Medline-based assessment of animal studies on Chinese herbal medicine

Datos Bibliográficos

ID14726751
AutoresNoelia Tejedor Garcia (Universidad de Alcalá), Laura Garcia Bermejo, Laura García‐Bermejo (0000-0002-8167-2276, Instituto Ramón y Cajal de Investigación Sanitaria), Ana Belen Fernandez Martinez, Ana B Fernández‐Martínez (0000-0002-5653-7769, Universidad de Alcalá), Gemma Olmos Centenera, Gemma Olmos (0000-0003-4835-0846, Universidad de Alcalá), Rajendra Kumari (0000-0001-8961-1681, University of Nottingham), Qihe Xu (0000-0002-8015-2674, King's College London), Xiaodong Cheng (0000-0002-6967-6362, Tongji University), Sue Watson, Sue‐Ann Watson (0000-0002-9818-7429, University of Nottingham), Francisco Javier de Lucio Cazaña, Francisco Javier Lucio-Cazaña (0000-0001-9249-8501, Universidad de Alcalá, autor de correspondencia)
Año2012
Volumen140
Número3
Páginas545-549
Fecha de publicación2012-04-01
Peer ReviewedSí
Open AccessSí
TipoARTICLE
RevistaJournal of Ethnopharmacology (JOURNAL)
Identificadores de la revistaISSN: 0378-8741 • E-ISSN: 1872-7573
EditorialElsevier BV (PUBLISHER)
DOI10.1016/j.jep.2012.02.008
PMID22353429
OpenAlexW2071173879
IdiomaEN
Citas recibidas2
Referencias citadas10

UNLABELLED: ETHNO-PHARMACOLOGICAL RELEVANCE: The scientific proof and clinical validation of Chinese herbal medicine (CHM) require a rigorous approach that includes chemical standardization, biological assays, animal studies and clinical trials. AIM OF THE STUDY: To assess the experimental design of animal studies on the activity of CHM by selection and scrutinizing of a series of papers in some major disease areas. MATERIALS AND METHODS: We have analyzed the English publications reported in MEDLINE (ISI web of knowledge). RESULTS: Our data showed that (i) research of CHM during the last 10 years had been highly intensified and become more accessible worldwide through increased publications in English, although still most authors had Chinese names; (ii) English journals publishing animal research of CHM were comparable to those publishing animal studies of non-Chinese phytotherapy in terms of impact factor; and (iii) published data on authentication and quality control of CHM, as well as research design of animal studies were far from sufficient to meet the criteria needed to support their reproducibility and reliability. CONCLUSIONS AND PERSPECTIVES: The recent decade witnessed an increase in CHM research activities and CHM English publications. Based on common problems identified in publications on CHM animal studies, we have proposed a checklist that could help in preliminary selection of publications lacking the most common problems and thus would be useful for a quick search of reproducible CHM regimens that are likely to be effective in a given context. The second application of this checklist is to help avoid the most common problems when designing experiments

Alternative medicine · Animal testing · Biology · Checklist · Clinical trial · MEDLINE · Pathology · Publishing · Traditional medicine · Andrographolide Research and Applications · Medicine · Plant-based Medicinal Research · Psychology · Traditional Chinese Medicine Analysis