Thembelihle Zuma
Datos Biográficos
| ID | 6722968 |
|---|---|
| NOMBRE | Thembelihle Zuma |
| NOMBRES | Thembelihle |
| APELLIDO | Zuma |
| FIRMA | ZUMA T |
| AFILIACIONES | Africa Health Research Institute |
| ORCID | 0000-0002-8374-2354 |
| VERIFICADO | Sí |
| TOTAL DE OBRAS | 28 |
| TOTAL DE CITAS | 0 |
| TOTAL COMO AUTOR | 28 |
| TOTAL COMO EDITOR | 0 |
| PRIMER AÑO DE PUBLICACIÓN | 2016 |
| AÑO MÁS RECIENTE DE PUBLICACIÓN | 2026 |
| ÍNDICE H | 0 |
Harnessing the social capital of rural communities for adolescent and youth biosocial HIV prevention
Novel interventions are required to reduce risky sexual behavior among adolescents and young people (AYP). We interviewed a purposive sample comprising AYP residing in the Africa Health Research Institute’s surveillance area and individuals involved in delivering a community-based peer navigator support intervention. Interviews were conducted in isiZulu, transcribed and translated into English for thematic analysis. We found that community resili…
Long-acting HIV pre-exposure prophylaxis integrated with community-based sexual and reproductive health services in South Africa (Lapis)
ClinicalTrials.gov Identifier-NCT06250504. Registered: 01 February 2024
The effect of multi-level HIV prevention interventions on common mental disorders among adolescents and young adults in rural South Africa
This study evaluated the effect of multi-level HIV prevention interventions delivered through DREAMS (Determined, Resilient, Empowered, AIDS-free, Motivated, and Safe) program on common mental disorders (CMD) among adolescents and young adults (AYA) in rural South Africa. We used longitudinal data from two cohorts of AYA aged 13–35 years (N = 2184 for cohort 1 and N = 3067 for cohort 2), recruited between May 2017 and December 2018, with data col…
Understanding the mental health of adolescents and young adults in rural South Africa through participatory research
Most mental health problems in adulthood begin during adolescence. Factors such as poverty, violence, and unemployment contribute to the high burden of mental health problems. In Africa, the lack of resources for diagnosis, treatment, and management exacerbates the situation. Research on adolescent mental health has mostly focused on negative psychological effects, while positive attributes like coping, resilience, and emotional growth have been …
Challenges and opportunities in achieving sustainable development goal 3 in KwaZulu-Natal
South Africa is committed to achieving Sustainable Development Goal 3 (SDG 3), which aims to ensure health and well-being for all. However, in rural provinces like KwaZulu-Natal, structural inequalities, socio-cultural challenges, and environmental stressors hinder progress. This study synthesises findings from qualitative research conducted at the Africa Health Research Institute (AHRI) to explore the challenges and opportunities in meeting SDG …
Alcohol Use and the Pre-exposure Prophylaxis Continuum of Care Among Men in Rural South Africa
Despite freely available oral HIV pre-exposure prophylaxis (PrEP), HIV incidence among young men in South Africa remains high. This study explores the impact of alcohol use on PrEP initiation and continuation among South African men. We performed a secondary data analysis from a trial involving men aged 16-29, randomly selected in KwaZulu-Natal. Participants were referred to sexual health services, and those who were HIV negative and sexually act…
Uptake of multi-level HIV interventions and HIV-related behaviours among young people in rural South Africa
Combination HIV prevention packages have reduced HIV incidence and improved HIV-related outcomes among young people. However, there is limited data on how package components interact to promote HIV-related prevention behaviours. We described the uptake of HIV prevention interventions supported by Determined, Resilient, Empowered, AIDS-free, Motivated and Safe (DREAMS) Partnership and assessed the association between uptake and HIV-related behavio…
Increasing HIV testing and linkage to care among men in rural South Africa using conditional financial incentives and a decision support app
Men in sub-Saharan Africa are less likely to accept HIV testing and link to HIV care than women. We conducted a trial to investigate the impact of conditional financial incentives and a decision support application, called EPIC-HIV, on HIV testing and linkage to care. We report the findings of the trial process evaluation to explore whether the interventions were delivered as intended, identify mechanisms of impact and any contextual factors that…
