Jayne Lewis-Kulzer
Datos Biográficos
| ID | 7727626 |
|---|---|
| NOMBRE | Jayne Lewis-Kulzer |
| NOMBRES | Jayne |
| APELLIDO | Lewis-Kulzer |
| FIRMA | LEWIS-KULZER J |
| AFILIACIONES | University of California, San Francisco |
| ORCID | 0000-0003-3314-9891 |
| VERIFICADO | Sí |
| TOTAL DE OBRAS | 21 |
| TOTAL DE CITAS | 0 |
| TOTAL COMO AUTOR | 21 |
| TOTAL COMO EDITOR | 0 |
| PRIMER AÑO DE PUBLICACIÓN | 2018 |
| AÑO MÁS RECIENTE DE PUBLICACIÓN | 2026 |
| ÍNDICE H | 0 |
Systematic dissemination of study findings from local to national stakeholders
Disseminating research findings to potential beneficiaries such as study participants, community members, and stakeholders is a critical component of participatory research. While there is general agreement that dissemination is critical, documented examples of comprehensive dissemination activities are few in the literature. We present a concrete example of a multi-level stakeholder dissemination process from a successful HIV self-testing and li…
Social relationships, mental health, and stigma
The disclosure of one’s HIV-positive status is a personal decision that can play an important role in engagement in HIV treatment and care. Social network approaches situate individuals within broader webs of social connections that influence health and wellbeing and thus hold the potential to elucidate key social factors shaping the process of disclosure. As part of a larger clinical study examining how substance use and mental health shape HIV …
HIVST in the presence of a partner among fishermen in Western Kenya
BACKGROUND: HIV self-testing (HIVST) enables individuals to test privately and can serve as an important tool to mitigate stigma and fear of HIV testing and unintended disclosure, especially among men, who have lower voluntary testing rates than women. AIM: Within an intervention study involving distribution of HIVST kits by fishermen to their peers [NCT04772469], we explore the experiences and the motivations of men who chose to self-test for HI…
Motivations for testing and linkage to HIV services following HIV self-testing among fishermen in Kenya
HIV self-testing (HIVST) is a promising strategy to expand testing access for hard-to-reach populations such as Kenyan fishermen. We examined motivations and barriers to HIVST use and linkage to HIV prevention and treatment services (including PrEP or ART), within a social network-based intervention (NCT04772469). We conducted interviews (N = 64) and focus group discussions (N = 4) with fishermen in Siaya County, including 30 “promoters” who dist…
“ I feel like a guest on the other side ”
Adolescents and young adults living with HIV (AYAH) face significant challenges when transitioning from adolescent to adult HIV services. Up to 50% of AYAH do not remain engaged in care after transition, which may result in virological failure. We sought to understand challenges to clinic transitions and youth-identified solutions to optimize health outcomes. We conducted three focus group discussions (FGDs) (n = 33) and a 4-day participatory, hu…
Hazardous alcohol use is associated with sexual behaviors that increase risk for HIV acquisition among fishermen in a high HIV prevalence area of Kenya
Links between hazardous alcohol use and HIV acquisition are well documented, with less known about this relationship among fishermen, a priority group for HIV prevention. We examined associations between hazardous alcohol use and sexual risk behaviors among fishermen in Kenya using 2022 data from 733 fishermen in three Lake Victoria communities. Measures included the AUDIT-C and sexual relationship histories. Logistic regression models assessed a…
Effectiveness and experiences with differentiated service delivery of HIV care in Kisumu County, Kenya
The adoption of the test and treat policy by the World Health Organization (WHO) in 2015 led to an unprecedented increase in the number of people living with HIV (PLHIV) enrolling into HIV treatment, thereby increasing the burden on HIV service delivery. To compensate, WHO endorsed the Differentiated Service Delivery (DSD) approach to reduce the burden on the health care system and therefore support attainment of the UNAIDS 95-95-95 goals by 2030…
Enhancing engagement in HIV care among adolescents and young adults
