Prenatal Exposure to Perfluoroalkyl Substances and Birth Outcomes; An Updated Analysis from the Danish National Birth Cohort
Datos Bibliográficos
| ID | 15480970 |
|---|---|
| Autores | Qi Meng (0009-0009-2377-5187, University of California, Los Angeles), K Inoue (0000-0001-9614-8103, University of California, Los Angeles), Beate Ritz (0000-0001-6976-7339, University of California, Los Angeles), Jørn Olsen (0000-0001-7462-2740, Aarhus University Hospital), Zeyan Liew (0000-0002-9424-7869, University of California, Los Angeles, autor de correspondencia) |
| Año | 2018 |
| Volumen | 15 |
| Número | 9 |
| Páginas | 1832-1832 |
| Fecha de publicación | 2018-08-24 |
| Peer Reviewed | Sí |
| Open Access | Sí |
| Tipo | ARTICLE |
| Revista | International Journal of Environmental Research and Public Health (JOURNAL) |
| Identificadores de la revista | ISSN: 1661-7827 • E-ISSN: 1660-4601 |
| Editorial | Multidisciplinary Digital Publishing Institute (PUBLISHER • CH) |
| DOI | 10.3390/ijerph15091832 |
| PMID | 30149566 |
| OpenAlex | W2796876645 |
| Idioma | EN |
| Citas recibidas | 3 |
| Referencias citadas | 51 |
Perfluoroalkyl substances (PFASs) are widespread industrial pollutants that are extremely persistent in the environment. A previous study in the Danish National Birth Cohort (DNBC) found prenatal perfluorooctanoate (PFOA) exposure was associated with decreased birth weight, but had insufficient statistical power to evaluate adverse birth outcomes. Here, we conducted additional analyses in three samples originating from the DNBC for 3535 mothers and infant pairs to evaluate associations between prenatal PFASs exposures and low birth weight and preterm birth. Maternal plasma concentrations were measured for six types of PFASs in early pregnancy. Several PFASs were associated with a reduction in birth weight and gestational age. We estimated a nearly 2-fold increase in risks of preterm birth for the higher quartiles of PFOA and perflourooctanesulfonate (PFOS) exposure. In spline models, risk of preterm birth was increased for perfluorononanoic acid (PFNA), perfluoroheptane sulfonate (PFHpS) and perfluorodecanoic acid (PFDA) in higher exposure ranges. We also observed some elevated risks for low birth weight but these estimates were less precise. Our findings strengthen the evidence that in-utero PFASs exposures affect fetal growth. Future studies are needed to evaluate whether these associations persist with the decline of PFOA and PFOS in populations and should also investigate newer types of fluorinated compounds introduced more recently
Biology · Birth weight · Cohort · Cohort study · Confidence interval · Danish · Environmental health · Fetus · Gestational age · In utero · Low birth weight · Obstetrics · Perfluorooctane · Pregnancy · Quartile · Air Quality and Health Impacts · Chemistry · Medicine · Per- and polyfluoroalkyl substances research · Toxic Organic Pollutants Impact · Internal Medicine · Physiology
Association Between Exposure to Per- and Polyfluoroalkyl Substances and Birth Outcomes
The associations between maternal and fetal exposure to endocrine-disrupting chemicals and asymmetric fetal growth restriction
High in Utero Exposure to Perfluoroalkyl Substances from Drinking Water and Birth Weight
| Obras citantes distintas | 3 |
|---|---|
| Citas por año | 0,75 |
| Intervalo de citas | 2022 - 2024 (3) |
| Velocidad de citación | recent |
| Altamente citado | No |
| Tipos de cita | Neutras: 3 |