnoses and treatment outcomes. We assessed the quality of routine programmatic data as captured in TIER.Net. Methods We reviewed 277 records from routine data collected for adults who had started TB treatment for drug-sensitive (DS-) TB betwe…
Arqueoproteómica como complemento de estudios paleopatológicos en restos óseos humanos de la Cueva de Plaza, Chubut, Argentina
En este trabajo se propone realizar por primera vez en Argentina un análisis proteómico por espectrometría de masas de una falange humana con una alteración macroscópica proveniente de un conjunto arqueológico recuperado en el sitio Cueva de Plaza (Chubut, Argentina). Se presentan dos métodos de extracción de proteínas de restos óseos arqueológicos para ser analizadas con un espectrómetro de masas. Ambos métodos permitieron obtener resultados no …
Adaptation of WHO’s generic tuberculosis patient cost instrument for a longitudinal study in Africa
The WHO developed a generic ‘TB patient cost survey’ tool and a standardized approach to assess the direct and indirect costs of TB incurred by patients and their households, estimate the proportion of patients experiencing catastrophic costs, and measure the impact of interventions to reduce patient costs. While the generic tool is a facility-based cross-sectional survey, this standardized approach needs to be adapted for longitudinal studies. A…
Postpartum Mental Health in Rural South Africa
Community health worker models in South Africa
South Africa has a long history of community health workers (CHWs). It has been a journey that has required balancing constrained resources and competing priorities. CHWs form a bridge between communities and healthcare service provision within health facilities and act as the cornerstone of South Africa’s Ward-Based Primary Healthcare Outreach Teams. This study aimed to document the CHW policy implementation landscape across six provinces in Sou…
The New Zealand Family Group Conference Confidentiality Protections
With the adoption of statutes, policies and administrative guidance since the late 1980s, statutory child welfare agencies around the world have been implementing practice approaches to resolving and addressing child abuse and neglect concerns that involve extended family systems in decision making and planning. One such approach is the family group conference (FGC), enshrined in New Zealand law. This article provides a historical context and des…
Treatment outcomes among children, adolescents, and adults on treatment for tuberculosis in two metropolitan municipalities in Gauteng Province, South Africa
Young adults in urban areas of Gauteng Province experience a disproportionate burden of LTFU and low coverage of ART among co-infected patients. This group should be targeted for interventions aimed at improving clinical outcomes and retention in both TB and HIV care
Data quality of drug-resistant tuberculosis and antiretroviral therapy electronic registers in South Africa
The underreporting of death and the lack of ART or TB status in the electronic DR-TB and ART registers could negatively impact monitoring efforts by downplaying the state of the TB/HIV epidemic. Improved recording of these data sources, and data integration across systems, could improve the accuracy of reporting for the national HIV/ART and TB programs
Dietary intake among paediatric HIV-positive patients initiating antiretroviral therapy in Johannesburg, South Africa
In South Africa, prevention of mother to child transmission (PMTCT) has reduced MTCT from 3.6% in 2011 to 1.3% in 2017. However, there are challenges in reaching vulnerable HIV-positive children; those at increased risk of malnutrition or present late with advanced disease. Macro – and micronutrient deficiencies, common in HIV, may accelerate disease progression. This was a prospective cohort study of paediatric patients (aged 1–10 years) initiat…
Social and behavioral factors associated with failing second-line ART – results from a cohort study at the Themba Lethu Clinic, Johannesburg, South Africa
Poor adherence is a main challenge to successful second-line ART in South Africa. Studies have shown that patients can re-suppress their viral load following intensive adherence counselling. We identify factors associated with failure to re-suppress on second-line ART. The study was a retrospective cohort study which included HIV-positive adults who experienced an elevated viral load ≥400 copies/ml on second-line ART between January 2013-July 201…
Understanding Perspectives of African American Medicaid-Insured Women on the Process of Perinatal Care
