D Carleton Gajdusek
Datos Biográficos
| ID | 3758161 |
|---|---|
| NOMBRE | D Carleton Gajdusek |
| NOMBRES | D Carleton |
| APELLIDO | Gajdusek |
| FIRMA | GAJDUSEK D C |
| AFILIACIONES | National Institutes of Health |
| VERIFICADO | No |
| TOTAL DE OBRAS | 23 |
| TOTAL DE CITAS | 108 |
| TOTAL COMO AUTOR | 23 |
| TOTAL COMO EDITOR | 0 |
| PRIMER AÑO DE PUBLICACIÓN | 1953 |
| AÑO MÁS RECIENTE DE PUBLICACIÓN | 1990 |
| ÍNDICE H | 7 |
Human T‐lymphotropic virus type I
Human T‐cell lymphotropic virus type I (HTLV‐I), the first human retrovirus to be isolated, is the cause of endemic tropical spastic paraparesis (TSP). Originally, this chronic neurological disorder was described as a disease seen among blacks of low socioeconomic status living in tropical countries, and thus for many decades TSP remained a little known curiosity outside the endemic regions. The link between HTLV‐I infection and TSP was made fort…
High prevalence of human T‐lymphotropic virus type I infection in isolated populations of the Western Pacific region confirmed by Western immunoblot
High prevalences of antibodies against human T‐lymphotropic virus type I (HTLV‐I), as confirmed by Western immunoblot, were found in several remote indigenous populations of the Solomon Islands and Vanuatu and in some isolated populations of New Guinea that had no contact with Japanese or Africans and little contact with Caucasians prior to our bleedings. By contrast, zero or very low prevalences of HTLV‐I infection were found in Guamanians and C…
Raymond Pearl memorial lecture, 1989
Sexually transmitted diseases newly introduced into diverse primitive and isolated populations have behaved differently in clinical severity and seriousness of the epidemics they have caused, because of culturally different sexual practices. Epidemic interstitial plasma cell pneumonia in the 1930s–1950s in eastern and northern Europe, caused by Pneumocystis carinii and accompanied by cytomegalovirus infection, was an unexpected AIDS‐like epidemic…
Bone mass in Guamanian patients with amyotrophic lateral sclerosis and parkinsonism‐dementia
Bone mass, as assessed by measurements of total subperiosteal diameter and medullary width of the second metacarpal bone on hand‐wrist radiographs, was evaluated for 31 Guamanian patients (15 males, 16 females) with amyotrophic lateral sclerosis (ALS), 67 patients (39 males, 28 females) with parkinsonism‐dementia (PD), and 66 (34 males, 32 females) nonaffected Guamanian controls. Comparisons between the two disease groups and between each disease…
Population distribution of the human vitamin D binding protein
The polymorphism of the serum vitamin D binding protein (DBP) in humans is based on the existence of three common alleles, Gc 1F , Gc 1S , and Gc 2 , and 84 rare alleles. The geographical distribution of Gc 1F , Gc 1S , and Gc 2 alleles shows north to south clines, together with a balanced equilibrium between the Gc 1F or Gc 1S allele frequency and the Gc 2 frequency. The distribution of the F ST values shows high variability within a geographica…
A population genetic study of the Banks and Torres Islands (Vanuatu) and of the Santa Cruz Islands and polynesian outliers (Solomon Islands)
As part of a multidisciplinary survey of populations in the Banks and Torres Islands of Vanuatu and the Southern and Central Districts of the Solomon Islands, nearly 2,400 persons have been tested for ABO blood groups and a number of serum protein and red cell enzyme genetic marker systems. For the ABO system, the populations are characterized in general by high gene O and low gene B frequencies except in two of the Polynesian Outlier Islands, Re…
Cortical bone loss and measurements of the second metacarpal bone. I. Comparisons between adult Guamanian Chamorros and American caucasians
The amount of radiographically detectable cortical bone, as determined by measurements of the second metacarpal, was evaluated in 42 male and 45 female Guamanian Chamorros and compared with the degree of bony demineralization in U.S. Caucasians participating in the Baltimore Longitudinal Study on Aging of the Gerontology Research Center. All Chamorros were individually matched to the Caucasian participants for age, sex, and menopause status. Cham…
Genetic differentiation among populations in Western New Guinea
Red cell antigen, serum protein and red cell enzyme groups were determined for a series of 1,821 individuals belonging to six language families in Western New Guinea. Three of the language families represent groupings of languages spoken by people in the swampy coastal plain of south central Western New Guinea, two belong to the Central Highlands and one to the Lake Plain area near the confluence of the Idenburg and Rouffaer Rivers. The distribut…
