Zhiren Wang
Datos Biográficos
| ID | 7532709 |
|---|---|
| NOMBRE | Zhiren Wang |
| NOMBRES | Zhiren |
| APELLIDO | Wang |
| FIRMA | WANG Z |
| AFILIACIONES | Peking University |
| ORCID | 0000-0002-8679-9495 |
| VERIFICADO | Sí |
| TOTAL DE OBRAS | 14 |
| TOTAL DE CITAS | 0 |
| TOTAL COMO AUTOR | 14 |
| TOTAL COMO EDITOR | 0 |
| PRIMER AÑO DE PUBLICACIÓN | 2020 |
| AÑO MÁS RECIENTE DE PUBLICACIÓN | 2026 |
| ÍNDICE H | 0 |
Development of a Brief Computerized Adaptive Testing Version of the SCL-90
The Symptom Checklist-90 (SCL-90) is widely used in Chinese adolescents, but its practical utility is limited by its length and by structural problems in the traditional ten-factor model. To address these issues, this study developed and validated a brief computerized adaptive testing (CAT) system based on a theoretically informed six-factor model. Using a clinical sample of 10,052 adolescent outpatients, confirmatory factor analysis showed the t…
Obesity, cytokines and psychopathology in patients with chronic schizophrenia
Higher BMI in chronic schizophrenia is associated with reduced IL-2 levels, attenuated negative symptoms, and adverse lipid profiles. TNF-α may modulate psychopathology severity. These findings highlight complex interactions between metabolic dysregulation, immune markers, and clinical manifestations in schizophrenia
Phenome-wide association studies between Serinc2 and neuropsychiatric disorders
SERINC2 is primarily linked to substance use disorders, schizophrenia, OCD, autism and bipolar disorder, not only statistically but also biologically
Alcohol drinking in male patients with chronic schizophrenia
These findings suggest that alcohol use is common during the lifetime of SCZ patients and that alcohol use may be associated with clinical symptoms in SCZ patients
Associations of the serum kynurenine pathway metabolites with P50 auditory gating in non-smoking patients with first-episode schizophrenia
Our findings suggested that neuroactive metabolites of the KP might play an important role in sensory gating deficit in first episode patients with schizophrenia. Furthermore, metabolites of the KP may be a new target for the treatment of cognitive impairments in schizophrenia
The relationship between TLR4/NF-κB/IL-1β signaling, cognitive impairment, and white-matter integrity in patients with stable chronic schizophrenia
Our findings support altered TLR4 signaling pathway activity in association with deficits in cognition and white matter integrity in schizophrenia
Relationship Between Plasma Olanzapine and N-Desmethyl-Olanzapine Concentration and Metabolic Parameters in Patients With Schizophrenia
These results demonstrate that OLA and its metabolite DMO may have different effects on OLA-induced metabolic abnormalities. DMO might have a counteracting effects on glucose-insulin homeostasis and lipid metabolic abnormalities, which suggests that regular measure of various metabolic parameters and drug monitoring on both OLA and DMO are recommended in OLA-treated patients with schizophrenia
Vocal Acoustic Features as Potential Biomarkers for Identifying/Diagnosing Depression
The acoustic expression of emotion among patients with depression differs from that of normal controls. Some acoustic characteristics are related to the severity of depressive symptoms and may be objective biomarkers of depression. A systematic method of assessing vocal acoustic characteristics could provide an accurate and discreet means of screening for depression; this method may be used instead of-or in conjunction with-traditional screening …
Pathways from self-disclosure to medical coping strategy among adolescents with moderate and major depression during the Covid-19 pandemic
Self-efficacy played a partial mediating role in the effect of self-disclosure on medical coping strategies for adolescent depression during the COVID-19 pandemic, and the use of a positive self-disclosure mechanism may be anticipated to promote improved self-efficacy and the use of active coping strategies
Subcortical Brain Volumes Relate to Neurocognition in First-Episode Schizophrenia, Bipolar Disorder, Major Depression Disorder, and Healthy Controls
The different degrees of subcortical volume lessening may contribute to the differences in cognitive impairment among the three psychiatric disorders
High-Dose Betahistine Improves Cognitive Function in Patients With Schizophrenia
Background: There is currently no effective treatment for cognitive impairment associated with schizophrenia (CIAS). Recent studies have shown that increased histamine levels in the brain may help to improve CIAS symptoms. Betahistine is an H1-receptor agonist and H3-receptor antagonist. This study evaluated the effect of high-dose betahistine on cognitive function as well as its safety in Chinese Han patients with schizophrenia. Methods: This ra…
Impaired Emotional Self-Referential Processing in First-Episode Schizophrenia
Impairments in self-representation are relevant to the expression of psychosis. To date, the characteristics and neural mechanisms of self-impairment in schizophrenia remain unclear. To this end, we used event-related potentials (ERPs) to measure brain activity in 56 first-episode patients with schizophrenia and 56 healthy controls. Participants judged personal trait adjectives regarding themselves, their mothers, or a public person, followed by …
Gut Microbiome Composition Associated With Major Depressive Disorder and Sleep Quality
The microbiota-gut-brain axis plays a critical role in the pathogenesis of major depressive disorder (MDD) and related subclinical symptoms. However, studies on the gut microbiota in MDD are inconsistent, and data on MDD's effects on sleep are lacking. This study aimed to analyze the gut microbiota composition and sleep quality of patients with MDD. We performed 16S rRNA sequencing of stool samples from 36 patients with MDD and 45 healthy control…
Cortical Thickness in Alcohol Dependent Patients With Apathy
The current results suggest the thickness of bilateral parietal and occipital temporal cortices as neural markers of apathy in PADs. These findings add to the literature by identifying the neural bases of a critical clinical feature of individuals with alcoholism
