Paul Zimmet
Datos Biográficos
| ID | 4975584 |
|---|---|
| NOMBRE | Paul Zimmet |
| NOMBRES | Paul |
| APELLIDO | Zimmet |
| FIRMA | ZIMMET P |
| AFILIACIONES | Baker Heart and Diabetes Institute |
| ORCID | 0000-0003-0627-0776 |
| VERIFICADO | Sí |
| TOTAL DE OBRAS | 30 |
| TOTAL DE CITAS | 11 |
| TOTAL COMO AUTOR | 30 |
| TOTAL COMO EDITOR | 0 |
| PRIMER AÑO DE PUBLICACIÓN | 1982 |
| AÑO MÁS RECIENTE DE PUBLICACIÓN | 2024 |
| ÍNDICE H | 2 |
Worldwide trends in underweight and obesity from 1990 to 2022
BACKGROUND: Underweight and obesity are associated with adverse health outcomes throughout the life course. We estimated the individual and combined prevalence of underweight or thinness and obesity, and their changes, from 1990 to 2022 for adults and school-aged children and adolescents in 200 countries and territories. METHODS: ). For school-aged children and adolescents, we report thinness (BMI 2 SD above the median). FINDINGS: From 1990 to 20…
Prevalence and risk factors of hypertension in Mauritius
Hypertension, a highly prevalent non-communicable disease is a leading cause of death and disability worldwide. In the Republic of Mauritius, the growing number of elderly people along with a rise in overweight and obese populations indicate a looming increase in hypertension prevalence. Given its profound burden on the population and economy, updated insights into the burden and determinants of hypertension in Mauritius is crucial for developing…
Prevalence and social determinants of smoking among men in Mauritius
BACKGROUND: Mauritius has implemented a range of stringent policies to control smoking and promote public health. Regular monitoring focuses on the prevalence of tobacco use, yet there is a gap in understanding its socio-economic patterns. OBJECTIVE: The aim of this study was to estimate the prevalence of tobacco smoking and to identify the social determinants associated with smoking among men in Mauritius in 2021. METHODS: This is a cross-sectio…
Direct assessment of mental health and metabolic syndrome amongst Indonesian adolescents
Non-communicable diseases (NCDs) are the leading cause of morbidity and mortality globally, with the burden largely borne by people living in low- and middle-income countries. Adolescents are central to NCD control through the potential to modify risks and alter the trajectory of these diseases across the life-course. However, an absence of epidemiological data has contributed to the relative exclusion of adolescents from policies and responses. …
Predictors of Hypertension in Mauritians with Normotension and Prehypertension at Baseline
Information on the predictors of future hypertension in Mauritians with prehypertension is scant. The aim of this study was to analyze the 5-year and 11-year risk of hypertension and its predictors in people with normotension and prehypertension at baseline in Mauritius in 1987. This was a retrospective cohort study of 883 men and 1194 women of Mauritian Indian and Mauritian Creole ethnicity, aged 25−74 years old, free of hypertension at baseline…
Continued increases in blood pressure over two decades in Samoa (1991–2013); around one-third of the increase explained by rising obesity levels
Significant increases have occurred in SBP/DBP and hypertension prevalence in both sexes in Samoa during 1991-2013, which would contribute significantly to premature mortality from cardiovascular disease. Obesity accounts for around one-third of the rising trend in blood pressure in the Samoan population. Strengthening of population control of hypertension through reduction in obesity and salt intake, and case detection and treatment through prim…
Tobacco smoking trends in Samoa over four decades
BACKGROUND: The island country of Samoa (population 188,000 in 2011) forms part of Polynesia in the South Pacific. Over the past several decades Samoa has experienced exceptional modernization and globalization of many sectors of society, with noncommunicable diseases (NCD) now the leading cause of morbidity and mortality. The evolution of risk factor prevalence underpinning the increase in NCDs, however, has not been well described, including to…
Cluster randomised controlled trial of a peer-led lifestyle intervention program
Australia and New Zealand Clinical Trials Registry: ACTRN12611000262909
Breaking Up Prolonged Sitting Reduces Postprandial Glucose and Insulin Responses