Can Short-Term Use of Electronic Patient Adherence Monitoring Devices Improve Adherence in Patients Failing Second-Line Antiretroviral Therapy? Evidence from a Pilot Study in Johannesburg, South Afric…
High levels of adherence are required to achieve the full benefit of ART. We assess the effectiveness of electronic adherence monitoring devices among patients failing second-line ART, as measured by viral load suppression. Cohort study of WisepillTM real-time adherence monitoring in addition to intensified adherence counselling over 3 months in adults with a viral load ≥400 copies/ml on second-line ART in Johannesburg, South Africa between Augus…
Paediatric human immunodeficiency virus treatment outcomes from a resource-limited setting in South Africa
Comprehensive care of human immunodeficiency virus (HIV)-infected children in the resource-poor setting is challenging, and published reports on treatment outcomes in this setting are limited. The aim of this study was to evaluate outcomes of HIV-infected children initiated on highly active antiretroviral therapy (HAART) between April 2005 and April 2009 at a primary health-care centre in Alexandra Township, South Africa. Of the 337 patients init…
Paediatric human immunodeficiency virus treatment outcomes from a resource-limited setting in South Africa
Comprehensive care of human immunodeficiency virus (HIV)-infected children in the resource-poor setting is challenging, and published reports on treatment outcomes in this setting are limited. The aim of this study was to evaluate outcomes of HIV-infected children initiated on highly active antiretroviral therapy (HAART) between April 2005 and April 2009 at a primary health-care centre in Alexandra Township, South Africa. Of the 337 patients init…
Paediatric human immunodeficiency virus treatment outcomes from a resource-limited setting in South Africa
Comprehensive care of human immunodeficiency virus (HIV)-infected children in the resource-poor setting is challenging, and published reports on treatment outcomes in this setting are limited. The aim of this study was to evaluate outcomes of HIV-infected children initiated on highly active antiretroviral therapy (HAART) between April 2005 and April 2009 at a primary health-care centre in Alexandra Township, South Africa. Of the 337 patients init…
Can Short-Term Use of Electronic Patient Adherence Monitoring Devices Improve Adherence in Patients Failing Second-Line Antiretroviral Therapy? Evidence from a Pilot Study in Johannesburg, South Afric…
High levels of adherence are required to achieve the full benefit of ART. We assess the effectiveness of electronic adherence monitoring devices among patients failing second-line ART, as measured by viral load suppression. Cohort study of WisepillTM real-time adherence monitoring in addition to intensified adherence counselling over 3 months in adults with a viral load ≥400 copies/ml on second-line ART in Johannesburg, South Africa between Augus…
Understanding Perspectives of African American Medicaid-Insured Women on the Process of Perinatal Care
Social and behavioral factors associated with failing second-line ART – results from a cohort study at the Themba Lethu Clinic, Johannesburg, South Africa
Poor adherence is a main challenge to successful second-line ART in South Africa. Studies have shown that patients can re-suppress their viral load following intensive adherence counselling. We identify factors associated with failure to re-suppress on second-line ART. The study was a retrospective cohort study which included HIV-positive adults who experienced an elevated viral load ≥400 copies/ml on second-line ART between January 2013-July 201…
Treatment outcomes among children, adolescents, and adults on treatment for tuberculosis in two metropolitan municipalities in Gauteng Province, South Africa
Young adults in urban areas of Gauteng Province experience a disproportionate burden of LTFU and low coverage of ART among co-infected patients. This group should be targeted for interventions aimed at improving clinical outcomes and retention in both TB and HIV care
Data quality of drug-resistant tuberculosis and antiretroviral therapy electronic registers in South Africa
The underreporting of death and the lack of ART or TB status in the electronic DR-TB and ART registers could negatively impact monitoring efforts by downplaying the state of the TB/HIV epidemic. Improved recording of these data sources, and data integration across systems, could improve the accuracy of reporting for the national HIV/ART and TB programs