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Cortical Thickness in Alcohol Dependent Patients With Apathy
The current results suggest the thickness of bilateral parietal and occipital temporal cortices as neural markers of apathy in PADs. These findings add to the literature by identifying the neural bases of a critical clinical feature of individuals with alcoholism
High-Dose Betahistine Improves Cognitive Function in Patients With Schizophrenia
Background: There is currently no effective treatment for cognitive impairment associated with schizophrenia (CIAS). Recent studies have shown that increased histamine levels in the brain may help to improve CIAS symptoms. Betahistine is an H1-receptor agonist and H3-receptor antagonist. This study evaluated the effect of high-dose betahistine on cognitive function as well as its safety in Chinese Han patients with schizophrenia. Methods: This ra…
Impaired Emotional Self-Referential Processing in First-Episode Schizophrenia
Impairments in self-representation are relevant to the expression of psychosis. To date, the characteristics and neural mechanisms of self-impairment in schizophrenia remain unclear. To this end, we used event-related potentials (ERPs) to measure brain activity in 56 first-episode patients with schizophrenia and 56 healthy controls. Participants judged personal trait adjectives regarding themselves, their mothers, or a public person, followed by …
Gut Microbiome Composition Associated With Major Depressive Disorder and Sleep Quality
The microbiota-gut-brain axis plays a critical role in the pathogenesis of major depressive disorder (MDD) and related subclinical symptoms. However, studies on the gut microbiota in MDD are inconsistent, and data on MDD's effects on sleep are lacking. This study aimed to analyze the gut microbiota composition and sleep quality of patients with MDD. We performed 16S rRNA sequencing of stool samples from 36 patients with MDD and 45 healthy control…
Associations of the serum kynurenine pathway metabolites with P50 auditory gating in non-smoking patients with first-episode schizophrenia
Our findings suggested that neuroactive metabolites of the KP might play an important role in sensory gating deficit in first episode patients with schizophrenia. Furthermore, metabolites of the KP may be a new target for the treatment of cognitive impairments in schizophrenia
The relationship between TLR4/NF-κB/IL-1β signaling, cognitive impairment, and white-matter integrity in patients with stable chronic schizophrenia
Our findings support altered TLR4 signaling pathway activity in association with deficits in cognition and white matter integrity in schizophrenia
Relationship Between Plasma Olanzapine and N-Desmethyl-Olanzapine Concentration and Metabolic Parameters in Patients With Schizophrenia
These results demonstrate that OLA and its metabolite DMO may have different effects on OLA-induced metabolic abnormalities. DMO might have a counteracting effects on glucose-insulin homeostasis and lipid metabolic abnormalities, which suggests that regular measure of various metabolic parameters and drug monitoring on both OLA and DMO are recommended in OLA-treated patients with schizophrenia
Vocal Acoustic Features as Potential Biomarkers for Identifying/Diagnosing Depression
The acoustic expression of emotion among patients with depression differs from that of normal controls. Some acoustic characteristics are related to the severity of depressive symptoms and may be objective biomarkers of depression. A systematic method of assessing vocal acoustic characteristics could provide an accurate and discreet means of screening for depression; this method may be used instead of-or in conjunction with-traditional screening …
Pathways from self-disclosure to medical coping strategy among adolescents with moderate and major depression during the Covid-19 pandemic
Self-efficacy played a partial mediating role in the effect of self-disclosure on medical coping strategies for adolescent depression during the COVID-19 pandemic, and the use of a positive self-disclosure mechanism may be anticipated to promote improved self-efficacy and the use of active coping strategies
Subcortical Brain Volumes Relate to Neurocognition in First-Episode Schizophrenia, Bipolar Disorder, Major Depression Disorder, and Healthy Controls
The different degrees of subcortical volume lessening may contribute to the differences in cognitive impairment among the three psychiatric disorders
Alcohol drinking in male patients with chronic schizophrenia
These findings suggest that alcohol use is common during the lifetime of SCZ patients and that alcohol use may be associated with clinical symptoms in SCZ patients
Obesity, cytokines and psychopathology in patients with chronic schizophrenia
Higher BMI in chronic schizophrenia is associated with reduced IL-2 levels, attenuated negative symptoms, and adverse lipid profiles. TNF-α may modulate psychopathology severity. These findings highlight complex interactions between metabolic dysregulation, immune markers, and clinical manifestations in schizophrenia
Phenome-wide association studies between Serinc2 and neuropsychiatric disorders
SERINC2 is primarily linked to substance use disorders, schizophrenia, OCD, autism and bipolar disorder, not only statistically but also biologically
Development of a Brief Computerized Adaptive Testing Version of the SCL-90
The Symptom Checklist-90 (SCL-90) is widely used in Chinese adolescents, but its practical utility is limited by its length and by structural problems in the traditional ten-factor model. To address these issues, this study developed and validated a brief computerized adaptive testing (CAT) system based on a theoretically informed six-factor model. Using a clinical sample of 10,052 adolescent outpatients, confirmatory factor analysis showed the t…
Medicine (12 obras) · Psychiatry (12 obras) · Internal Medicine (10 obras) · Psychology (9 obras) · Schizophrenia (object-oriented programming (9 obras) · Schizophrenia research and treatment (7 obras) · Clinical Psychology (5 obras) · Clinical Psychology (5 obras) · Cognition (5 obras) · Tryptophan and brain disorders (5 obras)