Looking for the future – Hope and adolescent risk behaviour in rural KwaZulu-Natal, South Africa
We investigate the relationship between hope and risky behaviour and the role of migration among young people in northern KwaZulu-Natal, South Africa. We use data from a cohort of n = 5248 adolescents and young adults (AYA) aged 13-35 recruited and followed up in 2017-2019. We conducted a structured quantitative survey to assess levels of hope among AYA using a validated tool/scale. 44% of participants were aged 13-17 years, 63% were still in sch…
Effect of a Male-Targeted Digital Decision Support Application Aimed at Increasing Linkage to HIV Care Among Men
Incident pregnancy and mental health among adolescent girls and young women in rural KwaZulu-Natal, South Africa
Pregnancy can place adolescent girls and young women (AGYW) at risk of poor mental health. However, evidence linking youth pregnancy to mental health in resource-limited settings is limited, especially where HIV incidence is high. We analysed a population-representative cohort of AGYW aged 13-25 in rural KwaZulu-Natal to assess how adolescent pregnancy predicts subsequent mental health. Among 1851 respondents, incident pregnancy (self-reported pa…
Adaptation and pre-test of a shortened Stepping Stones and Creating Futures intervention focused on HIV for young men in rural South Africa
Men’s engagement in HIV prevention and treatment is suboptimal, including in South Africa. We sought to address this through adapting an evidence-based intervention, Stepping Stones and Creating Futures (SSCF), to strengthen its HIV content and provide a more scalable (shorter) intervention in rural South Africa. We then conducted a mixed methods pre-test of the intervention among young men aged 18–35 years. To adapt SSCF, we reviewed the current…
Thetha Nami ngithethe nawe (Let’s Talk)
ClinicalTrials.gov Identifier-NCT05405582. Registered: 6th June 2022
A socio-ecological approach to understanding experiences and perceptions of a multilevel HIV prevention intervention
Putting research ethics in context
We investigated conceptual shifts around vulnerability and ethical issues arising in research using a case study embedded within an HIV intervention project targeting adolescent girls and young women (AGYW) in a rural district, South Africa. We recruited 77 participants. Sixty-five people participated in focus group discussions (FGDs); nine in in-depth interviews (IDIs) and three in key informant interviews (KIIs). Data were analysed iteratively …
A qualitative investigation of facilitators and barriers to DREAMS uptake among adolescents with grandparent caregivers in rural KwaZulu-Natal, South Africa
Adolescents with grandparent caregivers have experienced challenges including the death of one or both parents due to HIV in sub-Saharan Africa. They may be left out of existing HIV prevention interventions targeting parents and children. We investigated the facilitators and barriers to DREAMS (Determined, Resilient, Empowered, AIDS-free, Mentored and Safe) programme uptake among adolescents with grandparent caregivers across different levels of …
Antiretroviral therapy based HIV prevention targeting young women who sell sex
Pre-Exposure Prophylaxis (PrEP) is a potential game-changer for HIV. We used PrEP introduction for Young Women Who Sell Sex (YWSS) in a rural South Africa district to understand community norms and PrEP coverage in YWSS. Between 2017 and 2018, we measured awareness and uptake of PrEP in a representative cohort of 2184 Adolescent Girls and Young Women (AGYW) aged 13-22. We conducted group discussions with young people and community members (19); k…
Isisekelo Sempilo study protocol for the effectiveness of HIV prevention embedded in sexual health with or without peer navigator support (Thetha Nami) to reduce prevalence of transmissible HIV amongs…
gov Identifier NCT04532307 . Registered: March 2020
Measuring transactional sex in different contexts
Background: Adolescent girls and young women across sub-Saharan Africa are at disproportionate risk of HIV infection compared to their male counterparts. Transactional sex has been identified as an important proximate risk for infection in this population. Definitions and measures of transactional sex vary, necessitating improved measures to better estimate prevalence across settings, over time, and to understand the mechanisms through which tran…
Thetha Nami
Local youth were able to use evidence to develop a contextually adapted peer-led intervention to deliver biosocial HIV prevention
Common mental disorders and HIV status in the context of DREAMS among adolescent girls and young women in rural KwaZulu-Natal, South Africa
