David A Larsen
Datos Biográficos
| ID | 359484 |
|---|---|
| NOMBRE | David A Larsen |
| NOMBRES | David A |
| APELLIDO | Larsen |
| FIRMA | LARSEN D A |
| AFILIACIONES | Syracuse University |
| ORCID | 0000-0002-1876-6536 |
| VERIFICADO | Sí |
| TOTAL DE OBRAS | 14 |
| TOTAL DE CITAS | 1 |
| TOTAL COMO AUTOR | 14 |
| TOTAL COMO EDITOR | 0 |
| PRIMER AÑO DE PUBLICACIÓN | 2001 |
| AÑO MÁS RECIENTE DE PUBLICACIÓN | 2025 |
| ÍNDICE H | 1 |
A geo-enabled digital tool for microplanning and delivery of indoor residual spray in Zambia
Indoor residual spraying (IRS) is a vector control tool recommended by the WHO in areas of high malaria burden. Effective IRS implementation is complicated when up-to-date and accurate counts of structures eligible for IRS are unavailable; resultingly, programmatic spray coverage is typically calculated as the proportion of found structures that are sprayed. From 2016 – 2020 in Zambia, an open-source tool termed “Reveal,” was used to support digi…
How local health departments use wastewater surveillance data for public health planning and intervention in New York State
Wastewater surveillance presents a novel data stream for local health departments to understand infectious disease risk in their communities. We conducted a survey of local health departments in New York State regarding their knowledge, attitudes, and practices toward wastewater surveillance of SARS-CoV-2. We further conducted in-depth interviews with a number of local health departments to identify specific use cases of wastewater surveillance d…
Precision public health in schools enabled by wastewater surveillance
Wastewater surveillance provides a cost-effective and non-invasive way to gain an understanding of infectious disease transmission including for COVID-19. We analyzed wastewater samples from one school site in Jefferson County, New York during the 2021–2022 school year. We tested for SARS-CoV-2 RNA once weekly and compared those results with the clinical COVID-19 cases in the school. The amount of SARS-CoV-2 RNA correlated with the number of inci…
Non-detection of emerging and re-emerging pathogens in wastewater surveillance to confirm absence of transmission risk
Infectious disease surveillance systems, including wastewater surveillance, can alert communities to the threat of emerging pathogens. We need methods to infer understanding of transmission dynamics from non-detection. We estimate a sensitivity of detection of poliovirus in wastewater to inform the sensitivity of wastewater surveillance for poliovirus using both a clinical epidemiology and fecal shedding approach. We then apply freedom from disea…
Using geographic information systems to link population estimates to wastewater surveillance data in New York State, USA
Sewer systems provide many services to communities that have access to them beyond removal of waste and wastewater. Understanding of these systems’ geographic coverage is essential for wastewater-based epidemiology (WBE), which requires accurate estimates for the population contributing wastewater. Reliable estimates for the boundaries of a sewer service area or sewershed can be used to link upstream populations to wastewater samples taken at tre…
Reactive focal drug administration associated with decreased malaria transmission in an elimination setting
Efforts to eliminate malaria transmission need evidence-based strategies. However, accurately assessing end-game malaria elimination strategies is challenging due to the low level of transmission and the rarity of infections. We hypothesised that presumptively treating individuals during reactive case detection (RCD) would reduce transmission and that serology would more sensitively detect this change over standard approaches. We conducted a clus…
High Sensitivity and Specificity of Dormitory-Level Wastewater Surveillance for Covid-19 during Fall Semester 2020 at Syracuse University, New York
A residential building's wastewater presents a potential non-invasive method of surveilling numerous infectious diseases, including SARS-CoV-2. We analyzed wastewater from 16 different residential locations at Syracuse University (Syracuse, NY, USA) during fall semester 2020, testing for SARS-CoV-2 RNA twice weekly and compared the presence of clinical COVID-19 cases to detection of the viral RNA in wastewater. The sensitivity of wastewater surve…
Mosquito Net Fishing as a Normal Accident and the Roles of Traditional and Bureaucratic Authority
In the 1980s, malaria researchers experimented with treating mosquito nets with pyrethroids chemicals to kill mosquitoes (insecticide-treated net or ITN). In the mid-2000s, world health agencies determined that ITNs should be distributed freely. Since then more than two billion ITNs have been distributed throughout malaria-endemic countries. In regions where fishing is an important economic activity the ITNs have been repurposed for fishing. The …
Community-level impacts of sanitation coverage on maternal and neonatal health
