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Susanne R de Rooij

Datos Biográficos

ID5225091
NOMBRESusanne R de Rooij
NOMBRESSusanne R
APELLIDOde Rooij
FIRMADE ROOIJ S R
AFILIACIONESAmsterdam University Medical Centers
ORCID0000-0001-7382-5749
VERIFICADOSí
TOTAL DE OBRAS19
TOTAL DE CITAS4
TOTAL COMO AUTOR19
TOTAL COMO EDITOR0
PRIMER AÑO DE PUBLICACIÓN2006
AÑO MÁS RECIENTE DE PUBLICACIÓN2026
ÍNDICE H1
  • The Role of Discrimination in Social Safety and its Interplay with Adolescents’ Mental Health and Substance Use

    Open Access•Hanan Bozhar, Susanne R de Rooij et al.•ARTICLE•Journal of Youth and Adolescence•2026•Referencias: 56

    Discrimination, as experienced by adolescents, represents a major societal issue with implications for mental health and risky health behaviors. Yet the interplay between these factors in the context of social safety in urban living environments remains insufficiently understood and was explored in the current study. Participants were 1,675 Dutch adolescents (Mage = 17.44 years, SD = 0.36; 56.6% girls) who participated in the ABCD-study. This sub…

  • Understanding Affective Symptoms and Substance Use in Older Adolescents in an Urban Context

    Open Access•Hanan Bozhar, Susanne R de Rooij et al.•ARTICLE•International Journal of Mental…•2025

    Global urbanization may present mental health challenges for youth. We investigated relationships between affective symptoms, substance use, and urban characteristics in 17–18-year-old adolescents from the Amsterdam Born Children and their Development study ( N = 1682). Objectively measured urban neighbourhood characteristics (e.g. safety, poverty) were obtained from the Geoscience and Health Cohort Consortium in addition to self-report assessmen…

  • Bidirectional associations of problematic social media use and problematic gaming with mental health difficulties and strengths in adolescents

    Open Access•Luka Todorović, Hanan Bozhar et al.•ARTICLE•Journal of Research on Adolescence•2025•Referencias: 2

    The evidence on the direction of associations between mental health and problematic social media use (PSMU) and problematic gaming (PG) in adolescents remains inconclusive. Therefore, this study investigated a comprehensive model of temporal associations between mental health difficulties and strengths, and PSMU/PG, while accounting for sex and perceived social support as potential moderators. Mental health domains were measured with the Strength…

  • Worldwide trends in underweight and obesity from 1990 to 2022

    Open Access•Nowell H Phelps, Rosie Singleton et al.•ARTICLE•The Lancet•2024

    BACKGROUND: Underweight and obesity are associated with adverse health outcomes throughout the life course. We estimated the individual and combined prevalence of underweight or thinness and obesity, and their changes, from 1990 to 2022 for adults and school-aged children and adolescents in 200 countries and territories. METHODS: ). For school-aged children and adolescents, we report thinness (BMI 2 SD above the median). FINDINGS: From 1990 to 20…

  • Associations Between Early-Pregnancy Vitamin D Status and Postpartum Depressive and Anxiety Symptoms

    Open Access•Desirée Domacassé, Susanne R de Rooij et al.•ARTICLE•Psychosomatic Medicine•2024

    OBJECTIVE: Maternal postpartum depressive and anxiety symptoms are risk factors for subsequent maternal and child mental health problems. Little is known about the potential role of antepartum vitamin D and C-reactive protein (CRP) in the etiology of maternal postpartum affective symptoms. We investigated associations between antepartum vitamin D status and postpartum depressive and anxiety symptoms and whether antepartum CRP mediated these assoc…

  • Daily stair climbing is associated with decreased risk for the metabolic syndrome

    Open Access•Anna C Whittaker, Frank F Eves et al.•ARTICLE•BMC Public Health•2021

    The most likely explanation for the current findings is that daily stair climbing may be protective against the metabolic syndrome. This result reinforces public health recommendations for increased stair climbing with evidence from physiological outcomes

  • Height and body-mass index trajectories of school-aged children and adolescents from 1985 to 2019 in 200 countries and territories

    Open Access•Andrea Rodriguez-Martinez, Andrea Rodriguez‐Martinez et al.•ARTICLE•The Lancet•2020

