Alan Shihadeh
Datos Biográficos
| ID | 5378150 |
|---|---|
| NOMBRE | Alan Shihadeh |
| NOMBRES | Alan |
| APELLIDO | Shihadeh |
| FIRMA | SHIHADEH A |
| AFILIACIONES | American University of Beirut |
| ORCID | 0000-0001-6387-8564 |
| VERIFICADO | Sí |
| TOTAL DE OBRAS | 20 |
| TOTAL DE CITAS | 2 |
| OBRAS COMO AUTOR | 20 |
| OBRAS COMO EDITOR | 0 |
| PRIMER AÑO DE PUBLICACIÓN | 2011 |
| AÑO MÁS RECIENTE DE PUBLICACIÓN | 2024 |
| ÍNDICE H | 1 |
Effects of freebase/protonated nicotine concentration, liquid composition and electrical power on throat hit in direct-to-lung vaping
Nicotine throat hit can be predicted and manipulated through ENDS device and liquid design variables. Regulating ENDS throat hit is feasible and may help reduce product appeal to nicotine-naïve individuals while maintaining acceptability for smokers
Impact of smoking intensity and device cleaning on Iqos emissions
This study showed that puffing parameters, but not device cleaning, have significant effects on carbonyl, phenol and other emissions. Data analysis highlighted the importance of comparing IQOS emissions with an array of commercial cigarettes tested under different puffing regimes before accepting reduced exposure claims
Comparison of design characteristics and toxicant emissions from Vuse Solo and Alto electronic nicotine delivery systems
Vuse Solo is an above-Ohm ENDS that emits approximately one-third the nicotine flux of a Marlboro Red cigarette (129 μg/s) and considerably lower CC and ROS yields than a combustible cigarette. With its higher power, the nicotine flux and ROS yield from Alto are similar to Marlboro Red levels; Alto may thus present greater abuse liability than the lower sales-volume Solo
Levels of menthol, nicotine and cooling agents measured in Juul products purchased across a three-year period
This study highlights how regulations intended to reduce e-cigarette prevalence among youth may influence changes in tobacco product characteristics in ways that regulators may not have foreseen
Assessing toxicant emissions from e-liquids with DIY additives used in response to a potential flavour ban in e-cigarettes
This study showed that DIY additives can impact aerosol toxicant emissions from e-cigarettes and should be considered by policymakers when restricting commercially available flavoured e-liquids
Juul ‘new technology’ pods exhibit greater electrical power and nicotine output than previous devices
In 2019, JUUL Labs began marketing in the European Union 'new technology' pods that incorporated a new wick that it claimed provided 'more satisfaction'. In this study, we compared design and materials of construction, electrical characteristics, liquid composition and nicotine and carbonyl emissions of new technology JUUL pods to their predecessors. Consistent with manufacturer's claims, we found that the new pods incorporated a different wickin…
Electrical features, liquid composition and toxicant emissions from ‘pod-mod’-like disposable electronic cigarettes
Disposable e-cigarettes are designed with high nicotine concentration liquids and are capable of emitting much higher nicotine and carbonyl species relative to rechargeable look-alike e-cigarettes. These differences are likely due to the lower quality in construction, unreliable labelling and lack of temperature control regulation that limits the power during operation. From a public health perspective, regulating these devices is important to li…
Effects of flavourants and humectants on waterpipe tobacco puffing behaviour, biomarkers of exposure and subjective effects among adults with high versus low nicotine dependence
Findings underscore the complexity of setting product standards related to flavourants and humectants in WT. Future research evaluating whether WT smokers with high dependence would quit or reduce their WT smoking in response to removal of flavourants or humectants from WT is necessary to appreciate the full public health effects of such policies
Impact of flavors and humectants on waterpipe tobacco smoking topography, subjective effects, toxicant exposure and intentions for continued use
The findings demonstrate the importance of flavours and humectants on improving WT smoking experience and increasing the likelihood that users will want to initiate and continue smoking. Moreover, it demonstrates that flavours and humectants influence smoking behaviour and toxicant exposure in some unexpected ways that are important for regulatory efforts
Open-System’ electronic cigarettes cannot be regulated effectively
