Abhinav Sinha
Datos Biográficos
| ID | 6173183 |
|---|---|
| NOMBRE | Abhinav Sinha |
| NOMBRES | Abhinav |
| APELLIDO | Sinha |
| FIRMA | SINHA A |
| AFILIACIONES | Regional Medical Research Centre |
| ORCID | 0000-0001-7702-3671 |
| VERIFICADO | Sí |
| TOTAL DE OBRAS | 30 |
| TOTAL DE CITAS | 0 |
| TOTAL COMO AUTOR | 19 |
| TOTAL COMO EDITOR | 11 |
| PRIMER AÑO DE PUBLICACIÓN | 2008 |
| AÑO MÁS RECIENTE DE PUBLICACIÓN | 2026 |
| ÍNDICE H | 0 |
Elevated ANG2/ACE2 and immune responses associated with Plasmodium falciparum and Sars-CoV-2 coinfection in Cameroon
Malaria and COVID-19 co-infections pose a major clinical challenge, as overlapping symptoms can lead to misdiagnosis and delays in treatment. Emerging evidence suggests that SARS-CoV-2 may influence malaria pathogenesis through dysregulation of the renin–angiotensin system. This study assessed clinical, biochemical, and immunological alterations associated with single and dual infections. A total of 96 participants aged 15–64 years were enrolled …
Health-related quality of life among multimorbid patients using the EQ-5D-5L value set for India
Multimorbidity presents major challenges to healthcare systems worldwide. Assessing health-related quality-of-life (HRQoL) in multimorbid patients is essential for understanding the overall impact of the patient’s health conditions on wellbeing and the complexities of patient management. This study assessed the HRQoL of multimorbid patients in India using the EQ-5D-5L value set. This observational study included 906 patients from tertiary healthc…
Sex and gender differentials in the prevalence of obesity and its association with multimorbidity among reproductive-aged individuals in India
Introduction The increase in the prevalence of obesity has become a common public health issue worldwide, with low- and middle-income countries (LMICs) like India witnessing an equal rise. It makes a considerable contribution to chronic diseases as it is a major risk factor for other chronic illnesses. Multimorbidity, or the presence of two or more chronic illnesses, is becoming more common in LMICs, resulting in poor health outcomes. However, re…
Prevalence and patterns of multimorbidity among mining workers of Odisha, India
Introduction: Multimorbidity is an emerging public health challenge in India due to rapid industrialization, urbanization and an aging population. Multimorbidity often impacts occupational outcomes, including work-related stress, job loss, absenteeism, and reduced years of service. Odisha, an eastern state of India, is a major mining state with a large workforce exposed to occupational physical and mental stress, and toxic waste. We determined pr…
Time to address the drawbacks in estimation and reporting of malaria cases in India and beyond
India is committed to eliminate malaria by 2030. However, there has been a continuous debate between National Malaria Control Programmes (NMCPs) and World Health rganization (WHO) on the differential perception of malaria burden. The evident gap between the reported cases by NMCPs and WHO estimations, particularly for India, has never been unbiasedly addressed. This work provides a critical understanding of gaps between estimated and reported cas…
Targeted distribution of long-lasting insecticidal nets by community health workers to sustain household coverage
Universal coverage is defined by the World Health Organization as 1 long-lasting insecticidal net (LLIN) for 2 people in a household. While Uganda has been a leader in the distribution of LLINs, there are concerns regarding the longevity of LLINs. The main aim of this study was to address the LLIN coverage gap that emerges in the period after mass distribution campaigns through the implementation of a novel LLIN distribution strategy utilizing th…
Prevalence and patterns of multiple long-term conditions among lymphatic filariasis patients in Odisha, India
We observed a high prevalence of MLTC among people with lymphatic filariasis. The findings of this study will not only be useful for both resource and planning in India but also in similar LMICs with a high burden of lymphatic filariasis
Developing and assessing the “MultiLife” intervention
CTRI.nic.in, CTRI/2024/10/074559, Registered on 1 October 2024
Understanding the association of disability with multimorbidity, and healthcare utilization in India’s older adult population
Background Like other low-and middle-income countries, India is undergoing a demographic and epidemiologic shift that has led to a significant rise in the burden of non-communicable diseases (NCDs). Evidence suggests that chronic illnesses and disability are linked but limited studies have explored the association between disability and multimorbidity (simultaneous presence of two or more chronic conditions). Since the magnitude of multimorbidity…
Implementation of Glucose-6-Phosphate Dehydrogenase (G6PD) testing for Plasmodium vivax case management, a mixed method study from Cambodia
Plasmodium vivax remains a challenge for malaria elimination since it forms dormant liver stages (hypnozoites) that can reactivate after initial infection. 8-aminoquinolone drugs kill hypnozoites but can cause severe hemolysis in individuals with Glucose-6-Phosphate Dehydrogenase (G6PD) deficiency. The STANDARD G6PD test (Biosensor) is a novel point-of-care diagnostic capable of identifying G6PD deficiency prior to treatment. In 2021, Cambodia im…