Introduction Access to sanitation facilities (toilets or latrines) greatly improves human health. Low community sanitation coverage may lead to increased exposure to pathogens for households both with and without a sanitation facility. Methods We created a retrospective cohort using Demographic and Health Surveys from 1990 through 2018. Using regression with matched women as a random intercept, we assessed the association between community-level …
Wastewater Surveillance for Sars-CoV-2 on College Campuses
Wastewater surveillance for the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an emerging approach to help identify the risk of a coronavirus disease (COVID-19) outbreak. This tool can contribute to public health surveillance at both community (wastewater treatment system) and institutional (e.g., colleges, prisons, and nursing homes) scales. This paper explores the successes, challenges, and lessons learned from initial wastewa…
Examining Wealth Trends in Kombewa, Kenya
A disruptive cue improves handwashing in school children in Zambia
Behavioral economics hold great promise in changing patterns of behavior that influence human health. Handwashing with soap is one such behavior that is important in reducing exposure to pathogens, and in school-age children, handwashing helps reduce absenteeism through the prevention of respiratory and diarrheal diseases. However, the gap between knowledge on the importance of handwashing and actual handwashing practice, especially with soap, pe…
Household Dengue Prevention Interventions, Expenditures, and Barriers to Aedes aegypti Control in Machala, Ecuador
The Aedes aegypti mosquito is an efficient vector for the transmission of Zika, chikungunya, and dengue viruses, causing major epidemics and a significant social and economic burden throughout the tropics and subtropics. The primary means of preventing these diseases is household-level mosquito control. However, relatively little is known about the economic burden of Ae. aegypti control in resource-limited communities. We surveyed residents from …
South Park's Solar Anus, or, Rabelais Returns
South Park, as a narration of late capitalist concerns, has much in common with works from earlier carnival historical epochs, most importantly Gargantua and Pantagruel and its depiction of folk traditions of consumptive culture. Madness, hallucination, excrement, homosexuality, cuckoldry, flowering anuses, zombies, monstrosity, gambling, banquets, viral contagion, grotesque consumption all become signs of a historical epoch which exists in a rep…
South Park's Solar Anus, or, Rabelais Returns
South Park, as a narration of late capitalist concerns, has much in common with works from earlier carnival historical epochs, most importantly Gargantua and Pantagruel and its depiction of folk traditions of consumptive culture. Madness, hallucination, excrement, homosexuality, cuckoldry, flowering anuses, zombies, monstrosity, gambling, banquets, viral contagion, grotesque consumption all become signs of a historical epoch which exists in a rep…
Household Dengue Prevention Interventions, Expenditures, and Barriers to Aedes aegypti Control in Machala, Ecuador
The Aedes aegypti mosquito is an efficient vector for the transmission of Zika, chikungunya, and dengue viruses, causing major epidemics and a significant social and economic burden throughout the tropics and subtropics. The primary means of preventing these diseases is household-level mosquito control. However, relatively little is known about the economic burden of Ae. aegypti control in resource-limited communities. We surveyed residents from …
A disruptive cue improves handwashing in school children in Zambia
Behavioral economics hold great promise in changing patterns of behavior that influence human health. Handwashing with soap is one such behavior that is important in reducing exposure to pathogens, and in school-age children, handwashing helps reduce absenteeism through the prevention of respiratory and diarrheal diseases. However, the gap between knowledge on the importance of handwashing and actual handwashing practice, especially with soap, pe…
Community-level impacts of sanitation coverage on maternal and neonatal health
Introduction Access to sanitation facilities (toilets or latrines) greatly improves human health. Low community sanitation coverage may lead to increased exposure to pathogens for households both with and without a sanitation facility. Methods We created a retrospective cohort using Demographic and Health Surveys from 1990 through 2018. Using regression with matched women as a random intercept, we assessed the association between community-level …
Wastewater Surveillance for Sars-CoV-2 on College Campuses
Wastewater surveillance for the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an emerging approach to help identify the risk of a coronavirus disease (COVID-19) outbreak. This tool can contribute to public health surveillance at both community (wastewater treatment system) and institutional (e.g., colleges, prisons, and nursing homes) scales. This paper explores the successes, challenges, and lessons learned from initial wastewa…
