Frank Cobelens

Datos Biográficos

ID7001836
NOMBREFrank Cobelens
NOMBRESFrank
APELLIDOCobelens
FIRMACOBELENS F
AFILIACIONESAmsterdam UMC Location University of Amsterdam
ORCID0000-0002-4367-1133
VERIFICADOSí
TOTAL DE OBRAS12
TOTAL DE CITAS0
TOTAL COMO AUTOR12
TOTAL COMO EDITOR0
PRIMER AÑO DE PUBLICACIÓN2007
AÑO MÁS RECIENTE DE PUBLICACIÓN2026
ÍNDICE H0

  • Association of Human Cytomegalovirus exposure with tuberculosis disease in South African adults with presumptive tuberculosis

    Open AccessDerrick Semugenze, Arthur Chiwaya et al.ARTICLEPLOS Global Public Health2026

    Recent studies suggested that human cytomegalovirus (HCMV) exposure may increase tuberculosis (TB) disease risk. We assessed the association between active HCMV infection and recent HCMV exposure with tuberculosis (TB) disease among TB-presumptive South African adults. This was a cross-sectional case-control study that utilized stored plasma and serum samples collected from adults (≥18 years) with presumptive TB self-presenting to primary care cl…

  • Potential impact, costs, and benefits of population-wide screening interventions for tuberculosis in Viet Nam

    Open AccessAlvaro Schwalb, Katherine C Horton et al.ARTICLEPLOS Global Public Health2025

    Population-wide screening may accelerate the decline of tuberculosis (TB) incidence, but the optimal screening algorithm and duration must weigh resource considerations. We calibrated a deterministic transmission model to TB epidemiology in Viet Nam. We simulated three population-wide screening algorithms from 2025: sputum nucleic acid amplification tests (NAAT, Xpert MTB/RIF Ultra) only; chest radiography (CXR) followed by NAAT; and CXR-only wit…

  • Transferable data exclusivity vouchers are not the solution to the antimicrobial drug development crisis

    Open AccessAstrid Berner-Rodoreda, Frank Cobelens et al.ARTICLEBMJ Global Health2024

    Access to pharmaceutical products worsened during the COVID-19 pandemic when key developers of active pharmaceutical ingredients and medicinal products prioritised their national markets. These challenges led to a stronger commitment by the European Union (EU) to become more autonomous in developing and providing access to pharmaceutical products for its population.1 In April 2023, the European Commission (EC) proposed a reform of the EU pharma r…

  • Active contact tracing beyond the household in multidrug resistant tuberculosis in Vietnam

    Open AccessHoàng Thị Thanh Thủy, Thi Thanh Thuy Hoang et al.ARTICLEBMC Public Health2019

    No new MDR-TB cases were detected using social network analysis of nearly 100 MDR-TB index cases, likely due to a relatively short follow up time, and loss to follow up (lack of cooperation from contacts or high risk places and lack of available resources in the National Tuberculosis Control Programme)

  • Challenges in detection and treatment of multidrug resistant tuberculosis patients in Vietnam

    Open AccessHoàng Thị Thanh Thủy, Thuy Thi Thanh Hoang et al.ARTICLEBMC Public Health2015

    The proportion of MDR-TB patients diagnosed and enrolled for second-line treatment is less than 20 % of the estimated total. The low enrollment is largely due to the fact that many patients at risk are missed for MDR-TB screening. In order to detect more MDR-TB cases, Vietnam should intensify case finding of MDR-TB by a comprehensive strategy to screen for MDR-TB among new cases rather than targeting previously treated cases, in particular those …

  • A household survey on screening practices of household contacts of smear positive tuberculosis patients in Vietnam

    Open AccessThuy Hoang Thi Thanh, Sy Dinh Ngoc et al.ARTICLEBMC Public Health2014

    The low proportion of household TB contacts screened for TB illustrates the limitations of passive contact screening as currently practiced in Vietnam. Children under 5 years of age are particularly neglected with this approach. Active contact screening with fixed follow-up times of close contacts of newly diagnosed TB patients should be considered in Vietnam, particularly in case of young children and drug-resistant TB

  • Effect of changing antiretroviral treatment eligibility criteria on patient load in Kampala, Uganda

    Joseph Konde-Lule, Fred Makumbi et al.ARTICLEAIDS Care2011

    In many resource-poor countries, CD4 count thresholds of eligibility for antiretroviral treatment (ART) were initially low (<200 cells/mm(3)) but are now being increased to improve patient survival and to reduce HIV transmission. There are few quantitative data on the effect of such increases on the demand for ART. The objective of this study was to measure HIV prevalence and the proportion of HIV-positives eligible for antiretroviral therapy at …

  • Low HIV testing rates among tuberculosis patients in Kampala, Uganda

    Open AccessIbrahim Sendagire, Imke Schreuder et al.ARTICLEBMC Public Health2010

    The overall HIV test uptake was surprisingly low at 40%. The HIV test uptake was significantly higher among TB patients who were identified at hospital, among females and in the unemployed

  • Implementation of a national anti-tuberculosis drug resistance survey in Tanzania

    Open AccessTimothy M Chonde, Basra Doulla et al.ARTICLEBMC Public Health2008

    Careful preparation of the survey, timing of planned activities, a strong emphasis on data capture tools and data management, and timely supervision are essential for a proper implementation of a national drug resistance survey

  • Delays in the diagnosis and treatment of tuberculosis patients in Vietnam

    Open AccessNguyen T Huong, Marleen Vree et al.ARTICLEBMC Public Health2007

    Analyses of patient and treatment delays can indicate target groups and areas for health education and strengthening of the referral system, in particular between the private sector and the NTP

  • Mortality and failure among tuberculosis patients who did not complete treatment in Vietnam

    Open AccessMarleen Vree, Nguyen T Huong et al.ARTICLEBMC Public Health2007

    The total failure and death rates are 0.6% and 0.8% higher than based on routine reporting in northern Vietnam. Although this was a large proportion of treatment failures and deaths, failure and death rates were low. Defaulting and transfer carry a high risk of failure and in particular death

  • High mortality during tuberculosis treatment does not indicate long diagnostic delays in Vietnam

    Open AccessMarleen Vree, Nguyen T Huong et al.ARTICLEBMC Public Health2007

    Diagnostic delay is not associated with treatment mortality in Vietnam at individual nor district level, suggesting that high case fatality should not be used as an indicator of long diagnostic delay in national tuberculosis programmes