Corinna N Ross
Datos Biográficos
| ID | 5204933 |
|---|---|
| NOMBRE | Corinna N Ross |
| NOMBRES | Corinna N |
| APELLIDO | Ross |
| FIRMA | ROSS C N |
| AFILIACIONES | The University of Texas at San Antonio Health Science Center |
| ORCID | 0000-0003-0299-2069 |
| VERIFICADO | Sí |
| TOTAL DE OBRAS | 21 |
| TOTAL DE CITAS | 10 |
| TOTAL COMO AUTOR | 21 |
| TOTAL COMO EDITOR | 0 |
| PRIMER AÑO DE PUBLICACIÓN | 2003 |
| AÑO MÁS RECIENTE DE PUBLICACIÓN | 2025 |
| ÍNDICE H | 1 |
Validation of Body Condition Scoring as a Screening Test for Low Body Condition and Obesity in Common Marmosets ( Callithrix jacchus )
Assessing body weight is common practice for monitoring health in common marmosets ( Callithrix jacchus ). Body composition analysis via quantitative magnetic resonance (QMR) is a more in‐depth assessment allowing measurements of lean and fat mass, but it is expensive and remains unavailable to most. Alternatively, body condition scoring (BCS) is an instrument‐free method for visually inspecting and palpating lean and fat tissue. Animals are rate…
Age‐related changes in hematological biomarkers in common marmosets
Researchers and veterinarians often use hematology and clinical chemistry to evaluate animal health. These biomarkers are relatively easy to obtain, and understanding how they change across healthy aging is critical to clinical care and diagnostics for these animals. We aimed to evaluate how clinical biomarkers from a chemistry profile and complete blood count (CBC) change with age in common marmosets ( Callithrix jacchus ). We assessed blood sam…
Genetic characterization of a captive marmoset ( Callithrix jacchus ) colony using genotype‐by‐sequencing
The marmoset is a fundamental nonhuman primate model for the study of aging, neurobiology, and many other topics. Genetic management of captive marmoset colonies is complicated by frequent chimerism in the blood and other tissues, a lack of tools to enable cost‐effective, genome‐wide interrogation of variation, and historic mergers and migrations of animals between colonies. We implemented genotype‐by‐sequencing (GBS) of hair follicle derived DNA…
Maternal weight affects placental DNA methylation of genes involved in metabolic pathways in the common marmoset monkey ( Callithrix jacchus )
Accumulating evidence suggests that dysregulation of placental DNA methylation (DNAm) is a mechanism linking maternal weight during pregnancy to metabolic programming outcomes. The common marmoset, Callithrix jaccus , is a platyrrhine primate species that has provided much insight into studies of the primate placenta, maternal condition, and metabolic programming, yet the relationships between maternal weight and placental DNAm are unknown. Here,…
Feasibility of fecal microbiota transplantation via oral gavage to safely alter gut microbiome composition in marmosets
Disruption of microbial communities within human hosts has been associated with infection, obesity, cognitive decline, cancer risk and frailty, suggesting that microbiome‐targeted therapies may be an option for improving healthspan and lifespan. The objectives of this study were to determine the feasibility of delivering fecal microbiota transplants (FMTs) to marmosets via oral gavage and to evaluate if alteration of the gut microbiome post‐FMT c…
Long‐term treatment with the mTOR inhibitor rapamycin has minor effect on clinical laboratory markers in middle‐aged marmosets
Interventions to extend lifespan and improve health with increasing age would have significant impact on a growing aged population. There are now several pharmaceutical interventions that extend lifespan in laboratory rodent models with rapamycin, an inhibitor of mechanistic target of rapamycin (mTOR) being the most well studied. In this study, we report on the hematological effects in a cohort of middle-aged common marmosets (Callithrix jacchus)…
Comparative genomics of Bifidobacterium species isolated from marmosets and humans
The genus Bifidobacterium is purported to have beneficial consequences for human health and is a major component of many gastrointestinal probiotics. Although species of Bifidobacterium are generally at low relative frequency in the adult human gastrointestinal tract, they can constitute high proportions of the gastrointestinal communities of adult marmosets. To identify genes that might be important for the maintenance of Bifidobacterium in adul…
Noninvasive cardiac psychophysiology as a tool for translational science with marmosets
The importance of marmosets for comparative and translational science has grown in recent years because of their relatively rapid development, birth cohorts of twins, family social structure, and genetic tractability. Despite this, they remain understudied in investigations of affective processes. In this methodological note, we establish the validity of using noninvasive commercially available equipment to record cardiac physiology and compute i…
The metabolome as a biomarker of mortality risk in the common marmoset
Recently, the common marmoset has been proposed as a non-human primate model of aging. Their short lifespan coupled with pathologies that are similar to humans make them an ideal model to understand the genetic, metabolic, and environmental factors that influence aging and longevity. However, many of the underlying physiological changes that occur with age in the marmoset are unknown. Here, we attempt to determine if individual metabolites are pr…
Age‐related changes in myelin of axons of the corpus callosum and cognitive decline in common marmosets