Dietary intake among paediatric HIV-positive patients initiating antiretroviral therapy in Johannesburg, South Africa
In South Africa, prevention of mother to child transmission (PMTCT) has reduced MTCT from 3.6% in 2011 to 1.3% in 2017. However, there are challenges in reaching vulnerable HIV-positive children; those at increased risk of malnutrition or present late with advanced disease. Macro – and micronutrient deficiencies, common in HIV, may accelerate disease progression. This was a prospective cohort study of paediatric patients (aged 1–10 years) initiat…
The New Zealand Family Group Conference Confidentiality Protections
With the adoption of statutes, policies and administrative guidance since the late 1980s, statutory child welfare agencies around the world have been implementing practice approaches to resolving and addressing child abuse and neglect concerns that involve extended family systems in decision making and planning. One such approach is the family group conference (FGC), enshrined in New Zealand law. This article provides a historical context and des…
Adaptation of WHO’s generic tuberculosis patient cost instrument for a longitudinal study in Africa
The WHO developed a generic ‘TB patient cost survey’ tool and a standardized approach to assess the direct and indirect costs of TB incurred by patients and their households, estimate the proportion of patients experiencing catastrophic costs, and measure the impact of interventions to reduce patient costs. While the generic tool is a facility-based cross-sectional survey, this standardized approach needs to be adapted for longitudinal studies. A…
Postpartum Mental Health in Rural South Africa
Community health worker models in South Africa
South Africa has a long history of community health workers (CHWs). It has been a journey that has required balancing constrained resources and competing priorities. CHWs form a bridge between communities and healthcare service provision within health facilities and act as the cornerstone of South Africa’s Ward-Based Primary Healthcare Outreach Teams. This study aimed to document the CHW policy implementation landscape across six provinces in Sou…
TB morbidity estimates overlook the contribution of post-TB disability
Introduction Despite growing evidence of the long-term impact of tuberculosis (TB) on quality of life, Global Burden of Disease (GBD) estimates of TB-related disability-adjusted life years (DALYs) do not include post-TB morbidity, and evaluations of TB interventions typically assume treated patients return to pre-TB health. Using primary data, we estimate years of life lost due to disability (YLDs), years of life lost due to premature mortality (…
Survey of Adherence with Covid-19 Prevention Behaviors During the 2020 Thanksgiving and Winter Holidays Among Members of the Covid-19 Community Research Partnership
Prevention behaviors represent important public health tools to limit spread of SARS-CoV-2. Adherence with recommended public health prevention behaviors among 20000 + members of a COVID-19 syndromic surveillance cohort from the mid-Atlantic and southeastern United States was assessed via electronic survey following the 2020 Thanksgiving and winter holiday (WH) seasons. Respondents were predominantly non-Hispanic Whites (90%), female (60%), and ≥…
Reduction in initiations of drug-sensitive tuberculosis treatment in South Africa during the Covid-19 pandemic
In response to the global pandemic of COVID-19, South Africa implemented a strict lockdown in March 2020 before its first COVID-19 wave started, gradually lifted restrictions between May and September 2020, and then re-imposed restrictions in December 2020 in response to its second wave. There is concern that COVID-19-related morbidity and mortality, the deprioritization of TB activities, fear of transmission, and societal restrictions led to a r…
Assessment of facility-based tuberculosis data quality in an integrated HIV/TB database in three South African districts
Background Assessment of data quality is essential to successful monitoring & evaluation of tuberculosis (TB) services. South Africa uses the Three Interlinked Electronic Register (TIER.Net) to monitor TB diagnoses and treatment outcomes. We assessed the quality of routine programmatic data as captured in TIER.Net. Methods We reviewed 277 records from routine data collected for adults who had started TB treatment for drug-sensitive (DS-) TB betwe…
Arqueoproteómica como complemento de estudios paleopatológicos en restos óseos humanos de la Cueva de Plaza, Chubut, Argentina
