Takafumi Ishida
Datos Biográficos
| ID | 4091343 |
|---|---|
| NOMBRE | Takafumi Ishida |
| NOMBRES | Takafumi |
| APELLIDO | Ishida |
| FIRMA | ISHIDA T |
| AFILIACIONES | The University of Tokyo |
| ORCID | 0000-0002-0896-3069 |
| VERIFICADO | Sí |
| TOTAL DE OBRAS | 23 |
| TOTAL DE CITAS | 10 |
| TOTAL COMO AUTOR | 23 |
| TOTAL COMO EDITOR | 0 |
| PRIMER AÑO DE PUBLICACIÓN | 1995 |
| AÑO MÁS RECIENTE DE PUBLICACIÓN | 2024 |
| ÍNDICE H | 2 |
Reduction of bitter taste receptor gene family in folivorous colobine primates relative to omnivorous cercopithecine primates
Bitter taste perception is important in preventing animals from ingesting potentially toxic compounds. Whole-genome assembly (WGA) data have revealed that bitter taste receptor genes ( TAS2R s) comprise a multigene family with dozens of intact and disrupted genes in primates. However, publicly available WGA data are often incomplete, especially for multigene families. In this study, we employed a targeted capture (TC) approach specifically probin…
Worldwide trends in underweight and obesity from 1990 to 2022
BACKGROUND: Underweight and obesity are associated with adverse health outcomes throughout the life course. We estimated the individual and combined prevalence of underweight or thinness and obesity, and their changes, from 1990 to 2022 for adults and school-aged children and adolescents in 200 countries and territories. METHODS: ). For school-aged children and adolescents, we report thinness (BMI 2 SD above the median). FINDINGS: From 1990 to 20…
Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019
BACKGROUND: Hypertension can be detected at the primary health-care level and low-cost treatments can effectively control hypertension. We aimed to measure the prevalence of hypertension and progress in its detection, treatment, and control from 1990 to 2019 for 200 countries and territories. METHODS: We used data from 1990 to 2019 on people aged 30-79 years from population-representative studies with measurement of blood pressure and data on blo…
Height and body-mass index trajectories of school-aged children and adolescents from 1985 to 2019 in 200 countries and territories
BACKGROUND: Comparable global data on health and nutrition of school-aged children and adolescents are scarce. We aimed to estimate age trajectories and time trends in mean height and mean body-mass index (BMI), which measures weight gain beyond what is expected from height gain, for school-aged children and adolescents. METHODS: For this pooled analysis, we used a database of cardiometabolic risk factors collated by the Non-Communicable Disease …
Rising rural body-mass index is the main driver of the global obesity epidemic in adults
Body-mass index (BMI) has increased steadily in most countries in parallel with a rise in the proportion of the population who live in cities 1,2 . This has led to a widely reported view that urbanization is one of the most important drivers of the global rise in obesity 3–6 . Here we use 2,009 population-based studies, with measurements of height and weight in more than 112 million adults, to report national, regional and global trends in mean B…
Molecular evolution of the semenogelin 1 and 2 and mating system in gibbons
Objectives Semenogelin 1 and 2 (SEMG1 and SEMG2) are known as semen coagulating proteins in primates with a repetitive structure of 60‐amino acids. The number of repeats varies among species and is hypothesized to be related to the level of primate sperm competition. Gibbons until recently were thought to be monogamous primates, but it is now known that gibbon social structure is flexible. Thus, hypotheses of the relationship between the SEMG s e…
Association study of CREBRF missense variant (rs373863828
The rs373863828-A allele may not directly affect the level of serum HDL-cholesterol independent of BMI. To confirm the present findings, association studies with large sample sizes and functional analyses are required
The presence of females induces elevated cortisol levels in an alpha male
OBJECTIVES: In group-living primates, it has been reported that the alpha male exhibits high concentrations of cortisol and testosterone in the context of mating competition. We investigated how the presence of females affected salivary cortisol and testosterone levels in males from a small captive group of chimpanzees (Pan troglodytes). Specifically, we assessed whether the presence of females resulted in a rapid increase in salivary cortisol an…
Short dispersal distance of males in a wild white‐handed gibbon ( Hylobates lar ) population
OBJECTIVES: It has long been recognized that in gibbons both sexes disperse from the natal group. However, the fate of dispersed individuals was rarely documented. Here we provide the first detailed information on sex differences in dispersal patterns by analyzing the spatial genetic structure of a well-known white-handed gibbon (Hylobates lar) population. MATERIALS AND METHODS: Mitochondrial DNA (mtDNA) and Y-chromosomal haplotypes, and autosoma…
