John W Eaton
Datos Biográficos
| ID | 87099 |
|---|---|
| NOMBRE | John W Eaton |
| NOMBRES | John W |
| APELLIDO | Eaton |
| FIRMA | EATON J W |
| AFILIACIONES | Imperial College London |
| ORCID | 0000-0001-7728-728X |
| VERIFICADO | Sí |
| TOTAL DE OBRAS | 31 |
| TOTAL DE CITAS | 13 |
| TOTAL COMO AUTOR | 31 |
| TOTAL COMO EDITOR | 0 |
| PRIMER AÑO DE PUBLICACIÓN | 1937 |
| AÑO MÁS RECIENTE DE PUBLICACIÓN | 2026 |
| ÍNDICE H | 2 |
Towards ending tuberculosis in South Africa
Distribution and transmission of M. tuberculosis in a high-HIV prevalence city in Malawi
Delays in identifying and treating individuals with infectious tuberculosis (TB) contribute to poor health outcomes and allow ongoing community transmission of M. tuberculosis ( Mtb ). Current recommendations for screening for tuberculosis specify community characteristics (e.g., areas with high local tuberculosis prevalence) that can be used to target screening within the general population. However, areas of higher tuberculosis burden are not n…
HIV incidence and prevalence projections for Zimbabwe
Introduction : Understanding how HIV epidemics are likely to behave in the future is key to informing HIV response strategies in low-income countries. Up-to-date HIV epidemiological estimates are important for policy decision- making, but surveillance data can be out of date. This study compared forecasts from HIV epidemiological models. Methods : Five independent modelling groups (EMOD-HIV, Goals, HIV Synthesis, Optima and PopART-IBM) calibrated…
Pregnancy reporting and biases in under-five mortality in three African HDSSs
In the absence of complete civil registration and vital statistics, Health and Demographic Surveillance Systems (HDSSs) are important sources of population-based data throughout sub-Saharan Africa. However, HDSS data on the vital status of newborns are often unreliable due to omission of those who were born and died between two rounds of data collection and are therefore never enumerated. This study investigates whether pregnancy registration imp…
HIV risk behaviour, viraemia, and transmission across HIV cascade stages including low-level viremia
As antiretroviral treatment (ART) coverage for people living with HIV (PLHIV) increases, HIV programmes require up-to-date information about evolving HIV risk behaviour and transmission risk, including those with low-level viremia (LLV; >50 to ≤1000 copies/mL), to guide prevention priorities. We aimed to assess differences in sexual risk behaviours, distribution of viral load (VL) and proportion of transmission across PLHIV subgroups. We analysed…
Association Between Early Sexual Debut and New HIV Infections Among Adolescents and Young Adults in 11 African Countries
We investigated the association between early sexual debut and HIV infection among adolescents and young adults. Analyzing data from nationally representative Population-Based HIV Impact Assessment (PHIA) surveys in 11 African countries, the research employed a multivariate logistic regression model to assess the relationship between the early sexual debut and new HIV infections in the age group of 10-24 years. The results revealed a significant …
From the comments section
This study explores the analysis of public reactions to presidential debates using a largely untapped social media data source—YouTube comments. My findings reveal a striking consistency in topics across YouTube channels, pointing to a shared perspective among viewers that goes beyond ideological differences. These results question the assumption that online behavior mirrors traditional media preferences, suggesting that viewers may not apply ide…
Characteristics of male perpetrators of intimate partner violence and implications for women’s HIV status
Intimate partner violence (IPV) may increase women’s HIV acquisition risk. Still, knowledge on pathways through which IPV exacerbates HIV burden is emerging. We examined the individual and partnership-level characteristics of male perpetrators of physical and/or sexual IPV and considered their implications for women’s HIV status. We pooled individual-level data from nationally representative, cross-sectional surveys in 27 countries in Africa (200…
Spatio-temporal estimates of HIV risk group proportions for adolescent girls and young women across 13 priority countries in sub-Saharan Africa
The Global AIDS Strategy 2021-2026 identifies adolescent girls and young women (AGYW) as a priority population for HIV prevention, and recommends differentiating intervention portfolios geographically based on local HIV incidence and individual risk behaviours. We estimated prevalence of HIV risk behaviours and associated HIV incidence at health district level among AGYW living in 13 countries in sub-Saharan Africa. We analysed 46 geospatially-re…
Trends and country-level variation in age at first sex in sub-Saharan Africa among birth cohorts entering adulthood between 1985 and 2020
