Patrizio Pezzotti
Datos Biográficos
| ID | 6652559 |
|---|---|
| NOMBRE | Patrizio Pezzotti |
| NOMBRES | Patrizio |
| APELLIDO | Pezzotti |
| FIRMA | PEZZOTTI P |
| AFILIACIONES | Istituto Superiore di Sanità |
| ORCID | 0000-0002-0805-2927 |
| VERIFICADO | Sí |
| TOTAL DE OBRAS | 23 |
| TOTAL DE CITAS | 2 |
| TOTAL COMO AUTOR | 23 |
| TOTAL COMO EDITOR | 0 |
| PRIMER AÑO DE PUBLICACIÓN | 1989 |
| AÑO MÁS RECIENTE DE PUBLICACIÓN | 2026 |
| ÍNDICE H | 1 |
Inequalities in severe Covid-19 by socioeconomic deprivation and country of birth, Italy, 2021–2024
Global evidence on COVID-19 related inequalities remains temporally fragmented. In this study we investigated how the associations of socioeconomic deprivation (SED) and country of birth with severe COVID-19 evolved in COVID-19 vaccinated persons residing in small/medium sized municipalities in Italy in 2021–2024. We retrospectively analysed data of 22,131,245 adults, living in municipalities with <50,000 residents, extracted from the national CO…
Increasing situational awareness through nowcasting of the reproduction number
Background: The time-varying reproduction number R is a critical variable for situational awareness during infectious disease outbreaks; however, delays between infection and reporting of cases hinder its accurate estimation in real-time. A number of nowcasting methods, leveraging available information on data consolidation delays, have been proposed to mitigate this problem. Methods: In this work, we retrospectively validate the use of a nowcast…
Risk of breakthrough infection and hospitalisation after Covid-19 primary vaccination by HIV status in four Italian regions during 2021
Our findings suggest PLWH were not at increased risk of breakthrough SARS-CoV-2 infection or COVID-19 hospitalisation following a primary cycle of mRNA vaccination
Socioeconomic Inequalities in Sars-CoV-2 Infection and Covid-19 Health Outcomes in Urban Italy During the Covid-19 Vaccine Rollout, January–November 2021
This study analysed the evolution of the association of socioeconomic deprivation (SED) with SARS-CoV-2 infection and COVID-19 outcomes in urban Italy during the vaccine rollout in 2021. We conducted a retrospective cohort analysis between January and November 2021, comprising of 16,044,530 individuals aged ≥ 20 years, by linking national COVID-19 surveillance system data to the Italian SED index calculated at census block level. We estimated inc…
Geographic heterogeneity of the epidemiological impact of the Covid-19 pandemic in Italy using a socioeconomic proxy-based classification of the national territory
Objectives: This study aimed to evaluate the differences in incidence, non-intensive care unit (non-ICU) and intensive care unit (ICU) hospital admissions, and COVID-19-related mortality between the "inner areas" of Italy and its metropolitan areas. Study design: Retrospective population-based study conducted from the beginning of the pandemic in Italy (20 February 2020) to 31 March 2022. Methods: The municipalities of Italy were classified into …
Socio-Economic Factors Associated with Ethnic Disparities in Sars-CoV-2 Infection and Hospitalization
COVID-19 had unequal health outcomes among the population in Umbria. Reduced access to primary care services in the non-Italian group could explain our findings. Policies on immigrants' access to primary healthcare need to be improved
Covid-19 vaccination effectiveness in the population of Friuli Venezia Giulia, North-East Italy. Control of bias associated with divergent compliance to policies in a test-negative case-control study
The study suggests that, under similar TNCC settings, mediation analysis and adjustment for number of diagnostic tests should be included, as an effective approach to the challenge of differential testing behavior that may determine substantial selection bias. This correction allowed us to align with results from other studies that show how full-cycle VE against infection was initially high but decreased over time by variant circulation, counterb…
The Impact of the First Wave of the Covid-19 Pandemic on Healthcare Workers
Healthcare workers (HCWs) played an essential role in managing the COVID-19 pandemic. The Italian Workers' Compensation Authority (INAIL) and the Italian National Institute of Health (ISS) developed a retrospective study to analyze and understand trends and characteristics of infections among HCWs during the first wave of the pandemic. Between May and September 2020, Italian Regions retrospectively collected anonymous data regarding HCWs infected…
Assessing Covid-19-Related Excess Mortality Using Multiple Approaches—Italy, 2020–2021
Presently, an unambiguous explanation of EM in Italy is not possible. We provide a range that we consider sound, given the high variability associated with the use of different models. However, all three models accurately represented the spatiotemporal trends of the pandemic waves in Italy
