Julian Little
Datos Biográficos
| ID | 5408548 |
|---|---|
| NOMBRE | Julian Little |
| NOMBRES | Julian |
| APELLIDO | Little |
| FIRMA | LITTLE J |
| AFILIACIONES | University of Ottawa |
| ORCID | 0000-0001-5026-5531 |
| VERIFICADO | Sí |
| TOTAL DE OBRAS | 29 |
| TOTAL DE CITAS | 6 |
| TOTAL COMO AUTOR | 29 |
| TOTAL COMO EDITOR | 0 |
| PRIMER AÑO DE PUBLICACIÓN | 1978 |
| AÑO MÁS RECIENTE DE PUBLICACIÓN | 2026 |
| ÍNDICE H | 1 |
Folate and global health
Folate and global health review series, part 4
Background: Autoimmune diseases and bone density loss (osteopenia and osteoporosis) are chronic conditions of complex aetiology that affect diverse populations. Folate may be associated with a higher risk of these disorders due to its essential role in one-carbon metabolism required for nucleotide synthesis, homocysteine metabolism, and methylation processes. However, the evidence on this association is inconclusive. Methods: We searched MEDLINE,…
Evaluating the perceived outcome and impact of an integrated knowledge translation approach in the development of an equity reporting guideline
Integrated knowledge translation (IKT) involves active engagement of knowledge users in co-producing research, ensuring their perspectives shape study design, analysis, and reporting. This can strengthen justice, equity, diversity, and inclusion (JEDI) considerations. We adopted an IKT approach in developing STROBE-Equity, an equity-focused reporting guidelin extension. The perceived value of embedding JEDI principles in reporting guideline devel…
Folate and global health umbrella review series, part 1
Background: Folate is essential for normal growth and in human health throughout the lifecycle. Clinical deficiency of folate impairs DNA synthesis and results in megaloblastic anaemia, while suboptimal folate status before and in early pregnancy results in an elevated risk of neural tube defects (NTD). The evidence on the association of folate status with other health outcomes is largely fragmented and understudied. We conducted a series of umbr…
Folate and global health review series, part 3
Background: Cardiovascular and metabolic diseases account for an increasing share of morbidity and mortality globally. Folic acid supplementation has been linked to a lowered risk of stroke and some metabolic indicators due to its involvement in homocysteine and one-carbon metabolism and its role in the production of nitric oxide; however, the evidence on these associations is inconclusive. Methods: We searched MEDLINE, Embase, CINAHL, the Cochra…
Folate and global health umbrella review series, part 2
Background: Folate has been examined extensively in relation to carcinogenesis due to its role in one-carbon metabolism impacting the synthesis of DNA and RNA, methylation processes, and genomic integrity. Current evidence on the relationship between folate status and the risk of cancer is equivocal: low or deficient folate status may contribute to an increased risk of cancers, while high-dose folic acid supplementation may have adverse effects o…
Exploring perspectives of knowledge users about reporting on health equity in observational studies
BACKGROUND: Health inequities arising from systemic factors and contextual conditions result in avoidable and unjust differences in health outcomes, with profound social and economic implications. Health inequities can frequently go unreported in observational studies. Observational studies can uniquely inform how we understand and address persisting health inequities through collecting, reporting and analyzing health equity factors using 'inclus…
Mejorar la comunicación sobre la equidad en la salud en la investigación observacional (STROBE Equidad)
Melhorando a apresentação de informações sobre equidade em saúde em pesquisas observacionais (STROBE-Equity)
Clinical and serological predictors of post Covid-19 condition–findings from a Canadian prospective cohort study
Introduction More than 3 years into the pandemic, there is persisting uncertainty as to the etiology, biomarkers, and risk factors of Post COVID-19 Condition (PCC). Serological research data remain a largely untapped resource. Few studies have investigated the potential relationships between post-acute serology and PCC, while accounting for clinical covariates. Methods We compared clinical and serological predictors among COVID-19 survivors with …
Reporting of equity in observational epidemiology
Background: Observational studies can inform how we understand and address persisting health inequities through the collection, reporting and analysis of health equity factors. However, the extent to which the analysis and reporting of equity-relevant aspects in observational research are generally unknown. Thus, we aimed to systematically evaluate how equity-relevant observational studies reported equity considerations in the study design and an…
A systematic review of the effect of performance-based financing interventions on out-of-pocket expenses to improve access to, and the utilization of, maternal health services across health sectors in…
