Leonid Kalichman
Datos Biográficos
| ID | 96062 |
|---|---|
| NOMBRE | Leonid Kalichman |
| NOMBRES | Leonid |
| APELLIDO | Kalichman |
| FIRMA | KALICHMAN L |
| AFILIACIONES | Ben-Gurion University of the Negev |
| ORCID | 0000-0003-2987-4396 |
| VERIFICADO | Sí |
| TOTAL DE OBRAS | 38 |
| TOTAL DE CITAS | 14 |
| TOTAL COMO AUTOR | 38 |
| TOTAL COMO EDITOR | 0 |
| PRIMER AÑO DE PUBLICACIÓN | 2002 |
| AÑO MÁS RECIENTE DE PUBLICACIÓN | 2026 |
| ÍNDICE H | 2 |
Effect of Brief Guided Imagery on Short-Term Outcomes in Patients Undergoing First Elective Total Knee Arthroplasty
Background : Knee osteoarthritis, which is prevalent among older adults, often necessitates total knee arthroplasty (TKA) to alleviate pain and improve function. Postoperative pain and functional limitations remain significant challenges. Brief guided imagery (GI), a non-pharmacological intervention, shows promise in pain management but is underexplored in TKA patients. Aim : The aim of this study is to evaluate the effect of brief GI on postoper…
A Pilot Randomized Controlled Trial of Extracorporeal Vaginal Peflex Weights for Enhancing Pelvic Floor Function and Relieving Stress Urinary Incontinence
Peflex weights effectively reduce SUI symptoms and improve muscle power and endurance, with high user satisfaction. However, there was no significant difference in the main outcome measure (ICIQ-UI-SF) between the Peflex and control groups. Further research is needed to identify which patients benefit most from this treatment
Pelvic Floor Disorders Due to Anal Sexual Activity in Men and Women
Recent evidence shows that consensual anal penetrative intercourse has become more prevalent, not only limited to gay, bisexual, and other men who have sex with men but also for women who are in a sexual relationship with men. The aim of this review was to study the influence of consensual anal intercourse on pelvic floor function and the role of pelvic floor physical therapy treatment in preventing or treating consensual anal intercourse-induced…
Variability of Somatotypes According to Heath-Carter in Adult Chuvash People
Introduction. In the range of topical problems of modern human morphology, the doctrine of bodily constitution occupies an important place, but there is a shortage of data on population variability of somatotypes in the literature. The purpose of this cross-sectional study was to study age and sex variations in body composition components using the Heath-Carter method in the Chuvash rural population examined in several villages in the Mariinsky-P…
Prevalence and characteristics of radiographic hand osteoarthritis in rural Turkmens
Introduction. The knowledge about the prevalence of hand osteoarthritis (OA) in different populations, the pattern of joint involvement, and the association with age, sex, and weight might be helpful in the understanding of the etiology and in developing the prevention strategy of hand OA. It can be important from a public health perspective. The study aimed to evaluate the prevalence and pattern of radiographic hand OA in the Turkmen community-b…
Hand osteoarthritis
Objective: The aim of the study was to explore whether the development of radiographic hand osteoarthritis (OA) is affected more by ethnicity or environment, comparing five Russian community-based samples living in different geographical locations and two ethnic groups, Russian and Buryats, who reside in the same geographic area. Material and methods. Cross-sectional observational study. The study population comprised ethnic Russians (821 males a…
Starvation May Change the Type of Paternal but Not Maternal Inheritance of the Telomere Length Throughout Generations
Our aim was to evaluate the effect of starvation on the paternal and maternal inheritance of the leucocyte telomere length (LTL) in three birth cohorts: before, during, and after the Chuvashian famine of 1922–1923. This retrospective cohort study comprised native Chuvash men (n= 678) and women (n=647) born between 1909–1980. Data were gathered during three expeditions: 1994, 1999, 2002, enabling us to treat age and birth year as independent varia…
Hospital-Based Rehabilitation of Patients Who Had Undergone an Open Reduction and Internal Fixation of the Ribs Due to a Flail Chest
Flail chest, a severe chest injury, is caused by multiple rib fractures. The open reduction and internal fixation (ORIF) of rib fractures is an effective treatment; however, the patients' subsequent condition remains unsatisfactory in terms of the activities of daily living (ADL) and pain. No research study has, as yet, reported on hospital-based rehabilitation of patients who had undergone an ORIF. Our aim was to evaluate the efficacy of hospita…
A Combination of Long-Duration Electrical Stimulation with External Shoulder Support during Routine Daily Activities in Patients with Post-Hemiplegic Shoulder Subluxation
The study objective was to determine the effect of long-duration neuromuscular electric stimulation (NMES) on shoulder subluxation and upper-extremity function during the acute post-stroke stage. Twenty-eight subjects (mean age ± standard deviation -70.0 ± 14.0 years) were randomly assigned to an experimental or to a control group receiving NMES to the supraspinatus and posterior deltoid muscles or sham treatment for 6 weeks. All the subjects con…