Characterizing mobility patterns and malaria risk factors in semi-nomadic populations of Northern Kenya
While many studies have characterized mobility patterns and disease dynamics of settled populations, few have focused on more mobile populations. Highly mobile groups are often at higher disease risk due to their regular movement that may increase the variability of their environments, reduce their access to health care, and limit the number of intervention strategies suitable for their lifestyles. Quantifying the movements and their associated d…
Factors associated with the use of long-lasting insecticidal nets in pregnant women and mothers with children under five years of age in Gaza province, Mozambique
Malaria remains a major public health concern worldwide. Malaria is endemic in Mozambique, with seasonal fluctuations throughout the country. Although the number of malaria cases in Mozambique have dropped by 11% from 2020 to 2021, there are still hotspots in the country with persistent high incidence and low insecticide-treated bed net usage. The aim of this study is to evaluate the factors associated with the use of long-lasting insecticidal ne…
Expanding the roles of malaria post workers in Thailand
In Thailand, since the 2000s, malaria post (MP) workers have been tasked with promptly detecting and treating all malaria cases to prevent onward transmission in the communities. Expanding their roles to provide health services beyond malaria has been proposed as a strategy to sustain their activities until elimination is reached. This article examines the perspectives of stakeholders on community-based malaria care to assess prospects for expand…
Seasonal variations in respiratory morbidity in primary care and its correlation with the quality of air in urban Odisha, India
Poor air quality, especially in urban regions among low-and middle-income countries such as India poses a significant healthcare challenge. Amongst urban areas, metropolitan cities garner the utmost importance for air quality related policies and studies with limited studies from tier II cities which are thought to be relatively immune to air pollution. Hence, we aimed to identify the most frequent respiratory morbidities and explore its correlat…
Landscaping tuberculosis multimorbidity
Our findings suggest high prevalence of multimorbidity among newly diagnosed TB patients in India. The presence of concordant and discordant conditions with TB may increase the health complexity, thus necessitating appropriate care protocols. Given, the current situation, wherein TB and non-communicable diseases (NCD) services are delivered through collaborative framework between programmes, there is a need for addressing multimorbidity at the he…
Non-communicable disease multimorbidity among tribal older adults in India
Introduction: Multimorbidity defined as the simultaneous presence of two or more chronic conditions in an individual is on the rise in low- and middle-income countries such as India. With India aiming to achieve universal health coverage, it is imperative to address the inequalities in accessing healthcare, especially among vulnerable groups such as tribal. Moreover, changing lifestyle has led to the emergence of multimorbidity among tribals in I…
Smokeless tobacco utilization among tribal communities in India
Introduction: Evidence on smokeless tobacco use is scarce among indigenous communities, with the available literature based either on a specific tribe or on a particular region. Therefore, we aimed to estimate the prevalence of smokeless tobacco and assess its correlation among tribal communities in India. Methods: We utilized data from the Global Adult Tobacco Survey-2 conducted in 2016-2017. A total of 12,854 tribal people aged >15 years were i…
Adherence to malaria treatment guidelines among health care workers in private health facilities in Kampala’s informal settlements, Uganda
Poor adherence to malaria treatment guidelines among healthcare workers (HCWs) is a major contribution to diagnostic challenges, treatment failure, and non-rational use of antimalarial medicines. However, there is limited information about adherence to malaria treatment guidelines among HCWs in private health facilities in informal settlements in Uganda. This study therefore assessed the level of adherence to malaria treatment guidelines and asso…
Altitude, not potential larval habitat availability, explains pronounced variation in Plasmodium falciparum infection prevalence in the western Kenya highlands
Progress in malaria control has stalled over the recent years. Knowledge on main drivers of transmission explaining small-scale variation in prevalence can inform targeted control measures. We collected finger-prick blood samples from 3061 individuals irrespective of clinical symptoms in 20 clusters in Busia in western Kenya and screened for Plasmodium falciparum parasites using qPCR and microscopy. Clusters spanned an altitude range of 207 meter…
Childhood health and educational disadvantage are associated with adult multimorbidity in the global south
INTRODUCTION: Multimorbidity has emerged as a major healthcare challenge in low/middle-income countries (LMICs) such as India and Brazil. Life course epidemiology suggests that adverse events in early life contribute to an individual's later health in adulthood. However, little is known about the influence of early life health and social factors on the development of multimorbidity in adulthood in LMICs. We aimed to explore the association of adu…