OBJECTIVE: Observational studies show breaking up prolonged sitting has beneficial associations with cardiometabolic risk markers, but intervention studies are required to investigate causality. We examined the acute effects on postprandial glucose and insulin levels of uninterrupted sitting compared with sitting interrupted by brief bouts of light- or moderate-intensity walking. RESEARCH DESIGN AND METHODS: Overweight/obese adults (n = 19), aged…
High rates of albuminuria but not of low eGFR in Urban Indigenous Australians
Given the significant excess of ESKD observed in Indigenous versus non-Indigenous Australians, these findings could suggest either: albuminuria may be a better prognostic marker of kidney disease than low eGFR; that eGFR equations may be inaccurate in the Indigenous population; a less marked differential between Indigenous and non-Indigenous Australians for ESKD rates in urban compared to remote regions; or that differences in the pathophysiology…
Global estimates of the prevalence of diabetes for 2010 and 2030
Television Viewing Time and Mortality
Background— Television viewing time, the predominant leisure-time sedentary behavior, is associated with biomarkers of cardiometabolic risk, but its relationship with mortality has not been studied. We examined the associations of prolonged television viewing time with all-cause, cardiovascular disease (CVD), cancer, and non-CVD/noncancer mortality in Australian adults. Methods and Results— Television viewing time in relation to subsequent all-ca…
Harmonizing the Metabolic Syndrome
A cluster of risk factors for cardiovascular disease and type 2 diabetes mellitus, which occur together more often than by chance alone, have become known as the metabolic syndrome. The risk factors include raised blood pressure, dyslipidemia (raised triglycerides and lowered high-density lipoprotein cholesterol), raised fasting glucose, and central obesity. Various diagnostic criteria have been proposed by different organizations over the past d…
Breaks in Sedentary Time
OBJECTIVE—Total sedentary (absence of whole-body movement) time is associated with obesity, abnormal glucose metabolism, and the metabolic syndrome. In addition to the effects of total sedentary time, the manner in which it is accumulated may also be important. We examined the association of breaks in objectively measured sedentary time with biological markers of metabolic risk. RESEARCH DESIGN AND METHODS—Participants (n = 168, mean age 53.4 yea…
Objectively Measured Sedentary Time, Physical Activity, and Metabolic Risk
OBJECTIVE—We examined the associations of objectively measured sedentary time and physical activity with continuous indexes of metabolic risk in Australian adults without known diabetes. RESEARCH DESIGN AND METHODS—An accelerometer was used to derive the percentage of monitoring time spent sedentary and in light-intensity and moderate-to-vigorous–intensity activity, as well as mean activity intensity, in 169 Australian Diabetes, Obesity and Lifes…
The metabolic syndrome in children and adolescents ? an IDF consensus report
The growing worldwide prevalence of type 2 diabetes mellitus in the young, as underlined by an earlier International Diabetes Federation (IDF) Consensus Statement 1, has highlighted a significant shortfall of data on the epidemiology of the disorder and the identification and treatment of children and adolescents at risk of progression to this disease. Urbanization, unhealthy diets, and increasingly sedentary lifestyles have contributed to increa…
Socioeconomic status and diabetes among urban Indigenous Australians aged 15–64 years in the DRUID study
The relationship between SES and diabetes among Indigenous Australians in this study is consistent with the patterns observed in developed countries, rather than those in some developing countries
Metabolic syndrome—a new world‐wide definition. A Consensus Statement from the International Diabetes Federation
Aims To establish a unified working diagnostic tool for the metabolic syndrome (MetS) that is convenient to use in clinical practice and that can be used world‐wide so that data from different countries can be compared. An additional aim was to highlight areas where more research into the MetS is needed. Participants The International Diabetes Federation (IDF) convened a workshop held 12–14 May 2004 in London, UK. The 21 participants included exp…
Study Protocol – Diabetes and related conditions in urban Indigenous people in the Darwin, Australia region
Despite lower than anticipated recruitment, this is, to our knowledge, the largest study ever conducted on the health of Indigenous Australians living in urban areas, a group which comprises the majority of Australia's Indigenous population but about whose health and wellbeing relatively little is known. The study is well-placed to provide new information that can be used by policy makers and service providers to improve the delivery of services …