Heritability of 2D
A Chuvashian population-based sample included 802 males and 738 females (mean age 46.98±17.10 and 48.65±16.62 years, correspondingly). Age, basic demographics, anthropometric data, reproductive indices, and x-rays of both hands were collected. Results and discussion. Familial correlations of FLR traits showed no significant correlation for spouses, however, parent-offspring (0.15-0.28, p
Taste sensitivity to phenylthiocarbamide found in South Sinai Bedouin tribes
The aim of this work was to study taste sensitivity to phenylthiocarbamide (PTC) amongst Bedouin tribes and compare the Bedouins with Arab and Jewish populations. Data obtained by the classic method of serial dilutions in 317 healthy male Bedouins, aged 16–70 belonging to different tribes, were examined. We discovered significant differences in chemosensitivity to PTC in the Bedouin communities. A high frequency of the t allele was documented in…
Finger length ratio in longevity populations
OBJECTIVES: The purpose of this study was to compare the prevalence of finger length ratio between three longevity populations (Abkhazians, Azerbaijanis, and Georgians) and one nonlongevity population (Russians), as well as between a longevity and nonlongevity sample within one ethnic group (Abkhazians). METHODS: In a cross-sectional observational study, we compared the prevalence of finger length ratio in longevity vs nonlongevity samples. RESUL…
Finger Length Ratio (2D
This study aimed to evaluate the association between the index to ring (2D:4D) finger length ratio and aging-related traits (hand osteoarthritis (OA), the osseographic score (OSS), and reproductive period), as well as to assess the heritability of finger length. A Chuvashian population-based sample included 802 males (mean age 46.98±17.10 years) and 738 females (mean age 48.65±16.62 years). Age, sex, basic demographics, anthropometric data, repro…
Heritability estimation of 2D
Objectives The purpose of this study was to evaluate the familial correlations and heritability of 2D:4D ratio traits using a large population‐based sample of ethnically homogeneous pedigrees from Chuvasha and Bashkortostan Autonomies of the Russian Federation. Methods We calculated the familial correlations and performed a heritability analysis of 2D:4D ratio traits in a sample of 1541 subjects (803 men and 738 women, mean age 47.78 ± 16.89 year…
Finger length (2D
D
0.33) ratio. Finger length ratio is associated with an OSS, a skeletal biomarker of biological aging. Individuals with Type 3 finger length pattern showed significantly higher OSS that ones with Type 1 and Type 2.
Digit ratio and laterality indices
The aim of the present study was to evaluate the association between digit ratio indices (representing the prenatal androgen and estrogen exposure) and different laterality indices, handedness (HDD), the dominant eye (DE), hand clasping (HCL) and arm folding (ARMF) in a large (N=1,586) Chuvashian population-based sample.HDD showed a significant association with the right phalangeal length ratio, the right and the left metacarpal ratio and the rig…
D
D
We found that a low 2D:4D ratio (radiologically evaluated), a masculine 2D:4D ratio type (visually evaluated), and a putative bioassay for prenatal androgen exposure, were associated with a later menarche and a shorter reproductive period. No association was found with menopausal age
Hand osteoarthritis and aging
Background : Because osteoarthritis (OA) is associated with morbidity and mortality, we hypothesized that radiographic hand OA would generally be associated with chronic systemic morbidity and it will be less prevalent in longevity populations than in non-longevity populations. Aims : 1) to evaluate the association between chronic systemic morbidity and radiographic hand OA; 2) to compare the prevalence and the mode of the development of radiogra…
Climate is associated with prevalence and severity of radiographic hand osteoarthritis
Climatic factors in the development of radiographic hand osteoarthritis
Hand osteoarthritis in the Abkhazian population
Age-related changes and secular trends in hand bone size
Laterality indices in the Chuvashian population
The aim of the present study was to describe the frequencies of right or left dominance in handedness (HDD), dominant eye (DE), hand clasping (HCL) and arm folding (ARMF) and their combination in the Chuvashian population. We also evaluated the familial correlation and heritability of aforementioned traits in the studied population. The investigated cohort comprised 235 nuclear Chuvashian (Russia) families and included 595 men aged 18-89 years (m…
Secular Trends of Reproductive Indices in Chuvashian Women
In the present cross-sectional study of the Chuvashian rural population, we examined the secular trends of age at menarche, the age at menopause, the reproductive period, and the age of the first marriage of Chuvashian women. The cohort included 745 women aged 18–90 years; age at menarche (N = 653) ranging from 10 to 24 years (mean 15.42 ± 2.11). Data regarding menopausal age was obtained from 316 women born between 1920 and 1950 (mean 48.5 ± 4.6…
