Mark P Nicol

Datos Biográficos

ID7581326
NOMBREMark P Nicol
NOMBRESMark P
APELLIDONicol
FIRMANICOL M P
AFILIACIONESUniversity of Cape Town
ORCID0000-0002-1366-4805
VERIFICADOSí
TOTAL DE OBRAS7
TOTAL DE CITAS0
TOTAL COMO AUTOR7
TOTAL COMO EDITOR0
PRIMER AÑO DE PUBLICACIÓN2009
AÑO MÁS RECIENTE DE PUBLICACIÓN2024
ÍNDICE H0

  • Risk and rates of hospitalisation in young children

    Open AccessCatherine J Wedderburn, Julia Bondar et al.ARTICLEPLOS Global Public Health2024

    Children in sub-Saharan Africa (SSA) are disproportionately affected by morbidity and mortality. There is also a growing vulnerable population of children who are HIV-exposed uninfected (HEU). Understanding reasons and risk factors for early-life child hospitalisation will help optimise interventions to improve health outcomes. We investigated hospitalisations from birth to two years in a South African birth cohort study. Mother-child pairs in th…

  • Global, regional, and national disease burden estimates of acute lower respiratory infections due to respiratory syncytial virus in children younger than 5 years in 2019

    Open AccessYou Li, Xin Wang et al.ARTICLEThe Lancet2022

    BACKGROUND: Respiratory syncytial virus (RSV) is the most common cause of acute lower respiratory infection in young children. We previously estimated that in 2015, 33·1 million episodes of RSV-associated acute lower respiratory infection occurred in children aged 0-60 months, resulting in a total of 118 200 deaths worldwide. Since then, several community surveillance studies have been done to obtain a more precise estimation of RSV associated co…

  • The role of emergent champions in policy implementation for decentralised drug-resistant tuberculosis care in South Africa

    Open AccessSacha Roxanne Le Roux, Waasila Jassat et al.ARTICLEBMJ Global Health2022

    OBJECTIVE: Champions are recognised as important to driving organisational change in healthcare quality improvement initiatives in high-income settings. In low-income and middle-income countries with a high disease burden and constrained human resources, their role is highly relevant yet understudied. Within a broader study on policy implementation for decentralised drug-resistant tuberculosis care in South Africa, we characterised the role, stra…

  • We had to manage what we had on hand, in whatever way we could’

    Open AccessKarina Kielmann, Lindy Dickson-Hall et al.ARTICLEHealth Policy and Planning2021

    In 2011, the South African National TB Programme launched a policy of decentralized management of drug-resistant tuberculosis (DR-TB) in order to expand the capacity of facilities to treat patients with DR-TB, minimize delays to access care and improve patient outcomes. This policy directive was implemented to varying degrees within a rapidly evolving diagnostic and treatment landscape for DR-TB, placing new demands on already-stressed health sys…

  • Characterization of Pneumococcal Colonization Dynamics and Antimicrobial Resistance Using Shotgun Metagenomic Sequencing in Intensively Sampled South African Infants

    Open AccessRendani I Manenzhe, Felix S Dube et al.ARTICLEFrontiers in Public Health2020

    There remains a significant proportion of deaths due to pneumococcal pneumonia in infants from low- and middle-income countries despite the marginal global declines recorded in the past decade. Monitoring changes in pneumococcal carriage is key to understanding vaccination-induced shifts in the ecology of carriage, patterns of antimicrobial resistance, and impact on health. We longitudinally investigated pneumococcal carriage dynamics in PCV-13 v…

  • A very humiliating illness”

    Open AccessJennifer Furin, Marian Loveday et al.ARTICLEBMC Public Health2020

    Beyond being a "very humiliating illness", RR-TB robs people of their physical, social, economic, psychological, and emotional well-being far beyond the period when treatment is being administered. Efforts to tackle these issues are as important as new drugs and diagnostics in the fight against TB

  • High levels of multidrug resistant tuberculosis in new and treatment-failure patients from the Revised National Tuberculosis Control Programme in an urban metropolis (Mumbai) in Western India

    Open AccessDesiree T B D'souza, Desiree TB D'souza et al.ARTICLEBMC Public Health2009

    Levels of MDRTB are much higher in both previously untreated and first line treatment-failure cases in the selected wards in Mumbai than those projected by national estimates. The finding of amplified drug resistance suggests the presence of a well entrenched MDRTB scenario. This study suggests that a wider set of surveillance sites are needed to obtain a more realistic view of the true MDRTB rates throughout the country. This would assist in the…