Molecular evidence for the introgression between Hylobates lar and H. pileatus in the wild
Extra‐pair paternity confirmed in wild white‐handed gibbons
Knowledge of the genetic mating system of animal species is essential for our understanding of the evolution of social systems and individual reproductive strategies. In recent years, genetic methods have uncovered an unexpected diversity of paternal genetic contributions across diverse animal social mating systems, but particularly in pair-living species. In most pair-living birds, for example, genetic and behavioral observations have confirmed …
DRD4 VNTR polymorphism in Oceanic populations
To study the origin of Polynesians and the gene flow from Polynesian ancestors to indigenous Melanesians, a 48-bp variable number of tandem repeats (VNTR) in exon 3 of the dopamine D4 receptor (DRD4) gene was investigated for six Austronesian (AN)-speaking populations—two in Tonga (Nuku’alofa and Ha’apai), three in Solomon Islands (Munda, Paradise, and Rawaki, of whom Rawaki was a Micronesian migrant group), and one in Papua New Guinea (Balopa), …
The serum leptin level and body mass index in Melanesian and Micronesian Solomon Islanders
Objectives: This study examined the association between the serum leptin level and body mass index (BMI) and the effects of urbanization and polymorphisms of leptin ( LEP ) or leptin receptor ( LEPR ) genes on the leptin level in three Solomon Islands populations. Methods: A Melanesian population living in a remote area (participants: 106 males and 106 females, ages: 18–74 years), a Melanesian population in an urban area (89 and 94, 18–79 years),…
Validation of salivary cortisol and testosterone assays in chimpanzees by liquid chromatography‐tandem mass spectrometry
Owing to its high temporal sensitivity, saliva has distinct advantages for measuring steroids, compared with other noninvasive samples such as urine and feces. Here, we report the validity of assaying salivary cortisol (C) and testosterone (T) using liquid chromatography‐tandem mass spectrometry (LC‐MS/MS) in captive male chimpanzees, Pan troglodytes . For both the C and T concentrations, we found positive relationships between saliva and plasma.…
The Pacific lineage (2E) of JC polyomavirus is prevalent in Sumba Island, Eastern Indonesia
Recent studies have identified a Pacific lineage (2E) of JC polyomavirus (also designated as JC virus or JCV) that occurs in both Island Southeast Asia and Oceania, but not in mainland Asia. It has been postulated that this lineage traveled with Austronesian-speaking people who are now spread throughout Island Southeast Asia and Oceania (excluding Australia and inland and southern New Guinea). However, to date, the 2E lineage has been identified …
Variation of the melanocortin 1 receptor gene in the macaques
Melanocortin 1 receptor (MC1R), a G‐coupled seven‐transmembrane receptor protein, plays a key role in the regulation of melanin synthesis in mammals. Sequence variation of the MC1R gene ( MC1R ) has been associated with pigmentation phenotypes in humans and in several animal species. The macaques (genus Macaca ) are known to show a marked inter‐specific variation in coat color although the causative genetic variation remains unclear. We investiga…
Ovalocytosis without band 3 gene 27-bp deletion and malaria infection
Genetic adaptation to malaria is a longstanding research topic in anthropology and human genetics. Southeast Asian ovalocytosis (SAO) has been documented to have resistance to malaria; however, the implications of existing data are controversial. In particular, SAO resistance to malaria is unlcear in terms of the types of SAO, with/without the 27-base pair deletion in the band 3 gene (B3Δ27). To shed light on the relationships between SAO and mal…
Serological Survey for the Infection of Hepatitis B Virus, Hepatitis C Virus, Human Immunodeficiency Virus and Human T-Lymphotropic Virus-1 among Isolated Ethnic Groups in Nepal
Serological survey for the infection of hepatitis B virus (HBV), hepatitis C virus (HCV), human immunodeficiency virus (HIV) and human T-lymphotropic virus-1 (HTLV-1) among isolated ethnic groups in Nepal was done. Altogether 262 plasmas collected from the Raute in West Nepal, Chepang in Middle Nepal and Munda in East Nepal were tested. Plasmas were tested for the presence of HBV surface antigen (HBVs), antibodies to HBVs, HCV, HIV and HTLV-1 by …
Human mtDNA and Y-chromosome variation is correlated with matrilocal versus patrilocal residence
Population Genetic Studies on Nine Aboriginal Ethnic Groups of Taiwan. II. Serum Protein Systems
As part of our comprehensive genetic study of the aboriginal Taiwanese (Gaoshan), we have reported the distribution of allele frequencies for 13 red cell enzyme and 4 serum protein polymorphisms in all nine aboriginal groups. In this study, 10 additional serum protein polymorphisms for AHSG, C3, C6, C7, GC, HP, ITIH1, PI, TF and ZAG were typed. Common and variant alleles prevailing in East Asian populations were found together with several new va…