Mode of Inheritance of Hand Osteoarthritis in Ethnically Homogeneous Pedigrees
The aim of the present study was to investigate the extent and mode of inheritance of hand osteoarthritis (OA) using a large sample of ethnically homogeneous pedigrees. Two types of segregation analysis (SA) models were examined. Type I models used the data adjusted for potential significant covariates, particularly age and sex, prior to genetic analysis. Type 11 models incorporated effects of the potential covariates into major gene penetrance f…
Association Between Morbidity and Skeletal Biomarkers of Biological Aging
The Osseographic Scoring System (OSS) is a synthetic measure of skeletal aging that combines osteoporotic and osteoarthritic changes of the hand. The OSS is used to evaluate biological age in a population. The aim of the present study was to evaluate the association between certain chronic morbidities and the skeletal biomarker of biological aging. We performed a population-based study on a large sample of individuals who were receiving no medica…
Association between physique characteristics and hand skeletal aging status
The aim of the present study was to evaluate the association between skeletal aging traits (obtained from evaluation of hand radiographs) and physique characteristics, including indices of obesity, skeletal size, muscular development, and the somatotypes of Heath and Carter (1967) and of Deriabin (1985). To achieve our aims, we used multiple regression analysis, and Pearson's and canonical correlation analyses. The studied population comprised 62…
Interrelationship between bone aging traits and basic anthropometric characteristics
Using plain hand radiographs, the age dependence of various bone‐aging traits (bone mineral density [BMD], cortical index [CI], osteoarthritis [OA], and osseographic [OSS] scores) was evaluated to test whether the correlation among these traits is an individual‐ or population‐based phenomenon. In addition, the effect of anthropometric features on variation of bone‐aging traits was estimated. The study included 1,295 individuals from Chuvasha, Rus…
Mode of Inheritance of Hand Osteoarthritis in Ethnically Homogeneous Pedigrees
The aim of the present study was to investigate the extent and mode of inheritance of hand osteoarthritis (OA) using a large sample of ethnically homogeneous pedigrees. Two types of segregation analysis (SA) models were examined. Type I models used the data adjusted for potential significant covariates, particularly age and sex, prior to genetic analysis. Type 11 models incorporated effects of the potential covariates into major gene penetrance f…
Patterns of joint distribution in hand osteoarthritis
The most frequent site of osteoarthritis (OA) is the hands, but the pattern of hand OA development remains controversial. Understanding these patterns may assist in evaluating biological aging, determining etiology, and proposing ways of preventing hand OA. We investigated the pattern distribution of OA in hands and the influences of age, sex, and handedness on its development. The study population was comprised of Chuvashians (660 males age 18–8…
Association between somatotypes and blood pressure in an adult Chuvasha population
Individuals of robust physique (with high endomorphy and mesomorphy) showed high mean values of systolic and diastolic BP, whereas the smallest persons had the lowest BP values. These findings suggest the existence of common physiological paths in the development of body physique and blood pressure regulation and may possibly be indicative of the involvement of pleiotropic genetic and/or epigenetic mechanisms in this regulation
Repeated measurement study of hand osteoarthritis in an apparently healthy Caucasian population
The rate of hand osteoarthritis (OA) progression remains controversial due to a shortage of longitudinal studies. We performed a longitudinal, 8-year follow-up study to evaluate the rate of hand OA progression in men and women. This analysis included the influence of age, sex, anthropometric traits, baseline level of hand OA, smoking, alcohol consumption, and familial effects on the progression rate of hand OA. The collected data included informa…
Association between physique characteristics and hand skeletal aging status
The aim of the present study was to evaluate the association between skeletal aging traits (obtained from evaluation of hand radiographs) and physique characteristics, including indices of obesity, skeletal size, muscular development, and the somatotypes of Heath and Carter (1967) and of Deriabin (1985). To achieve our aims, we used multiple regression analysis, and Pearson's and canonical correlation analyses. The studied population comprised 62…
Sex- and age-related variations of the somatotype in a Chuvasha population
Indices of body composition and chronic morbidity
Our objective was to clarify how different groups of chronic morbidities are associated with indices of body composition, such as body mass index (BMI), waist circumference (WC), waist to hip ratio (WHR), skinfold index (SF), and fat-free mass index (FFMI). Our sample comprised Chuvasha residing in numerous villages in a rural area of the Russian Federation. The investigated cohort included 787 males aged 18-89 years, and 716 females aged 18-90 y…
