Malcolm Maclure
Datos Biográficos
| ID | 5534762 |
|---|---|
| NOMBRE | Malcolm Maclure |
| NOMBRES | Malcolm |
| APELLIDO | Maclure |
| FIRMA | MACLURE M |
| AFILIACIONES | Harvard University |
| ORCID | 0000-0002-3655-6495 |
| VERIFICADO | Sí |
| TOTAL DE OBRAS | 10 |
| TOTAL DE CITAS | 11 |
| TOTAL COMO AUTOR | 10 |
| TOTAL COMO EDITOR | 0 |
| PRIMER AÑO DE PUBLICACIÓN | 1989 |
| AÑO MÁS RECIENTE DE PUBLICACIÓN | 2009 |
| ÍNDICE H | 2 |
Effects of Prescription Coinsurance and Income-Based Deductibles on Net Health Plan Spending for Older Users of Inhaled Medications
BACKGROUND: Health plans that increase prescription cost-sharing for their patients may increase overall plan costs. We analyzed the impact on health plan spending of a switch in public drug insurance from full coverage to a prescription copayment (copay), and then to income-based deductibles plus coinsurance (IBD). METHODS: We studied British Columbia residents 65 years of age or older who were dispensed inhaled steroids, beta2 agonists or antic…
Designed Delays Versus Rigorous Pragmatic Trials
BACKGROUND: Centralized administrative databases enable low-cost pragmatic randomized trials (PRTs) of drug effectiveness and safety. We simplified the PRT strategy by using designed delays (DD) to evaluate drug policies. OBJECTIVES: To reassess our DD trial of a cost-saving nebulizer-to-inhaler conversion policy and a proposed DD trial of reduced restrictions on Cox-2 inhibitors. RESEARCH DESIGN: We randomized 52 pairs of communities and cluster…
Increasing Levels of Restriction in Pharmacoepidemiologic Database Studies of Elderly and Comparison With Randomized Trial Results
BACKGROUND: The goal of restricting study populations is to make patients more homogeneous regarding potential confounding factors and treatment effects and thereby achieve less biased effect estimates. OBJECTIVES: This article describes increasing levels of restrictions for use in pharmacoepidemiology and examines to what extent they change rate ratio estimates and reduce bias in a study of statin treatment and 1-year mortality. METHODS: : The s…
Net Health Plan Savings From Reference Pricing for Angiotensin-Converting Enzyme Inhibitors in Elderly British Columbia Residents
BACKGROUND: Reference drug pricing (RP) is a cost-sharing strategy commonly used to control drug expenditures. Under RP, a benefit plan fully reimburses medications that are equally or less expensive than the reference price, and requires patients to pay the extra cost of therapeutically equivalent but higher priced drugs. Critics argued that drug plan savings are offset by administrative costs and increased spending on other health services. OBJ…
What Is Direct Evidence-Based Policy-Making? Experience from the Drug Benefits Program for Seniors in British Columbia
Malcolm Maclure, Tanya M. Potashnik, What Is Direct Evidence-Based Policy-Making? Experience from the Drug Benefits Program for Seniors in British Columbia, Canadian Public Policy / Analyse de Politiques, Vol. 23, Special Joint Issue: Aging / Vieillissement (Spring, 1997), pp. 132-146
Seniors' Views of Medication Reimbursement Policies
Neena L. Chappell, Malcolm Maclure, Howard Brunt, Jennifer Hopkinson, Jennifer Mullett, Seniors' Views of Medication Reimbursement Policies: Bridging Research and Policy at the Point of Policy Impact, Canadian Public Policy / Analyse de Politiques, Vol. 23, Special Joint Issue: Aging / Vieillissement (Spring, 1997), pp. 114-131
The Case-Crossover Design
A case-control design involving only cases may be used when brief exposure causes a transient change in risk of a rare acute-onset disease. The design resembles a retrospective nonrandomized crossover study but differs in having only a sample of the base population-time. The average incidence rate ratio for a hypothesized effect period following the exposure is estimable using the Mantel-Haenszel estimator. The duration of the effect period is as…
Letters on Epidemiologic Research Methods
Letters on Epidemiologic Research Methods II. Inconsistent with Time-tested Epidemiologic Methods Malcolm Maclure CopyRight https://doi.org/10.2105/AJPH.80.5.623 Published Online: October 07, 2011
Response from Malcolm Maclure, et al
Response from Malcolm Maclure, et al Malcolm Maclure, Ronit B-A. Katz, Matthew S. Bryant, Paul L. Skipper, and Steven R. Tannenbaum CopyRight https://doi.org/10.2105/AJPH.80.8.1002-b Published Online: October 07, 2011
Elevated blood levels of carcinogens in passive smokers
The hypothesis that involuntary exposure to tobacco smoke--passive smoking--results in greater risk of cancer was assessed by measuring the levels of two known carcinogens in the blood of 57 nonsmokers with varying degrees of involuntary exposure, including six heavily exposed bartenders. The concentrations of hemoglobin adducts of 4-aminobiphenyl, a bladder carcinogen, were significantly higher in subjects with confirmed involuntary exposure (pl…
Elevated blood levels of carcinogens in passive smokers
The hypothesis that involuntary exposure to tobacco smoke--passive smoking--results in greater risk of cancer was assessed by measuring the levels of two known carcinogens in the blood of 57 nonsmokers with varying degrees of involuntary exposure, including six heavily exposed bartenders. The concentrations of hemoglobin adducts of 4-aminobiphenyl, a bladder carcinogen, were significantly higher in subjects with confirmed involuntary exposure (pl…
What Is Direct Evidence-Based Policy-Making? Experience from the Drug Benefits Program for Seniors in British Columbia
