Incidence of adverse events related to health care in Spain

Results of the Spanish National Study of Adverse Events

Datos Bibliográficos

ID11178571
AutoresJ M Aranaz-Andrés, Jesús María Aranaz Andrés (0000-0002-3658-0321, Universitat de Miguel Hernández d'Elx), C Aibar-Remón (Universidad de Zaragoza), J Vitaller-Murillo (Universitat de Miguel Hernández d'Elx), P Ruiz-López, Pedro Ruiz López (0000-0002-1903-058X, Research Institute Hospital 12 de Octubre), Ramón Limón-Ramírez (Universitat de Miguel Hernández d'Elx), Enrique Terol-García (Ministry of Health)
Año2008
Volumen62
Número12
Páginas1022-1029
Fecha de publicación2008-12-01
Peer ReviewedSí
Open AccessNo
TipoARTICLE
RevistaJournal of Epidemiology and Community Health (JOURNAL)
Identificadores de la revistaISSN: 0143-005X • E-ISSN: 1470-2738
EditorialBMJ (PUBLISHER • GB)
DOI10.1136/jech.2007.065227
PMID19008366
OpenAlexW2157835363
IdiomaEN
Citas recibidas16
Referencias citadas23

OBJECTIVE: To determine the incidence and incidence density of adverse events (AEs) in Spanish hospitals (including the pre-hospitalisation period). METHOD: Retrospective cohort study. RESULTS: The incidence of patients with AEs relating directly to hospital care was 8.4% (95% CI 7.7% to 9.1%) and rose 9.3% (95% CI 8.6% to 10.1%), including those from the pre-hospitalisation period. The incidence density was 1.2 AEs per 100 patient-days (95% CI 1.1 to 1.3). The incidence of moderate and serious AEs was 5.6 AEs per 1000 patient-days (95% CI 4.9% to 6.3%). In 66.3% of AEs, additional procedures were required and in 69.9% additional treatments were required. In total 42.8% of AEs were considered as avoidable. Of the subjects with some intrinsic risk factors, 13.2% developed AEs compared with 5.2% of the subjects who had no risk factors (p<0.001), and 9.5% of the subjects who had some extrinsic risk factors developed AEs compared with 3.4% of the subjects who had not (p<0.001). Patients older than 65 years of age showed a higher frequency of AEs than those under this age (12.4% vs 5.4%, p<0.001, RR 2.5). The most frequent AEs were those associated with medication (37.4%), hospital infections of any type (25.3%) and those relating to technical problems during a procedure (25.0%). A total of 31.4% of the AEs involved an increase in the length of stay. The AEs associated with medical assistance caused 6.1 additional hospital stays by patient. CONCLUSIONS: The incidence of patients with AE related to medical assistance in Spanish hospitals was relevant and similar to those found in the studies from Canada and New Zealand that had been conducted with comparable methodology. Patient vulnerability has been identified therein as playing a major role in generating healthcare-related AEs. These and other recent results indicate the need for AEs to be considered a public health priority in Europe

Adverse effect · Cohort study · Incidence (geometry) · Retrospective cohort study · Internal Medicine · Medical Malpractice and Liability Issues · Medicine · Patient Safety and Medication Errors · Pharmacovigilance and Adverse Drug Reactions · Pediatrics