Uptake of Recommended Vaccines During Pregnancy Among Publicly and Privately Insured People in the United States, December 2020–September 2022
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Objectives. To estimate maternal COVID-19, influenza, and pertussis vaccine uptake during pregnancy by insurance type and identify factors characterizing those vaccinated and unvaccinated. Methods. We conducted a US cohort study of pregnant individuals (for pregnancies ending December 11, 2020–September 30, 2022) using insurance claims data. We calculated vaccination probability using Kaplan-Meier methods and identified factors associated with vaccination through binomial regression with inverse probability weights. Results. Among 695 887 pregnant individuals (median age = 32 years for privately and 27 years for publicly insured), the cumulative probability of COVID-19 vaccination was 43.0% (privately insured) and 11.8% (publicly insured). We observed marked disparities between influenza (33.2% vs 14.2%) and pertussis (70.3% vs 42.8%) vaccination. Only 6.8% (privately insured) and 1.1% (publicly insured) received all 3 vaccines. COVID-19 and influenza vaccination odds were lower among drug and tobacco users. People with high-risk medical conditions, particularly the publicly insured, commonly were vaccinated. Conclusions. Marked vaccine uptake disparities exist between privately and publicly insured pregnant people. Understanding structural barriers, particularly for Medicaid enrollees, is critical to improving maternal vaccine access. ( Am J Public Health. 2025;115(3):354–363. https://doi.org/10.2105/AJPH.2024.307899 )
Coronavirus disease 2019 (COVID-19) · Disease · Environmental health · Family medicine · Health care · Immunization · Logistic regression · Medicaid · Odds · Odds ratio · Pandemic · Pertussis vaccine · Pregnancy · Public health · Vaccination · COVID-19 Impact on Reproduction · Demography · Global Maternal and Child Health · Immunology · Internal Medicine · Medicine · Pregnancy and Medication Impact · Virology
The REporting of studies Conducted using Observational Routinely-collected health Data (Record) Statement
Clinical manifestations, risk factors, and maternal and perinatal outcomes of coronavirus disease 2019 in pregnancy
Adverse maternal, fetal, and newborn outcomes among pregnant women with Sars-CoV-2 infection
Protection of Racial/Ethnic Minority Populations During an Influenza Pandemic
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