Tisungane Mvalo
Datos Biográficos
| ID | 7747579 |
|---|---|
| NOMBRE | Tisungane Mvalo |
| NOMBRES | Tisungane |
| APELLIDO | Mvalo |
| FIRMA | MVALO T |
| AFILIACIONES | University of North Carolina at Chapel Hill |
| ORCID | 0000-0002-6775-7919 |
| VERIFICADO | Sí |
| TOTAL DE OBRAS | 12 |
| TOTAL DE CITAS | 0 |
| TOTAL COMO AUTOR | 12 |
| TOTAL COMO EDITOR | 0 |
| PRIMER AÑO DE PUBLICACIÓN | 2020 |
| AÑO MÁS RECIENTE DE PUBLICACIÓN | 2025 |
| ÍNDICE H | 0 |
Performance of an artificial intelligence algorithm for interpreting lung sounds from children hospitalised with pneumonia in Malawi
Background: Pneumonia is a leading cause of death in under five year olds globally. World Health Organization (WHO) pneumonia diagnostic guidelines rely on non-specific clinical findings. Lung auscultation could improve pneumonia diagnosis, but conventional stethoscopes have implementation challenges. To address this, we developed an artificial intelligence (AI)-enabled digital auscultation system. We evaluated the system's AI lung sound analysis…
Evaluating the impact of HIV pre-exposure prophylaxis on pregnancy, infant, and maternal health outcomes in Malawi
NCT06158126. The study was prospectively registered (5 December 2023) in ClinicalTrials.gov
Facility-based care for moderately low birthweight infants in India, Malawi, and Tanzania
Globally, increasing rates of facility-based childbirth enable early intervention for small vulnerable newborns. We describe health system-level inputs, current feeding, and discharge practices for moderately low birthweight (MLBW) infants (1500- 10% less than their birthweight; 18.8% of infants were discharged with weights below facility-specific policy [1800g in India, 1500g in Malawi, and 2000g in Tanzania]. Based on descriptive analysis, we f…
World Health Organization Danger Signs to predict bacterial sepsis in young infants
Bacterial sepsis is generally a major concern in ill infants. To help triaging decisions by front-line health workers in these situations, the World Health Organization (WHO) has developed danger signs (DS). The objective of this study was to evaluate the extent to which nine DS predict bacterial sepsis in young infants presenting with suspected sepsis in a low-income country setting. The study pragmatically evaluated nine DS in infants younger t…
Safe infant feeding in healthcare facilities
Infants need to receive care in environments that limit their exposure to pathogens. Inadequate water, sanitation, and hygiene (WASH) environments and suboptimal infection prevention and control practices in healthcare settings contribute to the burden of healthcare-associated infections, which are particularly high in low-income settings. Specific research is needed to understand infant feeding preparation in healthcare settings, a task involvin…
Changes in moderately low birthweight infant feeding, care, and health outcomes before compared to during the Covid-19 pandemic in Malawi
Background: The coronavirus disease 2019 (COVID-19) and the measures taken to minimise its spread have significantly impacted mother- and infant-related healthcare. We describe the changes in newborn feeding, lactation support, and growth outcomes before compared to during the COVID-19 pandemic among moderately low birthweight infants (LBW) (1.5 to <2.5kg) in Malawi. Methods: The data presented here are part of the Low Birthweight Infant Feeding …
Effectiveness of a national mass distribution campaign of long-lasting insecticide-treated nets and indoor residual spraying on clinical malaria in Malawi, 2018–2020
INTRODUCTION: Malawi's malaria burden is primarily assessed via cross-sectional national household surveys. However, malaria is spatially and temporally heterogenous and no analyses have been performed at a subdistrict level throughout the course of a year. The WHO recommends mass distribution of long-lasting insecticide-treated bed nets (LLINs) every 3 years, but a national longitudinal evaluation has never been conducted in Malawi to determine …
Malawian children with chest-indrawing pneumonia with and without comorbidities or danger signs
BACKGROUND: Children with comorbidities or danger signs are often excluded from trials evaluating pneumonia treatment. METHODS: We sought to investigate whether the percentage of children with chest-indrawing pneumonia cured at Day 14 was lower among those with HIV infection or exposure, malaria, moderate or severe acute malnutrition, or anemia enrolled in a prospective observational cohort study than among children without these comorbidities en…
Lessons learned from the development and implementation of an electronic paediatric emergency and acute care database in Lilongwe, Malawi
As the field of global child health increasingly focuses on inpatient and emergency care, there is broad recognition of the need for comprehensive, accurate data to guide decision-making at both patient and system levels. Limited financial and human resources present barriers to reliable and detailed clinical documentation at hospitals in low-and-middle-income countries (LMICs). Kamuzu Central Hospital (KCH) is a tertiary referral hospital in Mal…
Protecting children in low-income and middle-income countries from Covid-19
A saving grace of the COVID-19 pandemic in high-income and upper middle-income countries has been the relative sparing of children. As the disease spreads across low-income and middle-income countries (LMICs), long-standing system vulnerabilities may tragically manifest, and we worry that children will be increasingly impacted, both directly and indirectly. Drawing on our shared child pneumonia experience globally, we highlight these potential im…
Empowering newborn screening programs in African countries through establishment of an international collaborative effort
Environmental modifiers of RTS,S/AS01 malaria vaccine efficacy in Lilongwe, Malawi
Efficacy of GSK Biologicals' Candidate Malaria Vaccine (257049) Against Malaria Disease Caused by P. falciparum Infection in Infants and Children in Africa. NCT00866619 prospectively registered 20 March 2009
