Bernard Rachet
Datos Biográficos
| ID | 4864481 |
|---|---|
| NOMBRE | Bernard Rachet |
| NOMBRES | Bernard |
| APELLIDO | Rachet |
| FIRMA | RACHET B |
| AFILIACIONES | London School of Hygiene & Tropical Medicine |
| ORCID | 0000-0001-5837-7773 |
| VERIFICADO | Sí |
| TOTAL DE OBRAS | 20 |
| TOTAL DE CITAS | 31 |
| TOTAL COMO AUTOR | 20 |
| TOTAL COMO EDITOR | 0 |
| PRIMER AÑO DE PUBLICACIÓN | 2005 |
| AÑO MÁS RECIENTE DE PUBLICACIÓN | 2026 |
| ÍNDICE H | 3 |
How equity in cancer services has been defined and measured, and why it matters
Has Covid-19 Exacerbated Ethnic-Related Inequalities in Cancer Care in the UK? Findings from a Narrative Review with a Systematic Search
Ethnic inequalities in cancer care have long been a concern in the UK, with minoritised populations facing inequalities in access, diagnosis, treatment, and outcomes. The COVID-19 pandemic exacerbated these inequities, worsening barriers to care. This narrative literature review, which incorporates a systematic search, examines the impact of the pandemic on ethnic inequalities in cancer care in the UK. Findings indicate that due to the pandemic, …
Associations between treatments, comorbidities and multidimensional aspects of quality of life among patients with advanced cancer in the Netherlands—a 2017–2020 multicentre cross-sectional study
Our study identified associations between specific cancer treatments, lower QoL and more symptoms. Monitoring symptoms may improve QoL of patients with advanced cancer. Producing more evidence from real life data would help physicians in better identifying patients who require additional supportive care
Health-related quality of life in cancer immunotherapy
The CLD illustrates the valuable contribution of a systems perspective to quality-of-life research. This systems-based qualitative representation gives insight on strategies to inhibit harmful effects, enhance beneficial effects, and inherent tradeoffs within the system. The CLD identifies gaps in the literature and offers a communication tool for diverse stakeholders. Our research method provides an example for studying the complexities of quali…
Variation in colon cancer survival for patients living and receiving care in London, 2006–2013
BACKGROUND: Marked geographical disparities in survival from colon cancer have been consistently described in England. Similar patterns have been observed within London, almost mimicking a microcosm of the country's survival patterns. This evidence has suggested that the area of residence plays an important role in the survival from cancer. METHODS: We analysed the survival from colon cancer of patients diagnosed in 2006-2013, in a pre-pandemic p…
Probabilities of ICU admission and hospital discharge according to patient characteristics in the designated Covid-19 hospital of Kuwait
This study provides useful insight in describing the probabilities of ICU admission and hospital discharge according to age, gender, and comorbidities among confirmed COVID-19 cases in Kuwait. A web-tool is also provided to allow the user to estimate these probabilities for any combination of these covariates. These probabilities enable deeper understanding of the hospital demand according to patient characteristics which is essential to hospital…
Socioeconomic gaps over time in colorectal cancer survival in England
BACKGROUND: Despite persistent reports of socioeconomic inequalities in colorectal cancer survival in England, the magnitude of survival differences has not been fully evaluated. METHODS: Patients diagnosed with colon cancer (n=68 169) and rectal cancer (n=38 267) in England (diagnosed between January 2010 and March 2013) were analysed as a retrospective cohort study using the National Cancer Registry data linked with other population-based healt…
The impact of the Covid-19 pandemic on cancer deaths due to delays in diagnosis in England, UK
BACKGROUND: Since a national lockdown was introduced across the UK in March, 2020, in response to the COVID-19 pandemic, cancer screening has been suspended, routine diagnostic work deferred, and only urgent symptomatic cases prioritised for diagnostic intervention. In this study, we estimated the impact of delays in diagnosis on cancer survival outcomes in four major tumour types. METHODS: In this national population-based modelling study, we us…
Deprivation-specific life tables using multivariable flexible modelling – trends from 2000–2002 to 2010–2012, Portugal
Persistent differences in mortality and life expectancy were observed according to ecological socioeconomic deprivation. These differences were larger among men and mostly marked at birth for both sexes
Development of a cross-cultural deprivation index in five European countries
BACKGROUND: Despite a concerted policy effort in Europe, social inequalities in health are a persistent problem. Developing a standardised measure of socioeconomic level across Europe will improve the understanding of the underlying mechanisms and causes of inequalities. This will facilitate developing, implementing and assessing new and more effective policies, and will improve the comparability and reproducibility of health inequality studies a…
Multivariable flexible modelling for estimating complete, smoothed life tables for sub-national populations
The flexible Poisson model is recommended because it derives robust and unbiased estimates for sub-populations without making strong assumptions about age-specific mortality profiles. Fixing knots a priori in the final model greatly improves fit at the young ages
