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Relationship of sleep duration with incident cardiovascular outcomes

A prospective study of 33,883 adults in a general population

Datos Bibliográficos

ID15358193
AutoresHui Cui (0000-0003-4281-016X, Fudan University, autor de correspondencia), Rong Xu (0000-0001-5651-4738, Fudan University), Yiming Wan (0000-0002-1315-9120, Fudan University), Yong Ling (0000-0002-2628-4203, Fudan University), Yonggen Jiang (Songjiang District Central Hospital), Yi‐Ling Wu (0000-0002-5937-6753, Songjiang District Central Hospital), Yiling Wu (0000-0002-1882-0184), Ying Guan (0000-0002-1021-9917, Songjiang District Central Hospital), Qi Zhao (0000-0002-6885-7583, Fudan University), Genming Zhao (0000-0002-3160-809X, Fudan University), Maryam Zaid (0009-0008-5478-2091, Fudan University)
Año2023
Volumen23
Número1
Fecha de publicación2023-01-18
Peer ReviewedSí
Open AccessSí
TipoARTICLE
RevistaBMC Public Health (JOURNAL)
Identificadores de la revistaISSN: 1471-2458 • E-ISSN: 1471-2458
EditorialBioMed Central (PUBLISHER • GB)
DOI10.1186/s12889-023-15042-x
OpenAlexW4317105240
IdiomaEN
Referencias citadas30

Background Studies on the effect of sleep duration on cardiovascular health have contradictory findings. Underlying health issues may have led to inconsistent results and warrant consideration. We aim to assess the relationship of night sleep duration with incident cardiovascular disease (CVD) in a general population, taking into consideration underlying chronic diseases. Methods Data from Shanghai Suburban Adult Cohort and Biobank with a median follow-up of 5.1 years was used, including 33,883 adults aged 20–74 years old. Incident CVD cases were reported and recorded by the Center for Disease Prevention and Control in Songjiang, Shanghai. We used Cox proportional hazard regression models and restricted cubic spline (RCS) analysis to explore the relationship between different sleep groups and sleep duration with incident CVD outcomes, through stratification by gender and age, as well as different health conditions, with adjustments for potential confounders. Results Long sleep duration (> 9 h) compared to > 7 to ≤ 8 h was associated with overall incident CVD in participants aged ≥ 50 years old: HR(95%CI) = 2.07 (1.15, 3.74) for 50-59y and 1.43 (1.04, 1.93) for 60-74y. RCS analysis showed a J-shaped relationship between sleep and CVD risk in those ≥ 50y, which was confirmed only in those with a chronic health condition. Non-linear relationships between sleep and CVD risk factors, such as BMI, blood glucose and glycated haemoglobin, were observed. Conclusions Long sleep duration is associated with increased risk of CVD in people ≥ 50y. However, CVD risk factors and underlying health conditions such as hypertension, and diabetes, may play a driving role in the relationship

Biostatistics · Cohort · Cohort study · Confidence interval · Confounding · Disease · Environmental health · Hazard ratio · Incidence (geometry · Population · Proportional hazards model · Prospective cohort study · Demography · Medicine · Obesity, Physical Activity, Diet · Sleep and related disorders · Sleep and Work-Related Fatigue · Epidemiology · Internal Medicine · Pediatrics

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  • Modeling the change trajectory of sleep duration and its associated factors

    Open Access•Junyan Fang, Zhuoyi Wen et al.•BMC Public Health•2021

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