Kirkby D Tickell

Datos Biográficos

ID7000255
NOMBREKirkby D Tickell
NOMBRESKirkby D
APELLIDOTickell
FIRMATICKELL K D
AFILIACIONESUniversity of Washington
ORCID0000-0002-4108-1236
VERIFICADOSí
TOTAL DE OBRAS7
TOTAL DE CITAS0
TOTAL COMO AUTOR7
TOTAL COMO EDITOR0
PRIMER AÑO DE PUBLICACIÓN2023
AÑO MÁS RECIENTE DE PUBLICACIÓN2026
ÍNDICE H0

  • Enteric dysfunction and enteropathogens among hospitalized south Asian and sub-Saharan African children

    Open AccessAbu Sadat Mohammad Sayeem Bin Shahid, Donna M Denno et al.ARTICLEPLOS Global Public Health2026

    Enteropathogens and enteric dysfunction (ED) among acutely ill children in low-and-middle income countries (LMICs) may contribute to poor post-discharge outcomes. Enteropathogen prevalence and fecal ED biomarkers (myeloperoxidase, calprotectin, α-1-antitrypsin) from children aged 2–23 months hospitalized at nine LMIC facilities (n = 811) were compared to community children (n = 248). Host and pathogen correlates of ED biomarkers were identified t…

  • Effect of azithromycin on post-discharge growth in Kenyan children

    Open AccessHannah E Atlas, Polycarp Mogeni et al.ARTICLEBMJ Global Health2025

    INTRODUCTION: Children discharged following hospitalisation for acute illnesses in low- and middle-income settings are at increased risk of poor growth, particularly linear growth faltering. We aimed to determine the effect of azithromycin administered at hospital discharge on post-discharge growth. METHODS: Using data from the Toto Bora Trial (NCT02414399), a double-blind, placebo-controlled randomised trial of a 5-day course of azithromycin in …

  • Aflatoxin exposure and mortality in acutely ill children

    Open AccessLei Xia, Hang Wu et al.ARTICLEBMJ Global Health2025

    BACKGROUND: Chronic exposure to aflatoxins is associated with liver cancer, impaired child growth, and compromised immune function. The Childhood Acute Illness and Nutrition (CHAIN) Network cohort was established to identify risk factors for mortality in acutely ill children admitted to nine hospitals in four African and two South Asian countries. We examined the role of aflatoxin exposure in inpatient and post-discharge mortality. METHODS: In a …

  • The diagnosis and management of dehydration in children with wasting or nutritional edema

    Open AccessAdino Tesfahun Tsegaye, Patricia B Pavlinac et al.ARTICLEPLOS Global Public Health2023

    Dehydration is a major cause of death among children with wasting and diarrhea. We reviewed the evidence for the identification and management of dehydration among these children. Two systematic reviews were conducted to assess 1) the diagnostic performance of clinical signs or algorithms intended to measure dehydration, and 2) the efficacy and safety of low-osmolarity ORS versus ReSoMal on mortality, treatment failure, time to full rehydration, …

  • Clinical epidemiology of Covid-19 among hospitalized children in rural western Kenya

    Open AccessAdino Tesfahun Tsegaye, Christina Sherry et al.ARTICLEPLOS Global Public Health2023

    The epidemiology of pediatric COVID-19 in sub-Saharan Africa and the role of fecal-oral transmission in SARS-CoV-2 are poorly understood. Among children and adolescents in Kenya, we identify correlates of COVID-19 infection, document the clinical outcomes of infection, and evaluate the prevalence and viability of SARS-CoV-2 in stool. We recruited a prospective cohort of hospitalized children aged two months to 15 years in western Kenya between Ma…

  • Considering Risks to Researchers and Staff in Low-Resource Settings during Public Health Crises

    Open AccessKrystle Perez, Muhammad Asim et al.ARTICLEChildren2023

    Human subjects research protections have historically focused on mitigating risk of harm and promoting benefits for research participants. In many low-resource settings (LRS), complex and often severe challenges in daily living, poverty, geopolitical uprisings, sociopolitical, economic, and climate crises increase the burdens of even minimal risk research. While there has been important work to explore the scope of ethical responsibilities of res…

  • Minimizing error in estimates of the effect of interventions by accounting for baseline measurements

    Open AccessE Deichsel, Emily L Deichsel et al.ARTICLEMaternal and Child Nutrition2023

    Interventions to reduce childhood stunting burden require clinical trials with a primary outcome of linear growth. When growth is measured longitudinally, there are several options for including baseline measurements in the analysis. This study compares the performance of several methods. Randomized controlled trials evaluating a hypothetical intervention to improve length-for-age z-score (LAZ) from birth through 24 months of age were simulated. …