We found high prevalence of probable CMD among AGYW in rural South Africa, but it was only associated with HIV serostatus when not controlling for HIV acquisition risk factors. Our findings highlight that improving mental health service access for AGYW at high risk for HIV acquisition might protect them. Interventions already reaching AGYW with CMD, such as DREAMS, can be used to deliver mental health services to reduce both CMD and HIV risks. Th…
Lives Interrupted
We examine data from young women and men in South Africa and young female sex workers in Uganda to explore the inequalities and hardships experienced during the COVID-19 pandemic and investigate the opportunities and ability presented to navigate in a virtual world to build an inclusive supportive future for young people on the move. We argue that against the backdrop of a fragile past, young people who see their today disturbed, tomorrow reshape…
Young people’s experiences of sexual and reproductive health interventions in rural KwaZulu-Natal, South Africa
Despite efforts to address HIV-infection, adolescents and young peoples' (AYP) engagement in interventions remains suboptimal. Guided by a risk protection framework we describe factors that support positive and negative experiences of HIV and SRH interventions among AYP in rural KwaZulu-Natal, South Africa, using data from: community mapping; repeat semi-structured individual interviews (n= 58 in 2017, n=50 in 2018, n=37 in 2019-2020); and group …
Home-based intervention to test and start (Hits) protocol
This trial was registered on 28 November 2018 on, identifier https://clinicaltrials.gov
Traditional health practitioners’ management of HIV/Aids in rural South Africa in the era of widespread antiretroviral therapy
BACKGROUND: Traditional health practitioners (THPs) have been identified as a key local resource in the fight against human immunodeficiency virus/acquired immune deficiency syndrome (HIV/AIDS) in South Africa. However, their approaches to the treatment of people living with HIV (PLHIV) have been met with scepticism by some biomedical practitioners amid increasing access to antiretroviral therapy (ART). OBJECTIVE: In light of this ambivalence, th…
Sin obras prominentes en esta página.
Men, masculinity, and engagement with treatment as prevention in KwaZulu-Natal, South Africa
Men's poorer engagement with healthcare generally and HIV care specifically, compared to women, is well-described. Within the HIV public health domain, interest is growing in universal test and treat (UTT) strategies. UTT strategies refer to the expansion of antiretroviral therapy (ART) in order to reduce onward transmission and incidence of HIV in a population, through a "treatment as prevention" (TasP). This paper focuses on how masculinity inf…
Community perceptions of repeat HIV-testing
In the context of the ANRS 12249 Treatment as Prevention (TasP) trial, we investigated perceptions of regular and repeat HIV-testing in rural KwaZulu-Natal (South Africa), an area of very high HIV prevalence and incidence. We conducted two qualitative studies, before (2010) and during the early implementation stages of the trial (2013-2014), to appreciate the evolution in community perceptions of repeat HIV-testing over this period of rapid chang…
“It is better to die”
The ANRS 12249 Treatment-as-Prevention (TasP) cluster-randomized trial in rural South Africa uses a "test and treat" approach. Home-based testing services and antiretroviral treatment initiation satellite clinics were implemented in every cluster as part of the trial. A social science research agenda was nested within TasP with the aim of understanding the social, economic and contextual factors that affect individuals, households, communities an…
Traditional health practitioners’ management of HIV/Aids in rural South Africa in the era of widespread antiretroviral therapy
BACKGROUND: Traditional health practitioners (THPs) have been identified as a key local resource in the fight against human immunodeficiency virus/acquired immune deficiency syndrome (HIV/AIDS) in South Africa. However, their approaches to the treatment of people living with HIV (PLHIV) have been met with scepticism by some biomedical practitioners amid increasing access to antiretroviral therapy (ART). OBJECTIVE: In light of this ambivalence, th…
Home-based intervention to test and start (Hits) protocol
This trial was registered on 28 November 2018 on, identifier https://clinicaltrials.gov
Young people’s experiences of sexual and reproductive health interventions in rural KwaZulu-Natal, South Africa