Excess Mortality in Italy During the Covid-19 Pandemic
COVID-19 dramatically influenced mortality worldwide, in Italy as well, the first European country to experience the Sars-Cov2 epidemic. Many countries reported a two-wave pattern of COVID-19 deaths; however, studies comparing the two waves are limited. The objective of the study was to compare all-cause excess mortality between the two waves that occurred during the year 2020 using nationwide data. All-cause excess mortalities were estimated usi…
Socioeconomic patterns and Covid-19 outcomes before, during and after the lockdown in Italy (2020)
The objective was to investigate the association between deprivation and COVID-19 outcomes in Italy during pre-lockdown, lockdown and post-lockdown periods using a retrospective cohort study with 38,534,169 citizens and 222,875 COVID-19 cases. Multilevel negative binomial regression models, adjusting for age, sex, population-density and region of residence were conducted to evaluate the association between area-level deprivation and COVID-19 inci…
West Nile virus in Europe
BACKGROUND: After Action Reviews (AAR) with a One Health perspective were performed in Slovenia, Italy, Serbia and Greece following a severe West Nile virus (WNV) transmission season in 2018. A protocol combining traditional techniques and organizational process analysis was developed and then implemented in each country. RESULTS: In 2018, response to the unusually intense transmission season of WNV in Slovenia, Italy, Serbia and Greece took plac…
Temporal dynamics in total excess mortality and Covid-19 deaths in Italian cities
An underestimation of COVID-19 deaths is particularly evident among the elderly. When quantifying the burden in mortality related to COVID-19, it is important to consider seasonal dynamics in mortality. Surveillance data provides an impartial indicator for monitoring the following phases of the epidemic, and may help in the evaluation of mitigation measures adopted
People diagnosed with HIV and in care in Italy in 2014
We conducted a second National survey in all Italian Infectious Disease clinics to assess the number of people diagnosed and linked to care and, among these, the number of people on antiretroviral therapy and viral load suppressed. In 2014, 100,049 (0.16 per 100 residents) people diagnosed and linked to care were estimated, corresponding to an increase of 6.3% compared to the survey conducted in 2012. Among people diagnosed and linked to care, 91…
HIV rapid testing in the framework of an STI prevention project on a cohort of vulnerable Italians and immigrants
INTRODUCTION: Uptake of HIV tests is a challenging issue in vulnerable populations including immigrants, normally using standard diagnostic tools. Objectives of this study were to evaluate the acceptability of HIV rapid test; estimate the percentage of newly HIV diagnoses and evaluate knowledge, attitudes and perception (KAP) about HIV/AIDS and other STIs in a specific set of immigrants and vulnerable population in Rome (Italy). METHODS: All immi…
Vaccine coverage and determinants of incomplete vaccination in children aged 12–23 months in Dschang, West Region, Cameroon
Vaccination coverage was high; however, 1 out of 7 children was partially vaccinated, and 1 out of 4 did not complete timely the recommended vaccinations. In order to improve the immunization coverage, it is necessary to strengthen ANC services, and to improve parents' information and attitude towards immunization, targeting younger parents and families living far away from vaccination centers, using appropriate communication strategies. Finally,…
Percentage and determinants of missed HIV testing in pregnancy
HIV testing is recommended as part of routine preconception and prenatal care but some cases of vertical transmission still occur because of missed HIV testing in pregnancy. We estimated the percentage of women missing HIV testing before delivery, and we evaluated factors related with it. An anonymous survey was distributed to women giving birth during a two-week period in the maternity units of hospitals in the Lazio region of Italy in 2011. Amo…
Characteristics and behaviors in a sample of patients unaware of their infection until Aids diagnosis in Italy
The objective of this study was to define the sociodemographic and behavioral characteristics of people unaware of being HIV-positive at AIDS diagnosis. A multi-center cross-sectional study was conducted in 11 Italian centers of infectious diseases, recruited on a voluntary basis. Each center enrolled individuals diagnosed with AIDS aged ≥ 18 years from May 2003 to December 2005. The patients were classified into two groups on the basis of the am…