Examining Wealth Trends in Kombewa, Kenya
Reactive focal drug administration associated with decreased malaria transmission in an elimination setting
Efforts to eliminate malaria transmission need evidence-based strategies. However, accurately assessing end-game malaria elimination strategies is challenging due to the low level of transmission and the rarity of infections. We hypothesised that presumptively treating individuals during reactive case detection (RCD) would reduce transmission and that serology would more sensitively detect this change over standard approaches. We conducted a clus…
High Sensitivity and Specificity of Dormitory-Level Wastewater Surveillance for Covid-19 during Fall Semester 2020 at Syracuse University, New York
A residential building's wastewater presents a potential non-invasive method of surveilling numerous infectious diseases, including SARS-CoV-2. We analyzed wastewater from 16 different residential locations at Syracuse University (Syracuse, NY, USA) during fall semester 2020, testing for SARS-CoV-2 RNA twice weekly and compared the presence of clinical COVID-19 cases to detection of the viral RNA in wastewater. The sensitivity of wastewater surve…
Mosquito Net Fishing as a Normal Accident and the Roles of Traditional and Bureaucratic Authority
In the 1980s, malaria researchers experimented with treating mosquito nets with pyrethroids chemicals to kill mosquitoes (insecticide-treated net or ITN). In the mid-2000s, world health agencies determined that ITNs should be distributed freely. Since then more than two billion ITNs have been distributed throughout malaria-endemic countries. In regions where fishing is an important economic activity the ITNs have been repurposed for fishing. The …
Using geographic information systems to link population estimates to wastewater surveillance data in New York State, USA
Sewer systems provide many services to communities that have access to them beyond removal of waste and wastewater. Understanding of these systems’ geographic coverage is essential for wastewater-based epidemiology (WBE), which requires accurate estimates for the population contributing wastewater. Reliable estimates for the boundaries of a sewer service area or sewershed can be used to link upstream populations to wastewater samples taken at tre…
Precision public health in schools enabled by wastewater surveillance
Wastewater surveillance provides a cost-effective and non-invasive way to gain an understanding of infectious disease transmission including for COVID-19. We analyzed wastewater samples from one school site in Jefferson County, New York during the 2021–2022 school year. We tested for SARS-CoV-2 RNA once weekly and compared those results with the clinical COVID-19 cases in the school. The amount of SARS-CoV-2 RNA correlated with the number of inci…
Non-detection of emerging and re-emerging pathogens in wastewater surveillance to confirm absence of transmission risk
Infectious disease surveillance systems, including wastewater surveillance, can alert communities to the threat of emerging pathogens. We need methods to infer understanding of transmission dynamics from non-detection. We estimate a sensitivity of detection of poliovirus in wastewater to inform the sensitivity of wastewater surveillance for poliovirus using both a clinical epidemiology and fecal shedding approach. We then apply freedom from disea…
A geo-enabled digital tool for microplanning and delivery of indoor residual spray in Zambia
Indoor residual spraying (IRS) is a vector control tool recommended by the WHO in areas of high malaria burden. Effective IRS implementation is complicated when up-to-date and accurate counts of structures eligible for IRS are unavailable; resultingly, programmatic spray coverage is typically calculated as the proportion of found structures that are sprayed. From 2016 – 2020 in Zambia, an open-source tool termed “Reveal,” was used to support digi…
How local health departments use wastewater surveillance data for public health planning and intervention in New York State
Wastewater surveillance presents a novel data stream for local health departments to understand infectious disease risk in their communities. We conducted a survey of local health departments in New York State regarding their knowledge, attitudes, and practices toward wastewater surveillance of SARS-CoV-2. We further conducted in-depth interviews with a number of local health departments to identify specific use cases of wastewater surveillance d…
Medicine (10 obras) · Environmental health (8 obras) · Environmental Engineering (5 obras) · Geography (5 obras) · Nursing (5 obras) · SARS-CoV-2 detection and testing (5 obras) · Virology (5 obras) · Wastewater (5 obras) · Biology (4 obras) · Biosensors and Analytical Detection (4 obras)