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Élodie Lebas

Datos Biográficos

ID6370241
NOMBREÉlodie Lebas
NOMBRESÉlodie
APELLIDOLebas
FIRMALEBAS E
AFILIACIONESUniversity of California, San Francisco
ORCID0000-0003-1617-143X
VERIFICADOSí
TOTAL DE OBRAS14
TOTAL DE CITAS0
TOTAL COMO AUTOR14
TOTAL COMO EDITOR0
PRIMER AÑO DE PUBLICACIÓN2021
AÑO MÁS RECIENTE DE PUBLICACIÓN2026
ÍNDICE H0
  • Micro-costing for national-scale azithromycin mass drug administration to improve child survival in Niger

    Open Access•Brittany Peterson, William Nguyen et al.•ARTICLE•PLOS Global Public Health•2026

    As programs for azithromycin mass drug administration (AZ-MDA) to reduce child mortality have begun in some parts of West Africa, it is imperative to understand their financial costs. We combined a micro-costing framework and observations from an implementation-focused sub-study within the AVENIR trials in 80 communities in the Dosso region of Niger to estimate the national health sector financial costs of a scaled-up programmatic approach for az…

  • Integration of azithromycin mass administration to 1–11-month-old children into an existing health platform to reduce child mortality

    Open Access•Fanny Yago-Wienne, Djeinam Touré et al.•ARTICLE•BMJ Global Health•2026

    BACKGROUND: Azithromycin mass drug administration (MDA) to ages 1-59 months can reduce childhood mortality; however, more evidence is needed to support targeting a narrower age range of 1-11 months. This trial assesses the efficacy of azithromycin MDA to 1-11-month-old children in reducing mortality in a real-world setting with integration of vitamin A delivery within the established Child Health Days platform in Burkina Faso. METHODS: Mortalite …

  • Predictors of home- vs . facility-based delivery among women living in rural Niger

    Open Access•Brittany Peterson, Ahmed M Arzika et al.•ARTICLE•Journal of Global Health•2026

    Background: Niger has one of the highest maternal mortality rates, and facility delivery can help prevent these deaths. While distance to health facilities predicts home delivery in other sub-Saharan African settings, few studies have examined this relationship in Niger. Methods: This cross-sectional survey, an ancillary study to the AVENIR trial, included women aged 12-59 years old with a child participating in a sub-trial of AVENIR. Trained wor…

  • Caregiver Screening for Relapse Among Children Recently Recovered From Severe Acute Malnutrition

    Open Access•Mamadou Bountogo, Clarisse Dah et al.•ARTICLE•Maternal and Child Nutrition•2026

    Relapse to acute malnutrition after recovery from severe acute malnutrition (SAM) is common. However, most programmatic resources are devoted to the acute phase of recovery, and fewer interventions are available for children recently discharged from outpatient nutritional programs. We evaluated the feasibility of training caregivers to screen for relapse using mid-upper arm circumference (MUAC) tapes for reducing time to detection of relapse amon…

  • Seasonality of underweight among infants 1–11 months old in Niger

    Open Access•Brittany Peterson, Ahmed M Arzika et al.•ARTICLE•BMJ Global Health•2025

    INTRODUCTION: Malnutrition is a risk factor for child mortality, with around 45% of deaths in children under 5 globally linked to malnutrition. Seasonality of malnutrition has important implications for the timing of child health programme activities, but evidence is mixed on the nature of such patterns. Moreover, the bulk of the existing evidence is focused on wasting and stunting in children 6-59 months, despite increasing evidence that younger…

  • Effect of biannual azithromycin on respiratory pathogens among symptomatic children

    Open Access•Jie Liu, Stephanie A Brennhofer et al.•ARTICLE•BMJ Global Health•2025

    Introduction Biannual (ie, every 6 months) mass drug administration of azithromycin has reduced childhood mortality in Niger, but its effects on specific respiratory pathogens are not fully elucidated. Methods Across 2 years of the Macrolides Oraux pour Réduire les Décès avec un Oeil sur la Résistance (MORDOR) study in Niger, we evaluated 1468 nasopharyngeal swabs from children who presented for care with respiratory symptoms. Swabs were tested b…

  • The role of seasonal malaria chemoprevention in the effect of azithromycin on child mortality

    Open Access•Elisabeth Gebreegziabher, Mamadou Ouattara et al.•ARTICLE•PLOS Global Public Health•2025

