David Karasik
Datos Biográficos
| ID | 4182765 |
|---|---|
| NOMBRE | David Karasik |
| NOMBRES | David |
| APELLIDO | Karasik |
| FIRMA | KARASIK D |
| AFILIACIONES | Tel Aviv University |
| ORCID | 0000-0002-8826-0530 |
| VERIFICADO | Sí |
| TOTAL DE OBRAS | 10 |
| TOTAL DE CITAS | 9 |
| TOTAL COMO AUTOR | 10 |
| TOTAL COMO EDITOR | 0 |
| PRIMER AÑO DE PUBLICACIÓN | 1998 |
| AÑO MÁS RECIENTE DE PUBLICACIÓN | 2008 |
| ÍNDICE H | 2 |
A genome wide linkage scan of metacarpal size and geometry in the Framingham Study
Bone geometry is a significant component of bone strength, and has a clinical utility in predicting fractures and quantifying bone loss. Bone geometry is known to have a substantial genetic component. We performed linkage analysis to identify chromosomal regions governing metacarpal bone geometry. A genome‐wide scan (with a set of 615 markers with spacing of ∼5.7 cM) was performed on 1,702 individuals from 330 extended families of the Framingham …
Modelling of age-related bone loss using cross-sectional data
The change of phalangeal BMD with age may be best described by a two-interval function, regardless of sex and ethnic background. However, specific parameter estimates depend both on gender and ethnic affiliation. This study has yielded a well-fitted model of BMD dependence on age suitable for further use in population studies
Evidence on major gene control of cortical index in pedigree data from middle dalmatia, croatia
Age assessment of Natufian remains from the land of Israel
The Natufian population of Israel was first described by Garrod in 1932, and since then hundreds of skeletons have been discovered in archaeological excavations. Their culture is amply discussed in the literature as designating the transitional stage between extractive and productive subsistence economics in the period ca. 13,000-10,000 years BP. The Natufians represent a local population with strong biologic ties to the more ancient Upper Paleol…
Use of the Hand Bones Roentgenographs in the Prediction of Age in Nine Human Populations
The major aim of this study was to develop an accurate method of age prediction for a wide range of ages, based on the roentgenographic assessment of the hand bones, for use in paleoanthropology and forensic medicine. The roentgenographs of the hand bones were assessed in 5756 individuals, 2683 males and 3073 females, aged 17-93 and 17-89, respectively, belonging to 9 ethnic groups from the former USSR, Israel, and Sinai peninsula (Egypt). For ea…
Comparative analysis of age prediction by markers of bone change in the hand assessed by roentgenography
The major aim of this study was to develop an accurate method of age prediction for a wide range of ages based on the roentgenographic assessment of the hand bones. Such a method may be of particular interest in paleoanthropology and forensic medicine. The present paper provides the results of an analysis of individuals belonging to two ethnically different population samples: 1) Chuvasha (the Russian Federation), 293 males and 254 females, aged …
Genes play an important role in bone aging
Pathological changes in bones like osteoarthritis and osteoporosis are among the most frequent outcomes of age and aging. Presently, little is known about the genetic basis of peak bone mass or rate of bone loss, or on the genetics of bone formation and resorption. This paper reviews modern studies, dealing with the genetic aspects of bone formation and bone aging. The currently most popular measures of bone aging are: osteometric measurements (O…
Genes play an important role in bone aging
Pathological changes in bones like osteoarthritis and osteoporosis are among the most frequent outcomes of age and aging. Presently, little is known about the genetic basis of peak bone mass or rate of bone loss, or on the genetics of bone formation and resorption. This paper reviews modern studies, dealing with the genetic aspects of bone formation and bone aging. The currently most popular measures of bone aging are: osteometric measurements (O…
Skeletal Age Assessment of Fossil Hominids
Fluctuating asymmetry and morphometric variation of hand bones
The major aim of this study was to test three hypotheses: 1) more complex traits of the hand are less prone to developmental insults and therefore show lower fluctuating asymmetry (FA) as compared with simple traits; 2) the manifestation of FA correlates with the variability of the trait (i.e., CV); and 3) FA is an organ-wide property, and therefore a concordance exists between the FA measures of different traits in hand bones. Seventy-two bilate…
Skeletal Age Assessment of Fossil Hominids
Use of the Hand Bones Roentgenographs in the Prediction of Age in Nine Human Populations
