Charles Olaro
Datos Biográficos
| ID | 7763973 |
|---|---|
| NOMBRE | Charles Olaro |
| NOMBRES | Charles |
| APELLIDO | Olaro |
| FIRMA | OLARO C |
| AFILIACIONES | Ministry of Health |
| ORCID | 0000-0001-8731-7227 |
| VERIFICADO | Sí |
| TOTAL DE OBRAS | 8 |
| TOTAL DE CITAS | 0 |
| TOTAL COMO AUTOR | 8 |
| TOTAL COMO EDITOR | 0 |
| PRIMER AÑO DE PUBLICACIÓN | 2020 |
| AÑO MÁS RECIENTE DE PUBLICACIÓN | 2026 |
| ÍNDICE H | 0 |
Uganda’s cholera elimination journey in a cholera endemic region of Africa
Uganda has been endemic for cholera since 1971. To reduce the threat of cholera, Uganda reviewed its approach to cholera, emphasizing surveillance, continued using single dose doxycycline for cholera patients and their households, and conducted 16 oral cholera vaccine campaigns in high-risk districts between 2018 and 2021.To understand recent changes in cholera patternsand the impact of the OCV campaigns, we classified districts as endemic, elimi…
Wastewater-based surveillance as a proactive public health tool
Wastewater-based surveillance offers a cost-effective, population-level complement to clinical testing for early detection of infectious disease outbreaks; however, its adoption in low- and middle-income countries remains limited. We conducted a study in Kampala, Uganda, to quantify SARS-CoV-2 RNA in wastewater and evaluate its association with reported clinical cases, thereby strengthening community-level surveillance strategies. From March 2023…
The epidemiology and outcomes of adults with acute hypoxaemic respiratory failure in a low-income country in the context of the Covid-19 pandemic
BACKGROUND: Few data regarding the incidence and outcomes of acute hypoxaemic respiratory failure (AHRF) in low- and middle-income countries exist. METHODS: We undertook a prospective, observational multicentre study at 11 Ugandan hospitals (July 2020-April 2021) to determine the prevalence, aetiology and 28-day all-cause mortality of AHRF (acute shortness of breath plus peripheral oxygen saturation 30 breaths per minute (aRR 2.39 (95% CI 1.34 to…
Prediction models for post-discharge mortality among under-five children with suspected sepsis in Uganda
In many low-income countries, over five percent of hospitalized children die following hospital discharge. The lack of available tools to identify those at risk of post-discharge mortality has limited the ability to make progress towards improving outcomes. We aimed to develop algorithms designed to predict post-discharge mortality among children admitted with suspected sepsis. Four prospective cohort studies of children in two age groups (0–6 an…
The epidemiology of antibiotic-resistant clinical pathogens in Uganda
Background: Antibiotic resistance (ABR) is a global challenge, and its control depends on robust evidence primarily derived from surveillance systems. Methods: We utilised a national surveillance data set to demonstrate how such evidence can be systematically generated. In doing so, we characterised the ABR profiles of priority clinical pathogens, identified associated factors, and drew inferences on antibiotic usage in Uganda. Results: Of the 12…
Uptake of reproductive, maternal and child health services during the first year of the Covid-19 pandemic in Uganda
Use of reproductive health (RH), maternal, newborn and child health (MNCH) services in Uganda is suboptimal. Reasons for this are complex; however, service-delivery factors such as availability, quality, staffing, and supplies, contribute substantially to low uptake. The COVID-19 pandemic threatened to exacerbate existing challenges to delivery and use of high-quality RH and MNCH services. We conducted a mixed methods study, combining secondary a…
Hypoxaemia prevalence and management among children and adults presenting to primary care facilities in Uganda
Hypoxaemia (low blood oxygen) is common among hospitalised patients, increasing the odds of death five-fold and requiring prompt detection and treatment. However, we know little about hypoxaemia prevalence in primary care and the role for pulse oximetry and oxygen therapy. This study assessed the prevalence and management of hypoxaemia at primary care facilities in Uganda. We conducted a cross sectional prevalence study and prospective cohort stu…
Uganda’s experience in Ebola virus disease outbreak preparedness, 2018–2019
BACKGROUND: Since the declaration of the 10th Ebola Virus Disease (EVD) outbreak in DRC on 1st Aug 2018, several neighboring countries have been developing and implementing preparedness efforts to prevent EVD cross-border transmission to enable timely detection, investigation, and response in the event of a confirmed EVD outbreak in the country. We describe Uganda's experience in EVD preparedness. RESULTS: On 4 August 2018, the Uganda Ministry of…
