David S Lawrence
Datos Biográficos
| ID | 709363 |
|---|---|
| NOMBRE | David S Lawrence |
| NOMBRES | David S |
| APELLIDO | Lawrence |
| FIRMA | LAWRENCE D S |
| AFILIACIONES | University Hospitals Sussex NHS Foundation Trust |
| ORCID | 0000-0002-5439-4039 |
| VERIFICADO | Sí |
| TOTAL DE OBRAS | 6 |
| TOTAL DE CITAS | 1 |
| TOTAL COMO AUTOR | 6 |
| TOTAL COMO EDITOR | 0 |
| PRIMER AÑO DE PUBLICACIÓN | 1971 |
| AÑO MÁS RECIENTE DE PUBLICACIÓN | 2026 |
| ÍNDICE H | 1 |
How the multiple burdens of daily oral antiretroviral therapy shape the acceptability of long-acting injectable cabotegravir and rilpivirine among people living with HIV in Uganda and South Africa
Long-acting injectable antiretroviral therapy (LAI-ART) has the potential to improve adherence and treatment outcomes among people living with HIV (PLHIV) who experience challenges with adherence to oral medication. We explored how experiences with daily oral ART shaped LAI-ART acceptability within a clinical trial in Uganda and South Africa. A qualitative methods sub-study was nested within a phase 3b randomised clinical trial evaluating long-ac…
Pathways to care with HIV-associated cryptococcal meningitis in Botswana and Uganda
HIV-associated cryptococcal meningitis remains a key driver of AIDS-related mortality. Mortality is twice as high in those who present later to care and with severe symptoms such as confusion. We embedded a qualitative methods study within a randomised controlled trial in Gaborone, Botswana and Kampala, Uganda with the aim of understanding pathways to care. We conducted in-depth interviews with trial participants and surrogate decision makers and…
Decision making in a clinical trial for a life-threatening illness
Potential participants for clinical trials which aim to define treatments for life-threatening conditions are often extremely unwell. When exploring why individuals participate in clinical trials one common observation is a misplaced expectation of personal benefit - a therapeutic misconception. The care offered in some clinical trials is of a higher standard than is routinely available and this has led to criticism around the freedom of choice t…
The UK Foundation Programme for newly qualified doctors
Introduction: After completing a five year undergraduate degree, all newly qualified doctors in the United Kingdom undertake a two-year Foundation Programme which aims to provide them with the necessary experience, supervision and guidance to prepare them for a career in clinical medicine. Foundation Doctors are paid members of the team and undertake a variety of clinical rotations with supervision from senior colleagues, a process that is regula…
International advisory board
Protein phosphorylation is widely recognized as the most important pathway of regulation of protein functions in living cells, by switching cellular activities from one state to another, and regulating gene expression, cell proliferation and cell differentiation. It is the major mechanism by which cells respond to extracellular signals such as hormones and growth factors, and controls all events at various stages of the cell cycle. Reversible pro…
The Initial Decision to Build the Supersonic Transport
Decision making in a clinical trial for a life-threatening illness
Potential participants for clinical trials which aim to define treatments for life-threatening conditions are often extremely unwell. When exploring why individuals participate in clinical trials one common observation is a misplaced expectation of personal benefit - a therapeutic misconception. The care offered in some clinical trials is of a higher standard than is routinely available and this has led to criticism around the freedom of choice t…
The Initial Decision to Build the Supersonic Transport
International advisory board
Protein phosphorylation is widely recognized as the most important pathway of regulation of protein functions in living cells, by switching cellular activities from one state to another, and regulating gene expression, cell proliferation and cell differentiation. It is the major mechanism by which cells respond to extracellular signals such as hormones and growth factors, and controls all events at various stages of the cell cycle. Reversible pro…
The UK Foundation Programme for newly qualified doctors
Introduction: After completing a five year undergraduate degree, all newly qualified doctors in the United Kingdom undertake a two-year Foundation Programme which aims to provide them with the necessary experience, supervision and guidance to prepare them for a career in clinical medicine. Foundation Doctors are paid members of the team and undertake a variety of clinical rotations with supervision from senior colleagues, a process that is regula…
Decision making in a clinical trial for a life-threatening illness
Potential participants for clinical trials which aim to define treatments for life-threatening conditions are often extremely unwell. When exploring why individuals participate in clinical trials one common observation is a misplaced expectation of personal benefit - a therapeutic misconception. The care offered in some clinical trials is of a higher standard than is routinely available and this has led to criticism around the freedom of choice t…
Pathways to care with HIV-associated cryptococcal meningitis in Botswana and Uganda
HIV-associated cryptococcal meningitis remains a key driver of AIDS-related mortality. Mortality is twice as high in those who present later to care and with severe symptoms such as confusion. We embedded a qualitative methods study within a randomised controlled trial in Gaborone, Botswana and Kampala, Uganda with the aim of understanding pathways to care. We conducted in-depth interviews with trial participants and surrogate decision makers and…
How the multiple burdens of daily oral antiretroviral therapy shape the acceptability of long-acting injectable cabotegravir and rilpivirine among people living with HIV in Uganda and South Africa
Long-acting injectable antiretroviral therapy (LAI-ART) has the potential to improve adherence and treatment outcomes among people living with HIV (PLHIV) who experience challenges with adherence to oral medication. We explored how experiences with daily oral ART shaped LAI-ART acceptability within a clinical trial in Uganda and South Africa. A qualitative methods sub-study was nested within a phase 3b randomised clinical trial evaluating long-ac…
Medicine (3 obras) · Qualitative research (3 obras) · Clinical trial (2 obras) · Family medicine (2 obras) · Health care (2 obras) · Nursing (2 obras) · Political science (2 obras) · Psychiatry (2 obras) · Air Traffic Management and Optimization (1 obras) · Alternative medicine (1 obras)