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A novel mechanism for regulating lung immune homeostasis

Zukamu granules alleviated acute lung injury in mice by inhibiting NLRP3 inflammasome activation and regulating Th17/Treg cytokine balance

Datos Bibliográficos

ID14745249
AutoresChenqian Yu (Beijing University of Chinese Medicine), Yanan Li (0000-0002-9456-4514, Beijing University of Chinese Medicine), Yixuan Li (0009-0004-6861-0654, Beijing University of Chinese Medicine), Siyu Li (0000-0003-2198-7548, Beijing University of Chinese Medicine), Fengping Zeng (Beijing University of Chinese Medicine), Jing Yu (0000-0002-0142-6391, Xinjiang Medical University), Zhihong Ji, Keao Li (0000-0003-1310-4039), Huaqiang Zhai (0000-0001-9652-9491, Xinjiang Medical University, autor de correspondencia)
Año2024
Volumen324
Páginas117831
Fecha de publicación2024-04-01
Peer ReviewedSí
Open AccessSí
TipoARTICLE
RevistaJournal of Ethnopharmacology (JOURNAL)
Identificadores de la revistaISSN: 0378-8741 • E-ISSN: 1872-7573
EditorialElsevier BV (PUBLISHER)
DOI10.1016/j.jep.2024.117831
PMID38280662
OpenAlexW4391247791
IdiomaEN
Citas recibidas1
Referencias citadas52

ZKMG can reduce the degree of lung tissue injury in ALI by inhibiting NLRP3/Caspase-1/GSDMD signaling pathway and restoring the IL-17A/IL-10 cytokine balance, and its protective mechanism may be related to the regulation of lung immune homeostasis. It will provide a new strategy for studying the regulation of lung immune homeostasis

Biology · Cytokine · Immune system · Inflammasome · Inflammation · Lipopolysaccharide · Lung · Signal transduction · Western blot · Biomarkers in Disease Mechanisms · Inflammasome and immune disorders · Medicinal Plants and Bioactive Compounds · Medicine · Cell Biology · Immunology · Internal Medicine · Pharmacology

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Obras citantes distintas1
Citas por año0,5
Intervalo de citas2024 - 2024 (1)
Velocidad de citaciónrecent
Altamente citadoNo
Tipos de citaNeutras: 1
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