Multimorbidity Among Urban Poor in India
Background: Multimorbidity has become a norm in low-and middle-income countries such as India requiring notable health system improvements to combat. Urban population is a heterogeneous group where poor are at a risk of facing inequity in accessing healthcare services which can jeopardize our efforts to attain universal health coverage (UHC). We aimed to estimate the prevalence, assess correlates and patterns of multimorbidity among urban poor. F…
“Testing for malaria does not cure any pain” A qualitative study exploring low use of malaria rapid diagnostic tests at drug shops in rural Uganda
The World Health Organization recommends all suspected malaria cases be confirmed with a parasitological test, typically a rapid diagnostic test (RDT), prior to treatment. Despite recommendations, many fevers presenting at private drug shops are treated presumptively as malaria without diagnostic testing. The purpose of this qualitative study was to describe community perceptions of RDTs and explore ways to improve malaria case management at drug…
QPCR in a suitcase for rapid Plasmodium falciparum and Plasmodium vivax surveillance in Ethiopia
Many Plasmodium spp. infections, both in clinical and asymptomatic patients, are below the limit of detection of light microscopy or rapid diagnostic test (RDT). Molecular diagnosis by qPCR can be valuable for surveillance, but is often hampered by absence of laboratory capacity in endemic countries. To overcome this limitation, we optimized and tested a mobile qPCR laboratory for molecular diagnosis in Ziway, Ethiopia, where transmission intensi…
Family-Level Multimorbidity among Older Adults in India
Most evidence on multimorbidity is drawn from an individual level assessment despite the fact that multimorbidity is modulated by shared risk factors prevailing within the household environment. Our study reports the magnitude of family-level multimorbidity, its correlates, and healthcare expenditure among older adults using data from the Longitudinal Ageing Study in India (LASI), wave-1. LASI is a nationwide survey amongst older adults aged ≥45 …
Multimorbidity and Complex Multimorbidity in India
Complex multimorbidity refers to the co-occurrence of three or more chronic illnesses across >2 body systems, which may identify persons in need of additional medical support and treatment. There is a scarcity of evidence on the differences in patient outcomes between non-complex (≥2 conditions) and complex multimorbidity groups. We evaluated the prevalence and patient outcomes of complex multimorbidity and compared them to non-complex multimorbi…
Sin obras prominentes en esta página.
Knowledge, attitude and practice of disaster preparedness and mitigation among medical students
Purpose The purpose of this paper is to assess the present level of knowledge about disaster preparedness and mitigation among undergraduate medical students. Rarely a week goes by when a major disaster is not reported in the media – a disaster that results in death and destruction. There is a general reluctance among the people to accept that tragedy can appear any time in the form of a disaster. Unfortunately, disasters are seen more in context…
Field evaluation of specificity and sensitivity of a standard Sars-CoV-2 antigen rapid diagnostic test
The testing capacity for SARS-CoV-2 in Africa is rather limited. Antigen detection rapid diagnostic tests (Ag-RDTs) are a cheap and rapid alternative to reverse transcriptase-polymerase chain reaction (RT-PCR) tests, but there is little data about their performance under real life conditions in tropical countries. The objective of this study is to evaluate the performance of a standard Ag-RDT in a population of a major hospital in northern Ghana.…
Association of Oral Health with Multimorbidity among Older Adults
India is witnessing an increase in the prevalence of multimorbidity. Oral health is related to overall health but is seldom included in the assessment of multimorbidity. Hence, this study aimed to estimate the prevalence of oral morbidity and explore its association with physical multimorbidity using data from Longitudinal Ageing Study in India (LASI). LASI is a nationwide survey amongst adults aged ≥ 45 years conducted in 2018. Descriptive analy…
Declining trends in smokeless tobacco use among Indian women
Although, smokeless tobacco prevalence among females has reduced between 2009 and 2016 in India, yet tobacco control strategies need further pace. Hence, more focused gender-based tobacco control programs and policies are the need of time
On the Question of Methodology in Labour History
The present paper deals with some basic questions of methodology in labour history. It deals with three main questions: the question of class and social identities in labour history; the question of the category of ‘labouring poor’ vis-à-vis the category of working class; and finally, the question of the place of state in treating the relation between labour and capital. On the first question, it argues that social identities become sites of soci…
Multimorbidity Among Urban Poor in India
Background: Multimorbidity has become a norm in low-and middle-income countries such as India requiring notable health system improvements to combat. Urban population is a heterogeneous group where poor are at a risk of facing inequity in accessing healthcare services which can jeopardize our efforts to attain universal health coverage (UHC). We aimed to estimate the prevalence, assess correlates and patterns of multimorbidity among urban poor. F…