Genetic Study of the Paleolithic and Neolithic Southeast Asians
DNA samples were extracted from six prehistoric human remains, found on the Malay Peninsula, dating to the Paleolithic and the Neolithic periods. Nucleotide sequences of mitochondrial DNA were determined by the polymerase chain reaction-direct sequencing method. A phylogenetic tree between prehistoric and present humans was constructed based on the nucleotide sequence data. Mitochondrial DNA phylogenetic relationships and ethnoarchaeological evid…
Fluorescence in situ hybridization establishes homology between human and silvered leaf monkey chromosomes, reveals reciprocal translocations between chromosomes homologous to human Y/5, 1/9, and 6/16…
We employed in situ hybridization of chromosome-specific DNA probes ("chromosome painting") of all human chromosomes to establish homologies between the human and the silvered lead monkey karyotypes (Presbytis cristata 2n = 44). The 24 human paints gave 30 signals on the haploid female chromosome set and 34 signals on the haploid male chromosome set. This difference is due to a reciprocal translocation between the Y and an autosome homologous to …
Genetic Polymorphism of ADA in Taiwan Aboriginal Populations
ADA subtype polymorphism in nine aboriginal populations (Gaoshan) of Taiwan was studied by means of the IEF method. A new ADA variant allele, ADA*Taiwan1, was in a high allele frequency in two Gaoshan populations, the Amis and the Paiwans. Another new variant, ADA*Taiwan2, was found in only one case of heterozygote in the Saisiats. Allele frequencies of a common allele, ADA*2, in the Paiwans and the Amis were the highest among the Asian populatio…
Genetic Study of the Paleolithic and Neolithic Southeast Asians
DNA samples were extracted from six prehistoric human remains, found on the Malay Peninsula, dating to the Paleolithic and the Neolithic periods. Nucleotide sequences of mitochondrial DNA were determined by the polymerase chain reaction-direct sequencing method. A phylogenetic tree between prehistoric and present humans was constructed based on the nucleotide sequence data. Mitochondrial DNA phylogenetic relationships and ethnoarchaeological evid…
Short dispersal distance of males in a wild white‐handed gibbon ( Hylobates lar ) population
OBJECTIVES: It has long been recognized that in gibbons both sexes disperse from the natal group. However, the fate of dispersed individuals was rarely documented. Here we provide the first detailed information on sex differences in dispersal patterns by analyzing the spatial genetic structure of a well-known white-handed gibbon (Hylobates lar) population. MATERIALS AND METHODS: Mitochondrial DNA (mtDNA) and Y-chromosomal haplotypes, and autosoma…
Population Genetic Studies on Nine Aboriginal Ethnic Groups of Taiwan. II. Serum Protein Systems
As part of our comprehensive genetic study of the aboriginal Taiwanese (Gaoshan), we have reported the distribution of allele frequencies for 13 red cell enzyme and 4 serum protein polymorphisms in all nine aboriginal groups. In this study, 10 additional serum protein polymorphisms for AHSG, C3, C6, C7, GC, HP, ITIH1, PI, TF and ZAG were typed. Common and variant alleles prevailing in East Asian populations were found together with several new va…
Genetic Polymorphism of ADA in Taiwan Aboriginal Populations
ADA subtype polymorphism in nine aboriginal populations (Gaoshan) of Taiwan was studied by means of the IEF method. A new ADA variant allele, ADA*Taiwan1, was in a high allele frequency in two Gaoshan populations, the Amis and the Paiwans. Another new variant, ADA*Taiwan2, was found in only one case of heterozygote in the Saisiats. Allele frequencies of a common allele, ADA*2, in the Paiwans and the Amis were the highest among the Asian populatio…
Fluorescence in situ hybridization establishes homology between human and silvered leaf monkey chromosomes, reveals reciprocal translocations between chromosomes homologous to human Y/5, 1/9, and 6/16…
We employed in situ hybridization of chromosome-specific DNA probes ("chromosome painting") of all human chromosomes to establish homologies between the human and the silvered lead monkey karyotypes (Presbytis cristata 2n = 44). The 24 human paints gave 30 signals on the haploid female chromosome set and 34 signals on the haploid male chromosome set. This difference is due to a reciprocal translocation between the Y and an autosome homologous to …
Human mtDNA and Y-chromosome variation is correlated with matrilocal versus patrilocal residence
Population Genetic Studies on Nine Aboriginal Ethnic Groups of Taiwan. II. Serum Protein Systems
As part of our comprehensive genetic study of the aboriginal Taiwanese (Gaoshan), we have reported the distribution of allele frequencies for 13 red cell enzyme and 4 serum protein polymorphisms in all nine aboriginal groups. In this study, 10 additional serum protein polymorphisms for AHSG, C3, C6, C7, GC, HP, ITIH1, PI, TF and ZAG were typed. Common and variant alleles prevailing in East Asian populations were found together with several new va…