Malcolm Maclure, Tanya M. Potashnik, What Is Direct Evidence-Based Policy-Making? Experience from the Drug Benefits Program for Seniors in British Columbia, Canadian Public Policy / Analyse de Politiques, Vol. 23, Special Joint Issue: Aging / Vieillissement (Spring, 1997), pp. 132-146
Seniors' Views of Medication Reimbursement Policies
Neena L. Chappell, Malcolm Maclure, Howard Brunt, Jennifer Hopkinson, Jennifer Mullett, Seniors' Views of Medication Reimbursement Policies: Bridging Research and Policy at the Point of Policy Impact, Canadian Public Policy / Analyse de Politiques, Vol. 23, Special Joint Issue: Aging / Vieillissement (Spring, 1997), pp. 114-131
Elevated blood levels of carcinogens in passive smokers
The hypothesis that involuntary exposure to tobacco smoke--passive smoking--results in greater risk of cancer was assessed by measuring the levels of two known carcinogens in the blood of 57 nonsmokers with varying degrees of involuntary exposure, including six heavily exposed bartenders. The concentrations of hemoglobin adducts of 4-aminobiphenyl, a bladder carcinogen, were significantly higher in subjects with confirmed involuntary exposure (pl…
Letters on Epidemiologic Research Methods
Letters on Epidemiologic Research Methods II. Inconsistent with Time-tested Epidemiologic Methods Malcolm Maclure CopyRight https://doi.org/10.2105/AJPH.80.5.623 Published Online: October 07, 2011
Response from Malcolm Maclure, et al
Response from Malcolm Maclure, et al Malcolm Maclure, Ronit B-A. Katz, Matthew S. Bryant, Paul L. Skipper, and Steven R. Tannenbaum CopyRight https://doi.org/10.2105/AJPH.80.8.1002-b Published Online: October 07, 2011
The Case-Crossover Design
A case-control design involving only cases may be used when brief exposure causes a transient change in risk of a rare acute-onset disease. The design resembles a retrospective nonrandomized crossover study but differs in having only a sample of the base population-time. The average incidence rate ratio for a hypothesized effect period following the exposure is estimable using the Mantel-Haenszel estimator. The duration of the effect period is as…
What Is Direct Evidence-Based Policy-Making? Experience from the Drug Benefits Program for Seniors in British Columbia
Malcolm Maclure, Tanya M. Potashnik, What Is Direct Evidence-Based Policy-Making? Experience from the Drug Benefits Program for Seniors in British Columbia, Canadian Public Policy / Analyse de Politiques, Vol. 23, Special Joint Issue: Aging / Vieillissement (Spring, 1997), pp. 132-146
Seniors' Views of Medication Reimbursement Policies
Neena L. Chappell, Malcolm Maclure, Howard Brunt, Jennifer Hopkinson, Jennifer Mullett, Seniors' Views of Medication Reimbursement Policies: Bridging Research and Policy at the Point of Policy Impact, Canadian Public Policy / Analyse de Politiques, Vol. 23, Special Joint Issue: Aging / Vieillissement (Spring, 1997), pp. 114-131
Net Health Plan Savings From Reference Pricing for Angiotensin-Converting Enzyme Inhibitors in Elderly British Columbia Residents
BACKGROUND: Reference drug pricing (RP) is a cost-sharing strategy commonly used to control drug expenditures. Under RP, a benefit plan fully reimburses medications that are equally or less expensive than the reference price, and requires patients to pay the extra cost of therapeutically equivalent but higher priced drugs. Critics argued that drug plan savings are offset by administrative costs and increased spending on other health services. OBJ…
Designed Delays Versus Rigorous Pragmatic Trials
BACKGROUND: Centralized administrative databases enable low-cost pragmatic randomized trials (PRTs) of drug effectiveness and safety. We simplified the PRT strategy by using designed delays (DD) to evaluate drug policies. OBJECTIVES: To reassess our DD trial of a cost-saving nebulizer-to-inhaler conversion policy and a proposed DD trial of reduced restrictions on Cox-2 inhibitors. RESEARCH DESIGN: We randomized 52 pairs of communities and cluster…
Increasing Levels of Restriction in Pharmacoepidemiologic Database Studies of Elderly and Comparison With Randomized Trial Results
BACKGROUND: The goal of restricting study populations is to make patients more homogeneous regarding potential confounding factors and treatment effects and thereby achieve less biased effect estimates. OBJECTIVES: This article describes increasing levels of restrictions for use in pharmacoepidemiology and examines to what extent they change rate ratio estimates and reduce bias in a study of statin treatment and 1-year mortality. METHODS: : The s…
Effects of Prescription Coinsurance and Income-Based Deductibles on Net Health Plan Spending for Older Users of Inhaled Medications
BACKGROUND: Health plans that increase prescription cost-sharing for their patients may increase overall plan costs. We analyzed the impact on health plan spending of a switch in public drug insurance from full coverage to a prescription copayment (copay), and then to income-based deductibles plus coinsurance (IBD). METHODS: We studied British Columbia residents 65 years of age or older who were dispensed inhaled steroids, beta2 agonists or antic…
Medicine (8 obras) · Environmental health (5 obras) · Health Systems, Economic Evaluations, Quality of Life (5 obras) · Medication Adherence and Compliance (4 obras) · Advanced Causal Inference Techniques (3 obras) · Business (3 obras) · Confidence interval (3 obras) · Internal Medicine (3 obras) · Actuarial science (2 obras) · Computer Science (2 obras)