“Testing for malaria does not cure any pain” A qualitative study exploring low use of malaria rapid diagnostic tests at drug shops in rural Uganda
The World Health Organization recommends all suspected malaria cases be confirmed with a parasitological test, typically a rapid diagnostic test (RDT), prior to treatment. Despite recommendations, many fevers presenting at private drug shops are treated presumptively as malaria without diagnostic testing. The purpose of this qualitative study was to describe community perceptions of RDTs and explore ways to improve malaria case management at drug…
QPCR in a suitcase for rapid Plasmodium falciparum and Plasmodium vivax surveillance in Ethiopia
Many Plasmodium spp. infections, both in clinical and asymptomatic patients, are below the limit of detection of light microscopy or rapid diagnostic test (RDT). Molecular diagnosis by qPCR can be valuable for surveillance, but is often hampered by absence of laboratory capacity in endemic countries. To overcome this limitation, we optimized and tested a mobile qPCR laboratory for molecular diagnosis in Ziway, Ethiopia, where transmission intensi…
Family-Level Multimorbidity among Older Adults in India
Most evidence on multimorbidity is drawn from an individual level assessment despite the fact that multimorbidity is modulated by shared risk factors prevailing within the household environment. Our study reports the magnitude of family-level multimorbidity, its correlates, and healthcare expenditure among older adults using data from the Longitudinal Ageing Study in India (LASI), wave-1. LASI is a nationwide survey amongst older adults aged ≥45 …
Multimorbidity and Complex Multimorbidity in India
Complex multimorbidity refers to the co-occurrence of three or more chronic illnesses across >2 body systems, which may identify persons in need of additional medical support and treatment. There is a scarcity of evidence on the differences in patient outcomes between non-complex (≥2 conditions) and complex multimorbidity groups. We evaluated the prevalence and patient outcomes of complex multimorbidity and compared them to non-complex multimorbi…
Non-communicable disease multimorbidity among tribal older adults in India
Introduction: Multimorbidity defined as the simultaneous presence of two or more chronic conditions in an individual is on the rise in low- and middle-income countries such as India. With India aiming to achieve universal health coverage, it is imperative to address the inequalities in accessing healthcare, especially among vulnerable groups such as tribal. Moreover, changing lifestyle has led to the emergence of multimorbidity among tribals in I…
Smokeless tobacco utilization among tribal communities in India
Introduction: Evidence on smokeless tobacco use is scarce among indigenous communities, with the available literature based either on a specific tribe or on a particular region. Therefore, we aimed to estimate the prevalence of smokeless tobacco and assess its correlation among tribal communities in India. Methods: We utilized data from the Global Adult Tobacco Survey-2 conducted in 2016-2017. A total of 12,854 tribal people aged >15 years were i…
Adherence to malaria treatment guidelines among health care workers in private health facilities in Kampala’s informal settlements, Uganda
Poor adherence to malaria treatment guidelines among healthcare workers (HCWs) is a major contribution to diagnostic challenges, treatment failure, and non-rational use of antimalarial medicines. However, there is limited information about adherence to malaria treatment guidelines among HCWs in private health facilities in informal settlements in Uganda. This study therefore assessed the level of adherence to malaria treatment guidelines and asso…
Altitude, not potential larval habitat availability, explains pronounced variation in Plasmodium falciparum infection prevalence in the western Kenya highlands
Progress in malaria control has stalled over the recent years. Knowledge on main drivers of transmission explaining small-scale variation in prevalence can inform targeted control measures. We collected finger-prick blood samples from 3061 individuals irrespective of clinical symptoms in 20 clusters in Busia in western Kenya and screened for Plasmodium falciparum parasites using qPCR and microscopy. Clusters spanned an altitude range of 207 meter…
Childhood health and educational disadvantage are associated with adult multimorbidity in the global south
INTRODUCTION: Multimorbidity has emerged as a major healthcare challenge in low/middle-income countries (LMICs) such as India and Brazil. Life course epidemiology suggests that adverse events in early life contribute to an individual's later health in adulthood. However, little is known about the influence of early life health and social factors on the development of multimorbidity in adulthood in LMICs. We aimed to explore the association of adu…
Understanding the association of disability with multimorbidity, and healthcare utilization in India’s older adult population
Background Like other low-and middle-income countries, India is undergoing a demographic and epidemiologic shift that has led to a significant rise in the burden of non-communicable diseases (NCDs). Evidence suggests that chronic illnesses and disability are linked but limited studies have explored the association between disability and multimorbidity (simultaneous presence of two or more chronic conditions). Since the magnitude of multimorbidity…