Structural, psychological, and clinical barriers to HIV care engagement among adolescents and young adults living with HIV (AYAH) persist globally despite gains in HIV epidemic control. Phone-based peer navigation may provide critical peer support, increase delivery flexibility, and require fewer resources. Prior studies show that phone-based navigation and automated text messaging interventions improve HIV care engagement, adherence, and retenti…
Examining and classifying reasons for missing viral loads among adults living with HIV
Gaps in HIV RNA monitoring persist globally impeding the ability to determine clinical progress and outcomes. This study systematically evaluated provider (e.g., guideline non-adherence), system (e.g., laboratory error) and participant-level (e.g., refusal) drivers of missed viral load (VL) monitoring measurements among people with HIV in Kenya. Adults aged 18–65 years were followed across five health facilities in Kenya as part of a clinical tri…
Misconceptions and limited experience with HIV pre-exposure prophylaxis (PrEP) among fishermen in Western Kenya
Daily oral HIV pre-exposure prophylaxis (PrEP) is highly effective when taken consistently, but its uptake remains low among mobile fishermen in Kenya. This study explored barriers and facilitators to PrEP uptake in three Lake Victoria beach communities. In-depth interviews (IDIs) and focus group discussions (FGDs) were conducted with 65 fishermen, purposively sampled by community, age and study arm. IDIs and FGDs examined PrEP knowledge, percept…
Comparing PrEP adherence via objective and self-reported measures among fishermen working on Lake Victoria, Kenya
Fishermen working along Lake Victoria experience high rates of HIV acquisition that can be mitigated by pre-exposure prophylaxis (PrEP), which requires adequate adherence for effective prevention. We evaluated PrEP adherence among Kenyan fishermen using objective metrics and examine non-adherence. Data are from the Owete study (NCT04772469), a cluster randomized-controlled trial using a social network approach among fishermen to increase HIV test…
Experiences and perceptions of conditional cash incentive provision and cessation among people with HIV for care engagement
CCTs do not appear to exert their effects through motivation, but instead act through creating opportunities for better care engagement. This study helps us better understand the durability of financial incentives for HIV care engagement and support the idea that careful consideration be exercised when implementing incentives for sustainable engagement effects
There is no need to leave the beach to test”
While few fishermen had ever used HIVST, this study found high awareness, positive perceptions, and substantial willingness to use and distribute HIVST to other men. The "promoter" model, with known peers engaged in disseminating HIVST information and test kits, shows promise for engaging men in testing
Gaps in Effective HIV Pre-exposure Prophylaxis Screening and Uptake Among Fishermen in Kenya
Despite oral daily HIV pre-exposure prophylaxis (PrEP) effectiveness, uptake remains a challenge. Awareness of one's HIV status and engagement in prevention is essential to interrupting transmission among populations at high risk of HIV. We explored gaps in HIV risk perception, screening, and PrEP uptake among high HIV-risk fishermen living and working along Lake Victoria, Kenya. Data are from the Owete study (NCT04772469), which evaluated the im…
User-informed tailoring of electronic and in-person peer navigation strategies to improve retention in HIV care for adolescents and young adults
Poor adherence and retention in HIV care remain a major challenge among adolescents and young adults (AYA) living with HIV in sub-Saharan Africa (SSA). Strategies are urgently required to support AYA to remain in care for better health outcomes. We explored AYA preferences regarding the format and delivery of electronic and in-person peer navigation to improve HIV care outcomes. This formative qualitative study was conducted among AYA enrolled in…
Training Social Network-Central Fishermen in Western Kenya to Distribute HIV Self-Test Kits and Health Facility Referral Vouchers
Low HIV testing among men, particularly highly mobile fishermen, is a persistent challenge. The Owete study (NCT#04772469) used social network-central men (Promoters) to promote testing and linkage to HIV services among social networks of fishermen in western Kenya. The Promoters and fishermen networks were randomised to intervention or control arms. We describe Owete's interactive training approach and Promoters' training experiences for impleme…