    BACKGROUND: Comparable global data on health and nutrition of school-aged children and adolescents are scarce. We aimed to estimate age trajectories and time trends in mean height and mean body-mass index (BMI), which measures weight gain beyond what is expected from height gain, for school-aged children and adolescents. METHODS: For this pooled analysis, we used a database of cardiometabolic risk factors collated by the Non-Communicable Disease …

  • Prenatal developmental origins of behavior and mental health

    Open Access•Bea Van Den Bergh, Bea R H Van den Bergh et al.•ARTICLE•Neuroscience & Biobehavioral…•2020

  • Associations Between Child Maltreatment, Autonomic Regulation, and Adverse Cardiovascular Outcome in an Urban Population

    Open Access•Maryse J Bakema, Mirjam van Zuiden et al.•ARTICLE•Frontiers in Psychiatry•2020

    In a large, multi-ethnic urban-population cohort study we observed a positive association between number of endorsed child maltreatment types and self-reported aCVO but not autonomic regulation, over and above the effect of relevant demographic, health, and psychological factors. Future studies should examine the potential role of the dynamics of autonomic dysregulation as potential underlying biological pathways in the association between ACEs a…

  • Cognitive Behavioral Therapy for Antenatal Depression in a Pilot Randomized Controlled Trial and Effects on Neurobiological, Behavioral and Cognitive Outcomes in Offspring 3–7 Years Postpartum

    Open Access•Laura S Bleker, Jeannette Milgrom et al.•ARTICLE•Frontiers in Psychiatry•2020

    Our explorative findings suggest that antenatal depression treatment decreases overall child DNA-methylation, increases cortical thickness, and decreases white matter fiber-bundle cross-section in regions involved in cognitive function and the stress response. Nevertheless, larger studies are warranted to confirm our preliminary conclusion that CBT in pregnancy alters neurobiological outcomes in children. Clinical relevance remains unclear as we …

  • The Long-Term Impact of Maternal Anxiety and Depression Postpartum and in Early Childhood on Child and Paternal Mental Health at 11–12 Years Follow-Up

    Open Access•Annika L Walker, Priya H Peters et al.•ARTICLE•Frontiers in Psychiatry•2020

    Our results indicate that fathers and children seem to be affected only to a small extent by maternal postpartum anxiety or depression

  • Rising rural body-mass index is the main driver of the global obesity epidemic in adults

    Open Access•NCD Risk Factor Collaboration, Honor Bixby et al.•ARTICLE•Nature•2019

    Body-mass index (BMI) has increased steadily in most countries in parallel with a rise in the proportion of the population who live in cities 1,2 . This has led to a widely reported view that urbanization is one of the most important drivers of the global rise in obesity 3–6 . Here we use 2,009 population-based studies, with measurements of height and weight in more than 112 million adults, to report national, regional and global trends in mean B…

  • Programming Effects of Prenatal Stress on Neurodevelopment—The Pitfall of Introducing a Self-Fulfilling Prophecy

    Open Access•Laura S Bleker, Susanne R de Rooij et al.•ARTICLE•International Journal of…•2019

    There is increasing interest for the potential harmful effects of prenatal stress on the developing fetal brain, both in scientific literature and in public press. Results from animal studies suggest that gestational stress leads to an altered offspring neurodevelopment with adverse behavioral and cognitive consequences. Furthermore, there are indications in human studies that severe prenatal stress has negative consequences for the child's neuro…

  • Brain Magnetic Resonance Imaging Findings in Children after Antenatal Maternal Depression Treatment, a Longitudinal Study Built on a Pilot Randomized Controlled Trial

    Open Access•Laura S Bleker, Jeannette Milgrom et al.•ARTICLE•International Journal of…•2019

    Antenatal depression is associated with an increased risk of offspring neuro-developmental disorders, potentially as a consequence of an altered brain development in utero . We hypothesized that reducing maternal depression by Cognitive Behavioral Therapy (CBT) during pregnancy may ameliorate the offspring's brain (micro)structural outcomes. 54 pregnant women with a diagnosed clinical depression were randomly allocated to CBT or Treatment as Usua…

  • Prenatal Undernutrition and Autonomic Function in Adulthood

    Susanne R de Rooij, Alexander Jones et al.•ARTICLE•Psychosomatic Medicine•2016

    OBJECTIVES: Early-life adversity has been shown to be associated with cardiovascular disease and mortality in later life, but little is known about the mechanisms that underlie this association. Prenatal undernutrition, a severe early-life stressor, is associated with double the risk of coronary heart disease and increased blood pressure responses to psychological stress. In the present study, we tested the hypothesis that prenatal undernutrition…