Genetic Study of the Paleolithic and Neolithic Southeast Asians
DNA samples were extracted from six prehistoric human remains, found on the Malay Peninsula, dating to the Paleolithic and the Neolithic periods. Nucleotide sequences of mitochondrial DNA were determined by the polymerase chain reaction-direct sequencing method. A phylogenetic tree between prehistoric and present humans was constructed based on the nucleotide sequence data. Mitochondrial DNA phylogenetic relationships and ethnoarchaeological evid…
Serological Survey for the Infection of Hepatitis B Virus, Hepatitis C Virus, Human Immunodeficiency Virus and Human T-Lymphotropic Virus-1 among Isolated Ethnic Groups in Nepal
Serological survey for the infection of hepatitis B virus (HBV), hepatitis C virus (HCV), human immunodeficiency virus (HIV) and human T-lymphotropic virus-1 (HTLV-1) among isolated ethnic groups in Nepal was done. Altogether 262 plasmas collected from the Raute in West Nepal, Chepang in Middle Nepal and Munda in East Nepal were tested. Plasmas were tested for the presence of HBV surface antigen (HBVs), antibodies to HBVs, HCV, HIV and HTLV-1 by …
Ovalocytosis without band 3 gene 27-bp deletion and malaria infection
Genetic adaptation to malaria is a longstanding research topic in anthropology and human genetics. Southeast Asian ovalocytosis (SAO) has been documented to have resistance to malaria; however, the implications of existing data are controversial. In particular, SAO resistance to malaria is unlcear in terms of the types of SAO, with/without the 27-base pair deletion in the band 3 gene (B3Δ27). To shed light on the relationships between SAO and mal…
The Pacific lineage (2E) of JC polyomavirus is prevalent in Sumba Island, Eastern Indonesia
Recent studies have identified a Pacific lineage (2E) of JC polyomavirus (also designated as JC virus or JCV) that occurs in both Island Southeast Asia and Oceania, but not in mainland Asia. It has been postulated that this lineage traveled with Austronesian-speaking people who are now spread throughout Island Southeast Asia and Oceania (excluding Australia and inland and southern New Guinea). However, to date, the 2E lineage has been identified …
Variation of the melanocortin 1 receptor gene in the macaques
Melanocortin 1 receptor (MC1R), a G‐coupled seven‐transmembrane receptor protein, plays a key role in the regulation of melanin synthesis in mammals. Sequence variation of the MC1R gene ( MC1R ) has been associated with pigmentation phenotypes in humans and in several animal species. The macaques (genus Macaca ) are known to show a marked inter‐specific variation in coat color although the causative genetic variation remains unclear. We investiga…
Validation of salivary cortisol and testosterone assays in chimpanzees by liquid chromatography‐tandem mass spectrometry
Owing to its high temporal sensitivity, saliva has distinct advantages for measuring steroids, compared with other noninvasive samples such as urine and feces. Here, we report the validity of assaying salivary cortisol (C) and testosterone (T) using liquid chromatography‐tandem mass spectrometry (LC‐MS/MS) in captive male chimpanzees, Pan troglodytes . For both the C and T concentrations, we found positive relationships between saliva and plasma.…
The serum leptin level and body mass index in Melanesian and Micronesian Solomon Islanders
Objectives: This study examined the association between the serum leptin level and body mass index (BMI) and the effects of urbanization and polymorphisms of leptin ( LEP ) or leptin receptor ( LEPR ) genes on the leptin level in three Solomon Islands populations. Methods: A Melanesian population living in a remote area (participants: 106 males and 106 females, ages: 18–74 years), a Melanesian population in an urban area (89 and 94, 18–79 years),…
DRD4 VNTR polymorphism in Oceanic populations
To study the origin of Polynesians and the gene flow from Polynesian ancestors to indigenous Melanesians, a 48-bp variable number of tandem repeats (VNTR) in exon 3 of the dopamine D4 receptor (DRD4) gene was investigated for six Austronesian (AN)-speaking populations—two in Tonga (Nuku’alofa and Ha’apai), three in Solomon Islands (Munda, Paradise, and Rawaki, of whom Rawaki was a Micronesian migrant group), and one in Papua New Guinea (Balopa), …
Molecular evidence for the introgression between Hylobates lar and H. pileatus in the wild
Extra‐pair paternity confirmed in wild white‐handed gibbons
Knowledge of the genetic mating system of animal species is essential for our understanding of the evolution of social systems and individual reproductive strategies. In recent years, genetic methods have uncovered an unexpected diversity of paternal genetic contributions across diverse animal social mating systems, but particularly in pair-living species. In most pair-living birds, for example, genetic and behavioral observations have confirmed …