AFS increased slightly in most SSA countries, but changes were modest relative to large and persistent variation between countries and sexes, indicating relatively entrenched socio-cultural practices around sexual debut. Sexual health, family planning, and HIV/STI prevention services should adapt to local practices rather than focusing interventions to change AFS. These estimates for rates of sexual debut provide data to guide programmatic priori…
Incidence and predictors of attrition among patients receiving ART in eastern Zimbabwe before, and after the introduction of universal ‘treat-all’ policies
As HIV treatment is expanded, attention is focused on minimizing attrition from care. We evaluated the impact of treat-all policies on the incidence and determinants of attrition amongst clients receiving ART in eastern Zimbabwe. Data were retrospectively collected from the medical records of adult patients (aged≥18 years) enrolled into care from July 2015 to June 2016—pre-treat-all era, and July 2016 to June 2017—treat-all era, selected from 12 …
Age patterns of under-5 mortality in sub-Saharan Africa during 1990-2018
BACKGROUND: Estimates of under-5 mortality (U5M) for sub-Saharan African populations often rely heavily on full birth histories (FBHs) collected in surveys and model age patterns of mortality calibrated against vital statistics from other populations. Health and Demographic Surveillance Systems (HDSSs) are alternate sources of population-based data in much of sub-Saharan Africa, which are less formally utilized in estimation. OBJECTIVE: In this s…
Estimating the effects of non-pharmaceutical interventions on Covid-19 in Europe
Spillover HIV prevention effects of a cash transfer trial in East Zimbabwe
ClinicalTrials.gov , NCT00966849 . Registered August 27, 2009
Population-level adult mortality following the expansion of antiretroviral therapy in Rakai, Uganda
There are limited data on the impact of antiretroviral therapy (ART) on population-level adult mortality in sub-Saharan Africa. We analysed data for 2000-14 from the Rakai Community Cohort Study (RCCS) in Uganda, where free ART was scaled up after 2004. Using non-parametric and parametric (Weibull) survival analysis, we estimated trends in average person-years lived between exact ages 15 and 50, per capita life-years lost to HIV, and the mortalit…
Mapping HIV prevalence in sub-Saharan Africa between 2000 and 2017
HIV/AIDS is a leading cause of disease burden in sub-Saharan Africa. Existing evidence has demonstrated that there is substantial local variation in the prevalence of HIV; however, subnational variation has not been investigated at a high spatial resolution across the continent. Here we explore within-country variation at a 5 × 5-km resolution in sub-Saharan Africa by estimating the prevalence of HIV among adults (aged 15–49 years) and the corres…
Non-disclosure of HIV testing history in population-based surveys
Background: HIV/AIDS programmes and organisations around the world use routinely updated estimates of the UNAIDS 90-90-90 targets to track progress and prioritise further programme implementation. Any bias in these estimates has the potential to mislead organisations on where gaps exist in HIV testing and treatment programmes. Objective: To measure the extent of undisclosed HIV testing history and its impact on estimating the proportion of people…
Prevalence and Associations of Psychological Distress, HIV Infection and HIV Care Service Utilization in East Zimbabwe
The correlation between mental health and sexual risk behaviours for HIV infection remains largely unknown in low and middle income settings. The present study determined the prevalence of psychological distress (PD) in a sub-Saharan African population with a generalized HIV epidemic, and investigated associations with HIV acquisition risk and uptake of HIV services using data from a cross-sectional survey of 13,252 adults. PD was measured using …
Education, substance use, and HIV risk among orphaned adolescents in Eastern Zimbabwe
There is a growing interest in education as a means to reduce HIV infection in vulnerable children in sub-Saharan Africa; however, the mechanisms by which education reduces HIV infection remain uncertain. Substance use has been associated with high-risk sexual behaviour and could lie on the causal pathway between education and HIV risk. Therefore, we used multivariable regression to measure associations between: (i) orphanhood and substance use (…
The relationship between parental education and children’s schooling in a time of economic turmoil
Using data collected from 1998 to 2011 in a general population cohort study in eastern Zimbabwe, we describe education trends and the relationship between parental education and children's schooling during the Zimbabwean economic collapse of the 2000s. During this period, the previously-rising trend in education stalled, with girls suffering disproportionately; however, female enrolment increased as the economy began to recover. Throughout the pe…