Association of Genetic Variation Within UBL5 with Phenotypes of Metabolic Syndrome
The BEACON gene was initially identified using the differential display polymerase chain reaction on hypothalamic mRNA samples collected from lean and obese Psammomys obesus, a polygenic animal model of obesity. Hypothalamic BEACON gene expression was positively correlated with percentage of body fat, and intracerebroventricular infusion of the Beacon protein resulted in a dose-dependent increase in food intake and body weight. The human homolog …
The metabolic syndrome
The metabolic syndrome—a new worldwide definition
Dietary Westernisation
Objectives The aims of the study were to provide information that will contribute to conceptualising what is called ‘dietary Westernisation’, and to provide an example of measuring it on an individual level. Design Food consumption frequency and demographic data on adults in Mauritius were examined in 1988, 1992 and 1998. In 1992, a 24-hour recall was also included. The cross-sectional samples consisted of 1115 (age 25–74 years) Mauritians in 198…
Diet, nutrition and the prevention of type 2 diabetes
Objectives: The overall objective of this study was to evaluate and provide evidence and recommendations on current published literature about diet and lifestyle in the prevention of type 2 diabetes. Design: Epidemiological and experimental studies, focusing on nutritional intervention in the prevention of type 2 diabetes are used to make disease-specific recommendations. Long-term cohort studies are given the most weight as to strength of eviden…
Global and societal implications of the diabetes epidemic
Socioeconomic status and diabetes among urban Indigenous Australians aged 15–64 years in the DRUID study
The relationship between SES and diabetes among Indigenous Australians in this study is consistent with the patterns observed in developed countries, rather than those in some developing countries
Changing mortality patterns in Nauruans
An analysis of mortality data for the years 1982-5 was carried out for the Micronesian population (aged 15 years and over) of the central Pacific Island, Nauru. Among males, the most common causes of death were circulatory system disorders (33.3%), accidents (25.2%), and diabetes mellitus (12.1%). The majority of accidents occurred in the 15-34 year age group and involved motor vehicles. Among females, neoplasms (almost all lung and cervix) (22.4…
Blood pressure in Papua New Guinea
The results of a population survey of blood pressure in the adult residents of two highland villages in the Asaro Valley, Papua New Guinea are reported. The survey was conducted in 1983 as part of a wider epidemiological investigation of non-communicable disease in Papua New Guinea. Response to the survey was 95%, and 308 subjects were examined. Population estimates of both systolic and diastolic blood pressures were low and there was a virtual a…
HLA antigens in four Pacific populations with non-insulin-dependent diabetes mellitus
HLA antigen distributions in persons with normal and abnormal glucose tolerance were compared in four Pacific populations. The populations included Melanesians from the Fijian Islands, Loyalty Islands and mainland New Caledonia and Polynesians from the Wallis Islands. HLA-DR results are provided for the first time for Pacific groups. In Polynesians, HLA-B22 was increased in frequency in patients with non-insulin-dependent diabetes mellitus and al…
Blood pressure in Papua New Guinea
The results of a population survey of blood pressure in the adult residents of two highland villages in the Asaro Valley, Papua New Guinea are reported. The survey was conducted in 1983 as part of a wider epidemiological investigation of non-communicable disease in Papua New Guinea. Response to the survey was 95%, and 308 subjects were examined. Population estimates of both systolic and diastolic blood pressures were low and there was a virtual a…
Changing mortality patterns in Nauruans
An analysis of mortality data for the years 1982-5 was carried out for the Micronesian population (aged 15 years and over) of the central Pacific Island, Nauru. Among males, the most common causes of death were circulatory system disorders (33.3%), accidents (25.2%), and diabetes mellitus (12.1%). The majority of accidents occurred in the 15-34 year age group and involved motor vehicles. Among females, neoplasms (almost all lung and cervix) (22.4…
