David E Minnikin
Datos Biográficos
| ID | 6450159 |
|---|---|
| NOMBRE | David E Minnikin |
| NOMBRES | David E |
| APELLIDO | Minnikin |
| FIRMA | MINNIKIN D E |
| AFILIACIONES | University of Birmingham |
| ORCID | 0000-0002-9486-8999 |
| VERIFICADO | Sí |
| TOTAL DE OBRAS | 8 |
| TOTAL DE CITAS | 22 |
| TOTAL COMO AUTOR | 8 |
| TOTAL COMO EDITOR | 0 |
| PRIMER AÑO DE PUBLICACIÓN | 1998 |
| AÑO MÁS RECIENTE DE PUBLICACIÓN | 2020 |
| ÍNDICE H | 3 |
Recognising the broad array of approaches available for the diagnosis of ancient tuberculosis
The characterisation of ancient tuberculosis is not totally dependent on the recovery of intact genomes. Judicious combinations of ancient DNA fragments and specific lipid biomarkers provide unambiguous diagnosis and these protocols are capable of refinement and extension. Currently, there is no direct evidence for exclusive co-evolution of humans and tuberculosis. A developing body of data suggests that the initial evolution of tuberculosis may …
Éves Dél-Magyarországi Tuberkulózis Esetek Oszteológiai És Molekuláris Biológiai Vizsgálata
This study derives from the macroscopic analysis of a Late Neolithic population from southern Hungary. Remains were recovered from a tell settlement at Hódmezővásárhely-Gorzsa from graves within the settlement as well as pits, ditches, houses and as stray finds. Pathological analysis of the 71 individuals revealed numerous cases of infections and non-specific stress indicators, metabolic diseases, and evidence of trauma and mechanical changes. Se…
The challenge of identifying tuberculosis proteins in archaeological tissues
Essentials in the use of mycolic acid biomarkers for tuberculosis detection
Biomolecular archaeology of ancient tuberculosis
Mycobacterium leprae genotype amplified from an archaeological case of lepromatous leprosy in Central Asia
Detection and Molecular Characterization of 9000-Year-Old Mycobacterium tuberculosis from a Neolithic Settlement in the Eastern Mediterranean
BACKGROUND: Mycobacterium tuberculosis is the principal etiologic agent of human tuberculosis. It has no environmental reservoir and is believed to have co-evolved with its host over millennia. This is supported by skeletal evidence of the disease in early humans, and inferred from M. tuberculosis genomic analysis. Direct examination of ancient human remains for M. tuberculosis biomarkers should aid our understanding of the nature of prehistoric …
Detecting Ancient Tuberculosis
Some diseases have played a more significant role in human development than others. Here we describe the results of a trial to diagnose ancient tuberculosis using chemical methods. Palaeo-epidemiological studies of the disease are compromised, but it has become apparent that tuberculosis (TB) is a 'population-density dependent' disease. From modern studies, it is also apparent that the prevalence of TB can be used as an indicator of the level of …
Biomolecular archaeology of ancient tuberculosis
The challenge of identifying tuberculosis proteins in archaeological tissues
Mycobacterium leprae genotype amplified from an archaeological case of lepromatous leprosy in Central Asia
Essentials in the use of mycolic acid biomarkers for tuberculosis detection
Detecting Ancient Tuberculosis
Some diseases have played a more significant role in human development than others. Here we describe the results of a trial to diagnose ancient tuberculosis using chemical methods. Palaeo-epidemiological studies of the disease are compromised, but it has become apparent that tuberculosis (TB) is a 'population-density dependent' disease. From modern studies, it is also apparent that the prevalence of TB can be used as an indicator of the level of …
Detection and Molecular Characterization of 9000-Year-Old Mycobacterium tuberculosis from a Neolithic Settlement in the Eastern Mediterranean
BACKGROUND: Mycobacterium tuberculosis is the principal etiologic agent of human tuberculosis. It has no environmental reservoir and is believed to have co-evolved with its host over millennia. This is supported by skeletal evidence of the disease in early humans, and inferred from M. tuberculosis genomic analysis. Direct examination of ancient human remains for M. tuberculosis biomarkers should aid our understanding of the nature of prehistoric …
Biomolecular archaeology of ancient tuberculosis
Mycobacterium leprae genotype amplified from an archaeological case of lepromatous leprosy in Central Asia
Essentials in the use of mycolic acid biomarkers for tuberculosis detection
Éves Dél-Magyarországi Tuberkulózis Esetek Oszteológiai És Molekuláris Biológiai Vizsgálata
This study derives from the macroscopic analysis of a Late Neolithic population from southern Hungary. Remains were recovered from a tell settlement at Hódmezővásárhely-Gorzsa from graves within the settlement as well as pits, ditches, houses and as stray finds. Pathological analysis of the 71 individuals revealed numerous cases of infections and non-specific stress indicators, metabolic diseases, and evidence of trauma and mechanical changes. Se…
The challenge of identifying tuberculosis proteins in archaeological tissues
Recognising the broad array of approaches available for the diagnosis of ancient tuberculosis
The characterisation of ancient tuberculosis is not totally dependent on the recovery of intact genomes. Judicious combinations of ancient DNA fragments and specific lipid biomarkers provide unambiguous diagnosis and these protocols are capable of refinement and extension. Currently, there is no direct evidence for exclusive co-evolution of humans and tuberculosis. A developing body of data suggests that the initial evolution of tuberculosis may …
Biology (7 obras) · Tuberculosis Research and Epidemiology (7 obras) · Medicine (6 obras) · Pathology (6 obras) · Tuberculosis (6 obras) · Archaeology (4 obras) · Infectious Diseases and Tuberculosis (4 obras) · Mycobacterium tuberculosis (4 obras) · Ancient DNA (3 obras) · Mycobacterium research and diagnosis (3 obras)