Executive control is a higher-level cognitive function that involves a range of different processes that are involved in the planning, coordination, execution, and inhibition of responses. Many of the processes associated with executive control, such as response inhibition and mental flexibility, decline with age. Degeneration of white matter architecture is considered to be the one of the key factors underlying cognitive decline associated with …
Cross‐sectional comparison of health‐span phenotypes in young versus geriatric marmosets
The development of the marmoset as a translational model for healthspan and lifespan studies relies on the characterization of health parameters in young and geriatric marmosets. This cross‐sectional study examined health phenotypes in marmosets for five domains of interest for human health and aging: mobility, cognition, metabolism, homeostasis, and immune function. Geriatric marmosets were found to have significant executive function impairment…
Age‐related changes in the marmoset gut microbiome
The gut microbiome is known to play a significant role in human health but its role in aging remains unclear. The objective of this study was to compare the gut microbiome composition between young adult and geriatric non‐human primates (marmosets) as a model of human health and disease. Stool samples were collected from geriatric (8+ years) and young adult males (2–5 years). Stool 16S ribosomal RNA V4 sequences were amplified and sequenced on th…
Body mass growth in common marmosets
While much is known about adult obesity in nonhuman primates, very little is known regarding development of childhood adiposity. As small monkeys that are easy to handle and have a relatively fast life history, common marmoset monkeys ( Callithrix jacchus ) offer interesting opportunities to examine the question of fat versus lean mass growth in a nonhuman primate. This article provides an overview of our understanding of early life growth in mas…
The Development of Obesity Begins at an Early Age in Captive Common Marmosets ( C allithrix jacchus )
Animal models to study the causes and consequences of obesity during infancy in humans would be valuable. In this study, we examine the patterns of fat mass gain from birth to 12 months in common marmosets ( C allithrix jacchus ). Lean and fat mass was measured by quantitative magnetic resonance at 1, 2, 6, and 12 months for 31 marmosets, 15 considered Normal and 16 considered Fat (>14% body fat) at 12 months. Animals were fed either the regular …
Establishing Meal Patterns by Lickometry in the Marmoset Monkey ( C allithrix jacchus)
The ability to measure and interpret variables associated with feeding behavior and food intake is essential to a variety of nonhuman primate study modalities. The development of a technique to accurately and efficiently measure food intake and meal patterning in captivity will enhance both the interpretation of foraging behavior in the wild as well as our ability to model clinically relevant human feeding pathologies. In this study, we successfu…
Female marmosets' behavioral and hormonal responses to unfamiliar intruders
The endocrine control mechanisms for female mammalian aggression have been largely unstudied. Although it has been proposed that androgens may modulate female aggressive behavior in a similar manner to males, very little conclusive evidence exists. Previous work in male marmosets found that post‐encounter increases in testosterone (T) were dependent on the intensity of aggression displayed during the aggressive encounter. We exposed female marmos…
Integration of proximate and evolutionary explanation of reproductive strategy
We offer examples of how proximate and evolutionary forms of argument may inform each other in better understanding reproductive strategy in callitrichid primates, the smallest of the anthropoid primates. In addition, we illustrate how comparative approaches, when applied judiciously, can aid in the formulation of hypotheses regarding even seemingly unique traits within a taxonomic group. In the first example, examination of the nature of genetic…
Polymorphic microsatellite loci for the common marmoset ( Callithrix jacchus ) designed using a cost‐ and time‐efficient method
We describe a cost‐ and time‐efficient method for designing new microsatellite markers in any species with substantial genomic DNA sequence data available. Using this technique, we report 14 new polymorphic dinucleotide microsatellite loci isolated from the common marmoset. The relative yield of new polymorphisms was higher with less labor than described in previous marmoset studies. Of 20 loci initially evaluated, 14 were polymorphic and amplifi…
Demographic review of a captive colony of callitrichids ( Callithrix kuhlii )
Although reports on colony demographics for a variety of callitrichid species are available in the literature, to date there has not been a detailed examination of Wied's black tufted‐ear marmoset ( Callithrix kuhlii ). The purpose of this study is to present colony demographics for C. kuhlii from the University of Nebraska at Omaha's Callitrichid Research Center from 1991 to 2002. C. kuhlii are currently held in a number of zoological parks in t…
Opportunistic mothers
Nighttime Wakefulness Associated with Infant Rearing in Callithrix kuhlii
Opportunistic mothers
Body mass growth in common marmosets