Diet in an urban Papua New Guinea population with high levels of cardiovascular risk factors
Usual food consumption patterns and nutrient intakes were estimated by food frequency questionnaire in the urban Wanigela people of Koki in Port Moresby, Papua New Guinea (PNG). This group is characterised by a high prevalence of non‐insulin‐dependent diabetes mellitus (NIDDM) and risk factors for cardiovascular disease (CVD). Dietary data were available for 285 subjects, 38% of subjects attending a larger health survey: the study group was consi…
Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1
The classification of diabetes mellitus and the tests used for its diagnosis were brought into order by the National Diabetes Data Group of the USA and the second World Health Organization Expert Committee on Diabetes Mellitus in 1979 and 1980. Apart from minor modifications by WHO in 1985, little has been changed since that time. There is however considerable new knowledge regarding the aetiology of different forms of diabetes as well as more in…
Global and societal implications of the diabetes epidemic
Diet, nutrition and the prevention of type 2 diabetes
Objectives: The overall objective of this study was to evaluate and provide evidence and recommendations on current published literature about diet and lifestyle in the prevention of type 2 diabetes. Design: Epidemiological and experimental studies, focusing on nutritional intervention in the prevention of type 2 diabetes are used to make disease-specific recommendations. Long-term cohort studies are given the most weight as to strength of eviden…
The metabolic syndrome
The metabolic syndrome—a new worldwide definition
Dietary Westernisation
Objectives The aims of the study were to provide information that will contribute to conceptualising what is called ‘dietary Westernisation’, and to provide an example of measuring it on an individual level. Design Food consumption frequency and demographic data on adults in Mauritius were examined in 1988, 1992 and 1998. In 1992, a 24-hour recall was also included. The cross-sectional samples consisted of 1115 (age 25–74 years) Mauritians in 198…
Metabolic syndrome—a new world‐wide definition. A Consensus Statement from the International Diabetes Federation
Aims To establish a unified working diagnostic tool for the metabolic syndrome (MetS) that is convenient to use in clinical practice and that can be used world‐wide so that data from different countries can be compared. An additional aim was to highlight areas where more research into the MetS is needed. Participants The International Diabetes Federation (IDF) convened a workshop held 12–14 May 2004 in London, UK. The 21 participants included exp…
Study Protocol – Diabetes and related conditions in urban Indigenous people in the Darwin, Australia region
Despite lower than anticipated recruitment, this is, to our knowledge, the largest study ever conducted on the health of Indigenous Australians living in urban areas, a group which comprises the majority of Australia's Indigenous population but about whose health and wellbeing relatively little is known. The study is well-placed to provide new information that can be used by policy makers and service providers to improve the delivery of services …
Association of Genetic Variation Within UBL5 with Phenotypes of Metabolic Syndrome
The BEACON gene was initially identified using the differential display polymerase chain reaction on hypothalamic mRNA samples collected from lean and obese Psammomys obesus, a polygenic animal model of obesity. Hypothalamic BEACON gene expression was positively correlated with percentage of body fat, and intracerebroventricular infusion of the Beacon protein resulted in a dose-dependent increase in food intake and body weight. The human homolog …
The metabolic syndrome in children and adolescents ? an IDF consensus report
The growing worldwide prevalence of type 2 diabetes mellitus in the young, as underlined by an earlier International Diabetes Federation (IDF) Consensus Statement 1, has highlighted a significant shortfall of data on the epidemiology of the disorder and the identification and treatment of children and adolescents at risk of progression to this disease. Urbanization, unhealthy diets, and increasingly sedentary lifestyles have contributed to increa…
Socioeconomic status and diabetes among urban Indigenous Australians aged 15–64 years in the DRUID study
The relationship between SES and diabetes among Indigenous Australians in this study is consistent with the patterns observed in developed countries, rather than those in some developing countries