Can we use the pharmacy data to estimate the prevalence of chronic conditions? a comparison of multiple data sources
Our study showed that PD can be used to provide reliable prevalence estimates of several CCs in the general population
Increasing proportion of late testers among Aids cases in Italy, 1996–2002
In recent years, the proportion of individuals who are unaware of being infected with HIV when diagnosed with AIDS (defined as 'late testers') has dramatically increased in several European countries, including Italy. We evaluated the extent and determinants of late testing and its impact in terms of AIDS-defining illnesses among AIDS cases reported to the Italian National AIDS Registry since 1996. Late testers were defined as those persons whose…
Knowledge, Perceptions and Behaviour of Mothers toward Intestinal Helminths in Upper Egypt
Operational research was conducted in Qena Governorate, Upper Egypt, to gather the information needed to design an integrated control programme for intestinal helminths in the area. To this aim, qualitative and quantitative techniques were used on a sample representative of the entire governorate. Mothers were questioned about their knowledge and perception of intestinal helminths, their hygienic habits and health-seeking behaviour. At the same t…
HIV/Aids surveillance in Italy
HIV/AIDS surveillance in Italy: the potential misinterpretation of time trends. P Pezzotti, C Piovesan, G Rezza, and P FerraroCopyRight https://doi.org/10.2105/AJPH.87.3.469 Published Online: October 07, 2011
The Italian Aids ‘hot-line’
The Italian AIDS hot-line has recently completed its first two operational years. Established as an emergency service, it was initially overloaded with calls, under the emotional impact of a new disease. As the average number of calls settled to around a hundred per day, a wider approach aimed at the concerns raised by callers has been possible. A particular effort has been made to handle psychological and social aspects of HIV infections. A larg…
Socioeconomic patterns and Covid-19 outcomes before, during and after the lockdown in Italy (2020)
The objective was to investigate the association between deprivation and COVID-19 outcomes in Italy during pre-lockdown, lockdown and post-lockdown periods using a retrospective cohort study with 38,534,169 citizens and 222,875 COVID-19 cases. Multilevel negative binomial regression models, adjusting for age, sex, population-density and region of residence were conducted to evaluate the association between area-level deprivation and COVID-19 inci…
Knowledge, Perceptions and Behaviour of Mothers toward Intestinal Helminths in Upper Egypt
Operational research was conducted in Qena Governorate, Upper Egypt, to gather the information needed to design an integrated control programme for intestinal helminths in the area. To this aim, qualitative and quantitative techniques were used on a sample representative of the entire governorate. Mothers were questioned about their knowledge and perception of intestinal helminths, their hygienic habits and health-seeking behaviour. At the same t…
The Italian Aids ‘hot-line’
The Italian AIDS hot-line has recently completed its first two operational years. Established as an emergency service, it was initially overloaded with calls, under the emotional impact of a new disease. As the average number of calls settled to around a hundred per day, a wider approach aimed at the concerns raised by callers has been possible. A particular effort has been made to handle psychological and social aspects of HIV infections. A larg…
HIV/Aids surveillance in Italy
HIV/AIDS surveillance in Italy: the potential misinterpretation of time trends. P Pezzotti, C Piovesan, G Rezza, and P FerraroCopyRight https://doi.org/10.2105/AJPH.87.3.469 Published Online: October 07, 2011
Knowledge, Perceptions and Behaviour of Mothers toward Intestinal Helminths in Upper Egypt
Operational research was conducted in Qena Governorate, Upper Egypt, to gather the information needed to design an integrated control programme for intestinal helminths in the area. To this aim, qualitative and quantitative techniques were used on a sample representative of the entire governorate. Mothers were questioned about their knowledge and perception of intestinal helminths, their hygienic habits and health-seeking behaviour. At the same t…
Increasing proportion of late testers among Aids cases in Italy, 1996–2002
In recent years, the proportion of individuals who are unaware of being infected with HIV when diagnosed with AIDS (defined as 'late testers') has dramatically increased in several European countries, including Italy. We evaluated the extent and determinants of late testing and its impact in terms of AIDS-defining illnesses among AIDS cases reported to the Italian National AIDS Registry since 1996. Late testers were defined as those persons whose…