    The objective of this study was to examine whether the effect of mass Azithromycin (AZ) distribution on all-cause mortality among children under 5 varies with seasonal malaria chemoprevention (SMC) administration season or coverage. This was a secondary analysis of the Community Health with Azithromycin Trial (CHAT), a cluster-randomized, placebo-controlled trial of twice-yearly AZ treatment in 341 communities in the Nouna District, Burkina Faso.…

  • Mass azithromycin for prevention of child mortality among children with acute malnutrition

    Open Access•Ali Sié, Mamadou Ouattara et al.•ARTICLE•PLOS Global Public Health•2024

    Children with acute malnutrition are at high risk of morality. Mass azithromycin distribution reduces all-cause mortality among children aged 1–59 months, and effects may be greater in underweight infants. Here, we evaluate the efficacy of azithromycin for reducing all-cause mortality in children aged 6–59 months with acute malnutrition (mid-upper arm circumference, MUAC, P -value for interaction on the relative scale = 0.09; P -value for interac…

  • Neonatal anthropometric indicators of infant growth and mortality in Burkina Faso

    Open Access•Mamadou Bountogo, Ali Sié et al.•ARTICLE•Public Health Nutrition•2024

    Objective: Most evidence supporting screening for undernutrition is for children aged 6–59 months. However, the highest risk of mortality and highest incidence of wasting occurs in the first 6 months of life. We evaluated relationships between neonatal anthropometric indicators, including birth weight, weight-for-age Z -score (WAZ), weight-for-length Z-score (WLZ), length-for-age Z -score (LAZ) and mid-upper arm circumference (MUAC) and mortality…

  • Comparison of door-to-door and fixed-point delivery of azithromycin distribution for child survival in Niger

    Open Access•Ahmed M Arzika, Ramatou Maliki et al.•ARTICLE•PLOS Global Public Health•2023

    Recent evidence indicates mass azithromycin distribution reduces under-5 mortality. This intervention is being considered for child survival programs in high mortality sub-Saharan African settings. The delivery approach used in prior studies required a full-time census and distribution team, which is not feasible for most programs. To determine the optimal programmatic approach to delivery, this study aimed to compare treatment coverage, costs, a…

  • Infant mortality and growth failure after oral azithromycin among low birthweight and underweight neonates

    Open Access•Mamadou Bountogo, Ali Sié et al.•ARTICLE•PLOS Global Public Health•2023

    Background Low birthweight (birthweight Methods Infants aged 8–27 days of age weighing ≥2500 g at enrollment in Burkina Faso were randomized 1:1 to a single, oral dose of azithromycin (20 mg/kg) or matching placebo. We evaluated mortality and anthropometric outcomes in four subgroups: 1) both low birthweight and underweight at enrollment; 2) low birthweight-only; 3) underweight-only; 4) neither low birthweight nor underweight. Findings Of 21,832 …

  • Simplified dosing of oral azithromycin for children 1–11 months old in child survival programmes

    Open Access•Huiyu Hu, Ahmed M Arzika et al.•ARTICLE•BMJ Global Health•2022

    BACKGROUND: To facilitate mass distribution of azithromycin, trachoma control programmes use height instead of weight to determine dose for children 6 months to 15 years old. WHO has recommended azithromycin distribution to children 1-11 months old to reduce mortality in high mortality settings under carefully monitored conditions. Weight was used to determine dose in children 1-5 months old in studies of azithromycin distribution for child survi…

  • How does baseline anthropometry affect anthropometric outcomes in children receiving treatment for severe acute malnutrition? A secondary analysis of a randomized controlled trial

    Open Access•Clarisse Dah, Ourohiré Millogo et al.•ARTICLE•Maternal and Child Nutrition•2022

    Mid-upper arm circumference (MUAC) < 11.5 cm and weight-for-height Z-score (WHZ) < -3 are used for screening for severe acute malnutrition (SAM). Underweight and concurrent wasting and stunting may better target those at the highest risk of mortality. We compared anthropometric outcomes in children enrolled in a trial of antibiotics for SAM based on categories of baseline anthropometry, including indicators for programme admission (WHZ < -3, MUAC…

  • Age-based targeting of biannual azithromycin distribution for child survival in Niger

    Open Access•Kieran S O’Brien, Ahmed M Arzika et al.•ARTICLE•BMC Public Health•2021

    This trial was registered on January 13, 2020 (clinicaltrials.gov: NCT04224987 )

Sin obras prominentes en esta página.