Despite efforts to address HIV-infection, adolescents and young peoples' (AYP) engagement in interventions remains suboptimal. Guided by a risk protection framework we describe factors that support positive and negative experiences of HIV and SRH interventions among AYP in rural KwaZulu-Natal, South Africa, using data from: community mapping; repeat semi-structured individual interviews (n= 58 in 2017, n=50 in 2018, n=37 in 2019-2020); and group …
Measuring transactional sex in different contexts
Background: Adolescent girls and young women across sub-Saharan Africa are at disproportionate risk of HIV infection compared to their male counterparts. Transactional sex has been identified as an important proximate risk for infection in this population. Definitions and measures of transactional sex vary, necessitating improved measures to better estimate prevalence across settings, over time, and to understand the mechanisms through which tran…
Thetha Nami
Local youth were able to use evidence to develop a contextually adapted peer-led intervention to deliver biosocial HIV prevention
Common mental disorders and HIV status in the context of DREAMS among adolescent girls and young women in rural KwaZulu-Natal, South Africa
We found high prevalence of probable CMD among AGYW in rural South Africa, but it was only associated with HIV serostatus when not controlling for HIV acquisition risk factors. Our findings highlight that improving mental health service access for AGYW at high risk for HIV acquisition might protect them. Interventions already reaching AGYW with CMD, such as DREAMS, can be used to deliver mental health services to reduce both CMD and HIV risks. Th…
Lives Interrupted
We examine data from young women and men in South Africa and young female sex workers in Uganda to explore the inequalities and hardships experienced during the COVID-19 pandemic and investigate the opportunities and ability presented to navigate in a virtual world to build an inclusive supportive future for young people on the move. We argue that against the backdrop of a fragile past, young people who see their today disturbed, tomorrow reshape…
A socio-ecological approach to understanding experiences and perceptions of a multilevel HIV prevention intervention
Putting research ethics in context
We investigated conceptual shifts around vulnerability and ethical issues arising in research using a case study embedded within an HIV intervention project targeting adolescent girls and young women (AGYW) in a rural district, South Africa. We recruited 77 participants. Sixty-five people participated in focus group discussions (FGDs); nine in in-depth interviews (IDIs) and three in key informant interviews (KIIs). Data were analysed iteratively …
A qualitative investigation of facilitators and barriers to DREAMS uptake among adolescents with grandparent caregivers in rural KwaZulu-Natal, South Africa
Adolescents with grandparent caregivers have experienced challenges including the death of one or both parents due to HIV in sub-Saharan Africa. They may be left out of existing HIV prevention interventions targeting parents and children. We investigated the facilitators and barriers to DREAMS (Determined, Resilient, Empowered, AIDS-free, Mentored and Safe) programme uptake among adolescents with grandparent caregivers across different levels of …
Antiretroviral therapy based HIV prevention targeting young women who sell sex
Pre-Exposure Prophylaxis (PrEP) is a potential game-changer for HIV. We used PrEP introduction for Young Women Who Sell Sex (YWSS) in a rural South Africa district to understand community norms and PrEP coverage in YWSS. Between 2017 and 2018, we measured awareness and uptake of PrEP in a representative cohort of 2184 Adolescent Girls and Young Women (AGYW) aged 13-22. We conducted group discussions with young people and community members (19); k…
Isisekelo Sempilo study protocol for the effectiveness of HIV prevention embedded in sexual health with or without peer navigator support (Thetha Nami) to reduce prevalence of transmissible HIV amongs…
gov Identifier NCT04532307 . Registered: March 2020
Adaptation and pre-test of a shortened Stepping Stones and Creating Futures intervention focused on HIV for young men in rural South Africa
Men’s engagement in HIV prevention and treatment is suboptimal, including in South Africa. We sought to address this through adapting an evidence-based intervention, Stepping Stones and Creating Futures (SSCF), to strengthen its HIV content and provide a more scalable (shorter) intervention in rural South Africa. We then conducted a mixed methods pre-test of the intervention among young men aged 18–35 years. To adapt SSCF, we reviewed the current…