Improving social justice in observational studies
Achieving global imperatives such as the Sustainable Development Goals (e.g., SDG 10 Reduced inequalities, SDG 3 Good health and wellbeing) requires advancing health equity in research. The implementation of the STROBE-Equity guidelines will enable a better awareness and understanding of health inequities through better reporting. We will broadly disseminate the reporting guideline with tools to enable adoption and use by journal editors, authors…
Examining the Implementation of the Performance-Based Financing Equity Strategy in Improving Access and Utilization of Maternal Health Services in Cameroon
Performance-based financing (PBF)-a supply-side strategy that incentivizes health providers based on predefined quality and quantity criteria-introduced an innovative approach to reaching the poor by means of using PBF equity instruments. These PBF equity instruments include paying providers more to reach out to poor women, selecting services used by the poor, subsidizing user fees to reduce out-of-pocket expenses, and adding complementary demand…
Improving Social Justice in Covid-19 Health Research
The COVID-19 pandemic has highlighted the global imperative to address health inequities. Observational studies are a valuable source of evidence for real-world effects and impacts of implementing COVID-19 policies on the redistribution of inequities. We assembled a diverse global multi-disciplinary team to develop interim guidance for improving transparency in reporting health equity in COVID-19 observational studies. We identified 14 areas in t…
Stillbirth in Canada
The archaic definition and registration processes for stillbirth currently prevalent in Canada impede both clinical care and public health. The situation is fraught because of definitional problems related to the inclusion of induced abortions at ≥20 weeks’ gestation as stillbirths: widespread uptake of prenatal diagnosis and induced abortion for serious congenital anomalies has resulted in an artefactual temporal increase in stillbirth rates in …
They Should Be Asking Us”
In this study, we examine from multiple perspectives, women's shared decision-making needs when considering cervical screening options: Pap testing, in-clinic human papillomavirus (HPV) testing, self-collected HPV testing, or no screening. The Ottawa Decision Support Framework guided the development of the interview schedule. We conducted semi-structured interviews with seven screen-eligible women and five health care professionals (three health …
Expectations and values about expanded newborn screening
OBJECTIVES: Newborn bloodspot screening (NBS) panels have expanded to include conditions for which treatment effects are less certain, creating debate about population-based screening criteria. We investigated Canadian public expectations and values regarding the types of conditions that should be included in NBS and whether parents should provide consent. METHODS: Eight focus groups (FG; n = 60) included education, deliberative discussion and pr…
Long-Term Worries after Colposcopy
Strategies for Increasing Cervical Cancer Screening Amongst First Nations Communities in Northwest Ontario, Canada
The high burden of cervical cancer in Indigenous populations worldwide is due to underscreening and inadequate follow-up. Using qualitative, participatory action research, we interviewed health care staff to identify ways to increase screening recruitment in First Nations communities in Northwest Ontario, Canada. Our findings suggest the value of a multilevel social-ecological model to promote behavioral changes at the community, health care serv…
A vision for chronic disease prevention and intervention research
A Qualitative Study of Provider Perspectives of Structural Barriers to Cervical Cancer Screening Among First Nations Women
P2-259 Cancer risk in children with birth defects
Introduction The published literature, to date, is largely inconclusive regarding cancer risk among children with birth defects. To improve knowledge of such risk, we studied population-based (statewide) birth cohorts from Arizona, Iowa, and Utah selected from among 2.7 million births delivered from 1983 to 2006. Methods Birth defect and cancer diagnoses were identified from linked population-based surveillance systems. A population-based cohort …
Developing a questionnaire to measure the psychosocial impact of an abnormal cervical smear result and its subsequent management
Comparison of diet history interview and self completed questionnaire in assessment of diet in an elderly population
STUDY OBJECTIVE--The aim of the study was to determine the reliability of a diet history interview with a short self completed questionnaire of a basic design used in other studies in the United Kingdom. DESIGN--The study used a cohort of elderly people randomly divided into two groups after stratification for sex. Members of one group completed the questionnaire first and were interviewed later; the procedure was reversed for the other group. SE…
Ptolemais 1978