While much is known about adult obesity in nonhuman primates, very little is known regarding development of childhood adiposity. As small monkeys that are easy to handle and have a relatively fast life history, common marmoset monkeys ( Callithrix jacchus ) offer interesting opportunities to examine the question of fat versus lean mass growth in a nonhuman primate. This article provides an overview of our understanding of early life growth in mas…
Nighttime Wakefulness Associated with Infant Rearing in Callithrix kuhlii
Nighttime Wakefulness Associated with Infant Rearing in Callithrix kuhlii
Opportunistic mothers
Demographic review of a captive colony of callitrichids ( Callithrix kuhlii )
Although reports on colony demographics for a variety of callitrichid species are available in the literature, to date there has not been a detailed examination of Wied's black tufted‐ear marmoset ( Callithrix kuhlii ). The purpose of this study is to present colony demographics for C. kuhlii from the University of Nebraska at Omaha's Callitrichid Research Center from 1991 to 2002. C. kuhlii are currently held in a number of zoological parks in t…
Polymorphic microsatellite loci for the common marmoset ( Callithrix jacchus ) designed using a cost‐ and time‐efficient method
We describe a cost‐ and time‐efficient method for designing new microsatellite markers in any species with substantial genomic DNA sequence data available. Using this technique, we report 14 new polymorphic dinucleotide microsatellite loci isolated from the common marmoset. The relative yield of new polymorphisms was higher with less labor than described in previous marmoset studies. Of 20 loci initially evaluated, 14 were polymorphic and amplifi…
Integration of proximate and evolutionary explanation of reproductive strategy
We offer examples of how proximate and evolutionary forms of argument may inform each other in better understanding reproductive strategy in callitrichid primates, the smallest of the anthropoid primates. In addition, we illustrate how comparative approaches, when applied judiciously, can aid in the formulation of hypotheses regarding even seemingly unique traits within a taxonomic group. In the first example, examination of the nature of genetic…
Female marmosets' behavioral and hormonal responses to unfamiliar intruders
The endocrine control mechanisms for female mammalian aggression have been largely unstudied. Although it has been proposed that androgens may modulate female aggressive behavior in a similar manner to males, very little conclusive evidence exists. Previous work in male marmosets found that post‐encounter increases in testosterone (T) were dependent on the intensity of aggression displayed during the aggressive encounter. We exposed female marmos…
The Development of Obesity Begins at an Early Age in Captive Common Marmosets ( C allithrix jacchus )
Animal models to study the causes and consequences of obesity during infancy in humans would be valuable. In this study, we examine the patterns of fat mass gain from birth to 12 months in common marmosets ( C allithrix jacchus ). Lean and fat mass was measured by quantitative magnetic resonance at 1, 2, 6, and 12 months for 31 marmosets, 15 considered Normal and 16 considered Fat (>14% body fat) at 12 months. Animals were fed either the regular …
Establishing Meal Patterns by Lickometry in the Marmoset Monkey ( C allithrix jacchus)
The ability to measure and interpret variables associated with feeding behavior and food intake is essential to a variety of nonhuman primate study modalities. The development of a technique to accurately and efficiently measure food intake and meal patterning in captivity will enhance both the interpretation of foraging behavior in the wild as well as our ability to model clinically relevant human feeding pathologies. In this study, we successfu…
Body mass growth in common marmosets
While much is known about adult obesity in nonhuman primates, very little is known regarding development of childhood adiposity. As small monkeys that are easy to handle and have a relatively fast life history, common marmoset monkeys ( Callithrix jacchus ) offer interesting opportunities to examine the question of fat versus lean mass growth in a nonhuman primate. This article provides an overview of our understanding of early life growth in mas…
Long‐term treatment with the mTOR inhibitor rapamycin has minor effect on clinical laboratory markers in middle‐aged marmosets
Interventions to extend lifespan and improve health with increasing age would have significant impact on a growing aged population. There are now several pharmaceutical interventions that extend lifespan in laboratory rodent models with rapamycin, an inhibitor of mechanistic target of rapamycin (mTOR) being the most well studied. In this study, we report on the hematological effects in a cohort of middle-aged common marmosets (Callithrix jacchus)…
Comparative genomics of Bifidobacterium species isolated from marmosets and humans
The genus Bifidobacterium is purported to have beneficial consequences for human health and is a major component of many gastrointestinal probiotics. Although species of Bifidobacterium are generally at low relative frequency in the adult human gastrointestinal tract, they can constitute high proportions of the gastrointestinal communities of adult marmosets. To identify genes that might be important for the maintenance of Bifidobacterium in adul…
Noninvasive cardiac psychophysiology as a tool for translational science with marmosets