Association study of CREBRF missense variant (rs373863828
The rs373863828-A allele may not directly affect the level of serum HDL-cholesterol independent of BMI. To confirm the present findings, association studies with large sample sizes and functional analyses are required
The presence of females induces elevated cortisol levels in an alpha male
OBJECTIVES: In group-living primates, it has been reported that the alpha male exhibits high concentrations of cortisol and testosterone in the context of mating competition. We investigated how the presence of females affected salivary cortisol and testosterone levels in males from a small captive group of chimpanzees (Pan troglodytes). Specifically, we assessed whether the presence of females resulted in a rapid increase in salivary cortisol an…
Short dispersal distance of males in a wild white‐handed gibbon ( Hylobates lar ) population
OBJECTIVES: It has long been recognized that in gibbons both sexes disperse from the natal group. However, the fate of dispersed individuals was rarely documented. Here we provide the first detailed information on sex differences in dispersal patterns by analyzing the spatial genetic structure of a well-known white-handed gibbon (Hylobates lar) population. MATERIALS AND METHODS: Mitochondrial DNA (mtDNA) and Y-chromosomal haplotypes, and autosoma…
Rising rural body-mass index is the main driver of the global obesity epidemic in adults
Body-mass index (BMI) has increased steadily in most countries in parallel with a rise in the proportion of the population who live in cities 1,2 . This has led to a widely reported view that urbanization is one of the most important drivers of the global rise in obesity 3–6 . Here we use 2,009 population-based studies, with measurements of height and weight in more than 112 million adults, to report national, regional and global trends in mean B…
Molecular evolution of the semenogelin 1 and 2 and mating system in gibbons
Objectives Semenogelin 1 and 2 (SEMG1 and SEMG2) are known as semen coagulating proteins in primates with a repetitive structure of 60‐amino acids. The number of repeats varies among species and is hypothesized to be related to the level of primate sperm competition. Gibbons until recently were thought to be monogamous primates, but it is now known that gibbon social structure is flexible. Thus, hypotheses of the relationship between the SEMG s e…
Height and body-mass index trajectories of school-aged children and adolescents from 1985 to 2019 in 200 countries and territories
BACKGROUND: Comparable global data on health and nutrition of school-aged children and adolescents are scarce. We aimed to estimate age trajectories and time trends in mean height and mean body-mass index (BMI), which measures weight gain beyond what is expected from height gain, for school-aged children and adolescents. METHODS: For this pooled analysis, we used a database of cardiometabolic risk factors collated by the Non-Communicable Disease …
Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019
BACKGROUND: Hypertension can be detected at the primary health-care level and low-cost treatments can effectively control hypertension. We aimed to measure the prevalence of hypertension and progress in its detection, treatment, and control from 1990 to 2019 for 200 countries and territories. METHODS: We used data from 1990 to 2019 on people aged 30-79 years from population-representative studies with measurement of blood pressure and data on blo…
Reduction of bitter taste receptor gene family in folivorous colobine primates relative to omnivorous cercopithecine primates
Bitter taste perception is important in preventing animals from ingesting potentially toxic compounds. Whole-genome assembly (WGA) data have revealed that bitter taste receptor genes ( TAS2R s) comprise a multigene family with dozens of intact and disrupted genes in primates. However, publicly available WGA data are often incomplete, especially for multigene families. In this study, we employed a targeted capture (TC) approach specifically probin…
Worldwide trends in underweight and obesity from 1990 to 2022
BACKGROUND: Underweight and obesity are associated with adverse health outcomes throughout the life course. We estimated the individual and combined prevalence of underweight or thinness and obesity, and their changes, from 1990 to 2022 for adults and school-aged children and adolescents in 200 countries and territories. METHODS: ). For school-aged children and adolescents, we report thinness (BMI 2 SD above the median). FINDINGS: From 1990 to 20…
Biology (18 obras) · Demography (12 obras) · Gene (11 obras) · Population (11 obras) · Genetics (10 obras) · Medicine (9 obras) · Evolutionary biology (8 obras) · Ecology (6 obras) · Genetics (6 obras) · Primate Behavior and Ecology (6 obras)