Adverse pregnancy and perinatal outcomes in Latin America and the Caribbean

Systematic review and meta-analysis

Datos Bibliográficos

ID14968909
AutoresEstela Blanco (0000-0002-6232-9210, Facultad de Medicina, Pontifica Universidad Católica, Santiago, Chile.), Marin Marcela (University of Talca), Loreto Núñez (0000-0001-5397-2506, University of Talca), Erika Retamal (University of Talca), Ximena Ossa (Universidad de La Frontera), Katherine E Woolley (0000-0003-3743-9925, University of Birmingham), Tosin Oludotun (University of Birmingham), Suzanne E Bartington (University of Birmingham), Juana Maria Delgado-Saborit (0000-0002-7096-9744, Universitat Jaume I), R M Harrison (0000-0002-2684-5226, University of Birmingham), Pablo Ruiz-Rudolph (0000-0001-7872-2546, University of Chile), Maria Elisa Quinteros (0000-0001-8815-1513, University of Talca)
Año2022
Volumen46
Páginas1
Fecha de publicación2022-05-02
Peer ReviewedSí
Open AccessSí
TipoARTICLE
RevistaRevista Panamericana de Salud Pública (JOURNAL)
Identificadores de la revistaISSN: 1020-4989 • E-ISSN: 1680-5348
EditorialPan American Health Organization (PUBLISHER • US)
DOI10.26633/rpsp.2022.21
IdiomaEN
Citas recibidas2
Referencias citadas54

Objective. To estimate the point prevalence and likely ranges of pregnancy-induced hypertension, pre-eclampsia, gestational diabetes, low birth weight and preterm delivery in Latin America and the Caribbean, and evaluate the heterogeneity of the estimates. Methods. We conducted a systematic review and meta-analysis of observational studies reporting the prevalence of maternal and perinatal adverse outcomes in populations in Latin American and the Caribbean published between 2000 and 2019 in English, Spanish, or Portuguese. We searched PubMed, Embase, and LILACS. We estimated the point prevalence and evaluated overall heterogeneity and, in sub-group analyses, heterogeneity by study design and level of bias. Results. Of 1087 records retrieved, 50 articles were included in the review: two on hypertensive disorders of pregnancy, 14 on pre-eclampsia, six on gestational diabetes, nine on low birth weight and 19 on preterm birth. No meta-analysis for hypertensive disorders of pregnancy could be done because of the small number of studies. Point prevalence estimates and 95% confidence intervals (CIs) for pre-eclampsia, gestational diabetes, low birth weight, and preterm birth were: 6.6% (95% CI: 4.9%, 8.6%), 8.5% (95% CI: 3.9%, 14.7%), 8.5% (95% CI: 7.2%, 9.8%), and 10.0% (95% CI: 8.0%, 12.0%), respectively. We observed substantial heterogeneity overall and by study design. No major differences in estimates were observed by level of bias. Conclusions. The results of this study provide updated estimates of some of the most prevalent adverse pregnancy and perinatal outcomes in Latin America and the Caribbean. They highlight that important heterogeneity exists in prevalence estimates, which may reflect the diversity of populations in the region