Effects of Alcohol Use on Patient Retention in HIV Care in East Africa
We sought to investigate the association between hazardous alcohol use and gaps in care for people living with HIV over a long-term follow-up period. Adults who had participated in our previously published Phase I study of hazardous alcohol use at HIV programs in Kenya and Uganda were eligible at their 42 to 48 month follow-up visit. Those who re-enrolled were followed for an additional ~ 12 months. Hazardous alcohol use behavior was measured usi…
Social support and the effects of the Covid-19 pandemic among a cohort of people living with HIV (PLWH) in Western Kenya
As coronavirus disease (COVID-19) was declared a pandemic in 2020, countries around the world implemented various prevention strategies, such as banning of public and social gatherings, restriction in movement, etc. These efforts may have had a deleterious effect on already vulnerable populations, including people living with HIV (PLWH). PLWH were concerned about contracting COVID-19, the impact of COVID-19 on their social networks that provide s…
Attitudes towards and experiences with economic incentives for engagement in HIV care and treatment
Growing literature has shown heterogenous effects of conditional cash incentives (CCIs) on HIV care retention. The field lacks insights into reasons why incentives impact various patients in different ways–differences that may be due to variations in psychological and social mechanisms of effect. A deeper understanding of patients’ perceptions and experiences of CCIs for retention may help to clarify these mechanisms. We conducted a qualitative s…
First cases of Sars-CoV-2 infection and secondary transmission in Kisumu, Kenya
We investigated the first 152 laboratory-confirmed SARS-CoV-2 cases (125 primary and 27 secondary) and their 248 close contacts in Kisumu County, Kenya. Conducted June 10–October 8, 2020, this study included interviews and sample collection at enrolment and 14–21 days later. Median age was 35 years (IQR 28–44); 69.0% reported COVID-19 related symptoms, most commonly cough (60.0%), headache (55.2%), fever (53.3%) and loss of taste or smell (43.8%)…
Impact of a Rapid Results Initiative Approach on Improving Male Partner Involvement in Prevention of Mother to Child Transmission of HIV in Western Kenya
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Impact of a Rapid Results Initiative Approach on Improving Male Partner Involvement in Prevention of Mother to Child Transmission of HIV in Western Kenya
Attitudes towards and experiences with economic incentives for engagement in HIV care and treatment
Growing literature has shown heterogenous effects of conditional cash incentives (CCIs) on HIV care retention. The field lacks insights into reasons why incentives impact various patients in different ways–differences that may be due to variations in psychological and social mechanisms of effect. A deeper understanding of patients’ perceptions and experiences of CCIs for retention may help to clarify these mechanisms. We conducted a qualitative s…
First cases of Sars-CoV-2 infection and secondary transmission in Kisumu, Kenya
We investigated the first 152 laboratory-confirmed SARS-CoV-2 cases (125 primary and 27 secondary) and their 248 close contacts in Kisumu County, Kenya. Conducted June 10–October 8, 2020, this study included interviews and sample collection at enrolment and 14–21 days later. Median age was 35 years (IQR 28–44); 69.0% reported COVID-19 related symptoms, most commonly cough (60.0%), headache (55.2%), fever (53.3%) and loss of taste or smell (43.8%)…
Social support and the effects of the Covid-19 pandemic among a cohort of people living with HIV (PLWH) in Western Kenya
As coronavirus disease (COVID-19) was declared a pandemic in 2020, countries around the world implemented various prevention strategies, such as banning of public and social gatherings, restriction in movement, etc. These efforts may have had a deleterious effect on already vulnerable populations, including people living with HIV (PLWH). PLWH were concerned about contracting COVID-19, the impact of COVID-19 on their social networks that provide s…
User-informed tailoring of electronic and in-person peer navigation strategies to improve retention in HIV care for adolescents and young adults