A novel ecological methodology for constructing ethnic-majority life tables in the absence of individual ethnicity information
BACKGROUND: Deprivation-specific life tables have been in use for some time, but health outcomes are also known to vary by ethnicity over and above deprivation. The mortality experiences of ethnic groups are little studied in the UK, however, because ethnicity is not captured on death certificates. METHODS: Population data for all Output Areas (OAs) in England and Wales were stratified by age-group, sex and ethnic proportion, and matched to the d…
Inequalities in non-small cell lung cancer treatment and mortality
BACKGROUND: Non-small cell lung cancer (NSCLC) comprises approximately 85% of all lung cancer cases, and surgery is the preferred treatment for patients. The National Health Service established Primary Care Trusts (PCTs) in 2002 to manage local health needs. We investigate whether PCTs with a lower uptake of surgical treatment are those with above-average mortality 1 year after diagnosis. The applied methods can be used to monitor the performance…
The influence of geographical access to health care and material deprivation on colorectal cancer survival
Geographical variation in cancer survival in England, 1991–2006
BACKGROUND: Reducing geographical inequalities in cancer survival in England was a key aim of the Calman-Hine Report (1995) and the NHS Cancer Plan (2000). This study assesses whether geographical inequalities changed following these policy developments by analysing the trend in 1-year relative survival in the 28 cancer networks of England. METHODS: Population-based age-standardised relative survival at 1 year is estimated for 1.4 million patient…
Socio-economic inequalities in cancer survival in England after the NHS cancer plan
Objectives Socio-economic inequalities in survival have been reported for most adult cancers in England. The NHS Cancer Plan (2000) aimed to improve cancer patient survival, and tackle inequalities in survival between people from deprived and affluent backgrounds. Recent observations suggest some improvements in survival have accelerated since implementation of the Cancer Plan. This study investigates the efficacy of the Cancer Plan in tackling i…
Regional disparities in cancer survival following the NHS National Cancer Plan for England
Objective Reducing geographic inequalities in survival from cancer in England was a key aim of the Calman-Hine Report (1995) and the NHS Cancer Plan (2000). In this paper we assess whether regional differences have diminished following these policy developments by analysing the trend in one-year relative survival from six cancers in the 28 Cancer Networks of England. Methods We estimated population-based relative survival at one year for 1.4 mill…
Would compliance with cancer care standards improve survival for breast, colorectal and lung cancers
OBJECTIVE: To investigate whether cancer service standards are associated with survival for breast, colorectal and lung cancers at population level. METHODS: Standards of hospital cancer services in England, measured in 2001, were aggregated for 30 cancer networks covering populations of between 500 000 and 3 million people, and compared with 1-year and 5-year relative cancer survival for the incident period 1996-2001, using rank correlation. RES…
Origins of socio-economic inequalities in cancer survival
Geographical variation in life expectancy at birth in England and Wales is largely explained by deprivation
Study objective: To describe the population mortality profile of England and Wales by deprivation and in each government office region (GOR) during 1998, and to quantify the influence of geography and deprivation in determining life expectancy. Design: Construction of life tables describing age specific mortality rates and life expectancy at birth from death registrations and estimated population counts. Life tables were created for (a) quintiles…
Geographical variation in life expectancy at birth in England and Wales is largely explained by deprivation
Study objective: To describe the population mortality profile of England and Wales by deprivation and in each government office region (GOR) during 1998, and to quantify the influence of geography and deprivation in determining life expectancy. Design: Construction of life tables describing age specific mortality rates and life expectancy at birth from death registrations and estimated population counts. Life tables were created for (a) quintiles…
Development of a cross-cultural deprivation index in five European countries
BACKGROUND: Despite a concerted policy effort in Europe, social inequalities in health are a persistent problem. Developing a standardised measure of socioeconomic level across Europe will improve the understanding of the underlying mechanisms and causes of inequalities. This will facilitate developing, implementing and assessing new and more effective policies, and will improve the comparability and reproducibility of health inequality studies a…
A novel ecological methodology for constructing ethnic-majority life tables in the absence of individual ethnicity information
BACKGROUND: Deprivation-specific life tables have been in use for some time, but health outcomes are also known to vary by ethnicity over and above deprivation. The mortality experiences of ethnic groups are little studied in the UK, however, because ethnicity is not captured on death certificates. METHODS: Population data for all Output Areas (OAs) in England and Wales were stratified by age-group, sex and ethnic proportion, and matched to the d…