Electronic cigarettes (ECIGs) are a class of products that use an electrically powered heating element to aerosolise a liquid for user inhalation. One subgroup of the class, ‘closed-system’ ECIGs, is sold ready-to-use and is constructed of component parts that cannot be modified readily and are filled with liquids that cannot be accessed easily. Another subgroup of the class, ‘open-system’ ECIGs, allows the user to modify virtually every componen…
Philip Morris patents ‘harm reduction’ electronic waterpipe
On 18 April 2019, a patent filed by Philip Morris Products SA was published entitled ‘Shisha device for heating a substrate without combustion’.1 The patent describes a waterpipe apparatus that contains a complex electric heating element with a cartridge containing an ‘aerosol-generating substrate’.1 The design appears to interchangeably accommodate solid or liquid substrates that may or may not contain tobacco, non-tobacco plant material or nico…
Invalidity of an Oft-Cited Estimate of the Relative Harms of Electronic Cigarettes
Pictorial health warning labels on the waterpipe device are effective in reducing smoking satisfaction, puffing behaviour and exposure to CO
This pilot study shows that placing HWL on the WP device is effective in reducing WP smoker's positive experiences, puffing parameters and exposure to carbon monoxide. HWLs lead also to more appreciation of WP harmful effects, making them a promising regulatory approach for addressing the spread of WP smoking among young adults in the USA
Characteristics and toxicant emissions of Juul electronic cigarettes
JUUL emits a high-nicotine concentration aerosol predominantly in the protonated form. JUUL's nicotine-normalised formaldehyde and total aldehyde yields are lower than other previously studied ECIGs and combustible cigarettes
Answering questions about electronic cigarettes using a multidisciplinary model
Electronic cigarettes (ECIGs) are a relatively new class of tobacco products and a subject of much debate for scientists and policymakers worldwide. Objective data that address the ECIG risk-benefit ratio for individual and public health are needed, and addressing this need requires a multidisciplinary approach that spans several areas of psychology as well as chemistry, toxicant inhalation, and physiology. This multidisciplinary approach would b…
Toxicant inhalation among singleton waterpipe tobacco users in natural settings
Background Studies that assess waterpipe tobacco smoking behaviour and toxicant exposure generally use controlled laboratory environments with small samples that may not fully capture real-world variability in human behaviour and waterpipe products. This study aimed to conduct real-time sampling of waterpipe tobacco use in natural environments using an in situ device. Methods We used the REALTIME sampling instrument: a validated, portable, self-p…
Comparison of a preferred versus non-preferred waterpipe tobacco flavour
The current study is the first to examine flavours in WP smoking by measuring preferred versus control preparations to understand the impact on subjective experience, smoking behaviour and toxicant exposure. The pattern of results suggests that even this relatively minor manipulation resulted in significant changes in subjective experience. These results indicate a possible need for regulations restricting flavours in WP tobacco as with combustib…
Electronic cigarette nicotine delivery can exceed that of combustible cigarettes
This study demonstrates a relationship between ECIG liquid nicotine concentration and user plasma nicotine concentration in experienced ECIG users. Nicotine delivery from some ECIGs may exceed that of a combustible cigarette. The rationale for this higher level of nicotine delivery is uncertain
A comparative study of systemic carcinogen exposure in waterpipe smokers, cigarette smokers and non-smokers
These results provide the clearest indication to date about systemic exposure to harmful carcinogens associated with long-term waterpipe smoking. Such evidence can support policy and regulatory efforts designed to confront the emerging global waterpipe epidemic, as well as drive interventions aimed at increasing the public awareness about the cancer risk associated with waterpipe smoking
Waterpipe tobacco products
Nicotine labelling on waterpipe tobacco products does not reflect delivery; smoking a brand with a "0.05% nicotine" label led to greater plasma nicotine levels than smoking a brand with a "0.5% nicotine" label. Waterpipe tobacco products should be labelled in a manner that does not mislead consumers
Invalidity of an Oft-Cited Estimate of the Relative Harms of Electronic Cigarettes
Answering questions about electronic cigarettes using a multidisciplinary model
