Sudha Seshadri

• Multivariate genetic analysis of personality and cognitive traits reveals abundant pleiotropy

  Open Access•Guy Hindley, Alexey A Shadrin et al.•ARTICLE•Nature Human Behaviour•2023•Referencias: 75

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  Personality and cognitive function are heritable mental traits whose genetic foundations may be distributed across interconnected brain functions. Previous studies have typically treated these complex mental traits as distinct constructs. We applied the 'pleiotropy-informed' multivariate omnibus statistical test to genome-wide association studies of 35 measures of neuroticism and cognitive function from the UK Biobank (n = 336,993). We identified…

• Are Trends in Dementia Incidence Associated With Compression in Morbidity? Evidence From The Framingham Heart Study

  Open Access•Carole Dufouil, Alexa S Beiser et al.•ARTICLE•The Journals of Gerontology…•2018•Citada por: 2

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  In the FHS, in the last 30 years, disease duration in persons with dementia has decreased. However, age-adjusted mortality risk has slightly decreased after 1977-1983. Consequences of such trends on dementia prevalence should be investigated

• Are Trends in Dementia Incidence Associated With Compression in Morbidity? Evidence From The Framingham Heart Study

  Open Access•Carole Dufouil, Alexa S Beiser et al.•ARTICLE•The Journals of Gerontology…•2018•Citada por: 2

  Añadir item

  In the FHS, in the last 30 years, disease duration in persons with dementia has decreased. However, age-adjusted mortality risk has slightly decreased after 1977-1983. Consequences of such trends on dementia prevalence should be investigated

• Are Trends in Dementia Incidence Associated With Compression in Morbidity? Evidence From The Framingham Heart Study

  Open Access•Carole Dufouil, Alexa S Beiser et al.•ARTICLE•The Journals of Gerontology…•2018•Citada por: 2

  Añadir item

  In the FHS, in the last 30 years, disease duration in persons with dementia has decreased. However, age-adjusted mortality risk has slightly decreased after 1977-1983. Consequences of such trends on dementia prevalence should be investigated

• Multivariate genetic analysis of personality and cognitive traits reveals abundant pleiotropy

  Open Access•Guy Hindley, Alexey A Shadrin et al.•ARTICLE•Nature Human Behaviour•2023•Referencias: 75

  Añadir item

  Personality and cognitive function are heritable mental traits whose genetic foundations may be distributed across interconnected brain functions. Previous studies have typically treated these complex mental traits as distinct constructs. We applied the 'pleiotropy-informed' multivariate omnibus statistical test to genome-wide association studies of 35 measures of neuroticism and cognitive function from the UK Biobank (n = 336,993). We identified…

Big Five personality traits (1 obra) · Bioinformatics and Genomic Networks (1 obra) · Biology (1 obra) · Cardiology (1 obra) · Cognition (1 obra) · Dementia (1 obra) · Disease (1 obra) · Framingham Heart Study (1 obra) · Framingham Risk Score (1 obra) · Gene (1 obra)