The major aim of this study was to develop an accurate method of age prediction for a wide range of ages, based on the roentgenographic assessment of the hand bones, for use in paleoanthropology and forensic medicine. The roentgenographs of the hand bones were assessed in 5756 individuals, 2683 males and 3073 females, aged 17-93 and 17-89, respectively, belonging to 9 ethnic groups from the former USSR, Israel, and Sinai peninsula (Egypt). For ea…
Genes play an important role in bone aging
Pathological changes in bones like osteoarthritis and osteoporosis are among the most frequent outcomes of age and aging. Presently, little is known about the genetic basis of peak bone mass or rate of bone loss, or on the genetics of bone formation and resorption. This paper reviews modern studies, dealing with the genetic aspects of bone formation and bone aging. The currently most popular measures of bone aging are: osteometric measurements (O…
Genes play an important role in bone aging
Pathological changes in bones like osteoarthritis and osteoporosis are among the most frequent outcomes of age and aging. Presently, little is known about the genetic basis of peak bone mass or rate of bone loss, or on the genetics of bone formation and resorption. This paper reviews modern studies, dealing with the genetic aspects of bone formation and bone aging. The currently most popular measures of bone aging are: osteometric measurements (O…
Skeletal Age Assessment of Fossil Hominids
Fluctuating asymmetry and morphometric variation of hand bones
The major aim of this study was to test three hypotheses: 1) more complex traits of the hand are less prone to developmental insults and therefore show lower fluctuating asymmetry (FA) as compared with simple traits; 2) the manifestation of FA correlates with the variability of the trait (i.e., CV); and 3) FA is an organ-wide property, and therefore a concordance exists between the FA measures of different traits in hand bones. Seventy-two bilate…
Comparative analysis of age prediction by markers of bone change in the hand assessed by roentgenography
The major aim of this study was to develop an accurate method of age prediction for a wide range of ages based on the roentgenographic assessment of the hand bones. Such a method may be of particular interest in paleoanthropology and forensic medicine. The present paper provides the results of an analysis of individuals belonging to two ethnically different population samples: 1) Chuvasha (the Russian Federation), 293 males and 254 females, aged …
Age assessment of Natufian remains from the land of Israel
The Natufian population of Israel was first described by Garrod in 1932, and since then hundreds of skeletons have been discovered in archaeological excavations. Their culture is amply discussed in the literature as designating the transitional stage between extractive and productive subsistence economics in the period ca. 13,000-10,000 years BP. The Natufians represent a local population with strong biologic ties to the more ancient Upper Paleol…
Use of the Hand Bones Roentgenographs in the Prediction of Age in Nine Human Populations
The major aim of this study was to develop an accurate method of age prediction for a wide range of ages, based on the roentgenographic assessment of the hand bones, for use in paleoanthropology and forensic medicine. The roentgenographs of the hand bones were assessed in 5756 individuals, 2683 males and 3073 females, aged 17-93 and 17-89, respectively, belonging to 9 ethnic groups from the former USSR, Israel, and Sinai peninsula (Egypt). For ea…
Evidence on major gene control of cortical index in pedigree data from middle dalmatia, croatia
Modelling of age-related bone loss using cross-sectional data
The change of phalangeal BMD with age may be best described by a two-interval function, regardless of sex and ethnic background. However, specific parameter estimates depend both on gender and ethnic affiliation. This study has yielded a well-fitted model of BMD dependence on age suitable for further use in population studies
A genome wide linkage scan of metacarpal size and geometry in the Framingham Study
Bone geometry is a significant component of bone strength, and has a clinical utility in predicting fractures and quantifying bone loss. Bone geometry is known to have a substantial genetic component. We performed linkage analysis to identify chromosomal regions governing metacarpal bone geometry. A genome‐wide scan (with a set of 615 markers with spacing of ∼5.7 cM) was performed on 1,702 individuals from 330 extended families of the Framingham …
Medicine (7 obras) · Demography (5 obras) · Biology (4 obras) · Bone health and osteoporosis research (4 obras) · Forensic Anthropology and Bioarchaeology Studies (4 obras) · Genetic Associations and Epidemiology (4 obras) · Internal Medicine (4 obras) · Mathematics (4 obras) · Archaeology (3 obras) · Bone Metabolism and Diseases (3 obras)