Safety and anti-inflammatory activity of Gentiana lutea L. in human bronchial epithelial cell cultures

Datos Bibliográficos

ID14736813
AutoresJoanne Wildhaber (University of Fribourg), Bedia Begum Karakocak (0000-0001-9676-7465, Adolphe Merkle Institute), Mauro Sousa de Almeida (Adolphe Merkle Institute), Barbara Rothen-Rutishauser (Adolphe Merkle Institute), Alke Petri-Fink, Alke Petri‐Fink (0000-0003-3952-7849, Adolphe Merkle Institute), Johannes Wildhaber (University of Fribourg), Benedikt Huber (0000-0003-2952-3879), Benedikt Maria Huber (University of Fribourg, autor de correspondencia)
Año2026
Volumen361
Páginas121254
Fecha de publicación2026-04-01
Peer ReviewedSí
Open AccessSí
TipoARTICLE
RevistaJournal of Ethnopharmacology (JOURNAL)
Identificadores de la revistaISSN: 0378-8741 • E-ISSN: 1872-7573
EditorialElsevier BV (PUBLISHER)
DOI10.1016/j.jep.2026.121254
PMID41580168
OpenAlexW7125385229
IdiomaEN
Referencias citadas77

An aqueous G. lutea root extract is safe to use and exhibits direct anti-inflammatory effects in bronchial epithelial tissues in vitro. These findings provide the first experimental support of its traditional use in respiratory diseases and warrant further preclinical and clinical evaluation

Aqueous extract · Biological activity · Cell culture · Epithelium · In vitro · Pharmacognosy · Respiratory system · Respiratory tract · Ethnobotanical and Medicinal Plants Studies · Natural product bioactivities and synthesis · Phytochemistry and Biological Activities