Electronic cigarettes (ECIGs) are a relatively new class of tobacco products and a subject of much debate for scientists and policymakers worldwide. Objective data that address the ECIG risk-benefit ratio for individual and public health are needed, and addressing this need requires a multidisciplinary approach that spans several areas of psychology as well as chemistry, toxicant inhalation, and physiology. This multidisciplinary approach would b…
Waterpipe tobacco products
Nicotine labelling on waterpipe tobacco products does not reflect delivery; smoking a brand with a "0.05% nicotine" label led to greater plasma nicotine levels than smoking a brand with a "0.5% nicotine" label. Waterpipe tobacco products should be labelled in a manner that does not mislead consumers
A comparative study of systemic carcinogen exposure in waterpipe smokers, cigarette smokers and non-smokers
These results provide the clearest indication to date about systemic exposure to harmful carcinogens associated with long-term waterpipe smoking. Such evidence can support policy and regulatory efforts designed to confront the emerging global waterpipe epidemic, as well as drive interventions aimed at increasing the public awareness about the cancer risk associated with waterpipe smoking
Electronic cigarette nicotine delivery can exceed that of combustible cigarettes
This study demonstrates a relationship between ECIG liquid nicotine concentration and user plasma nicotine concentration in experienced ECIG users. Nicotine delivery from some ECIGs may exceed that of a combustible cigarette. The rationale for this higher level of nicotine delivery is uncertain
Comparison of a preferred versus non-preferred waterpipe tobacco flavour
The current study is the first to examine flavours in WP smoking by measuring preferred versus control preparations to understand the impact on subjective experience, smoking behaviour and toxicant exposure. The pattern of results suggests that even this relatively minor manipulation resulted in significant changes in subjective experience. These results indicate a possible need for regulations restricting flavours in WP tobacco as with combustib…
Toxicant inhalation among singleton waterpipe tobacco users in natural settings
Background Studies that assess waterpipe tobacco smoking behaviour and toxicant exposure generally use controlled laboratory environments with small samples that may not fully capture real-world variability in human behaviour and waterpipe products. This study aimed to conduct real-time sampling of waterpipe tobacco use in natural environments using an in situ device. Methods We used the REALTIME sampling instrument: a validated, portable, self-p…
Pictorial health warning labels on the waterpipe device are effective in reducing smoking satisfaction, puffing behaviour and exposure to CO
This pilot study shows that placing HWL on the WP device is effective in reducing WP smoker's positive experiences, puffing parameters and exposure to carbon monoxide. HWLs lead also to more appreciation of WP harmful effects, making them a promising regulatory approach for addressing the spread of WP smoking among young adults in the USA
Characteristics and toxicant emissions of Juul electronic cigarettes
JUUL emits a high-nicotine concentration aerosol predominantly in the protonated form. JUUL's nicotine-normalised formaldehyde and total aldehyde yields are lower than other previously studied ECIGs and combustible cigarettes
Answering questions about electronic cigarettes using a multidisciplinary model
Electronic cigarettes (ECIGs) are a relatively new class of tobacco products and a subject of much debate for scientists and policymakers worldwide. Objective data that address the ECIG risk-benefit ratio for individual and public health are needed, and addressing this need requires a multidisciplinary approach that spans several areas of psychology as well as chemistry, toxicant inhalation, and physiology. This multidisciplinary approach would b…
Impact of flavors and humectants on waterpipe tobacco smoking topography, subjective effects, toxicant exposure and intentions for continued use
The findings demonstrate the importance of flavours and humectants on improving WT smoking experience and increasing the likelihood that users will want to initiate and continue smoking. Moreover, it demonstrates that flavours and humectants influence smoking behaviour and toxicant exposure in some unexpected ways that are important for regulatory efforts
Open-System’ electronic cigarettes cannot be regulated effectively
