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Hiroshi Odaguchi

Datos Biográficos

ID7284151
NOMBREHiroshi Odaguchi
NOMBRESHiroshi
APELLIDOOdaguchi
FIRMAODAGUCHI H
AFILIACIONESKitasato Institute Hospital
ORCID0000-0002-8863-1557
VERIFICADOSí
TOTAL DE OBRAS2
TOTAL DE CITAS0
TOTAL COMO AUTOR2
TOTAL COMO EDITOR0
PRIMER AÑO DE PUBLICACIÓN2023
AÑO MÁS RECIENTE DE PUBLICACIÓN2024
ÍNDICE H0
  • Intron retention as an excellent marker for diagnosing depression and for discovering new potential pathways for drug intervention

    Open Access•Norihiro Okada, Kenshiro Oshima et al.•ARTICLE•Frontiers in Psychiatry•2024

    Depression was found to be associated with activation of the innate immune response and relative inactivation of T-cell signaling. The DEGs we identified reflect physiological demands that are controlled at the transcriptional level, whereas the IR results reflect a more direct mechanism for monitoring protein homeostasis. Accordingly, an alteration in IR, namely IncIR or DecIR, is a stress response, and intron-retained transcripts are sensors of…

  • Overlooked switch from transient sedation to sustained excitement in the Biphasic effects of Ephedra Herb extract administered orally to mice

    Open Access•Xuedan Huang, Sumiko Hyuga et al.•ARTICLE•Journal of Ethnopharmacology•2023

    We discovered for the first time that EHE evokes diphasic action by switching from transient sedation to sustained excitement. The transient sedation was evoked by the Eph and Pse in the herbal extract via activation of the α2a adrenoceptor and the sustained excitement was caused by the Eph in the herbal extract

Sin obras prominentes en esta página.

  • Overlooked switch from transient sedation to sustained excitement in the Biphasic effects of Ephedra Herb extract administered orally to mice

    Open Access•Xuedan Huang, Sumiko Hyuga et al.•ARTICLE•Journal of Ethnopharmacology•2023

    We discovered for the first time that EHE evokes diphasic action by switching from transient sedation to sustained excitement. The transient sedation was evoked by the Eph and Pse in the herbal extract via activation of the α2a adrenoceptor and the sustained excitement was caused by the Eph in the herbal extract

  • Intron retention as an excellent marker for diagnosing depression and for discovering new potential pathways for drug intervention

    Open Access•Norihiro Okada, Kenshiro Oshima et al.•ARTICLE•Frontiers in Psychiatry•2024

    Depression was found to be associated with activation of the innate immune response and relative inactivation of T-cell signaling. The DEGs we identified reflect physiological demands that are controlled at the transcriptional level, whereas the IR results reflect a more direct mechanism for monitoring protein homeostasis. Accordingly, an alteration in IR, namely IncIR or DecIR, is a stress response, and intron-retained transcripts are sensors of…

Anesthesia (1 obras) · Antidepressant (1 obras) · Behavioural despair test (1 obras) · Biology (1 obras) · Chemical synthesis and alkaloids (1 obras) · Depression (economics (1 obras) · Ephedrine (1 obras) · Gene (1 obras) · Genetics (1 obras) · Herb (1 obras)

Ethnos_APP • Proyecto Open Source • Licencia MIT • Frontend v2.0.0 • Privacidad y Cookies • Documentación de la API: api.ethnos.app/docs • Código de la API: GitHub • DOI: 10.5281/zenodo.17049435 • Código del Frontend: GitHub • DOI: 10.5281/zenodo.17050053 • cruz.rio.br • Expectantes Misericordiae