En este trabajo se propone realizar por primera vez en Argentina un análisis proteómico por espectrometría de masas de una falange humana con una alteración macroscópica proveniente de un conjunto arqueológico recuperado en el sitio Cueva de Plaza (Chubut, Argentina). Se presentan dos métodos de extracción de proteínas de restos óseos arqueológicos para ser analizadas con un espectrómetro de masas. Ambos métodos permitieron obtener resultados no …
The lived experiences of tuberculosis survivors during the Covid-19 pandemic and government lockdown in South Africa
Implications and suggestions for future directions include fostering and maintaining a strong network of social support for TB survivors
Adopting sustainable innovations for remote access to TB and HIV care in South Africa
For the last decade, South Africa has made substantial progress to control the dual HIV and TB epidemics. However, disruptions in TB and HIV treatment during the COVID-19 pandemic threatened to reverse this. This study aimed to identify adaptations in HIV and TB service delivery models in response to COVID-19 and government restrictions. This information informed the development of an online survey, which was utilized as part of a consultation ex…
One year on - the long-term impact of Covid-19 pandemic and government restrictions on the health-seeking behaviour, financial security and mental health of TB survivors
Clinical trial number: not applicable
Understanding treatment initiation pathways and associated costs among people with pulmonary tuberculosis in a peri-urban area of Mozambique
Most people with TB symptoms sought care within two weeks but TB treatment initiation was delayed to nearly two months after symptoms onset. This suggests that delays in TB treatment initiation may be attributable to health system factors rather than the care-seeking behaviour of people with TB in Maputo, Mozambique. Additionally, there was a substantial financial burden of care-seeking exacerbated by additional healthcare provider visits. Eviden…
Traditional beliefs and practices surrounding pregnancy loss in Limpopo Province, South Africa
South Africa has a diversity of traditional beliefs and practices within its existing sub-cultures which include complex belief patterns around women's sexual and reproductive health, including pregnancy loss (i.e. abortion or miscarriage). Causes of pregnancy loss among the different cultures can be attributed broadly to ancestors, bewitchment, and ritual pollution. However, of these factors, ritual pollution has not been adequately researched. …
Missed PrEP opportunities and vulnerability to HIV during rifampicin-resistant tuberculosis treatment in South Africa
Background: Adults receiving rifampicin-resistant TB (RR-TB) treatment have prolonged engagement with the health system, yet healthcare professionals frequently miss opportunities to promote HIV prevention-particularly pre-exposure prophylaxis (PrEP)-in high-burden settings. We examined HIV vulnerability, PrEP awareness and uptake, and HIV and sexually transmitted infection (STI) incidence among HIV-negative adults receiving RR-TB treatment. Meth…
‘It all depends on your faith’
Despite biomedical explanations for diseases being increasingly accepted in sub-Saharan Africa, traditional African explanatory models of illness remain widespread. This study sought to understand local explanatory models for illness and patient experiences with different traditional health practitioners (THPs) among a population of rural women in Limpopo, South Africa. This was a cross-sectional qualitative study in which eighty-two in-depth int…
Physiological Markers of Early Social Skills in Rural South Africa
Early social skills underlie the development of crucial regulatory and behavioral processes across childhood. EEG frontal alpha asymmetry and heart rate variability are two physiological markers that have been extensively studied in relation to social skills in high‐income country (HIC) samples. The prevalence of adversities in low‐ and middle‐income countries (LMICs) is linked to pervasive deficits in early social skills, yet little is known abo…
Food plants and their past circulation in Central-Western Argentinean Patagonia
Medicine (20 obras) · Environmental health (12 obras) · Tuberculosis Research and Epidemiology (11 obras) · Tuberculosis (10 obras) · Public health (9 obras) · Nursing (8 obras) · Pediatrics (8 obras) · Internal Medicine (7 obras) · Geography (6 obras) · HIV/AIDS Research and Interventions (6 obras)