Poor adherence and retention in HIV care remain a major challenge among adolescents and young adults (AYA) living with HIV in sub-Saharan Africa (SSA). Strategies are urgently required to support AYA to remain in care for better health outcomes. We explored AYA preferences regarding the format and delivery of electronic and in-person peer navigation to improve HIV care outcomes. This formative qualitative study was conducted among AYA enrolled in…
Training Social Network-Central Fishermen in Western Kenya to Distribute HIV Self-Test Kits and Health Facility Referral Vouchers
Low HIV testing among men, particularly highly mobile fishermen, is a persistent challenge. The Owete study (NCT#04772469) used social network-central men (Promoters) to promote testing and linkage to HIV services among social networks of fishermen in western Kenya. The Promoters and fishermen networks were randomised to intervention or control arms. We describe Owete's interactive training approach and Promoters' training experiences for impleme…
Effects of Alcohol Use on Patient Retention in HIV Care in East Africa
We sought to investigate the association between hazardous alcohol use and gaps in care for people living with HIV over a long-term follow-up period. Adults who had participated in our previously published Phase I study of hazardous alcohol use at HIV programs in Kenya and Uganda were eligible at their 42 to 48 month follow-up visit. Those who re-enrolled were followed for an additional ~ 12 months. Hazardous alcohol use behavior was measured usi…
Effectiveness and experiences with differentiated service delivery of HIV care in Kisumu County, Kenya
The adoption of the test and treat policy by the World Health Organization (WHO) in 2015 led to an unprecedented increase in the number of people living with HIV (PLHIV) enrolling into HIV treatment, thereby increasing the burden on HIV service delivery. To compensate, WHO endorsed the Differentiated Service Delivery (DSD) approach to reduce the burden on the health care system and therefore support attainment of the UNAIDS 95-95-95 goals by 2030…
Enhancing engagement in HIV care among adolescents and young adults
Structural, psychological, and clinical barriers to HIV care engagement among adolescents and young adults living with HIV (AYAH) persist globally despite gains in HIV epidemic control. Phone-based peer navigation may provide critical peer support, increase delivery flexibility, and require fewer resources. Prior studies show that phone-based navigation and automated text messaging interventions improve HIV care engagement, adherence, and retenti…
Examining and classifying reasons for missing viral loads among adults living with HIV
Gaps in HIV RNA monitoring persist globally impeding the ability to determine clinical progress and outcomes. This study systematically evaluated provider (e.g., guideline non-adherence), system (e.g., laboratory error) and participant-level (e.g., refusal) drivers of missed viral load (VL) monitoring measurements among people with HIV in Kenya. Adults aged 18–65 years were followed across five health facilities in Kenya as part of a clinical tri…
Misconceptions and limited experience with HIV pre-exposure prophylaxis (PrEP) among fishermen in Western Kenya
Daily oral HIV pre-exposure prophylaxis (PrEP) is highly effective when taken consistently, but its uptake remains low among mobile fishermen in Kenya. This study explored barriers and facilitators to PrEP uptake in three Lake Victoria beach communities. In-depth interviews (IDIs) and focus group discussions (FGDs) were conducted with 65 fishermen, purposively sampled by community, age and study arm. IDIs and FGDs examined PrEP knowledge, percept…
Comparing PrEP adherence via objective and self-reported measures among fishermen working on Lake Victoria, Kenya
Fishermen working along Lake Victoria experience high rates of HIV acquisition that can be mitigated by pre-exposure prophylaxis (PrEP), which requires adequate adherence for effective prevention. We evaluated PrEP adherence among Kenyan fishermen using objective metrics and examine non-adherence. Data are from the Owete study (NCT04772469), a cluster randomized-controlled trial using a social network approach among fishermen to increase HIV test…
Experiences and perceptions of conditional cash incentive provision and cessation among people with HIV for care engagement
CCTs do not appear to exert their effects through motivation, but instead act through creating opportunities for better care engagement. This study helps us better understand the durability of financial incentives for HIV care engagement and support the idea that careful consideration be exercised when implementing incentives for sustainable engagement effects