An abstract is not available for this content so a preview has been provided. Please use the Get access link above for information on how to access this content
Stillbirth in Canada
The archaic definition and registration processes for stillbirth currently prevalent in Canada impede both clinical care and public health. The situation is fraught because of definitional problems related to the inclusion of induced abortions at ≥20 weeks’ gestation as stillbirths: widespread uptake of prenatal diagnosis and induced abortion for serious congenital anomalies has resulted in an artefactual temporal increase in stillbirth rates in …
Ptolemais 1978
An abstract is not available for this content so a preview has been provided. Please use the Get access link above for information on how to access this content
Research in epidemiology and community health in the medical curriculum
Medical students in Nottingham all complete an honours Bachelor of Medical Sciences course in one department including a research project. The honours programme in community health is described, with results from a survey of the 122 graduates since the medical school started. The 98 (80%) responses showed high levels of satisfaction and gain from the programme, the great majority regarding the course as valuable, enjoyable, and giving both resear…
Current topics in Aids
Housing and health in West Belfast
Book reviews smokers often inhale considerably more carcinogens than machine measurements would indicate.The book is well presented and illustrated with bar charts and graphs
Comparison of diet history interview and self completed questionnaire in assessment of diet in an elderly population
STUDY OBJECTIVE--The aim of the study was to determine the reliability of a diet history interview with a short self completed questionnaire of a basic design used in other studies in the United Kingdom. DESIGN--The study used a cohort of elderly people randomly divided into two groups after stratification for sex. Members of one group completed the questionnaire first and were interviewed later; the procedure was reversed for the other group. SE…
Developing a questionnaire to measure the psychosocial impact of an abnormal cervical smear result and its subsequent management
P2-259 Cancer risk in children with birth defects
Introduction The published literature, to date, is largely inconclusive regarding cancer risk among children with birth defects. To improve knowledge of such risk, we studied population-based (statewide) birth cohorts from Arizona, Iowa, and Utah selected from among 2.7 million births delivered from 1983 to 2006. Methods Birth defect and cancer diagnoses were identified from linked population-based surveillance systems. A population-based cohort …
A Qualitative Study of Provider Perspectives of Structural Barriers to Cervical Cancer Screening Among First Nations Women
Strategies for Increasing Cervical Cancer Screening Amongst First Nations Communities in Northwest Ontario, Canada
The high burden of cervical cancer in Indigenous populations worldwide is due to underscreening and inadequate follow-up. Using qualitative, participatory action research, we interviewed health care staff to identify ways to increase screening recruitment in First Nations communities in Northwest Ontario, Canada. Our findings suggest the value of a multilevel social-ecological model to promote behavioral changes at the community, health care serv…
A vision for chronic disease prevention and intervention research
Expectations and values about expanded newborn screening
OBJECTIVES: Newborn bloodspot screening (NBS) panels have expanded to include conditions for which treatment effects are less certain, creating debate about population-based screening criteria. We investigated Canadian public expectations and values regarding the types of conditions that should be included in NBS and whether parents should provide consent. METHODS: Eight focus groups (FG; n = 60) included education, deliberative discussion and pr…
Long-Term Worries after Colposcopy
They Should Be Asking Us”
In this study, we examine from multiple perspectives, women's shared decision-making needs when considering cervical screening options: Pap testing, in-clinic human papillomavirus (HPV) testing, self-collected HPV testing, or no screening. The Ottawa Decision Support Framework guided the development of the interview schedule. We conducted semi-structured interviews with seven screen-eligible women and five health care professionals (three health …
Improving Social Justice in Covid-19 Health Research
The COVID-19 pandemic has highlighted the global imperative to address health inequities. Observational studies are a valuable source of evidence for real-world effects and impacts of implementing COVID-19 policies on the redistribution of inequities. We assembled a diverse global multi-disciplinary team to develop interim guidance for improving transparency in reporting health equity in COVID-19 observational studies. We identified 14 areas in t…
Stillbirth in Canada