  • Cardiovascular and Cortisol Reactions to Acute Psychological Stress and Adiposity

    Anna C Phillips, T J Roseboom et al.•ARTICLE•Psychosomatic Medicine•2012

    OBJECTIVE: In recent analyses of data from a large community sample, negative cross-sectional and prospective associations between cardiac stress reactivity and obesity were observed. The present study reexamined the association between cardiovascular reactivity and adiposity in the Dutch Famine Birth Cohort, with the additional aim of examining the association between cortisol reactivity and adiposity. METHODS: Blood pressure, heart rate, and sa…

  • Sexual Orientation and Gender Identity After Prenatal Exposure to the Dutch Famine

    Open Access•Susanne R de Rooij, Rebecca C Painter et al.•ARTICLE•Archives of Sexual Behavior•2009•Citada por: 4•Referencias: 16

    Sexual differentiation of the human brain has been suggested to take place through exposure to sex steroids during intrauterine development. Animal experiments have shown that interference in this process by underfeeding of the mother can result in feminization of the male offspring. We explored the possible effects of prenatal exposure to famine on sexual orientation and gender identity in humans. We used the Klein Sexual Orientation Grid to ass…

  • The Dutch famine and its long-term consequences for adult health

    Open Access•T J Roseboom, Tessa Roseboom et al.•ARTICLE•Early Human Development•2006

  • A possible link between prenatal exposure to famine and breast cancer

    Open Access•Rebecca C Painter, Susanne R de Rooij et al.•ARTICLE•American Journal of Human Biology•2006

    In a study of 475 women born around the 1944-1945 Dutch famine, women exposed to prenatal famine more often reported a history of breast cancer than nonexposed women (hazard ratio, 2.6; 95% confidence interval, 0.9-7.7). They also had alterations in reproductive risk factors. Prenatal famine may increase breast cancer incidence

  • Sexual Orientation and Gender Identity After Prenatal Exposure to the Dutch Famine

    Open Access•Susanne R de Rooij, Rebecca C Painter et al.•ARTICLE•Archives of Sexual Behavior•2009•Citada por: 4•Referencias: 16

    Sexual differentiation of the human brain has been suggested to take place through exposure to sex steroids during intrauterine development. Animal experiments have shown that interference in this process by underfeeding of the mother can result in feminization of the male offspring. We explored the possible effects of prenatal exposure to famine on sexual orientation and gender identity in humans. We used the Klein Sexual Orientation Grid to ass…

  • The Dutch famine and its long-term consequences for adult health

    Open Access•T J Roseboom, Tessa Roseboom et al.•ARTICLE•Early Human Development•2006

  • A possible link between prenatal exposure to famine and breast cancer

    Open Access•Rebecca C Painter, Susanne R de Rooij et al.•ARTICLE•American Journal of Human Biology•2006

    In a study of 475 women born around the 1944-1945 Dutch famine, women exposed to prenatal famine more often reported a history of breast cancer than nonexposed women (hazard ratio, 2.6; 95% confidence interval, 0.9-7.7). They also had alterations in reproductive risk factors. Prenatal famine may increase breast cancer incidence

  • Sexual Orientation and Gender Identity After Prenatal Exposure to the Dutch Famine

    Open Access•Susanne R de Rooij, Rebecca C Painter et al.•ARTICLE•Archives of Sexual Behavior•2009•Citada por: 4•Referencias: 16

    Sexual differentiation of the human brain has been suggested to take place through exposure to sex steroids during intrauterine development. Animal experiments have shown that interference in this process by underfeeding of the mother can result in feminization of the male offspring. We explored the possible effects of prenatal exposure to famine on sexual orientation and gender identity in humans. We used the Klein Sexual Orientation Grid to ass…

  • Cardiovascular and Cortisol Reactions to Acute Psychological Stress and Adiposity

    Anna C Phillips, T J Roseboom et al.•ARTICLE•Psychosomatic Medicine•2012

    OBJECTIVE: In recent analyses of data from a large community sample, negative cross-sectional and prospective associations between cardiac stress reactivity and obesity were observed. The present study reexamined the association between cardiovascular reactivity and adiposity in the Dutch Famine Birth Cohort, with the additional aim of examining the association between cortisol reactivity and adiposity. METHODS: Blood pressure, heart rate, and sa…