There is no need to leave the beach to test”
While few fishermen had ever used HIVST, this study found high awareness, positive perceptions, and substantial willingness to use and distribute HIVST to other men. The "promoter" model, with known peers engaged in disseminating HIVST information and test kits, shows promise for engaging men in testing
Gaps in Effective HIV Pre-exposure Prophylaxis Screening and Uptake Among Fishermen in Kenya
Despite oral daily HIV pre-exposure prophylaxis (PrEP) effectiveness, uptake remains a challenge. Awareness of one's HIV status and engagement in prevention is essential to interrupting transmission among populations at high risk of HIV. We explored gaps in HIV risk perception, screening, and PrEP uptake among high HIV-risk fishermen living and working along Lake Victoria, Kenya. Data are from the Owete study (NCT04772469), which evaluated the im…
Systematic dissemination of study findings from local to national stakeholders
Disseminating research findings to potential beneficiaries such as study participants, community members, and stakeholders is a critical component of participatory research. While there is general agreement that dissemination is critical, documented examples of comprehensive dissemination activities are few in the literature. We present a concrete example of a multi-level stakeholder dissemination process from a successful HIV self-testing and li…
Social relationships, mental health, and stigma
The disclosure of one’s HIV-positive status is a personal decision that can play an important role in engagement in HIV treatment and care. Social network approaches situate individuals within broader webs of social connections that influence health and wellbeing and thus hold the potential to elucidate key social factors shaping the process of disclosure. As part of a larger clinical study examining how substance use and mental health shape HIV …
HIVST in the presence of a partner among fishermen in Western Kenya
BACKGROUND: HIV self-testing (HIVST) enables individuals to test privately and can serve as an important tool to mitigate stigma and fear of HIV testing and unintended disclosure, especially among men, who have lower voluntary testing rates than women. AIM: Within an intervention study involving distribution of HIVST kits by fishermen to their peers [NCT04772469], we explore the experiences and the motivations of men who chose to self-test for HI…
Motivations for testing and linkage to HIV services following HIV self-testing among fishermen in Kenya
HIV self-testing (HIVST) is a promising strategy to expand testing access for hard-to-reach populations such as Kenyan fishermen. We examined motivations and barriers to HIVST use and linkage to HIV prevention and treatment services (including PrEP or ART), within a social network-based intervention (NCT04772469). We conducted interviews (N = 64) and focus group discussions (N = 4) with fishermen in Siaya County, including 30 “promoters” who dist…
“ I feel like a guest on the other side ”
Adolescents and young adults living with HIV (AYAH) face significant challenges when transitioning from adolescent to adult HIV services. Up to 50% of AYAH do not remain engaged in care after transition, which may result in virological failure. We sought to understand challenges to clinic transitions and youth-identified solutions to optimize health outcomes. We conducted three focus group discussions (FGDs) (n = 33) and a 4-day participatory, hu…
Hazardous alcohol use is associated with sexual behaviors that increase risk for HIV acquisition among fishermen in a high HIV prevalence area of Kenya
Links between hazardous alcohol use and HIV acquisition are well documented, with less known about this relationship among fishermen, a priority group for HIV prevention. We examined associations between hazardous alcohol use and sexual risk behaviors among fishermen in Kenya using 2022 data from 733 fishermen in three Lake Victoria communities. Measures included the AUDIT-C and sexual relationship histories. Logistic regression models assessed a…
HIV/AIDS Research and Interventions (18 obras) · Medicine (14 obras) · Adolescent Sexual and Reproductive Health (13 obras) · Qualitative research (11 obras) · Nursing (10 obras) · Family medicine (8 obras) · Public health (8 obras) · Environmental health (7 obras) · Focus group (7 obras) · Human immunodeficiency virus (HIV) (6 obras)