Buyang huanwu decoction combined with BMSCs transplantation promotes recovery after spinal cord injury by rescuing axotomized red nucleus neurons

Datos Bibliográficos

ID14727636
AutoresPing Yang (0000-0002-3646-438X, Hunan Institute of Mental Health), An Chen (0000-0002-6275-759X, Hunan University of Traditional Chinese Medicine), You Qin (0000-0002-6582-1526, Hunan Academy of Traditional Chinese Medicine), Jian Yin (0000-0003-1203-5537, Hunan University of Traditional Chinese Medicine), Xiong Cai (0000-0003-4644-4451, Hunan University of Traditional Chinese Medicine), Yu-jie Fan, Yujie Fan (0000-0001-7892-0171, Hunan Institute of Mental Health), Liang Li (0000-0002-1688-1143, Hunan University of Traditional Chinese Medicine, autor de correspondencia), Hui-yong Huang, Huiyong Huang (0000-0001-7803-3425, Hunan University of Traditional Chinese Medicine, autor de correspondencia)
Año2019
Volumen228
Páginas123-131
Fecha de publicación2019-01-01
Peer ReviewedSí
Open AccessSí
TipoARTICLE
RevistaJournal of Ethnopharmacology (JOURNAL)
Identificadores de la revistaISSN: 0378-8741 • E-ISSN: 1872-7573
EditorialElsevier BV (PUBLISHER)
DOI10.1016/j.jep.2018.09.028
PMID30266421
OpenAlexW2894049849
IdiomaEN
Citas recibidas1
Referencias citadas28

BYHWD combined with BMSCs transplantation had synergistic effect on neuroprotection of red nucleus neurons after SCI; the mechanism may be related to up-regulating cAMP level, activating the cAMP/CREB/RhoA signaling pathway, and promoting expression of NGF

Biology · CREB · Neuroprotection · Nissl body · Nucleus · Pathology · Red nucleus · RHOA · Signal transduction · Spinal cord · Spinal cord injury · Staining · Medicine · Nerve injury and regeneration · Neurogenesis and neuroplasticity mechanisms · Neuroscience · Spinal Cord Injury Research · Biochemistry · Cell Biology · Internal Medicine · Pharmacology · Transplantation