Characteristics and behaviors in a sample of patients unaware of their infection until Aids diagnosis in Italy
The objective of this study was to define the sociodemographic and behavioral characteristics of people unaware of being HIV-positive at AIDS diagnosis. A multi-center cross-sectional study was conducted in 11 Italian centers of infectious diseases, recruited on a voluntary basis. Each center enrolled individuals diagnosed with AIDS aged ≥ 18 years from May 2003 to December 2005. The patients were classified into two groups on the basis of the am…
Can we use the pharmacy data to estimate the prevalence of chronic conditions? a comparison of multiple data sources
Our study showed that PD can be used to provide reliable prevalence estimates of several CCs in the general population
Percentage and determinants of missed HIV testing in pregnancy
HIV testing is recommended as part of routine preconception and prenatal care but some cases of vertical transmission still occur because of missed HIV testing in pregnancy. We estimated the percentage of women missing HIV testing before delivery, and we evaluated factors related with it. An anonymous survey was distributed to women giving birth during a two-week period in the maternity units of hospitals in the Lazio region of Italy in 2011. Amo…
Vaccine coverage and determinants of incomplete vaccination in children aged 12–23 months in Dschang, West Region, Cameroon
Vaccination coverage was high; however, 1 out of 7 children was partially vaccinated, and 1 out of 4 did not complete timely the recommended vaccinations. In order to improve the immunization coverage, it is necessary to strengthen ANC services, and to improve parents' information and attitude towards immunization, targeting younger parents and families living far away from vaccination centers, using appropriate communication strategies. Finally,…
HIV rapid testing in the framework of an STI prevention project on a cohort of vulnerable Italians and immigrants
INTRODUCTION: Uptake of HIV tests is a challenging issue in vulnerable populations including immigrants, normally using standard diagnostic tools. Objectives of this study were to evaluate the acceptability of HIV rapid test; estimate the percentage of newly HIV diagnoses and evaluate knowledge, attitudes and perception (KAP) about HIV/AIDS and other STIs in a specific set of immigrants and vulnerable population in Rome (Italy). METHODS: All immi…
People diagnosed with HIV and in care in Italy in 2014
We conducted a second National survey in all Italian Infectious Disease clinics to assess the number of people diagnosed and linked to care and, among these, the number of people on antiretroviral therapy and viral load suppressed. In 2014, 100,049 (0.16 per 100 residents) people diagnosed and linked to care were estimated, corresponding to an increase of 6.3% compared to the survey conducted in 2012. Among people diagnosed and linked to care, 91…
West Nile virus in Europe
BACKGROUND: After Action Reviews (AAR) with a One Health perspective were performed in Slovenia, Italy, Serbia and Greece following a severe West Nile virus (WNV) transmission season in 2018. A protocol combining traditional techniques and organizational process analysis was developed and then implemented in each country. RESULTS: In 2018, response to the unusually intense transmission season of WNV in Slovenia, Italy, Serbia and Greece took plac…
Temporal dynamics in total excess mortality and Covid-19 deaths in Italian cities
An underestimation of COVID-19 deaths is particularly evident among the elderly. When quantifying the burden in mortality related to COVID-19, it is important to consider seasonal dynamics in mortality. Surveillance data provides an impartial indicator for monitoring the following phases of the epidemic, and may help in the evaluation of mitigation measures adopted
Excess Mortality in Italy During the Covid-19 Pandemic
COVID-19 dramatically influenced mortality worldwide, in Italy as well, the first European country to experience the Sars-Cov2 epidemic. Many countries reported a two-wave pattern of COVID-19 deaths; however, studies comparing the two waves are limited. The objective of the study was to compare all-cause excess mortality between the two waves that occurred during the year 2020 using nationwide data. All-cause excess mortalities were estimated usi…
Socioeconomic patterns and Covid-19 outcomes before, during and after the lockdown in Italy (2020)
The objective was to investigate the association between deprivation and COVID-19 outcomes in Italy during pre-lockdown, lockdown and post-lockdown periods using a retrospective cohort study with 38,534,169 citizens and 222,875 COVID-19 cases. Multilevel negative binomial regression models, adjusting for age, sex, population-density and region of residence were conducted to evaluate the association between area-level deprivation and COVID-19 inci…