Effects of cash transfers on Children’s health and social protection in Sub-Saharan Africa
Orphaned children are at higher risk for poor social protection outcomes even when cared for in family-based settings. UCT and CCT each produced direct effects on children's social protection which are not moderated by other child- and household-level risk factors, but orphans are less likely to attend school or obtain birth registration. The effects of UCT and CCT are not moderated by asset-holding, but greater household assets predict greater s…
The impact of HIV on children's education in eastern Zimbabwe
Little is known about how HIV impacts directly and indirectly on receiving, or particularly succeeding in, education in sub-Saharan Africa. To address this gap, we used multivariable logistic regression to determine the correlation between education outcomes in youth (aged 15-24) (being in the correct grade-for-age, primary school completion and having at least five "O" level passes) and being HIV-positive; having an HIV-positive parent; being a …
Effects of unconditional and conditional cash transfers on child health and development in Zimbabwe
Asset ownership among households caring for orphans and vulnerable children in rural Zimbabwe
The high prevalence of human immunodeficiency virus/acquired immune deficiency syndrome in sub-Saharan Africa has resulted in a dramatic increase in orphans and vulnerable children (OVC) over the past decade. These children typically rely on extended family networks for support, but the magnitude of the crisis has resulted in traditional familial networks becoming overwhelmed and more economically and socially vulnerable. Previous research consis…
Involving Communities in the Targeting of Cash Transfer Programs for Vulnerable Children
We used baseline data, collected in July-September 2009, from a randomized controlled trial of a cash transfer program for vulnerable children in eastern Zimbabwe to investigate the effectiveness, coverage, and efficiency of census- and community-based targeting methods for reaching vulnerable children. Focus group discussions and in-depth interviews with beneficiaries and other stakeholders were used to explore community perspectives on targetin…
Household-based cash transfer targeting strategies in Zimbabwe
Involving Communities in the Targeting of Cash Transfer Programs for Vulnerable Children
We used baseline data, collected in July-September 2009, from a randomized controlled trial of a cash transfer program for vulnerable children in eastern Zimbabwe to investigate the effectiveness, coverage, and efficiency of census- and community-based targeting methods for reaching vulnerable children. Focus group discussions and in-depth interviews with beneficiaries and other stakeholders were used to explore community perspectives on targetin…
Age patterns of under-5 mortality in sub-Saharan Africa during 1990-2018
BACKGROUND: Estimates of under-5 mortality (U5M) for sub-Saharan African populations often rely heavily on full birth histories (FBHs) collected in surveys and model age patterns of mortality calibrated against vital statistics from other populations. Health and Demographic Surveillance Systems (HDSSs) are alternate sources of population-based data in much of sub-Saharan Africa, which are less formally utilized in estimation. OBJECTIVE: In this s…
The relationship between parental education and children’s schooling in a time of economic turmoil
Using data collected from 1998 to 2011 in a general population cohort study in eastern Zimbabwe, we describe education trends and the relationship between parental education and children's schooling during the Zimbabwean economic collapse of the 2000s. During this period, the previously-rising trend in education stalled, with girls suffering disproportionately; however, female enrolment increased as the economy began to recover. Throughout the pe…
Sensitivity to P‐T‐C among primates
The taste threshold of 228 subjects from 17 species of non‐human primates was determined with graded solutions of P‐T‐C. Among species for which the sample size was sufficiently large, only the chimpanzee definitely showed a bimodal distribution. Experiments with tyrosine and cabbage indicate that the concentration of the former, in saliva, influences the individual's threshold and that the amount of cabbage, or other goitrogens, in the diet prob…
Education in Present-Day Germany
The German Universities and National Socialism
Sensitivity to P‐T‐C among primates
The taste threshold of 228 subjects from 17 species of non‐human primates was determined with graded solutions of P‐T‐C. Among species for which the sample size was sufficiently large, only the chimpanzee definitely showed a bimodal distribution. Experiments with tyrosine and cabbage indicate that the concentration of the former, in saliva, influences the individual's threshold and that the amount of cabbage, or other goitrogens, in the diet prob…
Concurrent Sexual Partnerships and Primary HIV Infection