Variation of skeletal biomarkers of biological aging in a Chuvashian population
Osseographic score (OSS) is a skeletal biomarker of biological aging, based on assessment of the hand's radiographic features. The aims of the present cross-sectional and follow-up study were: 1) to evaluate age-related changes of OSS in a large Chuvashian cohort, and 2) to evaluate sex differences in age-related changes of OSS. This study reports on intersexual differences in the pattern of skeletal aging. The most prominent difference was in th…
Age at menarche in a Chuvashian rural population
Our study demonstrated the certain secular trends of age at menarche in Chuvashian women who matured after World War II. Periods of socio-economic disasters such as war and famine disrupt the secular trend. Our findings also confirm the hypothesis of significant familial influences on menarcheal age
Association Between Morbidity and Skeletal Biomarkers of Biological Aging
The Osseographic Scoring System (OSS) is a synthetic measure of skeletal aging that combines osteoporotic and osteoarthritic changes of the hand. The OSS is used to evaluate biological age in a population. The aim of the present study was to evaluate the association between certain chronic morbidities and the skeletal biomarker of biological aging. We performed a population-based study on a large sample of individuals who were receiving no medica…
Secular Trends of Reproductive Indices in Chuvashian Women
In the present cross-sectional study of the Chuvashian rural population, we examined the secular trends of age at menarche, the age at menopause, the reproductive period, and the age of the first marriage of Chuvashian women. The cohort included 745 women aged 18–90 years; age at menarche (N = 653) ranging from 10 to 24 years (mean 15.42 ± 2.11). Data regarding menopausal age was obtained from 316 women born between 1920 and 1950 (mean 48.5 ± 4.6…
Search for Hand Osteoarthritis Susceptibility Locus on Chromosome 6p12.3-p12.1
The existence of osteoarthritis susceptibility loci on chromosome 6 for individuals suffering from hip and knee osteoarthritis has been suggested. We determined whether radiographic hand osteoarthritis in a demographically homogeneous population of European origin can be linked to loci on chromosome 6p12.3-p12.1. Nine single nucleotide polymorphisms (SNPs) were genotyped in 764 individuals (members of 189 nuclear and more complex two- or three-ge…
Age-related changes and secular trends in hand bone size
Laterality indices in the Chuvashian population
The aim of the present study was to describe the frequencies of right or left dominance in handedness (HDD), dominant eye (DE), hand clasping (HCL) and arm folding (ARMF) and their combination in the Chuvashian population. We also evaluated the familial correlation and heritability of aforementioned traits in the studied population. The investigated cohort comprised 235 nuclear Chuvashian (Russia) families and included 595 men aged 18-89 years (m…
Hand osteoarthritis in the Abkhazian population
Climatic factors in the development of radiographic hand osteoarthritis
Climate is associated with prevalence and severity of radiographic hand osteoarthritis
Hand osteoarthritis and aging
Background : Because osteoarthritis (OA) is associated with morbidity and mortality, we hypothesized that radiographic hand OA would generally be associated with chronic systemic morbidity and it will be less prevalent in longevity populations than in non-longevity populations. Aims : 1) to evaluate the association between chronic systemic morbidity and radiographic hand OA; 2) to compare the prevalence and the mode of the development of radiogra…
D
D
We found that a low 2D:4D ratio (radiologically evaluated), a masculine 2D:4D ratio type (visually evaluated), and a putative bioassay for prenatal androgen exposure, were associated with a later menarche and a shorter reproductive period. No association was found with menopausal age
Digit ratio and laterality indices
The aim of the present study was to evaluate the association between digit ratio indices (representing the prenatal androgen and estrogen exposure) and different laterality indices, handedness (HDD), the dominant eye (DE), hand clasping (HCL) and arm folding (ARMF) in a large (N=1,586) Chuvashian population-based sample.HDD showed a significant association with the right phalangeal length ratio, the right and the left metacarpal ratio and the rig…
D
0.33) ratio. Finger length ratio is associated with an OSS, a skeletal biomarker of biological aging. Individuals with Type 3 finger length pattern showed significantly higher OSS that ones with Type 1 and Type 2.
Finger length (2D
Heritability estimation of 2D
Objectives The purpose of this study was to evaluate the familial correlations and heritability of 2D:4D ratio traits using a large population‐based sample of ethnically homogeneous pedigrees from Chuvasha and Bashkortostan Autonomies of the Russian Federation. Methods We calculated the familial correlations and performed a heritability analysis of 2D:4D ratio traits in a sample of 1541 subjects (803 men and 738 women, mean age 47.78 ± 16.89 year…
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