Electronic cigarettes (ECIGs) are a class of products that use an electrically powered heating element to aerosolise a liquid for user inhalation. One subgroup of the class, ‘closed-system’ ECIGs, is sold ready-to-use and is constructed of component parts that cannot be modified readily and are filled with liquids that cannot be accessed easily. Another subgroup of the class, ‘open-system’ ECIGs, allows the user to modify virtually every componen…
Philip Morris patents ‘harm reduction’ electronic waterpipe
On 18 April 2019, a patent filed by Philip Morris Products SA was published entitled ‘Shisha device for heating a substrate without combustion’.1 The patent describes a waterpipe apparatus that contains a complex electric heating element with a cartridge containing an ‘aerosol-generating substrate’.1 The design appears to interchangeably accommodate solid or liquid substrates that may or may not contain tobacco, non-tobacco plant material or nico…
Invalidity of an Oft-Cited Estimate of the Relative Harms of Electronic Cigarettes
Juul ‘new technology’ pods exhibit greater electrical power and nicotine output than previous devices
In 2019, JUUL Labs began marketing in the European Union 'new technology' pods that incorporated a new wick that it claimed provided 'more satisfaction'. In this study, we compared design and materials of construction, electrical characteristics, liquid composition and nicotine and carbonyl emissions of new technology JUUL pods to their predecessors. Consistent with manufacturer's claims, we found that the new pods incorporated a different wickin…
Electrical features, liquid composition and toxicant emissions from ‘pod-mod’-like disposable electronic cigarettes
Disposable e-cigarettes are designed with high nicotine concentration liquids and are capable of emitting much higher nicotine and carbonyl species relative to rechargeable look-alike e-cigarettes. These differences are likely due to the lower quality in construction, unreliable labelling and lack of temperature control regulation that limits the power during operation. From a public health perspective, regulating these devices is important to li…
Effects of flavourants and humectants on waterpipe tobacco puffing behaviour, biomarkers of exposure and subjective effects among adults with high versus low nicotine dependence
Findings underscore the complexity of setting product standards related to flavourants and humectants in WT. Future research evaluating whether WT smokers with high dependence would quit or reduce their WT smoking in response to removal of flavourants or humectants from WT is necessary to appreciate the full public health effects of such policies
Levels of menthol, nicotine and cooling agents measured in Juul products purchased across a three-year period
This study highlights how regulations intended to reduce e-cigarette prevalence among youth may influence changes in tobacco product characteristics in ways that regulators may not have foreseen
Assessing toxicant emissions from e-liquids with DIY additives used in response to a potential flavour ban in e-cigarettes
This study showed that DIY additives can impact aerosol toxicant emissions from e-cigarettes and should be considered by policymakers when restricting commercially available flavoured e-liquids
Impact of smoking intensity and device cleaning on Iqos emissions
This study showed that puffing parameters, but not device cleaning, have significant effects on carbonyl, phenol and other emissions. Data analysis highlighted the importance of comparing IQOS emissions with an array of commercial cigarettes tested under different puffing regimes before accepting reduced exposure claims
Comparison of design characteristics and toxicant emissions from Vuse Solo and Alto electronic nicotine delivery systems
Vuse Solo is an above-Ohm ENDS that emits approximately one-third the nicotine flux of a Marlboro Red cigarette (129 μg/s) and considerably lower CC and ROS yields than a combustible cigarette. With its higher power, the nicotine flux and ROS yield from Alto are similar to Marlboro Red levels; Alto may thus present greater abuse liability than the lower sales-volume Solo
Effects of freebase/protonated nicotine concentration, liquid composition and electrical power on throat hit in direct-to-lung vaping
Nicotine throat hit can be predicted and manipulated through ENDS device and liquid design variables. Regulating ENDS throat hit is feasible and may help reduce product appeal to nicotine-naïve individuals while maintaining acceptability for smokers
Smoking Behavior and Cessation (17 obras) · Medicine (15 obras) · Nicotine (14 obras) · Chemistry (12 obras) · Psychology (9 obras) · Internal Medicine (8 obras) · Indoor Air Quality and Microbial Exposure (7 obras) · Electronic cigarette (6 obras) · Food Science (6 obras) · Business (5 obras)