The archaic definition and registration processes for stillbirth currently prevalent in Canada impede both clinical care and public health. The situation is fraught because of definitional problems related to the inclusion of induced abortions at ≥20 weeks’ gestation as stillbirths: widespread uptake of prenatal diagnosis and induced abortion for serious congenital anomalies has resulted in an artefactual temporal increase in stillbirth rates in …
Examining the Implementation of the Performance-Based Financing Equity Strategy in Improving Access and Utilization of Maternal Health Services in Cameroon
Performance-based financing (PBF)-a supply-side strategy that incentivizes health providers based on predefined quality and quantity criteria-introduced an innovative approach to reaching the poor by means of using PBF equity instruments. These PBF equity instruments include paying providers more to reach out to poor women, selecting services used by the poor, subsidizing user fees to reduce out-of-pocket expenses, and adding complementary demand…
A systematic review of the effect of performance-based financing interventions on out-of-pocket expenses to improve access to, and the utilization of, maternal health services across health sectors in…
Improving social justice in observational studies
Achieving global imperatives such as the Sustainable Development Goals (e.g., SDG 10 Reduced inequalities, SDG 3 Good health and wellbeing) requires advancing health equity in research. The implementation of the STROBE-Equity guidelines will enable a better awareness and understanding of health inequities through better reporting. We will broadly disseminate the reporting guideline with tools to enable adoption and use by journal editors, authors…
Clinical and serological predictors of post Covid-19 condition–findings from a Canadian prospective cohort study
Introduction More than 3 years into the pandemic, there is persisting uncertainty as to the etiology, biomarkers, and risk factors of Post COVID-19 Condition (PCC). Serological research data remain a largely untapped resource. Few studies have investigated the potential relationships between post-acute serology and PCC, while accounting for clinical covariates. Methods We compared clinical and serological predictors among COVID-19 survivors with …
Reporting of equity in observational epidemiology
Background: Observational studies can inform how we understand and address persisting health inequities through the collection, reporting and analysis of health equity factors. However, the extent to which the analysis and reporting of equity-relevant aspects in observational research are generally unknown. Thus, we aimed to systematically evaluate how equity-relevant observational studies reported equity considerations in the study design and an…
Folate and global health
Folate and global health review series, part 4
Background: Autoimmune diseases and bone density loss (osteopenia and osteoporosis) are chronic conditions of complex aetiology that affect diverse populations. Folate may be associated with a higher risk of these disorders due to its essential role in one-carbon metabolism required for nucleotide synthesis, homocysteine metabolism, and methylation processes. However, the evidence on this association is inconclusive. Methods: We searched MEDLINE,…
Evaluating the perceived outcome and impact of an integrated knowledge translation approach in the development of an equity reporting guideline
Integrated knowledge translation (IKT) involves active engagement of knowledge users in co-producing research, ensuring their perspectives shape study design, analysis, and reporting. This can strengthen justice, equity, diversity, and inclusion (JEDI) considerations. We adopted an IKT approach in developing STROBE-Equity, an equity-focused reporting guidelin extension. The perceived value of embedding JEDI principles in reporting guideline devel…
Folate and global health umbrella review series, part 1
Background: Folate is essential for normal growth and in human health throughout the lifecycle. Clinical deficiency of folate impairs DNA synthesis and results in megaloblastic anaemia, while suboptimal folate status before and in early pregnancy results in an elevated risk of neural tube defects (NTD). The evidence on the association of folate status with other health outcomes is largely fragmented and understudied. We conducted a series of umbr…
Folate and global health review series, part 3
Background: Cardiovascular and metabolic diseases account for an increasing share of morbidity and mortality globally. Folic acid supplementation has been linked to a lowered risk of stroke and some metabolic indicators due to its involvement in homocysteine and one-carbon metabolism and its role in the production of nitric oxide; however, the evidence on these associations is inconclusive. Methods: We searched MEDLINE, Embase, CINAHL, the Cochra…
Medicine (18 obras) · Environmental health (9 obras) · MEDLINE (7 obras) · Political science (7 obras) · Public health (7 obras) · Cancer (6 obras) · Family medicine (6 obras) · Folate and B Vitamins Research (6 obras) · Internal Medicine (6 obras) · Nursing (6 obras)