J Anthony G Scott

Datos Biográficos

ID7794059
NOMBREJ Anthony G Scott
NOMBRESJ Anthony G
APELLIDOScott
FIRMASCOTT J A G
AFILIACIONESKenya Medical Research Institute
ORCID0000-0001-7533-5006
VERIFICADOSí
TOTAL DE OBRAS12
TOTAL DE CITAS0
TOTAL COMO AUTOR12
TOTAL COMO EDITOR0
PRIMER AÑO DE PUBLICACIÓN2006
AÑO MÁS RECIENTE DE PUBLICACIÓN2026
ÍNDICE H0

  • Trends and patterns of varicella zoster virus infection in Kilifi

    Open AccessAntipa Sigilai, Antipa Kirwa Sigilai et al.ARTICLEPLOS Global Public Health2026

    There is limited epidemiologic data on varicella zoster virus (VZV) infections from low- and middle-income countries including Kenya. We aimed to describe the seroepidemiology of VZV in Kilifi, Kenya, where varicella vaccine is not included in the national infant immunization program, in order to generate evidence to inform vaccine policy. We conducted a retrospective serosurvey utilizing archived plasma and serum samples from cross-sectional pop…

  • Active vaccine safety surveillance

    Open AccessDon B Odhiambo, Donald Akech et al.ARTICLEPLOS Global Public Health2025

    Although active vaccine safety surveillance (VSS) can complement passive VSS while overcoming the inherent limitations of spontaneous safety monitoring, it remains rare in sub-Saharan Africa. We conducted post-authorization active VSS of COVID-19 vaccines in Kilifi, Kenya using a cohort event monitoring study design. Participants were followed weekly over 13 weeks for adverse events. A subset was followed daily for one week for solicited systemic…

  • Use of minimally invasive tissue sampling to determine the contribution of diarrheal diseases to under-five mortality and associated co-morbidities and co-infections in children with fatal diarrheal d…

    Open AccessPortia Mutevedzi, Portia Chipo Mutevedzi et al.ARTICLEPLOS Global Public Health2025

    Achieving the Sustainable Development Goal of reducing child mortality to Shigella /EIEC (14.0%), ST-ETEC (12.4%), rotavirus (26.4%), and adenovirus (non-40/41: 19.0%; 40/41: 5.0%). These pathogens were frequently identified as co-infections. Diarrheal disease accounted for a substantial share of child deaths across CHAMPS sites. Reducing mortality will require preventing diarrhea and addressing key contributors such as malnutrition and HIV

  • The impact of 10-valent pneumococcal conjugate vaccine on the incidence of admissions to hospital with hypoxaemic and non-hypoxaemic pneumonia in Kenyan children

    Open AccessIlsa L Haeusler, Eunice Wangeci Kagucia et al.ARTICLEPLOS Global Public Health2025

    Observational evidence suggests that pneumococcal conjugate vaccines (PCVs) are more effective at reducing the incidence of hypoxaemic pneumonia compared to non-hypoxaemic pneumonia. We examined the impact of 10-valent PCV (PCV10, Synflorix) on hypoxaemic pneumonia hospital admissions using data from an existing PCV impact study of clinical and radiographic pneumonia. PCV10 was introduced, with catch-up among children under 5 years, in the Kilifi…

  • Contribution of malnutrition to infant and child deaths in Sub-Saharan Africa and South Asia

    Open AccessZachary J Madewell, Adama Mamby Keita et al.ARTICLEBMJ Global Health2024

    Introduction Malnutrition contributes to 45% of all childhood deaths globally, but these modelled estimates lack direct measurements in countries with high malnutrition and under-5 mortality rates. We investigated malnutrition’s role in infant and child deaths in the Child Health and Mortality Prevention Surveillance (CHAMPS) network. Methods We analysed CHAMPS data from seven sites (Bangladesh, Ethiopia, Kenya, Mali, Mozambique, Sierra Leone and…

  • Identifying delays in healthcare seeking and provision

    Open AccessElisa Garcia Gomez, Kitiezo Aggrey Igunza et al.ARTICLEPLOS Global Public Health2024

    Delays in illness recognition, healthcare seeking, and in the provision of appropriate clinical care are common in resource-limited settings. Our objective was to determine the frequency of delays in the “Three Delays-in-Healthcare”, and factors associated with delays, among deceased infants and children in seven countries with high childhood mortality. We conducted a retrospective, descriptive study using data from verbal autopsies and medical r…

  • Causes of death identified in neonates enrolled through Child Health and Mortality Prevention Surveillance (CHAMPS), December 2016 –December 2021

    Open AccessSana Mahtab, Shabir A Madhi et al.ARTICLEPLOS Global Public Health2023

    Each year, 2.4 million children die within their first month of life. Child Health and Mortality Prevention Surveillance (CHAMPS) established in 7 countries aims to generate accurate data on why such deaths occur and inform prevention strategies. Neonatal deaths that occurred between December 2016 and December 2021 were investigated with MITS within 24–72 hours of death. Testing included blood, cerebrospinal fluid and lung cultures, multi-pathoge…

  • Epidemiological impact and cost-effectiveness analysis of Covid-19 vaccination in Kenya

    Open AccessStacey Orangi, John Ojal et al.ARTICLEBMJ Global Health2022

    BACKGROUND: A few studies have assessed the epidemiological impact and the cost-effectiveness of COVID-19 vaccines in settings where most of the population had been exposed to SARS-CoV-2 infection. METHODS: We conducted a cost-effectiveness analysis of COVID-19 vaccine in Kenya from a societal perspective over a 1.5-year time frame. An age-structured transmission model assumed at least 80% of the population to have prior natural immunity when an …

  • Sars-CoV-2 seroprevalence in three Kenyan health and demographic surveillance sites, December 2020-May 2021

    Open AccessAnthony Etyang, Ifedayo Adetifa et al.ARTICLEPLOS Global Public Health2022

    Background Most of the studies that have informed the public health response to the COVID-19 pandemic in Kenya have relied on samples that are not representative of the general population. We conducted population-based serosurveys at three Health and Demographic Surveillance Systems (HDSSs) to determine the cumulative incidence of infection with SARS-CoV-2. Methods We selected random age-stratified population-based samples at HDSSs in Kisumu, Nai…

  • UK prevalence of underlying conditions which increase the risk of severe Covid-19 disease

    Open AccessJemma Walker, Jemma L Walker et al.ARTICLEBMC Public Health2021

    The population at risk of severe COVID-19 (defined as either aged ≥70 years, or younger with an underlying health condition) comprises 18.5 million individuals in the UK, including a considerable proportion of school-aged and working-aged individuals. Our national estimates broadly support the use of Global Burden of Disease modelled estimates in other countries. We provide age- and region- stratified prevalence for each condition to support effe…

  • Geographic access to care is not a determinant of child mortality in a rural Kenyan setting with high health facility density

    Open AccessJennifer C Moïsi, Hellen Gatakaa et al.ARTICLEBMC Public Health2010

    Significant spatial variations in mortality were observed across the area, but were not correlated with distance to health facilities. We conclude that given the present density of health facilities in Kenya, geographic access to curative services does not influence population-level mortality

  • Immunization coverage and risk factors for failure to immunize within the Expanded Programme on Immunization in Kenya after introduction of new Haemophilus influenzae type b and hepatitis b virus anti…

    Open AccessMoses Ndiritu, Karen D Cowgill et al.ARTICLEBMC Public Health2006

    Vaccine coverage was high before and after introduction of pentavalent vaccine, but most doses were given late. Coverage is limited by seasonal factors and family size