The importance of marmosets for comparative and translational science has grown in recent years because of their relatively rapid development, birth cohorts of twins, family social structure, and genetic tractability. Despite this, they remain understudied in investigations of affective processes. In this methodological note, we establish the validity of using noninvasive commercially available equipment to record cardiac physiology and compute i…
The metabolome as a biomarker of mortality risk in the common marmoset
Recently, the common marmoset has been proposed as a non-human primate model of aging. Their short lifespan coupled with pathologies that are similar to humans make them an ideal model to understand the genetic, metabolic, and environmental factors that influence aging and longevity. However, many of the underlying physiological changes that occur with age in the marmoset are unknown. Here, we attempt to determine if individual metabolites are pr…
Age‐related changes in myelin of axons of the corpus callosum and cognitive decline in common marmosets
Executive control is a higher-level cognitive function that involves a range of different processes that are involved in the planning, coordination, execution, and inhibition of responses. Many of the processes associated with executive control, such as response inhibition and mental flexibility, decline with age. Degeneration of white matter architecture is considered to be the one of the key factors underlying cognitive decline associated with …
Cross‐sectional comparison of health‐span phenotypes in young versus geriatric marmosets
The development of the marmoset as a translational model for healthspan and lifespan studies relies on the characterization of health parameters in young and geriatric marmosets. This cross‐sectional study examined health phenotypes in marmosets for five domains of interest for human health and aging: mobility, cognition, metabolism, homeostasis, and immune function. Geriatric marmosets were found to have significant executive function impairment…
Age‐related changes in the marmoset gut microbiome
The gut microbiome is known to play a significant role in human health but its role in aging remains unclear. The objective of this study was to compare the gut microbiome composition between young adult and geriatric non‐human primates (marmosets) as a model of human health and disease. Stool samples were collected from geriatric (8+ years) and young adult males (2–5 years). Stool 16S ribosomal RNA V4 sequences were amplified and sequenced on th…
Maternal weight affects placental DNA methylation of genes involved in metabolic pathways in the common marmoset monkey ( Callithrix jacchus )
Accumulating evidence suggests that dysregulation of placental DNA methylation (DNAm) is a mechanism linking maternal weight during pregnancy to metabolic programming outcomes. The common marmoset, Callithrix jaccus , is a platyrrhine primate species that has provided much insight into studies of the primate placenta, maternal condition, and metabolic programming, yet the relationships between maternal weight and placental DNAm are unknown. Here,…
Feasibility of fecal microbiota transplantation via oral gavage to safely alter gut microbiome composition in marmosets
Disruption of microbial communities within human hosts has been associated with infection, obesity, cognitive decline, cancer risk and frailty, suggesting that microbiome‐targeted therapies may be an option for improving healthspan and lifespan. The objectives of this study were to determine the feasibility of delivering fecal microbiota transplants (FMTs) to marmosets via oral gavage and to evaluate if alteration of the gut microbiome post‐FMT c…
Age‐related changes in hematological biomarkers in common marmosets
Researchers and veterinarians often use hematology and clinical chemistry to evaluate animal health. These biomarkers are relatively easy to obtain, and understanding how they change across healthy aging is critical to clinical care and diagnostics for these animals. We aimed to evaluate how clinical biomarkers from a chemistry profile and complete blood count (CBC) change with age in common marmosets ( Callithrix jacchus ). We assessed blood sam…
Genetic characterization of a captive marmoset ( Callithrix jacchus ) colony using genotype‐by‐sequencing
The marmoset is a fundamental nonhuman primate model for the study of aging, neurobiology, and many other topics. Genetic management of captive marmoset colonies is complicated by frequent chimerism in the blood and other tissues, a lack of tools to enable cost‐effective, genome‐wide interrogation of variation, and historic mergers and migrations of animals between colonies. We implemented genotype‐by‐sequencing (GBS) of hair follicle derived DNA…
Validation of Body Condition Scoring as a Screening Test for Low Body Condition and Obesity in Common Marmosets ( Callithrix jacchus )
Assessing body weight is common practice for monitoring health in common marmosets ( Callithrix jacchus ). Body composition analysis via quantitative magnetic resonance (QMR) is a more in‐depth assessment allowing measurements of lean and fat mass, but it is expensive and remains unavailable to most. Alternatively, body condition scoring (BCS) is an instrument‐free method for visually inspecting and palpating lean and fat tissue. Animals are rate…
Biology (20 obras) · Callithrix (16 obras) · Marmoset (16 obras) · Ecology (12 obras) · Primate Behavior and Ecology (11 obras) · Genetics (9 obras) · Medicine (9 obras) · Physiology (9 obras) · Zoology (7 obras) · Internal Medicine (6 obras)