The Impact of the First Wave of the Covid-19 Pandemic on Healthcare Workers
Healthcare workers (HCWs) played an essential role in managing the COVID-19 pandemic. The Italian Workers' Compensation Authority (INAIL) and the Italian National Institute of Health (ISS) developed a retrospective study to analyze and understand trends and characteristics of infections among HCWs during the first wave of the pandemic. Between May and September 2020, Italian Regions retrospectively collected anonymous data regarding HCWs infected…
Assessing Covid-19-Related Excess Mortality Using Multiple Approaches—Italy, 2020–2021
Presently, an unambiguous explanation of EM in Italy is not possible. We provide a range that we consider sound, given the high variability associated with the use of different models. However, all three models accurately represented the spatiotemporal trends of the pandemic waves in Italy
Geographic heterogeneity of the epidemiological impact of the Covid-19 pandemic in Italy using a socioeconomic proxy-based classification of the national territory
Objectives: This study aimed to evaluate the differences in incidence, non-intensive care unit (non-ICU) and intensive care unit (ICU) hospital admissions, and COVID-19-related mortality between the "inner areas" of Italy and its metropolitan areas. Study design: Retrospective population-based study conducted from the beginning of the pandemic in Italy (20 February 2020) to 31 March 2022. Methods: The municipalities of Italy were classified into …
Socio-Economic Factors Associated with Ethnic Disparities in Sars-CoV-2 Infection and Hospitalization
COVID-19 had unequal health outcomes among the population in Umbria. Reduced access to primary care services in the non-Italian group could explain our findings. Policies on immigrants' access to primary healthcare need to be improved
Covid-19 vaccination effectiveness in the population of Friuli Venezia Giulia, North-East Italy. Control of bias associated with divergent compliance to policies in a test-negative case-control study
The study suggests that, under similar TNCC settings, mediation analysis and adjustment for number of diagnostic tests should be included, as an effective approach to the challenge of differential testing behavior that may determine substantial selection bias. This correction allowed us to align with results from other studies that show how full-cycle VE against infection was initially high but decreased over time by variant circulation, counterb…
Increasing situational awareness through nowcasting of the reproduction number
Background: The time-varying reproduction number R is a critical variable for situational awareness during infectious disease outbreaks; however, delays between infection and reporting of cases hinder its accurate estimation in real-time. A number of nowcasting methods, leveraging available information on data consolidation delays, have been proposed to mitigate this problem. Methods: In this work, we retrospectively validate the use of a nowcast…
Risk of breakthrough infection and hospitalisation after Covid-19 primary vaccination by HIV status in four Italian regions during 2021
Our findings suggest PLWH were not at increased risk of breakthrough SARS-CoV-2 infection or COVID-19 hospitalisation following a primary cycle of mRNA vaccination
Socioeconomic Inequalities in Sars-CoV-2 Infection and Covid-19 Health Outcomes in Urban Italy During the Covid-19 Vaccine Rollout, January–November 2021
This study analysed the evolution of the association of socioeconomic deprivation (SED) with SARS-CoV-2 infection and COVID-19 outcomes in urban Italy during the vaccine rollout in 2021. We conducted a retrospective cohort analysis between January and November 2021, comprising of 16,044,530 individuals aged ≥ 20 years, by linking national COVID-19 surveillance system data to the Italian SED index calculated at census block level. We estimated inc…
Inequalities in severe Covid-19 by socioeconomic deprivation and country of birth, Italy, 2021–2024
Global evidence on COVID-19 related inequalities remains temporally fragmented. In this study we investigated how the associations of socioeconomic deprivation (SED) and country of birth with severe COVID-19 evolved in COVID-19 vaccinated persons residing in small/medium sized municipalities in Italy in 2021–2024. We retrospectively analysed data of 22,131,245 adults, living in municipalities with <50,000 residents, extracted from the national CO…
Medicine (22 obras) · Demography (16 obras) · Environmental health (15 obras) · Internal Medicine (15 obras) · Population (13 obras) · Disease (11 obras) · COVID-19 epidemiological studies (9 obras) · Demography (9 obras) · Pandemic (9 obras) · Coronavirus disease 2019 (COVID-19 (8 obras)