Thetha Nami ngithethe nawe (Let’s Talk)
ClinicalTrials.gov Identifier-NCT05405582. Registered: 6th June 2022
Uptake of multi-level HIV interventions and HIV-related behaviours among young people in rural South Africa
Combination HIV prevention packages have reduced HIV incidence and improved HIV-related outcomes among young people. However, there is limited data on how package components interact to promote HIV-related prevention behaviours. We described the uptake of HIV prevention interventions supported by Determined, Resilient, Empowered, AIDS-free, Motivated and Safe (DREAMS) Partnership and assessed the association between uptake and HIV-related behavio…
Increasing HIV testing and linkage to care among men in rural South Africa using conditional financial incentives and a decision support app
Men in sub-Saharan Africa are less likely to accept HIV testing and link to HIV care than women. We conducted a trial to investigate the impact of conditional financial incentives and a decision support application, called EPIC-HIV, on HIV testing and linkage to care. We report the findings of the trial process evaluation to explore whether the interventions were delivered as intended, identify mechanisms of impact and any contextual factors that…
Looking for the future – Hope and adolescent risk behaviour in rural KwaZulu-Natal, South Africa
We investigate the relationship between hope and risky behaviour and the role of migration among young people in northern KwaZulu-Natal, South Africa. We use data from a cohort of n = 5248 adolescents and young adults (AYA) aged 13-35 recruited and followed up in 2017-2019. We conducted a structured quantitative survey to assess levels of hope among AYA using a validated tool/scale. 44% of participants were aged 13-17 years, 63% were still in sch…
Effect of a Male-Targeted Digital Decision Support Application Aimed at Increasing Linkage to HIV Care Among Men
Incident pregnancy and mental health among adolescent girls and young women in rural KwaZulu-Natal, South Africa
Pregnancy can place adolescent girls and young women (AGYW) at risk of poor mental health. However, evidence linking youth pregnancy to mental health in resource-limited settings is limited, especially where HIV incidence is high. We analysed a population-representative cohort of AGYW aged 13-25 in rural KwaZulu-Natal to assess how adolescent pregnancy predicts subsequent mental health. Among 1851 respondents, incident pregnancy (self-reported pa…
The effect of multi-level HIV prevention interventions on common mental disorders among adolescents and young adults in rural South Africa
This study evaluated the effect of multi-level HIV prevention interventions delivered through DREAMS (Determined, Resilient, Empowered, AIDS-free, Motivated, and Safe) program on common mental disorders (CMD) among adolescents and young adults (AYA) in rural South Africa. We used longitudinal data from two cohorts of AYA aged 13–35 years (N = 2184 for cohort 1 and N = 3067 for cohort 2), recruited between May 2017 and December 2018, with data col…
Understanding the mental health of adolescents and young adults in rural South Africa through participatory research
Most mental health problems in adulthood begin during adolescence. Factors such as poverty, violence, and unemployment contribute to the high burden of mental health problems. In Africa, the lack of resources for diagnosis, treatment, and management exacerbates the situation. Research on adolescent mental health has mostly focused on negative psychological effects, while positive attributes like coping, resilience, and emotional growth have been …
Challenges and opportunities in achieving sustainable development goal 3 in KwaZulu-Natal
South Africa is committed to achieving Sustainable Development Goal 3 (SDG 3), which aims to ensure health and well-being for all. However, in rural provinces like KwaZulu-Natal, structural inequalities, socio-cultural challenges, and environmental stressors hinder progress. This study synthesises findings from qualitative research conducted at the Africa Health Research Institute (AHRI) to explore the challenges and opportunities in meeting SDG …
Adolescent Sexual and Reproductive Health (24 obras) · HIV/AIDS Research and Interventions (21 obras) · Medicine (20 obras) · Psychology (15 obras) · Environmental health (13 obras) · Nursing (13 obras) · Family medicine (12 obras) · Psychological intervention (12 obras) · Public health (12 obras) · Sociology (10 obras)