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Uganda’s experience in Ebola virus disease outbreak preparedness, 2018–2019
BACKGROUND: Since the declaration of the 10th Ebola Virus Disease (EVD) outbreak in DRC on 1st Aug 2018, several neighboring countries have been developing and implementing preparedness efforts to prevent EVD cross-border transmission to enable timely detection, investigation, and response in the event of a confirmed EVD outbreak in the country. We describe Uganda's experience in EVD preparedness. RESULTS: On 4 August 2018, the Uganda Ministry of…
Hypoxaemia prevalence and management among children and adults presenting to primary care facilities in Uganda
Hypoxaemia (low blood oxygen) is common among hospitalised patients, increasing the odds of death five-fold and requiring prompt detection and treatment. However, we know little about hypoxaemia prevalence in primary care and the role for pulse oximetry and oxygen therapy. This study assessed the prevalence and management of hypoxaemia at primary care facilities in Uganda. We conducted a cross sectional prevalence study and prospective cohort stu…
Uptake of reproductive, maternal and child health services during the first year of the Covid-19 pandemic in Uganda
Use of reproductive health (RH), maternal, newborn and child health (MNCH) services in Uganda is suboptimal. Reasons for this are complex; however, service-delivery factors such as availability, quality, staffing, and supplies, contribute substantially to low uptake. The COVID-19 pandemic threatened to exacerbate existing challenges to delivery and use of high-quality RH and MNCH services. We conducted a mixed methods study, combining secondary a…
Prediction models for post-discharge mortality among under-five children with suspected sepsis in Uganda
In many low-income countries, over five percent of hospitalized children die following hospital discharge. The lack of available tools to identify those at risk of post-discharge mortality has limited the ability to make progress towards improving outcomes. We aimed to develop algorithms designed to predict post-discharge mortality among children admitted with suspected sepsis. Four prospective cohort studies of children in two age groups (0–6 an…
The epidemiology of antibiotic-resistant clinical pathogens in Uganda
Background: Antibiotic resistance (ABR) is a global challenge, and its control depends on robust evidence primarily derived from surveillance systems. Methods: We utilised a national surveillance data set to demonstrate how such evidence can be systematically generated. In doing so, we characterised the ABR profiles of priority clinical pathogens, identified associated factors, and drew inferences on antibiotic usage in Uganda. Results: Of the 12…
The epidemiology and outcomes of adults with acute hypoxaemic respiratory failure in a low-income country in the context of the Covid-19 pandemic
BACKGROUND: Few data regarding the incidence and outcomes of acute hypoxaemic respiratory failure (AHRF) in low- and middle-income countries exist. METHODS: We undertook a prospective, observational multicentre study at 11 Ugandan hospitals (July 2020-April 2021) to determine the prevalence, aetiology and 28-day all-cause mortality of AHRF (acute shortness of breath plus peripheral oxygen saturation 30 breaths per minute (aRR 2.39 (95% CI 1.34 to…
Uganda’s cholera elimination journey in a cholera endemic region of Africa
Uganda has been endemic for cholera since 1971. To reduce the threat of cholera, Uganda reviewed its approach to cholera, emphasizing surveillance, continued using single dose doxycycline for cholera patients and their households, and conducted 16 oral cholera vaccine campaigns in high-risk districts between 2018 and 2021.To understand recent changes in cholera patternsand the impact of the OCV campaigns, we classified districts as endemic, elimi…
Wastewater-based surveillance as a proactive public health tool
Wastewater-based surveillance offers a cost-effective, population-level complement to clinical testing for early detection of infectious disease outbreaks; however, its adoption in low- and middle-income countries remains limited. We conducted a study in Kampala, Uganda, to quantify SARS-CoV-2 RNA in wastewater and evaluate its association with reported clinical cases, thereby strengthening community-level surveillance strategies. From March 2023…
Medicine (4 obras) · Public health (4 obras) · Internal Medicine (3 obras) · Cohort (2 obras) · Cohort study (2 obras) · Disease (2 obras) · Emergency and Acute Care Studies (2 obras) · Environmental health (2 obras) · Epidemiology (2 obras) · Outbreak (2 obras)