Genetic structure and heterozygosity in the kuru region, Eastern Highlands of New Guinea
Genetic structure of 20 of the 37 linguistic groups in the Eastern Highlands of New Guinea including the kuru region is analyzed using information on blood groups and serum protein polymorphisms. The average individual is heterozygous at 28.6% of loci and the average number of alleles per locus is 1.234. Coefficients of kinship for linguistic groups range from 0.005 for the sweet potato cultivating North Fore to 0.075 for the isolated Pawaians wh…
The dermatoglyphics of the Elema people from the Gulf district of Papua New Guinea
The present report deals with the digital and palmar dermatoglyphics of the Elema peoples from the Gulf District of Papua New Guinea. The samples involved 91 males and 134 females from the areas of Iokea, Sepoe and Karama. The Elema dermatoglyphics, compared to those of other peoples in New Guinea, were found to have a high pattern intensity index and frequency of whorls, and the highest frequency of ulnar type C line, complete simian creases and…
Genetic studies in Paraguay
Genetic studies of 540 Paraguayan Indians from nine tribal groups and 51 Mennonites are presented for ABO, MNSs, P 1 , Rh, Kell, Lewis, Duffy, Diego; for serum immunoglobulins and haptoglobins, G6PD‐deficiency, and thalassemia trait. Group O gene frequencies for all Indian groups were 1.00; for r (cde) , 0.00. Tapiete, Lengua, Toba, and Sanapana R z ( CDE ) frequencies were among the highest ever reported. N frequencies were high for Ache Kwera (…
Blood group, serum protein and red cell enzyme groups of Amerindian populations in Colombia
Red cell samples from persons belonging to four Amerindian linguistic groups in Colombia were investigated for genetic variants in eight blood group systems: for three of the groups investigations were extended to ten red cell enzyme and four serum protein systems. The groups studied are the Noanama (including six Empera) of the Rio Siquirisua and Rio Docampado on the Pacific lowlands and the Cofan, Ingano and Siona Indians of the Upper Rio Putum…
Dermatoglyphics of the Micronesians from the Outer Islands of Yap
Blood group genetic variations in inhabitants of West New Guinea, with a map of the villages and linguistic groups of South West New Guinea
The paper reports the blood group genetic variations found in 1479 individuals, mainly of 17 cultural and linguistic groups, in the ABO, MNS and Rh blood group system. The blood samples consisted of 913 from groups in the south, 422 from the Central Highlands region, and 144 from the northeastern part of the country near Lake Sentani and the Cyclops Mountains. The results of all surveys in West New Guinea in which the ABO, MNS and Rh blood groups…
Blood Group Genetic Data From the Maprik Area of the Sepik District, New Guinea
Haptoglobins and transferrins in Melanesia
This paper reports haptoglobin and transferrin typping of 2687 serum specimens from Melanesians of New Guinea and New Britain. The specimens were obtained from members of 27 different cultural and linguistic groups residing in over 100 different villages in six different administrative districts. They were divided among the Districts as follows: New Britain 821, Sepik 623, Morobe 349, Eastern Highlands 613, Southern Highlands 222, and Western Hig…
Blood Group Genetic Variations in Natives of the Caroline Islands and in Other Parts of Micronesia
Blood group gene frequencies in natives of Cape Gloucester, Western New Britain, and the Gazelle Peninsula, Eastern New Britain
Aging Medicine is an open access journal for international collaboration in multiple research disciplines across the aging sciences. The American Journal of Biological Anthropology is a physical anthropology publication, accepting evolutionary articles in bioarcheology, human & primate biology, & more
Distribution pattern, population genetics and anthropological significance of thalassemia and abnormal hemoglobins in Melanesia
A blood group genetical survey in New Britain
A blood group genetical survey in Australian aboriginal children of the Cape York Peninsula
Hemorrhagic Fevers in Asia
The Sierra Tarahumara
Genetic studies in Paraguay
Genetic studies of 540 Paraguayan Indians from nine tribal groups and 51 Mennonites are presented for ABO, MNSs, P 1 , Rh, Kell, Lewis, Duffy, Diego; for serum immunoglobulins and haptoglobins, G6PD‐deficiency, and thalassemia trait. Group O gene frequencies for all Indian groups were 1.00; for r (cde) , 0.00. Tapiete, Lengua, Toba, and Sanapana R z ( CDE ) frequencies were among the highest ever reported. N frequencies were high for Ache Kwera (…
Genetic differentiation among populations in Western New Guinea