  • Age-based targeting of biannual azithromycin distribution for child survival in Niger

    Open Access•Kieran S O’Brien, Ahmed M Arzika et al.•ARTICLE•BMC Public Health•2021

    This trial was registered on January 13, 2020 (clinicaltrials.gov: NCT04224987 )

  • Simplified dosing of oral azithromycin for children 1–11 months old in child survival programmes

    Open Access•Huiyu Hu, Ahmed M Arzika et al.•ARTICLE•BMJ Global Health•2022

    BACKGROUND: To facilitate mass distribution of azithromycin, trachoma control programmes use height instead of weight to determine dose for children 6 months to 15 years old. WHO has recommended azithromycin distribution to children 1-11 months old to reduce mortality in high mortality settings under carefully monitored conditions. Weight was used to determine dose in children 1-5 months old in studies of azithromycin distribution for child survi…

  • How does baseline anthropometry affect anthropometric outcomes in children receiving treatment for severe acute malnutrition? A secondary analysis of a randomized controlled trial

    Open Access•Clarisse Dah, Ourohiré Millogo et al.•ARTICLE•Maternal and Child Nutrition•2022

    Mid-upper arm circumference (MUAC) < 11.5 cm and weight-for-height Z-score (WHZ) < -3 are used for screening for severe acute malnutrition (SAM). Underweight and concurrent wasting and stunting may better target those at the highest risk of mortality. We compared anthropometric outcomes in children enrolled in a trial of antibiotics for SAM based on categories of baseline anthropometry, including indicators for programme admission (WHZ < -3, MUAC…

  • Comparison of door-to-door and fixed-point delivery of azithromycin distribution for child survival in Niger

    Open Access•Ahmed M Arzika, Ramatou Maliki et al.•ARTICLE•PLOS Global Public Health•2023

    Recent evidence indicates mass azithromycin distribution reduces under-5 mortality. This intervention is being considered for child survival programs in high mortality sub-Saharan African settings. The delivery approach used in prior studies required a full-time census and distribution team, which is not feasible for most programs. To determine the optimal programmatic approach to delivery, this study aimed to compare treatment coverage, costs, a…

  • Infant mortality and growth failure after oral azithromycin among low birthweight and underweight neonates

    Open Access•Mamadou Bountogo, Ali Sié et al.•ARTICLE•PLOS Global Public Health•2023

    Background Low birthweight (birthweight Methods Infants aged 8–27 days of age weighing ≥2500 g at enrollment in Burkina Faso were randomized 1:1 to a single, oral dose of azithromycin (20 mg/kg) or matching placebo. We evaluated mortality and anthropometric outcomes in four subgroups: 1) both low birthweight and underweight at enrollment; 2) low birthweight-only; 3) underweight-only; 4) neither low birthweight nor underweight. Findings Of 21,832 …

  • Mass azithromycin for prevention of child mortality among children with acute malnutrition

    Open Access•Ali Sié, Mamadou Ouattara et al.•ARTICLE•PLOS Global Public Health•2024

    Children with acute malnutrition are at high risk of morality. Mass azithromycin distribution reduces all-cause mortality among children aged 1–59 months, and effects may be greater in underweight infants. Here, we evaluate the efficacy of azithromycin for reducing all-cause mortality in children aged 6–59 months with acute malnutrition (mid-upper arm circumference, MUAC, P -value for interaction on the relative scale = 0.09; P -value for interac…

  • Neonatal anthropometric indicators of infant growth and mortality in Burkina Faso

    Open Access•Mamadou Bountogo, Ali Sié et al.•ARTICLE•Public Health Nutrition•2024

    Objective: Most evidence supporting screening for undernutrition is for children aged 6–59 months. However, the highest risk of mortality and highest incidence of wasting occurs in the first 6 months of life. We evaluated relationships between neonatal anthropometric indicators, including birth weight, weight-for-age Z -score (WAZ), weight-for-length Z-score (WLZ), length-for-age Z -score (LAZ) and mid-upper arm circumference (MUAC) and mortality…

  • Seasonality of underweight among infants 1–11 months old in Niger

    Open Access•Brittany Peterson, Ahmed M Arzika et al.•ARTICLE•BMJ Global Health•2025