The Internal Protection Alternative Under European Union Law
The European Union is currently in the process of revising the central directives that make up European Union refugee law, a project that will touch on almost every aspect of seeking asylum in Europe. This article will focus on the implementation of one doctrine, the internal protection or internal flight alternative, under the recently recast Qualification Directive. The article will first examine the application of the internal protection alter…
Household-based cash transfer targeting strategies in Zimbabwe
Effects of unconditional and conditional cash transfers on child health and development in Zimbabwe
Asset ownership among households caring for orphans and vulnerable children in rural Zimbabwe
The high prevalence of human immunodeficiency virus/acquired immune deficiency syndrome in sub-Saharan Africa has resulted in a dramatic increase in orphans and vulnerable children (OVC) over the past decade. These children typically rely on extended family networks for support, but the magnitude of the crisis has resulted in traditional familial networks becoming overwhelmed and more economically and socially vulnerable. Previous research consis…
Involving Communities in the Targeting of Cash Transfer Programs for Vulnerable Children
We used baseline data, collected in July-September 2009, from a randomized controlled trial of a cash transfer program for vulnerable children in eastern Zimbabwe to investigate the effectiveness, coverage, and efficiency of census- and community-based targeting methods for reaching vulnerable children. Focus group discussions and in-depth interviews with beneficiaries and other stakeholders were used to explore community perspectives on targetin…
The impact of HIV on children's education in eastern Zimbabwe
Little is known about how HIV impacts directly and indirectly on receiving, or particularly succeeding in, education in sub-Saharan Africa. To address this gap, we used multivariable logistic regression to determine the correlation between education outcomes in youth (aged 15-24) (being in the correct grade-for-age, primary school completion and having at least five "O" level passes) and being HIV-positive; having an HIV-positive parent; being a …
Effects of cash transfers on Children’s health and social protection in Sub-Saharan Africa
Orphaned children are at higher risk for poor social protection outcomes even when cared for in family-based settings. UCT and CCT each produced direct effects on children's social protection which are not moderated by other child- and household-level risk factors, but orphans are less likely to attend school or obtain birth registration. The effects of UCT and CCT are not moderated by asset-holding, but greater household assets predict greater s…
The relationship between parental education and children’s schooling in a time of economic turmoil
Using data collected from 1998 to 2011 in a general population cohort study in eastern Zimbabwe, we describe education trends and the relationship between parental education and children's schooling during the Zimbabwean economic collapse of the 2000s. During this period, the previously-rising trend in education stalled, with girls suffering disproportionately; however, female enrolment increased as the economy began to recover. Throughout the pe…
Prevalence and Associations of Psychological Distress, HIV Infection and HIV Care Service Utilization in East Zimbabwe
The correlation between mental health and sexual risk behaviours for HIV infection remains largely unknown in low and middle income settings. The present study determined the prevalence of psychological distress (PD) in a sub-Saharan African population with a generalized HIV epidemic, and investigated associations with HIV acquisition risk and uptake of HIV services using data from a cross-sectional survey of 13,252 adults. PD was measured using …
Education, substance use, and HIV risk among orphaned adolescents in Eastern Zimbabwe
There is a growing interest in education as a means to reduce HIV infection in vulnerable children in sub-Saharan Africa; however, the mechanisms by which education reduces HIV infection remain uncertain. Substance use has been associated with high-risk sexual behaviour and could lie on the causal pathway between education and HIV risk. Therefore, we used multivariable regression to measure associations between: (i) orphanhood and substance use (…
Non-disclosure of HIV testing history in population-based surveys
Background: HIV/AIDS programmes and organisations around the world use routinely updated estimates of the UNAIDS 90-90-90 targets to track progress and prioritise further programme implementation. Any bias in these estimates has the potential to mislead organisations on where gaps exist in HIV testing and treatment programmes. Objective: To measure the extent of undisclosed HIV testing history and its impact on estimating the proportion of people…
Mapping HIV prevalence in sub-Saharan Africa between 2000 and 2017