Red cell antigen, serum protein and red cell enzyme groups were determined for a series of 1,821 individuals belonging to six language families in Western New Guinea. Three of the language families represent groupings of languages spoken by people in the swampy coastal plain of south central Western New Guinea, two belong to the Central Highlands and one to the Lake Plain area near the confluence of the Idenburg and Rouffaer Rivers. The distribut…
Distribution pattern, population genetics and anthropological significance of thalassemia and abnormal hemoglobins in Melanesia
Cortical bone loss and measurements of the second metacarpal bone. I. Comparisons between adult Guamanian Chamorros and American caucasians
The amount of radiographically detectable cortical bone, as determined by measurements of the second metacarpal, was evaluated in 42 male and 45 female Guamanian Chamorros and compared with the degree of bony demineralization in U.S. Caucasians participating in the Baltimore Longitudinal Study on Aging of the Gerontology Research Center. All Chamorros were individually matched to the Caucasian participants for age, sex, and menopause status. Cham…
A blood group genetical survey in New Britain
Population distribution of the human vitamin D binding protein
The polymorphism of the serum vitamin D binding protein (DBP) in humans is based on the existence of three common alleles, Gc 1F , Gc 1S , and Gc 2 , and 84 rare alleles. The geographical distribution of Gc 1F , Gc 1S , and Gc 2 alleles shows north to south clines, together with a balanced equilibrium between the Gc 1F or Gc 1S allele frequency and the Gc 2 frequency. The distribution of the F ST values shows high variability within a geographica…
Haptoglobins and transferrins in Melanesia
This paper reports haptoglobin and transferrin typping of 2687 serum specimens from Melanesians of New Guinea and New Britain. The specimens were obtained from members of 27 different cultural and linguistic groups residing in over 100 different villages in six different administrative districts. They were divided among the Districts as follows: New Britain 821, Sepik 623, Morobe 349, Eastern Highlands 613, Southern Highlands 222, and Western Hig…
A blood group genetical survey in Australian aboriginal children of the Cape York Peninsula
Blood Group Genetic Variations in Natives of the Caroline Islands and in Other Parts of Micronesia
Blood group, serum protein and red cell enzyme groups of Amerindian populations in Colombia
Red cell samples from persons belonging to four Amerindian linguistic groups in Colombia were investigated for genetic variants in eight blood group systems: for three of the groups investigations were extended to ten red cell enzyme and four serum protein systems. The groups studied are the Noanama (including six Empera) of the Rio Siquirisua and Rio Docampado on the Pacific lowlands and the Cofan, Ingano and Siona Indians of the Upper Rio Putum…
Blood group gene frequencies in natives of Cape Gloucester, Western New Britain, and the Gazelle Peninsula, Eastern New Britain
Aging Medicine is an open access journal for international collaboration in multiple research disciplines across the aging sciences. The American Journal of Biological Anthropology is a physical anthropology publication, accepting evolutionary articles in bioarcheology, human & primate biology, & more
The Sierra Tarahumara
Blood group genetic variations in inhabitants of West New Guinea, with a map of the villages and linguistic groups of South West New Guinea
The paper reports the blood group genetic variations found in 1479 individuals, mainly of 17 cultural and linguistic groups, in the ABO, MNS and Rh blood group system. The blood samples consisted of 913 from groups in the south, 422 from the Central Highlands region, and 144 from the northeastern part of the country near Lake Sentani and the Cyclops Mountains. The results of all surveys in West New Guinea in which the ABO, MNS and Rh blood groups…
Bone mass in Guamanian patients with amyotrophic lateral sclerosis and parkinsonism‐dementia
Bone mass, as assessed by measurements of total subperiosteal diameter and medullary width of the second metacarpal bone on hand‐wrist radiographs, was evaluated for 31 Guamanian patients (15 males, 16 females) with amyotrophic lateral sclerosis (ALS), 67 patients (39 males, 28 females) with parkinsonism‐dementia (PD), and 66 (34 males, 32 females) nonaffected Guamanian controls. Comparisons between the two disease groups and between each disease…
Genetic structure and heterozygosity in the kuru region, Eastern Highlands of New Guinea