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Lessons learned from the development and implementation of an electronic paediatric emergency and acute care database in Lilongwe, Malawi
As the field of global child health increasingly focuses on inpatient and emergency care, there is broad recognition of the need for comprehensive, accurate data to guide decision-making at both patient and system levels. Limited financial and human resources present barriers to reliable and detailed clinical documentation at hospitals in low-and-middle-income countries (LMICs). Kamuzu Central Hospital (KCH) is a tertiary referral hospital in Mal…
Protecting children in low-income and middle-income countries from Covid-19
A saving grace of the COVID-19 pandemic in high-income and upper middle-income countries has been the relative sparing of children. As the disease spreads across low-income and middle-income countries (LMICs), long-standing system vulnerabilities may tragically manifest, and we worry that children will be increasingly impacted, both directly and indirectly. Drawing on our shared child pneumonia experience globally, we highlight these potential im…
Empowering newborn screening programs in African countries through establishment of an international collaborative effort
Environmental modifiers of RTS,S/AS01 malaria vaccine efficacy in Lilongwe, Malawi
Efficacy of GSK Biologicals' Candidate Malaria Vaccine (257049) Against Malaria Disease Caused by P. falciparum Infection in Infants and Children in Africa. NCT00866619 prospectively registered 20 March 2009
Effectiveness of a national mass distribution campaign of long-lasting insecticide-treated nets and indoor residual spraying on clinical malaria in Malawi, 2018–2020
INTRODUCTION: Malawi's malaria burden is primarily assessed via cross-sectional national household surveys. However, malaria is spatially and temporally heterogenous and no analyses have been performed at a subdistrict level throughout the course of a year. The WHO recommends mass distribution of long-lasting insecticide-treated bed nets (LLINs) every 3 years, but a national longitudinal evaluation has never been conducted in Malawi to determine …
Malawian children with chest-indrawing pneumonia with and without comorbidities or danger signs
BACKGROUND: Children with comorbidities or danger signs are often excluded from trials evaluating pneumonia treatment. METHODS: We sought to investigate whether the percentage of children with chest-indrawing pneumonia cured at Day 14 was lower among those with HIV infection or exposure, malaria, moderate or severe acute malnutrition, or anemia enrolled in a prospective observational cohort study than among children without these comorbidities en…
Facility-based care for moderately low birthweight infants in India, Malawi, and Tanzania
Globally, increasing rates of facility-based childbirth enable early intervention for small vulnerable newborns. We describe health system-level inputs, current feeding, and discharge practices for moderately low birthweight (MLBW) infants (1500- 10% less than their birthweight; 18.8% of infants were discharged with weights below facility-specific policy [1800g in India, 1500g in Malawi, and 2000g in Tanzania]. Based on descriptive analysis, we f…
World Health Organization Danger Signs to predict bacterial sepsis in young infants
Bacterial sepsis is generally a major concern in ill infants. To help triaging decisions by front-line health workers in these situations, the World Health Organization (WHO) has developed danger signs (DS). The objective of this study was to evaluate the extent to which nine DS predict bacterial sepsis in young infants presenting with suspected sepsis in a low-income country setting. The study pragmatically evaluated nine DS in infants younger t…
Safe infant feeding in healthcare facilities
Infants need to receive care in environments that limit their exposure to pathogens. Inadequate water, sanitation, and hygiene (WASH) environments and suboptimal infection prevention and control practices in healthcare settings contribute to the burden of healthcare-associated infections, which are particularly high in low-income settings. Specific research is needed to understand infant feeding preparation in healthcare settings, a task involvin…
Changes in moderately low birthweight infant feeding, care, and health outcomes before compared to during the Covid-19 pandemic in Malawi
Background: The coronavirus disease 2019 (COVID-19) and the measures taken to minimise its spread have significantly impacted mother- and infant-related healthcare. We describe the changes in newborn feeding, lactation support, and growth outcomes before compared to during the COVID-19 pandemic among moderately low birthweight infants (LBW) (1.5 to <2.5kg) in Malawi. Methods: The data presented here are part of the Low Birthweight Infant Feeding …
Evaluating the impact of HIV pre-exposure prophylaxis on pregnancy, infant, and maternal health outcomes in Malawi
NCT06158126. The study was prospectively registered (5 December 2023) in ClinicalTrials.gov
Performance of an artificial intelligence algorithm for interpreting lung sounds from children hospitalised with pneumonia in Malawi
Background: Pneumonia is a leading cause of death in under five year olds globally. World Health Organization (WHO) pneumonia diagnostic guidelines rely on non-specific clinical findings. Lung auscultation could improve pneumonia diagnosis, but conventional stethoscopes have implementation challenges. To address this, we developed an artificial intelligence (AI)-enabled digital auscultation system. We evaluated the system's AI lung sound analysis…
Medicine (11 obras) · Environmental health (7 obras) · Pediatrics (6 obras) · Internal Medicine (4 obras) · Pregnancy (4 obras) · Biology (3 obras) · Breastfeeding Practices and Influences (3 obras) · Family medicine (3 obras) · Nursing (3 obras) · Observational study (3 obras)