Socioeconomic gaps over time in colorectal cancer survival in England
BACKGROUND: Despite persistent reports of socioeconomic inequalities in colorectal cancer survival in England, the magnitude of survival differences has not been fully evaluated. METHODS: Patients diagnosed with colon cancer (n=68 169) and rectal cancer (n=38 267) in England (diagnosed between January 2010 and March 2013) were analysed as a retrospective cohort study using the National Cancer Registry data linked with other population-based healt…
Inequalities in non-small cell lung cancer treatment and mortality
BACKGROUND: Non-small cell lung cancer (NSCLC) comprises approximately 85% of all lung cancer cases, and surgery is the preferred treatment for patients. The National Health Service established Primary Care Trusts (PCTs) in 2002 to manage local health needs. We investigate whether PCTs with a lower uptake of surgical treatment are those with above-average mortality 1 year after diagnosis. The applied methods can be used to monitor the performance…
The influence of geographical access to health care and material deprivation on colorectal cancer survival
Geographical variation in cancer survival in England, 1991–2006
BACKGROUND: Reducing geographical inequalities in cancer survival in England was a key aim of the Calman-Hine Report (1995) and the NHS Cancer Plan (2000). This study assesses whether geographical inequalities changed following these policy developments by analysing the trend in 1-year relative survival in the 28 cancer networks of England. METHODS: Population-based age-standardised relative survival at 1 year is estimated for 1.4 million patient…
Geographical variation in life expectancy at birth in England and Wales is largely explained by deprivation
Study objective: To describe the population mortality profile of England and Wales by deprivation and in each government office region (GOR) during 1998, and to quantify the influence of geography and deprivation in determining life expectancy. Design: Construction of life tables describing age specific mortality rates and life expectancy at birth from death registrations and estimated population counts. Life tables were created for (a) quintiles…
Origins of socio-economic inequalities in cancer survival
Would compliance with cancer care standards improve survival for breast, colorectal and lung cancers
OBJECTIVE: To investigate whether cancer service standards are associated with survival for breast, colorectal and lung cancers at population level. METHODS: Standards of hospital cancer services in England, measured in 2001, were aggregated for 30 cancer networks covering populations of between 500 000 and 3 million people, and compared with 1-year and 5-year relative cancer survival for the incident period 1996-2001, using rank correlation. RES…
Socio-economic inequalities in cancer survival in England after the NHS cancer plan
Objectives Socio-economic inequalities in survival have been reported for most adult cancers in England. The NHS Cancer Plan (2000) aimed to improve cancer patient survival, and tackle inequalities in survival between people from deprived and affluent backgrounds. Recent observations suggest some improvements in survival have accelerated since implementation of the Cancer Plan. This study investigates the efficacy of the Cancer Plan in tackling i…
Regional disparities in cancer survival following the NHS National Cancer Plan for England
Objective Reducing geographic inequalities in survival from cancer in England was a key aim of the Calman-Hine Report (1995) and the NHS Cancer Plan (2000). In this paper we assess whether regional differences have diminished following these policy developments by analysing the trend in one-year relative survival from six cancers in the 28 Cancer Networks of England. Methods We estimated population-based relative survival at one year for 1.4 mill…
Geographical variation in cancer survival in England, 1991–2006
BACKGROUND: Reducing geographical inequalities in cancer survival in England was a key aim of the Calman-Hine Report (1995) and the NHS Cancer Plan (2000). This study assesses whether geographical inequalities changed following these policy developments by analysing the trend in 1-year relative survival in the 28 cancer networks of England. METHODS: Population-based age-standardised relative survival at 1 year is estimated for 1.4 million patient…
The influence of geographical access to health care and material deprivation on colorectal cancer survival
Multivariable flexible modelling for estimating complete, smoothed life tables for sub-national populations
The flexible Poisson model is recommended because it derives robust and unbiased estimates for sub-populations without making strong assumptions about age-specific mortality profiles. Fixing knots a priori in the final model greatly improves fit at the young ages
A novel ecological methodology for constructing ethnic-majority life tables in the absence of individual ethnicity information
BACKGROUND: Deprivation-specific life tables have been in use for some time, but health outcomes are also known to vary by ethnicity over and above deprivation. The mortality experiences of ethnic groups are little studied in the UK, however, because ethnicity is not captured on death certificates. METHODS: Population data for all Output Areas (OAs) in England and Wales were stratified by age-group, sex and ethnic proportion, and matched to the d…