HIV/AIDS is a leading cause of disease burden in sub-Saharan Africa. Existing evidence has demonstrated that there is substantial local variation in the prevalence of HIV; however, subnational variation has not been investigated at a high spatial resolution across the continent. Here we explore within-country variation at a 5 × 5-km resolution in sub-Saharan Africa by estimating the prevalence of HIV among adults (aged 15–49 years) and the corres…
Estimating the effects of non-pharmaceutical interventions on Covid-19 in Europe
Spillover HIV prevention effects of a cash transfer trial in East Zimbabwe
ClinicalTrials.gov , NCT00966849 . Registered August 27, 2009
Population-level adult mortality following the expansion of antiretroviral therapy in Rakai, Uganda
There are limited data on the impact of antiretroviral therapy (ART) on population-level adult mortality in sub-Saharan Africa. We analysed data for 2000-14 from the Rakai Community Cohort Study (RCCS) in Uganda, where free ART was scaled up after 2004. Using non-parametric and parametric (Weibull) survival analysis, we estimated trends in average person-years lived between exact ages 15 and 50, per capita life-years lost to HIV, and the mortalit…
Incidence and predictors of attrition among patients receiving ART in eastern Zimbabwe before, and after the introduction of universal ‘treat-all’ policies
As HIV treatment is expanded, attention is focused on minimizing attrition from care. We evaluated the impact of treat-all policies on the incidence and determinants of attrition amongst clients receiving ART in eastern Zimbabwe. Data were retrospectively collected from the medical records of adult patients (aged≥18 years) enrolled into care from July 2015 to June 2016—pre-treat-all era, and July 2016 to June 2017—treat-all era, selected from 12 …
Age patterns of under-5 mortality in sub-Saharan Africa during 1990-2018
BACKGROUND: Estimates of under-5 mortality (U5M) for sub-Saharan African populations often rely heavily on full birth histories (FBHs) collected in surveys and model age patterns of mortality calibrated against vital statistics from other populations. Health and Demographic Surveillance Systems (HDSSs) are alternate sources of population-based data in much of sub-Saharan Africa, which are less formally utilized in estimation. OBJECTIVE: In this s…
Trends and country-level variation in age at first sex in sub-Saharan Africa among birth cohorts entering adulthood between 1985 and 2020
AFS increased slightly in most SSA countries, but changes were modest relative to large and persistent variation between countries and sexes, indicating relatively entrenched socio-cultural practices around sexual debut. Sexual health, family planning, and HIV/STI prevention services should adapt to local practices rather than focusing interventions to change AFS. These estimates for rates of sexual debut provide data to guide programmatic priori…
Characteristics of male perpetrators of intimate partner violence and implications for women’s HIV status
Intimate partner violence (IPV) may increase women’s HIV acquisition risk. Still, knowledge on pathways through which IPV exacerbates HIV burden is emerging. We examined the individual and partnership-level characteristics of male perpetrators of physical and/or sexual IPV and considered their implications for women’s HIV status. We pooled individual-level data from nationally representative, cross-sectional surveys in 27 countries in Africa (200…
Spatio-temporal estimates of HIV risk group proportions for adolescent girls and young women across 13 priority countries in sub-Saharan Africa
The Global AIDS Strategy 2021-2026 identifies adolescent girls and young women (AGYW) as a priority population for HIV prevention, and recommends differentiating intervention portfolios geographically based on local HIV incidence and individual risk behaviours. We estimated prevalence of HIV risk behaviours and associated HIV incidence at health district level among AGYW living in 13 countries in sub-Saharan Africa. We analysed 46 geospatially-re…
HIV risk behaviour, viraemia, and transmission across HIV cascade stages including low-level viremia
As antiretroviral treatment (ART) coverage for people living with HIV (PLHIV) increases, HIV programmes require up-to-date information about evolving HIV risk behaviour and transmission risk, including those with low-level viremia (LLV; >50 to ≤1000 copies/mL), to guide prevention priorities. We aimed to assess differences in sexual risk behaviours, distribution of viral load (VL) and proportion of transmission across PLHIV subgroups. We analysed…
Medicine (21 obras) · Demography (20 obras) · Environmental health (18 obras) · Population (16 obras) · Adolescent Sexual and Reproductive Health (12 obras) · HIV/AIDS Research and Interventions (12 obras) · Poverty, Education, and Child Welfare (9 obras) · Demography (8 obras) · Global Maternal and Child Health (8 obras) · Psychological intervention (8 obras)