  • Prenatal Undernutrition and Autonomic Function in Adulthood

    Susanne R de Rooij, Alexander Jones et al.•ARTICLE•Psychosomatic Medicine•2016

    OBJECTIVES: Early-life adversity has been shown to be associated with cardiovascular disease and mortality in later life, but little is known about the mechanisms that underlie this association. Prenatal undernutrition, a severe early-life stressor, is associated with double the risk of coronary heart disease and increased blood pressure responses to psychological stress. In the present study, we tested the hypothesis that prenatal undernutrition…

  • Rising rural body-mass index is the main driver of the global obesity epidemic in adults

    Open Access•NCD Risk Factor Collaboration, Honor Bixby et al.•ARTICLE•Nature•2019

    Body-mass index (BMI) has increased steadily in most countries in parallel with a rise in the proportion of the population who live in cities 1,2 . This has led to a widely reported view that urbanization is one of the most important drivers of the global rise in obesity 3–6 . Here we use 2,009 population-based studies, with measurements of height and weight in more than 112 million adults, to report national, regional and global trends in mean B…

  • Programming Effects of Prenatal Stress on Neurodevelopment—The Pitfall of Introducing a Self-Fulfilling Prophecy

    Open Access•Laura S Bleker, Susanne R de Rooij et al.•ARTICLE•International Journal of…•2019

    There is increasing interest for the potential harmful effects of prenatal stress on the developing fetal brain, both in scientific literature and in public press. Results from animal studies suggest that gestational stress leads to an altered offspring neurodevelopment with adverse behavioral and cognitive consequences. Furthermore, there are indications in human studies that severe prenatal stress has negative consequences for the child's neuro…

  • Brain Magnetic Resonance Imaging Findings in Children after Antenatal Maternal Depression Treatment, a Longitudinal Study Built on a Pilot Randomized Controlled Trial

    Open Access•Laura S Bleker, Jeannette Milgrom et al.•ARTICLE•International Journal of…•2019

    Antenatal depression is associated with an increased risk of offspring neuro-developmental disorders, potentially as a consequence of an altered brain development in utero . We hypothesized that reducing maternal depression by Cognitive Behavioral Therapy (CBT) during pregnancy may ameliorate the offspring's brain (micro)structural outcomes. 54 pregnant women with a diagnosed clinical depression were randomly allocated to CBT or Treatment as Usua…

  • Height and body-mass index trajectories of school-aged children and adolescents from 1985 to 2019 in 200 countries and territories

    Open Access•Andrea Rodriguez-Martinez, Andrea Rodriguez‐Martinez et al.•ARTICLE•The Lancet•2020

    BACKGROUND: Comparable global data on health and nutrition of school-aged children and adolescents are scarce. We aimed to estimate age trajectories and time trends in mean height and mean body-mass index (BMI), which measures weight gain beyond what is expected from height gain, for school-aged children and adolescents. METHODS: For this pooled analysis, we used a database of cardiometabolic risk factors collated by the Non-Communicable Disease …

  • Prenatal developmental origins of behavior and mental health

    Open Access•Bea Van Den Bergh, Bea R H Van den Bergh et al.•ARTICLE•Neuroscience & Biobehavioral…•2020

  • Associations Between Child Maltreatment, Autonomic Regulation, and Adverse Cardiovascular Outcome in an Urban Population

    Open Access•Maryse J Bakema, Mirjam van Zuiden et al.•ARTICLE•Frontiers in Psychiatry•2020

    In a large, multi-ethnic urban-population cohort study we observed a positive association between number of endorsed child maltreatment types and self-reported aCVO but not autonomic regulation, over and above the effect of relevant demographic, health, and psychological factors. Future studies should examine the potential role of the dynamics of autonomic dysregulation as potential underlying biological pathways in the association between ACEs a…

  • Cognitive Behavioral Therapy for Antenatal Depression in a Pilot Randomized Controlled Trial and Effects on Neurobiological, Behavioral and Cognitive Outcomes in Offspring 3–7 Years Postpartum

    Open Access•Laura S Bleker, Jeannette Milgrom et al.•ARTICLE•Frontiers in Psychiatry•2020