Inequalities in non-small cell lung cancer treatment and mortality
BACKGROUND: Non-small cell lung cancer (NSCLC) comprises approximately 85% of all lung cancer cases, and surgery is the preferred treatment for patients. The National Health Service established Primary Care Trusts (PCTs) in 2002 to manage local health needs. We investigate whether PCTs with a lower uptake of surgical treatment are those with above-average mortality 1 year after diagnosis. The applied methods can be used to monitor the performance…
Development of a cross-cultural deprivation index in five European countries
BACKGROUND: Despite a concerted policy effort in Europe, social inequalities in health are a persistent problem. Developing a standardised measure of socioeconomic level across Europe will improve the understanding of the underlying mechanisms and causes of inequalities. This will facilitate developing, implementing and assessing new and more effective policies, and will improve the comparability and reproducibility of health inequality studies a…
Deprivation-specific life tables using multivariable flexible modelling – trends from 2000–2002 to 2010–2012, Portugal
Persistent differences in mortality and life expectancy were observed according to ecological socioeconomic deprivation. These differences were larger among men and mostly marked at birth for both sexes
The impact of the Covid-19 pandemic on cancer deaths due to delays in diagnosis in England, UK
BACKGROUND: Since a national lockdown was introduced across the UK in March, 2020, in response to the COVID-19 pandemic, cancer screening has been suspended, routine diagnostic work deferred, and only urgent symptomatic cases prioritised for diagnostic intervention. In this study, we estimated the impact of delays in diagnosis on cancer survival outcomes in four major tumour types. METHODS: In this national population-based modelling study, we us…
Probabilities of ICU admission and hospital discharge according to patient characteristics in the designated Covid-19 hospital of Kuwait
This study provides useful insight in describing the probabilities of ICU admission and hospital discharge according to age, gender, and comorbidities among confirmed COVID-19 cases in Kuwait. A web-tool is also provided to allow the user to estimate these probabilities for any combination of these covariates. These probabilities enable deeper understanding of the hospital demand according to patient characteristics which is essential to hospital…
Socioeconomic gaps over time in colorectal cancer survival in England
BACKGROUND: Despite persistent reports of socioeconomic inequalities in colorectal cancer survival in England, the magnitude of survival differences has not been fully evaluated. METHODS: Patients diagnosed with colon cancer (n=68 169) and rectal cancer (n=38 267) in England (diagnosed between January 2010 and March 2013) were analysed as a retrospective cohort study using the National Cancer Registry data linked with other population-based healt…
Health-related quality of life in cancer immunotherapy
The CLD illustrates the valuable contribution of a systems perspective to quality-of-life research. This systems-based qualitative representation gives insight on strategies to inhibit harmful effects, enhance beneficial effects, and inherent tradeoffs within the system. The CLD identifies gaps in the literature and offers a communication tool for diverse stakeholders. Our research method provides an example for studying the complexities of quali…
Variation in colon cancer survival for patients living and receiving care in London, 2006–2013
BACKGROUND: Marked geographical disparities in survival from colon cancer have been consistently described in England. Similar patterns have been observed within London, almost mimicking a microcosm of the country's survival patterns. This evidence has suggested that the area of residence plays an important role in the survival from cancer. METHODS: We analysed the survival from colon cancer of patients diagnosed in 2006-2013, in a pre-pandemic p…
Associations between treatments, comorbidities and multidimensional aspects of quality of life among patients with advanced cancer in the Netherlands—a 2017–2020 multicentre cross-sectional study
Our study identified associations between specific cancer treatments, lower QoL and more symptoms. Monitoring symptoms may improve QoL of patients with advanced cancer. Producing more evidence from real life data would help physicians in better identifying patients who require additional supportive care
How equity in cancer services has been defined and measured, and why it matters
Has Covid-19 Exacerbated Ethnic-Related Inequalities in Cancer Care in the UK? Findings from a Narrative Review with a Systematic Search
Ethnic inequalities in cancer care have long been a concern in the UK, with minoritised populations facing inequalities in access, diagnosis, treatment, and outcomes. The COVID-19 pandemic exacerbated these inequities, worsening barriers to care. This narrative literature review, which incorporates a systematic search, examines the impact of the pandemic on ethnic inequalities in cancer care in the UK. Findings indicate that due to the pandemic, …
Medicine (16 obras) · Cancer (12 obras) · Demography (11 obras) · Global Cancer Incidence and Screening (11 obras) · Internal Medicine (11 obras) · Population (11 obras) · Internal Medicine (9 obras) · Environmental health (8 obras) · Cancer registry (7 obras) · Gerontology (7 obras)