    INTRODUCTION: Malnutrition is a risk factor for child mortality, with around 45% of deaths in children under 5 globally linked to malnutrition. Seasonality of malnutrition has important implications for the timing of child health programme activities, but evidence is mixed on the nature of such patterns. Moreover, the bulk of the existing evidence is focused on wasting and stunting in children 6-59 months, despite increasing evidence that younger…

  • Effect of biannual azithromycin on respiratory pathogens among symptomatic children

    Open Access•Jie Liu, Stephanie A Brennhofer et al.•ARTICLE•BMJ Global Health•2025

    Introduction Biannual (ie, every 6 months) mass drug administration of azithromycin has reduced childhood mortality in Niger, but its effects on specific respiratory pathogens are not fully elucidated. Methods Across 2 years of the Macrolides Oraux pour Réduire les Décès avec un Oeil sur la Résistance (MORDOR) study in Niger, we evaluated 1468 nasopharyngeal swabs from children who presented for care with respiratory symptoms. Swabs were tested b…

  • The role of seasonal malaria chemoprevention in the effect of azithromycin on child mortality

    Open Access•Elisabeth Gebreegziabher, Mamadou Ouattara et al.•ARTICLE•PLOS Global Public Health•2025

    The objective of this study was to examine whether the effect of mass Azithromycin (AZ) distribution on all-cause mortality among children under 5 varies with seasonal malaria chemoprevention (SMC) administration season or coverage. This was a secondary analysis of the Community Health with Azithromycin Trial (CHAT), a cluster-randomized, placebo-controlled trial of twice-yearly AZ treatment in 341 communities in the Nouna District, Burkina Faso.…

  • Micro-costing for national-scale azithromycin mass drug administration to improve child survival in Niger

    Open Access•Brittany Peterson, William Nguyen et al.•ARTICLE•PLOS Global Public Health•2026

    As programs for azithromycin mass drug administration (AZ-MDA) to reduce child mortality have begun in some parts of West Africa, it is imperative to understand their financial costs. We combined a micro-costing framework and observations from an implementation-focused sub-study within the AVENIR trials in 80 communities in the Dosso region of Niger to estimate the national health sector financial costs of a scaled-up programmatic approach for az…

  • Integration of azithromycin mass administration to 1–11-month-old children into an existing health platform to reduce child mortality

    Open Access•Fanny Yago-Wienne, Djeinam Touré et al.•ARTICLE•BMJ Global Health•2026

    BACKGROUND: Azithromycin mass drug administration (MDA) to ages 1-59 months can reduce childhood mortality; however, more evidence is needed to support targeting a narrower age range of 1-11 months. This trial assesses the efficacy of azithromycin MDA to 1-11-month-old children in reducing mortality in a real-world setting with integration of vitamin A delivery within the established Child Health Days platform in Burkina Faso. METHODS: Mortalite …

  • Predictors of home- vs . facility-based delivery among women living in rural Niger

    Open Access•Brittany Peterson, Ahmed M Arzika et al.•ARTICLE•Journal of Global Health•2026

    Background: Niger has one of the highest maternal mortality rates, and facility delivery can help prevent these deaths. While distance to health facilities predicts home delivery in other sub-Saharan African settings, few studies have examined this relationship in Niger. Methods: This cross-sectional survey, an ancillary study to the AVENIR trial, included women aged 12-59 years old with a child participating in a sub-trial of AVENIR. Trained wor…

  • Caregiver Screening for Relapse Among Children Recently Recovered From Severe Acute Malnutrition

    Open Access•Mamadou Bountogo, Clarisse Dah et al.•ARTICLE•Maternal and Child Nutrition•2026

    Relapse to acute malnutrition after recovery from severe acute malnutrition (SAM) is common. However, most programmatic resources are devoted to the acute phase of recovery, and fewer interventions are available for children recently discharged from outpatient nutritional programs. We evaluated the feasibility of training caregivers to screen for relapse using mid-upper arm circumference (MUAC) tapes for reducing time to detection of relapse amon…

Azithromycin (9 obras) · Medicine (9 obras) · Randomized controlled trial (8 obras) · Child Nutrition and Water Access (7 obras) · Internal Medicine (7 obras) · Pediatrics (7 obras) · Global Maternal and Child Health (6 obras) · Body mass index (5 obras) · Confidence interval (5 obras) · Overweight (5 obras)

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