    Our explorative findings suggest that antenatal depression treatment decreases overall child DNA-methylation, increases cortical thickness, and decreases white matter fiber-bundle cross-section in regions involved in cognitive function and the stress response. Nevertheless, larger studies are warranted to confirm our preliminary conclusion that CBT in pregnancy alters neurobiological outcomes in children. Clinical relevance remains unclear as we …

  • The Long-Term Impact of Maternal Anxiety and Depression Postpartum and in Early Childhood on Child and Paternal Mental Health at 11–12 Years Follow-Up

    Open Access•Annika L Walker, Priya H Peters et al.•ARTICLE•Frontiers in Psychiatry•2020

    Our results indicate that fathers and children seem to be affected only to a small extent by maternal postpartum anxiety or depression

  • Daily stair climbing is associated with decreased risk for the metabolic syndrome

    Open Access•Anna C Whittaker, Frank F Eves et al.•ARTICLE•BMC Public Health•2021

    The most likely explanation for the current findings is that daily stair climbing may be protective against the metabolic syndrome. This result reinforces public health recommendations for increased stair climbing with evidence from physiological outcomes

  • Worldwide trends in underweight and obesity from 1990 to 2022

    Open Access•Nowell H Phelps, Rosie Singleton et al.•ARTICLE•The Lancet•2024

    BACKGROUND: Underweight and obesity are associated with adverse health outcomes throughout the life course. We estimated the individual and combined prevalence of underweight or thinness and obesity, and their changes, from 1990 to 2022 for adults and school-aged children and adolescents in 200 countries and territories. METHODS: ). For school-aged children and adolescents, we report thinness (BMI 2 SD above the median). FINDINGS: From 1990 to 20…

  • Associations Between Early-Pregnancy Vitamin D Status and Postpartum Depressive and Anxiety Symptoms

    Open Access•Desirée Domacassé, Susanne R de Rooij et al.•ARTICLE•Psychosomatic Medicine•2024

    OBJECTIVE: Maternal postpartum depressive and anxiety symptoms are risk factors for subsequent maternal and child mental health problems. Little is known about the potential role of antepartum vitamin D and C-reactive protein (CRP) in the etiology of maternal postpartum affective symptoms. We investigated associations between antepartum vitamin D status and postpartum depressive and anxiety symptoms and whether antepartum CRP mediated these assoc…

  • Understanding Affective Symptoms and Substance Use in Older Adolescents in an Urban Context

    Open Access•Hanan Bozhar, Susanne R de Rooij et al.•ARTICLE•International Journal of Mental…•2025

    Global urbanization may present mental health challenges for youth. We investigated relationships between affective symptoms, substance use, and urban characteristics in 17–18-year-old adolescents from the Amsterdam Born Children and their Development study ( N = 1682). Objectively measured urban neighbourhood characteristics (e.g. safety, poverty) were obtained from the Geoscience and Health Cohort Consortium in addition to self-report assessmen…

  • Bidirectional associations of problematic social media use and problematic gaming with mental health difficulties and strengths in adolescents

    Open Access•Luka Todorović, Hanan Bozhar et al.•ARTICLE•Journal of Research on Adolescence•2025•Referencias: 2

    The evidence on the direction of associations between mental health and problematic social media use (PSMU) and problematic gaming (PG) in adolescents remains inconclusive. Therefore, this study investigated a comprehensive model of temporal associations between mental health difficulties and strengths, and PSMU/PG, while accounting for sex and perceived social support as potential moderators. Mental health domains were measured with the Strength…

  • The Role of Discrimination in Social Safety and its Interplay with Adolescents’ Mental Health and Substance Use

    Open Access•Hanan Bozhar, Susanne R de Rooij et al.•ARTICLE•Journal of Youth and Adolescence•2026•Referencias: 56

    Discrimination, as experienced by adolescents, represents a major societal issue with implications for mental health and risky health behaviors. Yet the interplay between these factors in the context of social safety in urban living environments remains insufficiently understood and was explored in the current study. Participants were 1,675 Dutch adolescents (Mage = 17.44 years, SD = 0.36; 56.6% girls) who participated in the ABCD-study. This sub…

Medicine (15 obras) · Pregnancy (9 obras) · Psychology (9 obras) · Birth, Development, and Health (7 obras) · Clinical Psychology (7 obras) · Internal Medicine (7 obras) · Maternal Mental Health During Pregnancy and Postpartum (7 obras) · Psychiatry (7 obras) · Demography (6 obras) · Biology (5 obras)

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