Implementation of Glucose-6-Phosphate Dehydrogenase (G6PD) testing for Plasmodium vivax case management, a mixed method study from Cambodia
Plasmodium vivax remains a challenge for malaria elimination since it forms dormant liver stages (hypnozoites) that can reactivate after initial infection. 8-aminoquinolone drugs kill hypnozoites but can cause severe hemolysis in individuals with Glucose-6-Phosphate Dehydrogenase (G6PD) deficiency. The STANDARD G6PD test (Biosensor) is a novel point-of-care diagnostic capable of identifying G6PD deficiency prior to treatment. In 2021, Cambodia im…
Characterizing mobility patterns and malaria risk factors in semi-nomadic populations of Northern Kenya
While many studies have characterized mobility patterns and disease dynamics of settled populations, few have focused on more mobile populations. Highly mobile groups are often at higher disease risk due to their regular movement that may increase the variability of their environments, reduce their access to health care, and limit the number of intervention strategies suitable for their lifestyles. Quantifying the movements and their associated d…
Factors associated with the use of long-lasting insecticidal nets in pregnant women and mothers with children under five years of age in Gaza province, Mozambique
Malaria remains a major public health concern worldwide. Malaria is endemic in Mozambique, with seasonal fluctuations throughout the country. Although the number of malaria cases in Mozambique have dropped by 11% from 2020 to 2021, there are still hotspots in the country with persistent high incidence and low insecticide-treated bed net usage. The aim of this study is to evaluate the factors associated with the use of long-lasting insecticidal ne…
Expanding the roles of malaria post workers in Thailand
In Thailand, since the 2000s, malaria post (MP) workers have been tasked with promptly detecting and treating all malaria cases to prevent onward transmission in the communities. Expanding their roles to provide health services beyond malaria has been proposed as a strategy to sustain their activities until elimination is reached. This article examines the perspectives of stakeholders on community-based malaria care to assess prospects for expand…
Seasonal variations in respiratory morbidity in primary care and its correlation with the quality of air in urban Odisha, India
Poor air quality, especially in urban regions among low-and middle-income countries such as India poses a significant healthcare challenge. Amongst urban areas, metropolitan cities garner the utmost importance for air quality related policies and studies with limited studies from tier II cities which are thought to be relatively immune to air pollution. Hence, we aimed to identify the most frequent respiratory morbidities and explore its correlat…
Landscaping tuberculosis multimorbidity
Our findings suggest high prevalence of multimorbidity among newly diagnosed TB patients in India. The presence of concordant and discordant conditions with TB may increase the health complexity, thus necessitating appropriate care protocols. Given, the current situation, wherein TB and non-communicable diseases (NCD) services are delivered through collaborative framework between programmes, there is a need for addressing multimorbidity at the he…
Health-related quality of life among multimorbid patients using the EQ-5D-5L value set for India
Multimorbidity presents major challenges to healthcare systems worldwide. Assessing health-related quality-of-life (HRQoL) in multimorbid patients is essential for understanding the overall impact of the patient’s health conditions on wellbeing and the complexities of patient management. This study assessed the HRQoL of multimorbid patients in India using the EQ-5D-5L value set. This observational study included 906 patients from tertiary healthc…
Sex and gender differentials in the prevalence of obesity and its association with multimorbidity among reproductive-aged individuals in India
Introduction The increase in the prevalence of obesity has become a common public health issue worldwide, with low- and middle-income countries (LMICs) like India witnessing an equal rise. It makes a considerable contribution to chronic diseases as it is a major risk factor for other chronic illnesses. Multimorbidity, or the presence of two or more chronic illnesses, is becoming more common in LMICs, resulting in poor health outcomes. However, re…
Prevalence and patterns of multimorbidity among mining workers of Odisha, India
Introduction: Multimorbidity is an emerging public health challenge in India due to rapid industrialization, urbanization and an aging population. Multimorbidity often impacts occupational outcomes, including work-related stress, job loss, absenteeism, and reduced years of service. Odisha, an eastern state of India, is a major mining state with a large workforce exposed to occupational physical and mental stress, and toxic waste. We determined pr…
Medicine (25 obras) · Environmental health (18 obras) · Population (13 obras) · Public health (13 obras) · Chronic Disease Management Strategies (12 obras) · Demography (12 obras) · Multimorbidity (11 obras) · Malaria (10 obras) · Malaria Research and Control (10 obras) · Health care (9 obras)