Genetic structure of 20 of the 37 linguistic groups in the Eastern Highlands of New Guinea including the kuru region is analyzed using information on blood groups and serum protein polymorphisms. The average individual is heterozygous at 28.6% of loci and the average number of alleles per locus is 1.234. Coefficients of kinship for linguistic groups range from 0.005 for the sweet potato cultivating North Fore to 0.075 for the isolated Pawaians wh…
The dermatoglyphics of the Elema people from the Gulf district of Papua New Guinea
The present report deals with the digital and palmar dermatoglyphics of the Elema peoples from the Gulf District of Papua New Guinea. The samples involved 91 males and 134 females from the areas of Iokea, Sepoe and Karama. The Elema dermatoglyphics, compared to those of other peoples in New Guinea, were found to have a high pattern intensity index and frequency of whorls, and the highest frequency of ulnar type C line, complete simian creases and…
The Sierra Tarahumara
Hemorrhagic Fevers in Asia
A blood group genetical survey in Australian aboriginal children of the Cape York Peninsula
A blood group genetical survey in New Britain
Distribution pattern, population genetics and anthropological significance of thalassemia and abnormal hemoglobins in Melanesia
Blood group gene frequencies in natives of Cape Gloucester, Western New Britain, and the Gazelle Peninsula, Eastern New Britain
Aging Medicine is an open access journal for international collaboration in multiple research disciplines across the aging sciences. The American Journal of Biological Anthropology is a physical anthropology publication, accepting evolutionary articles in bioarcheology, human & primate biology, & more
Blood Group Genetic Data From the Maprik Area of the Sepik District, New Guinea
Haptoglobins and transferrins in Melanesia
This paper reports haptoglobin and transferrin typping of 2687 serum specimens from Melanesians of New Guinea and New Britain. The specimens were obtained from members of 27 different cultural and linguistic groups residing in over 100 different villages in six different administrative districts. They were divided among the Districts as follows: New Britain 821, Sepik 623, Morobe 349, Eastern Highlands 613, Southern Highlands 222, and Western Hig…
Blood Group Genetic Variations in Natives of the Caroline Islands and in Other Parts of Micronesia
Blood group genetic variations in inhabitants of West New Guinea, with a map of the villages and linguistic groups of South West New Guinea
The paper reports the blood group genetic variations found in 1479 individuals, mainly of 17 cultural and linguistic groups, in the ABO, MNS and Rh blood group system. The blood samples consisted of 913 from groups in the south, 422 from the Central Highlands region, and 144 from the northeastern part of the country near Lake Sentani and the Cyclops Mountains. The results of all surveys in West New Guinea in which the ABO, MNS and Rh blood groups…
Dermatoglyphics of the Micronesians from the Outer Islands of Yap
Genetic studies in Paraguay
Genetic studies of 540 Paraguayan Indians from nine tribal groups and 51 Mennonites are presented for ABO, MNSs, P 1 , Rh, Kell, Lewis, Duffy, Diego; for serum immunoglobulins and haptoglobins, G6PD‐deficiency, and thalassemia trait. Group O gene frequencies for all Indian groups were 1.00; for r (cde) , 0.00. Tapiete, Lengua, Toba, and Sanapana R z ( CDE ) frequencies were among the highest ever reported. N frequencies were high for Ache Kwera (…
Blood group, serum protein and red cell enzyme groups of Amerindian populations in Colombia
Red cell samples from persons belonging to four Amerindian linguistic groups in Colombia were investigated for genetic variants in eight blood group systems: for three of the groups investigations were extended to ten red cell enzyme and four serum protein systems. The groups studied are the Noanama (including six Empera) of the Rio Siquirisua and Rio Docampado on the Pacific lowlands and the Cofan, Ingano and Siona Indians of the Upper Rio Putum…
The dermatoglyphics of the Elema people from the Gulf district of Papua New Guinea
The present report deals with the digital and palmar dermatoglyphics of the Elema peoples from the Gulf District of Papua New Guinea. The samples involved 91 males and 134 females from the areas of Iokea, Sepoe and Karama. The Elema dermatoglyphics, compared to those of other peoples in New Guinea, were found to have a high pattern intensity index and frequency of whorls, and the highest frequency of ulnar type C line, complete simian creases and…
Genetic structure and heterozygosity in the kuru region, Eastern Highlands of New Guinea
Genetic structure of 20 of the 37 linguistic groups in the Eastern Highlands of New Guinea including the kuru region is analyzed using information on blood groups and serum protein polymorphisms. The average individual is heterozygous at 28.6% of loci and the average number of alleles per locus is 1.234. Coefficients of kinship for linguistic groups range from 0.005 for the sweet potato cultivating North Fore to 0.075 for the isolated Pawaians wh…
