Mirna Edith Morales-Marín
Datos Biográficos
| ID | 7742760 |
|---|---|
| NOMBRE | Mirna Edith Morales-Marín |
| NOMBRES | Mirna Edith |
| APELLIDO | Morales-Marín |
| FIRMA | MORALES-MARÍN M E |
| AFILIACIONES | National Institute of Genomic Medicine |
| ORCID | 0000-0001-5460-6284 |
| VERIFICADO | Sí |
| TOTAL DE OBRAS | 5 |
| TOTAL DE CITAS | 0 |
| TOTAL COMO AUTOR | 5 |
| TOTAL COMO EDITOR | 0 |
| PRIMER AÑO DE PUBLICACIÓN | 2018 |
| AÑO MÁS RECIENTE DE PUBLICACIÓN | 2025 |
| ÍNDICE H | 0 |
MTHFR C677T is not associated with autism spectrum disorder in a Mexican cohort
Using genetic approaches to study autism spectrum disorder (ASD) is essential to understanding the etiology of the condition. The C677T variant has emerged as a risk factor, and here we present the first association study of this variant in a Mexican population with ASD. Our objective was to assess the variant MTHFR C677T (rs1801133) in a group of Mexican patients with ASD through a case-control association analysis. We found no significant assoc…
Proteome analysis of the prefrontal cortex and the application of machine learning models for the identification of potential biomarkers related to suicide
Our exploratory pathway analysis highlighted oxidative stress responses and neurodevelopmental pathways as key processes perturbed in the DLPFC of suicides. Regarding ML models, KNeighborsClassifier was the best predicting conditions. Here we show that these proteins of the DLPFC may help to identify brain processes associated with suicide and they could be validated as potential biomarkers of this outcome
Epigenome-Wide Analysis Reveals DNA Methylation Alteration in ZFP57 and Its Target RASGFR2 in a Mexican Population Cohort with Autism
Autism Spectrum Disorders (ASD) comprise a group of heterogeneous and complex neurodevelopmental disorders. Genetic and environmental factors contribute to ASD etiology. DNA methylation is particularly relevant for ASD due to its mediating role in the complex interaction between genotype and environment and has been implicated in ASD pathophysiology. The lack of diversity in DNA methylation studies in ASD individuals is remarkable. Since genetic …
Metabolic syndrome in indigenous communities in Mexico
We documented that individuals with Amerindian ancestry have a high prevalence of metabolic syndrome. Health policies are needed to control the development of metabolic disorders in a population with high genetic risk
Demographic and Clinical Characteristics of Completed Suicides in Mexico City 2014–2015
Objective: To analyze sex differences in demographic and clinical characteristics of individuals who died by suicide in Mexico City. Method: Statistical analysis of residents of Mexico City whose cause of death was suicide, during two years period from January 2014 to December 2015, with a coroner's report. Suicide mortality rates were calculated by age, sex, and location within the city. The Chi-squared test was used to assess statistical differ…
Sin obras prominentes en esta página.
Demographic and Clinical Characteristics of Completed Suicides in Mexico City 2014–2015
Objective: To analyze sex differences in demographic and clinical characteristics of individuals who died by suicide in Mexico City. Method: Statistical analysis of residents of Mexico City whose cause of death was suicide, during two years period from January 2014 to December 2015, with a coroner's report. Suicide mortality rates were calculated by age, sex, and location within the city. The Chi-squared test was used to assess statistical differ…
Metabolic syndrome in indigenous communities in Mexico
We documented that individuals with Amerindian ancestry have a high prevalence of metabolic syndrome. Health policies are needed to control the development of metabolic disorders in a population with high genetic risk
Epigenome-Wide Analysis Reveals DNA Methylation Alteration in ZFP57 and Its Target RASGFR2 in a Mexican Population Cohort with Autism
Autism Spectrum Disorders (ASD) comprise a group of heterogeneous and complex neurodevelopmental disorders. Genetic and environmental factors contribute to ASD etiology. DNA methylation is particularly relevant for ASD due to its mediating role in the complex interaction between genotype and environment and has been implicated in ASD pathophysiology. The lack of diversity in DNA methylation studies in ASD individuals is remarkable. Since genetic …
MTHFR C677T is not associated with autism spectrum disorder in a Mexican cohort
Using genetic approaches to study autism spectrum disorder (ASD) is essential to understanding the etiology of the condition. The C677T variant has emerged as a risk factor, and here we present the first association study of this variant in a Mexican population with ASD. Our objective was to assess the variant MTHFR C677T (rs1801133) in a group of Mexican patients with ASD through a case-control association analysis. We found no significant assoc…
Proteome analysis of the prefrontal cortex and the application of machine learning models for the identification of potential biomarkers related to suicide
Our exploratory pathway analysis highlighted oxidative stress responses and neurodevelopmental pathways as key processes perturbed in the DLPFC of suicides. Regarding ML models, KNeighborsClassifier was the best predicting conditions. Here we show that these proteins of the DLPFC may help to identify brain processes associated with suicide and they could be validated as potential biomarkers of this outcome
Medicine (4 obras) · Autism (2 obras) · Autism spectrum disorder (2 obras) · Autism Spectrum Disorder Research (2 obras) · Biology (2 obras) · Demography (2 obras) · Demography (2 obras) · Environmental health (2 obras) · Genetics and Neurodevelopmental Disorders (2 obras) · Internal Medicine (2 obras)