Breaks in Sedentary Time
OBJECTIVE—Total sedentary (absence of whole-body movement) time is associated with obesity, abnormal glucose metabolism, and the metabolic syndrome. In addition to the effects of total sedentary time, the manner in which it is accumulated may also be important. We examined the association of breaks in objectively measured sedentary time with biological markers of metabolic risk. RESEARCH DESIGN AND METHODS—Participants (n = 168, mean age 53.4 yea…
Objectively Measured Sedentary Time, Physical Activity, and Metabolic Risk
OBJECTIVE—We examined the associations of objectively measured sedentary time and physical activity with continuous indexes of metabolic risk in Australian adults without known diabetes. RESEARCH DESIGN AND METHODS—An accelerometer was used to derive the percentage of monitoring time spent sedentary and in light-intensity and moderate-to-vigorous–intensity activity, as well as mean activity intensity, in 169 Australian Diabetes, Obesity and Lifes…
Harmonizing the Metabolic Syndrome
A cluster of risk factors for cardiovascular disease and type 2 diabetes mellitus, which occur together more often than by chance alone, have become known as the metabolic syndrome. The risk factors include raised blood pressure, dyslipidemia (raised triglycerides and lowered high-density lipoprotein cholesterol), raised fasting glucose, and central obesity. Various diagnostic criteria have been proposed by different organizations over the past d…
Global estimates of the prevalence of diabetes for 2010 and 2030
Television Viewing Time and Mortality
Background— Television viewing time, the predominant leisure-time sedentary behavior, is associated with biomarkers of cardiometabolic risk, but its relationship with mortality has not been studied. We examined the associations of prolonged television viewing time with all-cause, cardiovascular disease (CVD), cancer, and non-CVD/noncancer mortality in Australian adults. Methods and Results— Television viewing time in relation to subsequent all-ca…
High rates of albuminuria but not of low eGFR in Urban Indigenous Australians
Given the significant excess of ESKD observed in Indigenous versus non-Indigenous Australians, these findings could suggest either: albuminuria may be a better prognostic marker of kidney disease than low eGFR; that eGFR equations may be inaccurate in the Indigenous population; a less marked differential between Indigenous and non-Indigenous Australians for ESKD rates in urban compared to remote regions; or that differences in the pathophysiology…
Breaking Up Prolonged Sitting Reduces Postprandial Glucose and Insulin Responses
OBJECTIVE: Observational studies show breaking up prolonged sitting has beneficial associations with cardiometabolic risk markers, but intervention studies are required to investigate causality. We examined the acute effects on postprandial glucose and insulin levels of uninterrupted sitting compared with sitting interrupted by brief bouts of light- or moderate-intensity walking. RESEARCH DESIGN AND METHODS: Overweight/obese adults (n = 19), aged…
Cluster randomised controlled trial of a peer-led lifestyle intervention program
Australia and New Zealand Clinical Trials Registry: ACTRN12611000262909
Tobacco smoking trends in Samoa over four decades
BACKGROUND: The island country of Samoa (population 188,000 in 2011) forms part of Polynesia in the South Pacific. Over the past several decades Samoa has experienced exceptional modernization and globalization of many sectors of society, with noncommunicable diseases (NCD) now the leading cause of morbidity and mortality. The evolution of risk factor prevalence underpinning the increase in NCDs, however, has not been well described, including to…
Predictors of Hypertension in Mauritians with Normotension and Prehypertension at Baseline
Information on the predictors of future hypertension in Mauritians with prehypertension is scant. The aim of this study was to analyze the 5-year and 11-year risk of hypertension and its predictors in people with normotension and prehypertension at baseline in Mauritius in 1987. This was a retrospective cohort study of 883 men and 1194 women of Mauritian Indian and Mauritian Creole ethnicity, aged 25−74 years old, free of hypertension at baseline…
Medicine (28 obras) · Diabetes mellitus (18 obras) · Environmental health (16 obras) · Obesity (15 obras) · Demography (13 obras) · Diabetes, Cardiovascular Risks, and Lipoproteins (13 obras) · Population (13 obras) · Endocrinology (10 obras) · Gerontology (9 obras) · Internal Medicine (9 obras)