Genetic differentiation among populations in Western New Guinea
Red cell antigen, serum protein and red cell enzyme groups were determined for a series of 1,821 individuals belonging to six language families in Western New Guinea. Three of the language families represent groupings of languages spoken by people in the swampy coastal plain of south central Western New Guinea, two belong to the Central Highlands and one to the Lake Plain area near the confluence of the Idenburg and Rouffaer Rivers. The distribut…
Cortical bone loss and measurements of the second metacarpal bone. I. Comparisons between adult Guamanian Chamorros and American caucasians
The amount of radiographically detectable cortical bone, as determined by measurements of the second metacarpal, was evaluated in 42 male and 45 female Guamanian Chamorros and compared with the degree of bony demineralization in U.S. Caucasians participating in the Baltimore Longitudinal Study on Aging of the Gerontology Research Center. All Chamorros were individually matched to the Caucasian participants for age, sex, and menopause status. Cham…
A population genetic study of the Banks and Torres Islands (Vanuatu) and of the Santa Cruz Islands and polynesian outliers (Solomon Islands)
As part of a multidisciplinary survey of populations in the Banks and Torres Islands of Vanuatu and the Southern and Central Districts of the Solomon Islands, nearly 2,400 persons have been tested for ABO blood groups and a number of serum protein and red cell enzyme genetic marker systems. For the ABO system, the populations are characterized in general by high gene O and low gene B frequencies except in two of the Polynesian Outlier Islands, Re…
Population distribution of the human vitamin D binding protein
The polymorphism of the serum vitamin D binding protein (DBP) in humans is based on the existence of three common alleles, Gc 1F , Gc 1S , and Gc 2 , and 84 rare alleles. The geographical distribution of Gc 1F , Gc 1S , and Gc 2 alleles shows north to south clines, together with a balanced equilibrium between the Gc 1F or Gc 1S allele frequency and the Gc 2 frequency. The distribution of the F ST values shows high variability within a geographica…
Bone mass in Guamanian patients with amyotrophic lateral sclerosis and parkinsonism‐dementia
Bone mass, as assessed by measurements of total subperiosteal diameter and medullary width of the second metacarpal bone on hand‐wrist radiographs, was evaluated for 31 Guamanian patients (15 males, 16 females) with amyotrophic lateral sclerosis (ALS), 67 patients (39 males, 28 females) with parkinsonism‐dementia (PD), and 66 (34 males, 32 females) nonaffected Guamanian controls. Comparisons between the two disease groups and between each disease…
Human T‐lymphotropic virus type I
Human T‐cell lymphotropic virus type I (HTLV‐I), the first human retrovirus to be isolated, is the cause of endemic tropical spastic paraparesis (TSP). Originally, this chronic neurological disorder was described as a disease seen among blacks of low socioeconomic status living in tropical countries, and thus for many decades TSP remained a little known curiosity outside the endemic regions. The link between HTLV‐I infection and TSP was made fort…
High prevalence of human T‐lymphotropic virus type I infection in isolated populations of the Western Pacific region confirmed by Western immunoblot
High prevalences of antibodies against human T‐lymphotropic virus type I (HTLV‐I), as confirmed by Western immunoblot, were found in several remote indigenous populations of the Solomon Islands and Vanuatu and in some isolated populations of New Guinea that had no contact with Japanese or Africans and little contact with Caucasians prior to our bleedings. By contrast, zero or very low prevalences of HTLV‐I infection were found in Guamanians and C…
Raymond Pearl memorial lecture, 1989
Sexually transmitted diseases newly introduced into diverse primitive and isolated populations have behaved differently in clinical severity and seriousness of the epidemics they have caused, because of culturally different sexual practices. Epidemic interstitial plasma cell pneumonia in the 1930s–1950s in eastern and northern Europe, caused by Pneumocystis carinii and accompanied by cytomegalovirus infection, was an unexpected AIDS‐like epidemic…
Medicine (13 obras) · Geography (11 obras) · Ethnology (9 obras) · Biology (8 obras) · Demography (8 obras) · History (8 obras) · New guinea (7 obras) · Sociology (7 obras) · Archaeology (6 obras) · Immunology (6 obras)